Items where Division is "09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Molecular Immunology (Pluschke)"
Number of items at this level: 177. YesKaboré, J. M. T. and Siribié, M. and Hien, D. and Soulama, I. and Barry, N. and Baguiya, A. and Tiono, A. B. and Burri, C. and Tchouatieu, A. M. and Sirima, S. B.. (2023) Feasibility and acceptability of a strategy deploying multiple first-line artemisinin-based combination therapies for uncomplicated malaria in the health district of Kaya, Burkina Faso. Trop Med Infect Dis, 8 (4). p. 195. Day, C. J. and Poole, J. and Pluschke, G. and Jennings, M. P.. (2022) Investigation of Mycobacterium ulcerans glycan interactions using glycan array and surface plasmon resonance. In: Mycobacterium ulcerans. Methods in Molecular Biology, 2387. New York, NY, pp. 29-40. Eddyani, M. and Affolabi, D. and Ablordey, A. and Eyangoh, S. and Pluschke, G.. (2022) Laboratory investigations in Buruli ulcer. In: Leprosy and Buruli Ulcer. A practical guide. Cham, pp. 443-454. Fernandes, B. and Sousa, M. and Castro, R. and Schäfer, A. and Hauser, J. and Schulze, K. and Amacker, M. and Tamborrini, M. and Pluschke, G. and Alves, P. M. and Fleury, S. and Roldão, A.. (2022) Scalable process for high-yield production of PfCyRPA using insect cells for inclusion in a Malaria virosome-based vaccine candidate. Front Bioeng Biotechnol, 10. p. 879078. Hall, B. S. and Dos Santos, S. J. and Hsieh, L. T. and Manifava, M. and Ruf, M. T. and Pluschke, G. and Ktistakis, N. and Simmonds, R. E.. (2022) Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity. Autophagy, 18 (4). pp. 841-859. Hsieh, L. T. and Dos Santos, S. J. and Hall, B. S. and Ogbechi, J. and Loglo, A. D. and Salguero, F. J. and Ruf, M. T. and Pluschke, G. and Simmonds, R. E.. (2022) Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions. PLoS Pathog, 18. e1010280. Leuenberger, A. and Koné, B:V. and N'krumah, R. T. A. S. and Koffi, D. Y. and Bonfoh, B. and Utzinger, J. and Pluschke, G.. (2022) Perceived water-related risk factors of Buruli ulcer in two villages of south-central Côte d'Ivoire. PLoS Negl Trop Dis, 16 (12). e0010927. Muri, L. and Schubart, A. and Thorburn, C. and Zamurovic, N. and Holbro, T. and Kammüller, M. and Pluschke, G. and Ispasanie, E.. (2022) Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against Haemophilus influenzae type b. Front Immunol, 13. p. 1020580. Pluschke, G. and Röltgen, K.. (2022) Overview: development of drugs against Mycobacterium ulcerans. In: Mycobacterium ulcerans. Methods and protocols, 2387. New York, NY, pp. 185-187. Pluschke, G. and Röltgen, K.. (2022) Preface. In: Mycobacterium ulcerans: methods and protocols. New York, NY, V-VI. Portaels, F. and Pluschke, G.. (2022) History and geographic distribution of Buruli ulcer. In: Leprosy and Buruli Ulcer. A practical guide. Cham, pp. 421-430. Röltgen, K. and Johnson, P. D. R. and Pluschke, G.. (2022) Epidemiology of Buruli ulcer. In: Leprosy and Buruli Ulcer. A practical guide. Cham, pp. 541-550. Röltgen, K. and Pluschke, G.. (2022) Overview: mycolactone, the macrolide toxin of Mycobacterium ulcerans. In: Mycobacterium ulcerans. Methods and protocols, 2387. New York, NY, pp. 105-108. Röltgen, Katharina and Pluschke, Gerd. (2022) Overview: Mycobacterium ulcerans disease (buruli ulcer). In: Mycobacterium ulcerans: methods and protocols. New York, NY, pp. 3-6. Toppino, S. and Koffi, D. Y. and Kone, B. V. and N'Krumah, R. T. A. S. and Coulibaly, I. D. and Tobian, F. and Pluschke, G. and Stojkovic, M. and Bonfoh, B. and Junghanss, T.. (2022) Community-based wound management in a rural setting of Côte d'Ivoire. PLoS Negl Trop Dis, 16 (10). e0010730. Toppino, S. and N'Krumah, R. T. A. S. and Kone, B. V. and Koffi, D. Y. and Coulibaly, I. D. and Tobian, F. and Pluschke, G. and Stojkovic, M. and Bonfoh, B. and Junghanss, T.. (2022) Skin wounds in a rural setting of Côte d'Ivoire: population-based assessment of the burden and clinical epidemiology. PLoS Negl Trop Dis, 16 (10). e0010608. Warryn, L.. (2022) Competitive ELISA for the detection and quantification of Mycobacterium ulcerans mycolactone. In: Mycobacterium ulcerans. Methods in Molecular Biology, 2387. New York, NY, pp. 151-161. Warryn, L. and Pluschke, G.. (2022) Efficacy of an acid-oxidising solution (AOS) against Mycobacterium ulcerans. Antimicrob Agents Chemother, 66 (1). e00870-21. Brunetti, Giulio and Padovani, Francesco and De Pastina, Annalisa and Rotella, Chiara and Monahan, Amy and Hoffman, Stephen L. and Jongo, Said A. and Abdulla, Salim and Corradin, Giampietro and Pluschke, Gerd and Daubenberger, Claudia and Hegner, Martin. (2021) Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines. Nanoscale, 13 (4). pp. 2338-2349. Day, C. J. and Röltgen, K. and Pluschke, G. and Jennings, M. P.. (2021) The cell surface protein MUL_3720 confers binding of the skin pathogen; Mycobacterium ulcerans; to sulfated glycans and keratin. PLoS Negl Trop Dis, 15 (2). e0009136. Ispasanie, E. and Muri, L. and Schubart, A. and Thorburn, C. and Zamurovic, N. and Holbro, T. and Kammüller, M. and Pluschke, G.. (2021) Alternative complement pathway inhibition does not abrogate meningococcal killing by serum of vaccinated individuals. Front Immunol, 12. p. 747594. Please, H. R. and Vas Nunes, J. H. and Patel, R. and Pluschke, G. and Tholley, M. and Ruf, M. T. and Bolton, W. and Scott, J. A. and Grobusch, M. P. and Bolkan, H. A. and Brown, J. M. and Jayne, D. G.. (2021) Chronic wounds in Sierra Leone: searching for Buruli ulcer, a NTD caused by Mycobacterium ulcerans, at Masanga Hospital. PLoS Negl Trop Dis, 15 (10). e0009862. Warryn, L. and Dangy, J. P. and Gersbach, P. and Gehringer, M. and Altmann, K. H. and Pluschke, G.. (2021) An antigen capture assay for the detection of mycolactone, the polyketide toxin of Mycobacterium ulcerans. J Immunol, 206 (11). pp. 2753-2762. Borel, Nicole and Sauer-Durand, Anna Maria and Hartel, Mark and Kuratli, Jasmin and Vaupel, Peter and Scherr, Nicole and Pluschke, Gerd. (2020) wIRA: hyperthermia as a treatment option for intracellular bacteria, with special focus on Chlamydiae and Mycobacteria. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 37. pp. 373-383. Chaguza, Chrispin and Yang, Marie and Cornick, Jennifer E. and du Plessis, Mignon and Gladstone, Rebecca A. and Kwambana-Adams, Brenda A. and Lo, Stephanie W. and Ebruke, Chinelo and Tonkin-Hill, Gerry and Peno, Chikondi and Senghore, Madikay and Obaro, Stephen K. and Ousmane, Sani and Pluschke, Gerd and Collard, Jean-Marc and Sigaùque, Betuel and French, Neil and Klugman, Keith P. and Heyderman, Robert S. and McGee, Lesley and Antonio, Martin and Breiman, Robert F. and von Gottberg, Anne and Everett, Dean B. and Kadioglu, Aras and Bentley, Stephen D.. (2020) Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism. Communications biology, 3. p. 559. Röltgen, Katharina and Pluschke, Gerd. (2020) Buruli ulcer: the efficacy of innate immune defense may be a key determinant for the outcome of infection with Mycobacterium ulcerans. Frontiers in Microbiology, 11. p. 1018. Röltgen, Katharina and Pluschke, Gerd and Spencer, John Stewart and Brennan, Patrick Joseph and Avanzi, Charlotte. (2020) The immunology of other mycobacteria: M. ulcerans, M. leprae. Seminars in immunopathology, 42 (3). pp. 333-353. Tamborrini, Marco and Hauser, Julia and Schäfer, Anja and Amacker, Mario and Favuzza, Paola and Kyungtak, Kwak and Fleury, Sylvain and Pluschke, Gerd. (2020) Vaccination with virosomally formulated recombinant CyRPA elicits protective anti against Plasmodium falciparum parasites in preclinical in vitro and in vivo modelsbodies. NPJ vaccines, 5. p. 9. Vandelannoote, Koen and Pluschke, Gerd and Bolz, Miriam and Bratschi, Martin W. and Kerber, Sarah and Stinear, Timothy P. and de Jong, Bouke C.. (2020) Introduction of Mycobacterium ulcerans disease in the Bankim Health District of Cameroon follows damming of the Mapé river. PLoS neglected tropical diseases, 14 (9). e0008501. Warryn, Louisa and Dangy, Jean-Pierre and Gersbach, Philipp and Gehringer, Matthias and Schäfer, Anja and Ruf, Marie-Thérèse and Ruggli, Nicolas and Altmann, Karl-Heinz and Pluschke, Gerd. (2020) Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 14 (6). e0008357. Bolz, M. and Ruf, M. T.. (2019) Buruli ulcer in animals and experimental infection models. In: Buruli ulcer: mycobacterium ulcerans disease. Cham, pp. 159-182. Gehringer, Matthias and Mäder, Patrick and Gersbach, Philipp and Pfeiffer, Bernhard and Scherr, Nicole and Dangy, Jean-Pierre and Pluschke, Gerd and Altmann, Karl-Heinz. (2019) Configurationally stabilized analogs of M. ulcerans exotoxins mycolactones A and B reveal the importance of side chain geometry for mycolactone virulence. Organic Letters, 21 (15). pp. 5853-5857. Gruenberg, Maria and Lerch, Anita and Beck, Hans-Peter and Felger, Ingrid. (2019) Amplicon deep sequencing improves Plasmodium falciparum genotyping in clinical trials of antimalarial drugs. Scientific Reports, 9. p. 17790. Guenin-Macé, L. and Ruf, M. T. and Pluschke, G. and Demangel, C.. (2019) Mycolactone : more than just a cytotoxin. In: Buruli ulcer: mycobacterium ulcerans disease. Cham, pp. 117-134. Ondari, Edna M. and Klemm, Elizabeth J. and Msefula, Chisomo L. and El Ghany, Moataz Abd and Heath, Jennifer N. and Pickard, Derek J. and Barquist, Lars and Dougan, Gordon and Kingsley, Robert A. and MacLennan, Calman A.. (2019) Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive; Salmonella; Typhimurium ST313. Wellcome Open Research, 4. p. 74. Piazena, Helmut and Müller, Werner and Pendl, Wolfgang and von Ah, Sereina and Cap, Veronika H. and Hug, Petra J. and Sidler, Xaver and Pluschke, Gerd and Vaupel, Peter. (2019) Thermal field formation during wIRA-hyperthermia : temperature measurements in skin and subcutis of piglets as a basis for thermotherapy of superficial tumors and local skin infections caused by thermosensitive microbial pathogens. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 36 (1). pp. 938-952. Röltgen, K. and Cruz, I. and Ndung'u, J. M. and Pluschke, G.. (2019) Laboratory diagnosis of Buruli ulcer : challenges and future perspectives. In: Buruli ulcer: mycobacterium ulcerans disease. Cham, pp. 183-202. Röltgen, K. and Pluschke, G.. (2019) Buruli ulcer : history and disease burden. In: Buruli ulcer: mycobacterium ulcerans disease. Cham, pp. 1-42. Scherr, N. and Pluschke, G.. (2019) Buruli ulcer. In: Neglected tropical diseases: drug discovery and development. Hoboken, pp. 327-347. Tabah, E. N. and Johnson, C. R. and Degnonvi, H. and Pluschke, G. and Röltgen, K.. (2019) Buruli ulcer in Africa. In: Buruli ulcer: mycobacterium ulcerans disease. Cham, pp. 43-60. Ispasanie, Emma and Micoli, Francesca and Lamelas, Araceli and Keller, Dominique and Berti, Francesco and De Riccio, Riccardo and Di Benedettoi, Roberta and Rondini, Simona and Pluschke, Gerd. (2018) Spontaneous point mutations in the capsule synthesis locus leading to structural and functional changes of the capsule in serogroup A meningococcal populations. Virulence, 9 (1). pp. 1138-1149. Lamelas, Araceli and Hamid, Abdul-Wahab M. and Dangy, Jean-Pierre and Hauser, Julia and Jud, Maja and Röltgen, Katharina and Hodgson, Abraham and Junghanss, Thomas and Harris, Simon R. and Parkhill, Julian and Bentley, Stephen D. and Pluschke, Gerd. (2018) Loss of genomic diversity in a Neisseria meningitidis clone through a colonization bottleneck. Genome biology and evolution, 10 (8). pp. 2102-2109. Pinho-Nascimento, Carlos Augusto and Bratschi, Martin W. and Höfer, Rene and Soares, Caroline Cordeiro and Warryn, Louisa and Pečerska, Jūlija and Minyem, Jacques C. and Paixão, Izabel C. N. P. and Baroni de Moraes, Marcia Terezinha and Um Boock, Alphonse and Niel, Christian and Pluschke, Gerd and Röltgen, Katharina. (2018) Transmission of hepatitis B and D viruses in an African rural community. mSystems, 3 (5). e00120-18. Röltgen, Katharina and Rose, Natalie and Ruggieri, Alessia and Warryn, Louisa and Scherr, Nicole and Pinho-Nascimento, Carlos Augusto and Tamborrini, Marco and Jaenisch, Thomas and Pluschke, Gerd. (2018) Development of dengue virus serotype-specific NS1 capture assays for the rapid and highly sensitive identification of the infecting serotype in human sera. Journal of immunology (Baltimore, Md. : 1950), 200 (11). pp. 3857-3866. Scherr, Nicole and Bieri, Raphael and Thomas, Sangeeta S. and Chauffour, Aurélie and Kalia, Nitin Pal and Schneide, Paul and Ruf, Marie-Thérèse and Lamelas, Araceli and Manimekalai, Malathy S. S. and Grüber, Gerhard and Ishii, Norihisa and Suzuki, Koichi and Tanner, Marcel and Moraski, Garrett C. and Miller, Marvin J. and Witschel, Matthias and Jarlier, Vincent and Pluschke, Gerd and Pethe, Kevin. (2018) Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer. Nature Communications, 9. p. 5370. Tabah, Earnest Njih and Nsagha, Dickson Shey and Bissek, Anne-Cécile Zoung-Kanyi and Njamnshi, Theophilus Ngeh and Njih, Irine Ngani-Nformi and Pluschke, Gerd and Njamnshi, Alfred Kongnyu. (2018) Community knowledge, perceptions and attitudes regarding leprosy in rural Cameroon: the case of Ekondotiti and Mbonge health districts in the South-west region. PLoS neglected tropical diseases, 12 (2). e0006233. Addison, Naa Okaikor and Pfau, Stefanie and Koka, Eric and Aboagye, Samuel Yaw and Kpeli, Grace and Pluschke, Gerd and Yeboah-Manu, Dorothy and Junghanss, Thomas. (2017) Assessing and managing wounds of Buruli ulcer patients at the primary and secondary health care levels in Ghana. PLoS Neglected Tropical Diseases, 11 (2). e0005331. Bibert, Stéphanie and Bratschi, Martin W. and Aboagye, Samuel Y. and Collinet, Emilie and Scherr, Nicole and Yeboah-Manu, Dorothy and Beuret, Christian and Pluschke, Gerd and Bochud, Pierre-Yves. (2017) Susceptibility to mycobacterium ulcerans disease (buruli ulcer) is associated with IFNG and iNOS gene polymorphisms. Frontiers in Microbiology, 8. p. 1903. Bieri, Raphael and Scherr, Nicole and Ruf, Marie-Thérèse and Dangy, Jean-Pierre and Gersbach, Philipp and Gehringer, Matthias and Altmann, Karl-Heinz and Pluschke, Gerd. (2017) The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR. ACS chemical biology, 12 (5). pp. 1297-1307. Favuzza, Paola and Guffart, Elena and Tamborrini, Marco and Scherer, Bianca and Dreyer, Anita M. and Rufer, Arne C. and Erny, Johannes and Hoernschemeyer, Joerg and Thoma, Ralf and Schmid, Georg and Gsell, Bernard and Lamelas, Araceli and Benz, Joerg and Joseph, Catherine and Matile, Hugues and Pluschke, Gerd and Rudolph, Markus G.. (2017) Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody. eLife, 6. e20383. Kpeli, Grace and Buultjens, Andrew H. and Giulieri, Stefano and Owusu-Mireku, Evelyn and Aboagye, Samuel Y. and Baines, Sarah L. and Seemann, Torsten and Bulach, Dieter and Gonçalves da Silva, Anders and Monk, Ian R. and Howden, Benjamin P. and Pluschke, Gerd and Yeboah-Manu, Dorothy and Stinear, Timothy. (2017) Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana. PeerJ, 5. e3047. Lamelas, Araceli and Hauser, Julia and Dangy, Jean-Pierre and Hamid, Abdul-Wahab M. and Röltgen, Katharina and Abdul Sater, Mohamad R. and Hodgson, Abraham and Sie, Ali and Junghanss, Thomas and Harris, Simon R. and Parkhill, Julian and Bentley, Stephen D. and Pluschke, Gerd. (2017) Emergence and genomic diversification of a virulent serogroup W:ST-2881(CC175) Neisseria meningitidis clone in the African meningitis belt. Microbial genomics, 3 (8). e000120. Owusu, Enid and Newman, Mercy J. and Akumwena, Amos and Bannerman, Elizabeth and Pluschke, Gerd. (2017) Evaluating decontamination protocols for the isolation of Mycobacterium ulcerans from swabs. BMC microbiology, 17. p. 2. Ruf, Marie-Thérèse and Andreoli, Arianna and Vujic, Gabriel and Itin, Peter and Pluschke, Gerd and Schmid, Peter. (2017) Exudate collection using wound sponges - An easy, non-invasive and reliable method to explore protease activities in ulcers. Wound Repair and Regeneration, 25 (2). pp. 320-326. Ruf, Marie-Thérèse and Steffen, Christina and Bolz, Miriam and Schmid, Peter and Pluschke, Gerd. (2017) Infiltrating leukocytes surround early Buruli ulcer lesions, but are unable to reach the mycolactone producing mycobacteria. Virulence, 8 (8). pp. 1918-1926. Röltgen, Katharina and Pluschke, Gerd and Johnson, Paul D. R. and Fyfe, Janet. (2017) Mycobacterium ulcerans DNA in bandicoot excreta in Buruli ulcer-endemic area, Northern Queensland, Australia. Emerging infectious diseases, 23 (12). pp. 2042-2045. Aboagye, Samuel Yaw and Danso, Emelia and Ampah, Kobina Assan and Nakobu, Zuliehatu and Asare, Prince and Otchere, Isaac Darko and Röltgen, Katharina and Yirenya-Tawiah, Dzidzo and Yeboah-Manu, Dorothy. (2016) Isolation of nontuberculous Mycobacteria from the environment of Buruli ulcer endemic communities in Ghana. Applied and Environmental Microbiology, 82 (14). pp. 4320-4329. Ampah, Kobina Assan and Asare, Prince and Binnah, Daniel De-Graft and Maccaulley, Samuel and Opare, William and Röltgen, Katharina and Pluschke, Gerd and Yeboah-Manu, Dorothy. (2016) Burden and historical trend of Buruli Ulcer prevalence in selected communities along the Offin River of Ghana. PLoS neglected tropical diseases, 10 (4). e0004603. Ampah, Kobina Assan and Nickel, Beatrice and Asare, Prince and Ross, Amanda and De-Graft, Daniel and Kerber, Sarah and Spallek, Ralf and Singh, Mahavir and Pluschke, Gerd and Yeboah-Manu, Dorothy and Röltgen, Katharina. (2016) A sero-epidemiological approach to explore transmission of Mycobacterium ulcerans. PLoS neglected tropical diseases, 10 (1). e0004387. Ampah, Kobina Assan and Pinho-Nascimento, Carlos Augusto and Kerber, Sarah and Asare, Prince and De-Graft, Daniel and Adu-Nti, Frank and Paixão, Izabel C. N. P. and Niel, Christian and Yeboah-Manu, Dorothy and Pluschke, Gerd and Röltgen, Katharina. (2016) Limited genetic diversity of Hepatitis b virus in the general population of the offin river valley in Ghana. PLoS ONE, 11 (6). e0156864. Bieri, Raphael and Bolz, Miriam and Ruf, Marie-Thérèse and Pluschke, Gerd. (2016) Interferon-γ is a crucial activator of early host immune defense against Mycobacterium ulcerans infection in mice. PLoS neglected tropical diseases, 10 (2). e0004450. Bolz, Miriam and Bénard, Angèle and Dreyer, Anita M. and Kerber, Sarah and Vettiger, Andrea and Oehlmann, Wulf and Singh, Mahavir and Duthie, Malcolm S. and Pluschke, Gerd. (2016) Vaccination with the surface proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans induces antibodies but fails to provide protection against Buruli ulcer. PLoS neglected tropical diseases, 10 (2). e0004431. Bolz, Miriam and Ruggli, Nicolas and Borel, Nicole and Pluschke, Gerd and Ruf, Marie-Thérèse. (2016) Local cellular immune responses and pathogenesis of buruli ulcer lesions in the experimental mycobacterium ulcerans pig infection model. PLoS neglected tropical diseases, 10 (4). e0004678. Bénard, Angèle and Sala, Claudia and Pluschke, Gerd. (2016) Mycobacterium ulcerans mouse model refinement for pre-clinical profiling of vaccine candidates. PLoS ONE, 11 (11). e0167059. Chaguza, Chrispin and Cornick, Jennifer E. and Harris, Simon R. and Andam, Cheryl P. and Bricio-Moreno, Laura and Yang, Marie and Yalcin, Feyruz and Ousmane, Sani and Govindpersad, Shanil and Senghore, Madikay and Ebruke, Chinelo and Du Plessis, Mignon and Kiran, Anmol M. and Pluschke, Gerd and Sigauque, Betuel and McGee, Lesley and Klugman, Keith P. and Turner, Paul and Corander, Jukka and Parkhill, Julian and Collard, Jean-Marc and Antonio, Martin and von Gottberg, Anne and Heyderman, Robert S. and French, Neil and Kadioglu, Aras and Hanage, William P. and Everett, Dean B. and Bentley, Stephen D. and PAGe Consortium, . (2016) Understanding pneumococcal serotype 1 biology through population genomic analysis. BMC infectious diseases, 16. p. 649. Dangy, Jean-Pierre and Scherr, Nicole and Gersbach, Philipp and Hug, Melanie N. and Bieri, Raphael and Bomio, Claudio and Li, Jun and Huber, Sylwia and Altmann, Karl-Heinz and Pluschke, Gerd. (2016) Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 10 (6). e0004808. Favuzza, Paola and Blaser, Simon and Dreyer, Anita M. and Riccio, Guy and Tamborrini, Marco and Thoma, Ralf and Matile, Hugues and Pluschke, Gerd. (2016) Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA. Malaria journal, 15. p. 161. Kpeli, G. and Darko Otchere, I. and Lamelas, A. and Buultjens, A. L. and Bulach, D. and Baines, S. L. and Seemann, T. and Giulieri, S. and Nakobu, Z. and Aboagye, S. Y. and Owusu-Mireku, E. and Pluschke, G. and Stinear, T. P. and Yeboah-Manu, D.. (2016) Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana. New microbes and new infections, 13. pp. 92-101. Lamelas, Araceli and Ampah, Kobina Assan and Aboagye, Samuel and Kerber, Sarah and Danso, Emelia and Asante-Poku, Adwoa and Asare, Prince and Parkhill, Julian and Harris, Simon R. and Pluschke, Gerd and Yeboah-Manu, Dorothy and Röltgen, Katharina. (2016) Spatiotemporal co-existence of two Mycobacterium ulcerans clonal complexes in the Offin River Valley of Ghana. PLoS Neglected Tropical Diseases, 10 (7). e0004856. N'krumah, Raymond T. A. S. and Koné, Brama and Tiembre, Issaka and Cissé, Guéladio and Pluschke, Gerd and Tanner, Marcel and Utzinger, Jürg. (2016) Socio-environmental factors associated with the risk of contracting Buruli ulcer in Tiassalé, South Côte d'Ivoire : a case-control study. PLoS neglected tropical diseases, 10 (1). e0004327. Rose, Natalie and Pinho-Nascimento, Carlos Augusto and Ruggieri, Alessia and Favuzza, Paola and Tamborrini, Marco and Roth, Hanna and Baroni de Moraes, Marcia Terezinha and Matile, Hugues and Jänisch, Thomas and Pluschke, Gerd and Röltgen, Katharina. (2016) Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization. BMC biotechnology, 16. p. 83. Ruf, Marie-Thérèse and Bolz, Miriam and Vogel, Moritz and Bayi, Pierre F. and Bratschi, Martin W. and Sopho, Ghislain Emmanuel and Yeboah-Manu, Dorothy and Um Boock, Alphonse and Junghanss, Thomas and Pluschke, Gerd. (2016) Spatial distribution of Mycobacterium ulcerans in Buruli ulcer lesions: implications for laboratory diagnosis. PLoS Neglected Tropical Diseases, 10 (6). e0004767. Scherr, Nicole and Pluschke, Gerd and Panda, Manoranjan. (2016) Comparative study of activities of a diverse set of antimycobacterial agents against Mycobacterium tuberculosis and Mycobacterium ulcerans. Antimicrobial agents and chemotherapy, 60 (5). pp. 3132-3137. Tabah, Earnest Njih and Nsagha, Dickson Shey and Bissek, Anne-Cecile Zoung-Kanyi and Bratschi, Martin W. and Njamnshi, Theophilus Ngeh and Plushke, Gerd and Njamnshi, Alfred Kongnyu. (2016) The burden of leprosy in Cameroon: fifteen years into the post-elimination era. PLoS Neglected Tropical Diseases, 10 (10). e0005012. Tabah, Earnest Njih and Nsagha, Dickson Shey and Bissek, Anne-Cécile Zoung-Kanyi and Njamnshi, Alfred Kongnyu and Bratschi, Martin W. and Pluschke, Gerd and Um Boock, Alphonse. (2016) Buruli ulcer in Cameroon: the development and impact of the National Control Programme. PLoS neglected tropical diseases, 10 (1). e0004224. Vogel, Moritz and Bayi, Pierre F. and Ruf, Marie-Thérèse and Bratschi, Martin W. and Bolz, Miriam and Um Boock, Alphonse and Zwahlen, Marcel and Pluschke, Gerd and Junghanss, Thomas. (2016) Local heat application for the treatment of Buruli ulcer : results of a phase II open label single center non comparative clinical trial. Clinical Infectious Diseases, 62 (3). pp. 342-350. Andreoli, A. and Ruf, M. T. and Itin, P. and Pluschke, G. and Schmid, P.. (2015) Phosphorylation of the ribosomal protein S6, a marker of mTOR (mammalian target of rapamycin) pathway activation, is strongly increased in hypertrophic scars and keloids. British journal of dermatology, Vol. 172, H. 5. pp. 1415-1417. Andreoli, Arianna and Mou, Ferdinand and Minyem, Jacques C. and Wantong, Fidèle G. and Noumen, Djeunga and Awah, Paschal K. and Pluschke, Gerd and Boock, Alphonse Um and Bratschi, Martin W.. (2015) Complete healing of a laboratory-confirmed Buruli ulcer lesion after receiving only herbal household remedies. PLoS neglected tropical diseases, 9 (11). e0004102. Bolz, Miriam and Bratschi, Martin W. and Kerber, Sarah and Minyem, Jacques C. and Um Boock, Alphonse and Vogel, Moritz and Bayi, Pierre Franklin and Junghanss, Thomas and Brites, Daniela and Harris, Simon R. and Parkhill, Julian and Pluschke, Gerd and Lamelas Cabello, Araceli. (2015) Locally confined clonal complexes of Mycobacterium ulcerans in two Buruli ulcer endemic regions of Cameroon. PLoS neglected tropical diseases, Vol. 9, H. 6 , e0003802. Bolz, Miriam and Kerber, Sarah and Zimmer, Gert and Pluschke, Gerd. (2015) Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease. PLoS neglected tropical diseases, Vol. 9, H. 8 , e0004011. Cornick, J. E. and Chaguza, C. and Harris, S. R. and Yalcin, F. and Senghore, M. and Kiran, A. M. and Govindpershad, S. and Ousmane, S. and du Plessis, M. and Pluschke, G. and Ebruke, C. and McGee, L. and Sigauque, B. and Collard, J. M. and Antonio, M. and von Gottberg, A. and French, N. and Klugman, K. P. and Heyderman, R. S. and Bentley, S. D. and Everett, D. B.. (2015) Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae. Microbial genomics, 1 (2). pp. 1-13. Crick, Peter J. and Guan, Xue Li. (2015) Lipid metabolism in mycobacteria-Insights using mass spectrometry-based lipidomics. Biochimica et biophysica acta, 1861. pp. 60-67. Dreyer, Anita and Röltgen, Katharina and Dangy, Jean Pierre and Ruf, Marie Thérèse and Scherr, Nicole and Bolz, Miriam and Tobias, Nicholas Jay and Moes, Charles and Vettiger, Andrea and Stinear, Timothy Paul and Pluschke, Gerd. (2015) Identification of the Mycobacterium ulcerans protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer. PLoS neglected tropical diseases, Vol. 9, H. 2 , e0003477. Heinz, Leonhard X. and Baumann, Christoph L. and Köberlin, Marielle S. and Snijder, Berend and Gawish, Riem and Shui, Guanghou and Sharif, Omar and Aspalter, Irene M. and Müller, André C. and Kandasamy, Richard K. and Breitwieser, Florian P. and Pichlmair, Andreas and Bruckner, Manuela and Rebsamen, Manuele and Blüml, Stephan and Karonitsch, Thomas and Fauster, Astrid and Colinge, Jacques and Bennett, Keiryn L. and Knapp, Sylvia and Wenk, Markus R. and Superti-Furga, Giulio. (2015) The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity. Cell reports, Vol. 11, H. 12. pp. 1919-1928. Ogbechi, Joy and Ruf, Marie-Thérèse and Hall, Belinda S. and Bodman-Smith, Katherine and Vogel, Moritz and Wu, Hua-Lin and Stainer, Alexander and Esmon, Charles T. and Ahnström, Josefin and Pluschke, Gerd and Simmonds, Rachel E.. (2015) Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions. PLoS Pathogens, Vol. 11, H. 7 , e1005011. Owusu, E. and Newman, M. J. and Akumwena, A. and Pfosu-Appiah, L. and Pluschke, G.. (2015) Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana. International journal of mycobacteriology, 4 (3). pp. 184-190. Röltgen, K. and Pluschke, G.. (2015) Epidemiology and disease burden of Buruli ulcer : a review. Research and Reports in Tropical Medicine, 6. pp. 59-73. Röltgen, K. and Pluschke, G.. (2015) Mycobacterium ulcerans disease (Buruli ulcer): potential reservoirs and vectors. Current clinical microbiology reports, 2. pp. 35-43. Sater, Mohamad R. Abdul and Lamelas, Araceli and Wang, Guilin and Clark, Tyson A. and Röltgen, Katharina and Mane, Shrikant and Korlach, Jonas and Pluschke, Gerd and Schmid, Christoph D.. (2015) DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates. PLoS ONE, 10 (12). e0144612. Scherr, Nicole and Pluschke, Gerd and Thompson, Charles J. and Ramón-García, Santiago. (2015) Selamectin is the avermectin with the best potential for Buruli ulcer treatment. PLoS neglected tropical diseases, Vol. 9, H. 8 , e0003996. Silbereisen, Angelika and Tamborrini, Marco and Wittwer, Matthias and Schürch, Nadia and Pluschke, Gerd. (2015) Development of a bead-based Luminex assay using lipopolysaccharide specific monoclonal antibodies to detect biological threats from Brucella species. BMC microbiology, 15. p. 198. Tamborrini, Marco and Geib, Nina and Marrero-Nodarse, Aniebrys and Jud, Maja and Hauser, Julia and Aho, Celestine and Lamelas, Araceli and Zuniga, Armando and Pluschke, Gerd and Ghasparian, Arin and Robinson, John A.. (2015) A synthetic virus-like particle streptococcal vaccine candidate using B-cell epitopes from the proline-rich region of pneumococcal surface protein A. Vaccines, 3 (4). pp. 850-874. Tuffour, Joseph and Owusu-Mireku, Evelyn and Ruf, Marie-Therese and Aboagye, Samuel and Kpeli, Grace and Akuoku, Victor and Pereko, Janet and Paintsil, Albert and Bonney, Kofi and Ampofo, William and Pluschke, Gerd and Yeboah-Manu, Dorothy. (2015) Challenges associated with management of Buruli ulcer/human immunodeficiency virus coinfection in a treatment center in Ghana : a case series study. American journal of tropical medicine and hygiene, 93 (2). pp. 216-223. Walker, Karen M. and Okitsu, Shinji and Porter, David W. and Duncan, Christopher and Amacker, Mario and Pluschke, Gerd and Cavanagh, David R. and Hill, Adrian V. S. and Todryk, Stephen M.. (2015) Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships. Immunology, Vol. 145, H. 1. pp. 71-81. Andreoli, Arianna and Ruf, Marie-Thérèse and Sopoh, Ghislain Emmanuel and Schmid, Peter and Pluschke, Gerd. (2014) Immunohistochemical monitoring of wound healing in antibiotic treated buruli ulcer patients. PLoS neglected tropical diseases, Vol. 8, H. 4 , e2809. Bolz, Miriam and Ruggli, Nicolas and Ruf, Marie-Thérèse and Ricklin, Meret E. and Zimmer, Gert and Pluschke, Gerd. (2014) Experimental infection of the pig with Mycobacterium ulcerans : a novel model for studying the pathogenesis of Buruli ulcer disease. PLoS neglected tropical diseases, Vol. 8, H. 7 , e2968. Bratschi, Martin W. and Bolz, Miriam and Grize, Leticia and Kerber, Sarah and Minyem, Jacques C. and Um Boock, Alphonse and Yeboah-Manu, Dorothy and Ruf, Marie-Thérèse and Pluschke, Gerd. (2014) Primary cultivation : factors affecting contamination and Mycobacterium ulcerans growth after long turnover time of clinical specimens. BMC infectious diseases, Vol. 14 , 636. Bratschi, Martin W. and Ruf, Marie-Thérèse and Andreoli, Arianna and Minyem, Jacques C. and Kerber, Sarah and Wantong, Fidèle G. and Pritchard, James and Chakwera, Victoria and Beuret, Christian and Wittwer, Matthias and Noumen, Djeunga and Schürch, Nadia and Um Book, Alphonse and Pluschke, Gerd. (2014) Mycobacterium ulcerans persistence at a village water source of Buruli ulcer patients. PLoS neglected tropical diseases, Vol. 8, H. 3 , e2756. Hadadi, Noushin and Cher Soh, Keng and Seijo, Marianne and Zisaki, Aikaterini and Guan, Xueli and Wenk, Markus R. and Hatzimanikatis, Vassily. (2014) A computational framework for integration of lipidomics data into metabolic pathways. Metabolic engineering, Vol. 23. pp. 1-8. Hilty, Markus and Wüthrich, Daniel and Salter, Susannah J. and Engel, Hansjürg and Campbell, Samuel and Sá-Leão, Raquel and de Lencastre, Hermínia and Hermans, Peter and Sadowy, Ewa and Turner, Paul and Chewapreecha, Claire and Diggle, Mathew and Pluschke, Gerd and McGee, Lesley and Köseoğlu Eser, Özgen and Low, Donald E. and Smith-Vaughan, Heidi and Endimiani, Andrea and Küffer, Marianne and Dupasquier, Mélanie and Beaudoing, Emmanuel and Weber, Johann and Bruggmann, Rémy and Hanage, William P. and Parkhill, Julian and Hathaway, Lucy J. and Mühlemann, Kathrin and Bentley, Stephen D.. (2014) Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages. Genome biology and evolution, Vol. 6, H. 12. pp. 3281-3294. Ispasanie, Emma and Pluschke, Gerd and Hodgson, Abraham and Sie, Ali and MacLennan, Calman and Koeberling, Oliver. (2014) Characterization of vaccine antigens of meningococcal serogroup W isolates from Ghana and Burkina Faso from 2003 to 2009. Faculty of 1000, Vol. 3. p. 264. Itokazu, Y. and Käkelä, R. and Piironen, J. and Guan, X. L. and Kiiskinen, P. and Vornanen, M.. (2014) Gill tissue lipids of salmon (Salmo salar L.) presmolts and smolts from anadromous and landlocked populations. Comparative biochemistry and physiology : CBP. Part A, Molecular & integrative physiology, Vol. 172. pp. 39-45. Junghanss, T. and Johnson, R. C. and Pluschke, G.. (2014) Mycobacterium ulcerans disease. In: Manson's tropical diseases. - 23rd ed.. [Edinburgh], pp. 519-531. Kenu, Ernest and Nyarko, Kofi Mensah and Seefeld, Linda and Ganu, Vincent and Käser, Michael and Lartey, Margaret and Calys-Tagoe, Benedict Nii Laryea and Koram, Kwodwo and Adanu, Richard and Razum, Oliver and Afari, Edwin and Binka, Fred N.. (2014) Risk factors for buruli ulcer in ghana-a case control study in the suhum-kraboa-coaltar and akuapem South districts of the eastern region. PLoS neglected tropical diseases, Vol. 8, H. 11 , e3279. Koeberling, Oliver and Ispasanie, Emma and Hauser, Julia and Rossi, Omar and Pluschke, Gerd and Caugant, Dominique A. and Saul, Allan and Maclennan, Calman A.. (2014) A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on Generalized Modules for Membrane Antigens (GMMA). Vaccine, 32 (23). pp. 2688-2695. Lamelas, Araceli and Harris, Simon R. and Röltgen, Katharina and Dangy, Jean-Pierre and Hauser, Julia and Kingsley, Robert A. and Connor, Thomas R. and Sie, Ali and Hodgson, Abraham and Dougan, Gordon and Parkhill, Julian and Bentley, Stephen D. and Pluschke, Gerd. (2014) Emergence of a new epidemic Neisseria meningitidis serogroup A clone in the African meningitis belt : high-resolution picture of genomic changes that mediate immune evasion. mBio, Vol. 5, H. 5 , e01974-14. Nakamura, Yuki and Teo, Norman Z. W. and Shui, Guanghou and Chua, Christine H. L. and Cheong, Wei-Fun and Parameswaran, Sriram and Koizumi, Ryota and Ohta, Hiroyuki and Wenk, Markus R. and Ito, Toshiro. (2014) Transcriptomic and lipidomic profiles of glycerolipids during Arabidopsis flower development. New phytologist : international journal of plant science, Vol. 203, H. 1. pp. 310-322. Ravindran, Madhu Sudhan and Rao, Srinivasa P. S. and Cheng, Xiamin and Shukla, Ankit and Cazenave-Gassiot, Amaury and Yao, Shao Q. and Wenk, Markus R.. (2014) Targeting lipid esterases in Mycobacteria grown under different physiological conditions using activity-based profiling with tetrahydrolipstatin (THL). Molecular & cellular proteomics, Vol. 13, H. 2. pp. 435-448. Ruf, M. T. and Andreoli, A. and Itin, P. and Pluschke, G. and Schmid, P.. (2014) Ribosomal protein S6 is hyperactivated and differentially phosphorylated in epidermal lesions of patients with psoriasis and atopic dermatitis. British journal of dermatology, Vol. 171, H. 6. pp. 1533-1536. Röltgen, Katharina and Bratschi, Martin W. and Ross, Amanda and Aboagye, Samuel Y. and Ampah, Kobina A. and Bolz, Miriam and Andreoli, Arianna and Pritchard, James and Minyem, Jacques C. and Noumen, Djeunga and Koka, Eric and Um Boock, Alphonse and Yeboah-Manu, Dorothy and Pluschke, Gerd. (2014) Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children. PLoS neglected tropical diseases, Vol. 8, H. 5 , e2904. Tanner, Lukas Bahati and Chng, Charmaine and Guan, Xue Li and Lei, Zhengdeng and Rozen, Steven G. and Wenk, Markus R.. (2014) Lipidomics identifies a requirement for peroxisomal function during influenza virus replication. Journal of Lipid Research, 55 (7). pp. 1357-1365. Vettiger, A. and Scherr, N. and Ruf, M. T. and Röltgen, K. and Pluschke, G.. (2014) Localization of mycobacterial antigens by immunofluorescence staining of agarose embedded cells. Mycobacterial diseases, Vol. 4, H. 3. pp. 3-4. Albrecht, Imke and Bieri, Raphael and Leu, Angela and Granacher, Philipp and Hagmann, Jörg and Kilimann, Manfred W. and Christofori, Gerhard. (2013) Paralemmin-1 is expressed in lymphatic endothelial cells and modulates cell migration, cell maturation and tumor lymphangiogenesis. Angiogenesis, Vol. 16, H. 4. pp. 795-807. Altmann, Danny and Aseffa, Abraham and Bash, Margaret and Basta, Nicole and Borrow, Ray and Broome, Claire and Caugant, Dominique and Clark, Tom and Collard, Jean-Marc and Djingarey, Mamoudou and Goldblatt, David and Greenwood, Brian and Griffiths, Ulla and Hajjeh, Rana and Hassan-King, Musa and Hugonnet, Stephane and Kimball, Ann Marie and LaForce, Marc and MacLennan, Calman and Maiden, Martin C. J. and Manigart, Olivier and Mayer, Leonard and Messonnier, Nancy and Moisi, Jennifer and Moore, Katie and Moto, Daugla Doumagoum and Mueller, Judith and Nascimento, Maria and Obaro, Stephen and Ouedraogo, Rasmata and Page, Anne-Laure and Perea, Willima and Pluschke, Gerd and Preziosi, Mari-Pierre and Sow, Samba and Stephens, David and Stuart, James and Thomson, Madeleiene and Tiendrebeogo, Sylvestre and Trape, Jean-Francois and Vernet, Guy. (2013) Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt. Vaccine : the official journal of the International Society for Vaccines, 31 (11). pp. 1453-1457. Bratschi, Martin W. and Bolz, Miriam and Minyem, Jacques C. and Grize, Leticia and Wantong, Fidèle G. and Kerber, Sarah and Njih Tabah, Earnest and Ruf, Marie-Thérèse and Mou, Ferdinand and Noumen, Djeunga and Um Boock, Alphonse and Pluschke, Gerd. (2013) Geographic distribution, age pattern and sites of lesions in a cohort of buruli ulcer patients from the mapé basin of cameroon. PLoS neglected tropical diseases, Vol. 7, H. 6 , e2252. Grandgirard, D. and Gäumann, R. and Coulibaly, B. and Dangy, J. P. and Sie, A. and Junghanss, T. and Schudel, H. and Pluschke, G. and Leib, S. L.. (2013) The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis. Mediators of inflammation, 2013, ID 312476. Guan, X. L. and Cestra, G. and Shui, G. and Kuhrs, A. and Schittenhelm, R. B. and Hafen, E. and Van der Goot, F. G. and Robinett, C. C. and Gatti, M. and Gonzales-Gaitan, M. and Wenk, M. R.. (2013) Biochemical membrane lipidomics during Drosophila development. Developmental cell, Vol. 24, H. 1. pp. 98-111. Guenin-Macé, Laure and Veyron-Churlet, Romain and Thoulouze, Maria-Isabel and Romet-Lemonne, Guillaume and Hong, Hui and Leadlay, Peter F. and Danckaert, Anne and Ruf, Marie-Thérèse and Mostowy, Serge and Zurzolo, Chiara and Bousso, Philippe and Chrétien, Fabrice and Carlier, Marie-France and Demangel, Caroline. (2013) Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation. Journal of Clinical Investigation, Vol. 123, H. 4. pp. 1501-1512. Herrmann, Mathias and Abdullah, Salim and Alabi, Abraham and Alonso, Pedro and Friedrich, Alexander W. and Fuhr, Günther and Germann, Anja and Kern, Winfried V. and Kremsner, Peter G. and Mandomando, Inacio and Mellmann, Alexander C. and Pluschke, Gerd and Rieg, Siegbert and Ruffing, Ulla and Schaumburg, Frieder and Tanner, Marcel and Peters, Georg and von Briesen, Hagen and von Eiff, Christof and von Müller, Lutz and Grobusch, Martin P.. (2013) Staphylococcal disease in Africa : another neglected 'tropical' disease. Future microbiology, Vol. 8. pp. 17-26. Huber, Charlotte A. and Pflüger, Valentin and Hamid, Abdul-Wahab M. and Forgor, Abudulai A. and Hodgson, Abraham and Sié, Ali and Junghanss, Thomas and Pluschke, Gerd. (2013) Lack of antigenic diversification of major outer membrane proteins during clonal waves of Neisseria meningitidis serogroup A colonization and disease. Pathogens and disease, Vol. 67. pp. 4-10. Micoli, Francesca and Romano, Maria Rosaria and Tontini, Marta and Cappelletti, Emilia and Gavini, Massimiliano and Proietti, Daniela and Rondini, Simona and Swennen, Erwin and Santini, Laura and Filippini, Sara and Balocchi, Cristiana and Adamo, Roberto and Pluschke, Gerd and Norheim, Gunnstein and Pollard, Andrew and Saul, Allan and Rappuoli, Rino and Maclennan, Calman A. and Berti, Francesco and Costantino, Paolo. (2013) Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 47. pp. 19077-19082. Porter, Jessica L. and Tobias, Nicholas J. and Pidot, Sacha J. and Falgner, Steffen and Tuck, Kellie L. and Vettiger, Andrea and Hong, Hui and Leadlay, Peter F. and Stinear, Timothy P.. (2013) The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis. PLoS ONE, Vol. 8, H. 7 , e70520. Ravindran, Madhu Sudhan and Tanner, Lukas Bahati and Wenk, Markus R.. (2013) Sialic Acid linkage in glycosphingolipids is a molecular correlate for trafficking and delivery of extracellular cargo. Traffic, Vol. 14, H. 11. pp. 1182-1191. Scherr, Nicole and Gersbach, Philipp and Dangy, Jean-Pierre and Bomio, Claudio and Li, Jun and Altmann, Karl-Heinz and Pluschke, Gerd. (2013) Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 7, H. 3 , e2143. Yeboah-Manu, Dorothy and Kpeli, Grace S. and Ruf, Marie-Thérèse and Asan-Ampah, Kobina and Quenin-Fosu, Kwabena and Owusu-Mireku, Evelyn and Paintsil, Albert and Lamptey, Isaac and Anku, Benjamin and Kwakye-Maclean, Cynthia and Newman, Mercy and Pluschke, Gerd. (2013) Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin. PLoS neglected tropical diseases, Vol. 7, H. 5 , e2191. Bauer, M. and Chicca, A. and Tamborrini, M. and Eisen, D. and Lerner, R. and Lutz, B. and Poetz, O. and Pluschke, G. and Gertsch, J.. (2012) Identification and qualification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors. Journal of biological chemistry, Vol. 287, H. 44. pp. 36944-36967. Berti, F. and Romano, M. R. and Micoli, F. and Pinto, V. and Cappelletti, E. and Gavini, M. and Proietti, D. and Pluschke, G. and MacLennan, C. A. and Costantino, P.. (2012) Relative stability of meningococcal serogroup A and X polysaccharides. Vaccine : the official journal of the International Society for Vaccines, 30. pp. 6409-6415. Bratschi, M. W. and Njih, Tabah and Bolz, M. and Stucki, D. and Borrell, S. and Gagneux, S. and Noumen-Djeunga, B. and Junghanss, T. and Um Boock, A. and Pluschke, G.. (2012) A case of cutaneous tuberculosis in a Buruli ulcer-endemic area. PLoS neglected tropical diseases, Vol. 6, H. 8 , e1751. Doig, K. D. and Holt, K. E. and Fyfe, J. A. and Lavender, C. J. and Eddyani, M. and Portaels, F. and Yeboah-Manu, D. and Pluschke, G. and Seemann, T. and Stinear, T. P.. (2012) On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer. BMC genomics, Vol. 13 , 257. Dreyer, A. M. and Matile, H. and Papastogiannidis, P. and Kamber, J. and Favuzza, P. and Voss, Till S. and Wittlin, S. and Pluschke, G.. (2012) Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen. Journal of immunology : official journal of the American Association of Immunologists, Vol. 188, H. 12. pp. 6225-6237. Guan, Xue Li and Wenk, Markus R.. (2012) Targeted and non-targeted analysis of membrane lipids using mass spectrometry. Methods in cell biology, Vol. 108. pp. 147-172. Jayachandran, Rajesh and Scherr, Nicole and Pieters, Jean. (2012) Elimination of intracellularly residing Mycobacterium tuberculosis through targeting of host and bacterial signaling mechanisms. Expert review of anti-infective therapy, Vol. 10, H. 9. pp. 1007-1022. Kenu, E. and Käser, M.. (2012) Tuberkulose / HIV / AIDS - Prävention und Therapie in Ghana : Koinfektion als Herausforderung des Gesundheitssystems. Pharmazie in unserer Zeit, Vol. 41, issue 1. pp. 58-62. Khan, M. G. and Bhaskar, K. R. and Salam, M. A. and Akther, T. and Pluschke, G. and Mondal, D.. (2012) Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for detection of Leishmania DNA in buffy coat from visceral leishmaniasis patients. Parasites and Vectors, 5 (280). Käser, M. and Hauser, J. and Pluschke, G.. (2012) PCR typing of Mycobacterium ulcerans lineages based on large sequence polymorphisms. Journal of medical microbiology and diagnosis, Vol. S1 , 001. Pluschke, Gerd and Tamborrini, Marco. (2012) Development of a virosomal malaria vaccine candidate : from synthetic peptide design to clinical concept validation. Future virology, Vol. 7, H. 8. pp. 779-790. Ruf, M. T. and Schütte, D. and Chauffour, A. and Jarlier, V. and Ji, B. and Pluschke, G.. (2012) Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model. Antimicrobial agents and chemotherapy : AAC, Vol. 56, H. 2. pp. 687-696. Röltgen, K. and Assan-Ampah, K. and Danso, E. and Yeboah-Manu, D. and Pluschke, G.. (2012) Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 6, H. 11 , e1904. Röltgen, K. and Stinear, T. P. and Pluschke, G.. (2012) The genome, evolution and diversity of Mycobacterium ulcerans. Infection, genetics and evolution, Vol. 12, H. 3. pp. 522-529. Scherr, N. and Röltgen, K. and Witschel, M. and Pluschke, G.. (2012) Screening of antifungal azole drugs and agrochemicals with an adapted Alamar Blue-based assay demonstrates antibacterial activity of Croconazole against Mycobacterium ulcerans. Antimicrobial agents and chemotherapy, Vol. 56, H. 12. pp. 6410-6413. Shui, G. and Bendt, A. K. and Jappar, I. A. and Lim, H. M. and Laneelle, M. and Herve, M. and Via, L. E. and Chua, G. H. and Bratschi, M. W. and Rahim, S. Z. and Michelle, A. L. and Hwang, S. H. and Lee, J. S. and Eum, S. Y. and Kwak, H. K. and Daffe, M. and Dartois, V. and Michel, G. and Barry, Ceiii and Wenk, M. R.. (2012) Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice. EMBO molecular medicine, Vol. 4, H. 1. pp. 27-37. Yeboah-Manu, D. and Röltgen, K. and Opare, W. and Asan-Ampah, K. and Quenin-Fosu, K. and Asante-Poku, A. and Ampadu, E. and Fyfe, J. and Koram, K. and Ahorlu, C. and Pluschke, G.. (2012) Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 6, H. 1 , e1460. Zhang, Q. and Hunke, C. and Yau, Y. H. and Seow, V. and Lee, S. and Tanner, L. B. and Guan, X. L. and Wenk, M. R. and Fibriansah, G. and Chew, P. L. and Kukkaro, P. and Biukovic, G. and Shi, P. Y. and Shochat, S. G. and Gruber, G. and Lok, S. M.. (2012) The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation. Journal of biological chemistry, Vol. 287, H. 48. pp. 40525-40534. Cech, Patrick Georges and Aebi, Thomas and Abdallah, Mwanajaa Shomari and Mpina, Maxmillian and Machunda, Ester Barnabas and Westerfeld, Nicole and Stoffel, Sabine Alexandra and Zurbriggen, Rinaldo and Pluschke, Gerd and Tanner, Marcel and Daubenberger, Claudia and Genton, Blaise and Abdulla, Salim. (2011) Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine : randomized phase 1b trial in semi-immune adults & children. PLoS ONE, Vol. 6, H. 7 , e22273. Chauty, A. and Ardant, M. F. and Marsollier, L. and Pluschke, G. and Landier, J. and Adeye, A. and Goundoté, A. and Cottin, J. and Ladikpo, T. and Ruf, T. and Ji, B.. (2011) Oral treatment for Mycobacterium ulcerans infection : results from a pilot study in Benin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 52, H. 1. pp. 94-96. Gersbach, P. and Jantsch, A. and Feyen, F. and Scherr, N. and Dangy, J. P. and Pluschke, G. and Altmann, K. H.. (2011) A ring-closing metathesis (RCM)-based approach to mycolactones A/B. Chemistry : a European journal, Vol. 17, H. 46. pp. 13017-13031. Ghasparian, A. and Riedel, T. and Koomullil, J. and Moehle, K. and Gorba, C. and Svergun, D. I. and Perriman, A. W. and Mann, S. and Tamborrini, M. and Pluschke, G. and Robinson, J. A.. (2011) Engineered synthetic virus-like particles and their use in vaccine delivery. ChemBioChem : a European journal of chemical biology, Vol. 12, H. 1. pp. 100-109. Huber, C. A. and McOdimba, F. and Pflueger, V. and Daubenberger, C. A. and Revathi, G.. (2011) Characterisation of invasive and colonizing isolates of Streptococcus agalactiae in East African adults. Journal of clinical microbiology, Vol. 49, H. 10. pp. 3652-3655. Ruf, M. T. and Chauty, A. and Adeye, A. and Ardant, M. F. and Koussemou, H. and Johnson, R. C. and Pluschke, G.. (2011) Secondary Buruli ulcer skin lesions emerging several months after completion of chemotherapy : paradoxical reaction or evidence for immune protection? PLoS neglected tropical diseases, Vol. 5, H. 8 , e1252. Röltgen, K. and Pluschke, G.. (2011) SNP-Typisierung des Buruli-Ulkus-Erregers. Biospektrum, Vol. 17, H. 1. pp. 48-51. Tamborrini, M. and Bauer, M. and Bolz, M. and Maho, A. and Oberli, M. A. and Werz, D. B. and Schelling, E. and Zinsstag, J. and Seeberger, P. H. and Frey, J. and Pluschke, G.. (2011) Identification of an African bacillus anthracis lineage that lacks expression of the spore surface associated anthrose containing oligosaccharide. Journal of bacteriology : a publication of the American Society for Microbiology, Vol. 193, H. 14. pp. 3506-3511. Tamborrini, M. and Stoffel, S. A. and Westerfeld, N. and Amacker, M. and Theisen, M. and Zurbriggen, R. and Pluschke, G.. (2011) Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations. Malaria journal, Vol. 10 , 359. Tritten, Lucienne and Silbereisen, Angelika and Keiser, Jennifer. (2011) In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS neglected tropical diseases, Vol. 5, H. 12 , e1457. Yeboah-Manu D., and Asante-Poku A., and Asan-Ampah K., and Ampadu, E. D. and Pluschke, G.. (2011) Combining PCR with microscopy to reduce costs of laboratory diagnosis of Buruli ulcer. American journal of tropical medicine and hygiene, Vol. 85, H. 5. pp. 900-904. Yeboah-Manu D., and Asante-Poku A., and Bodmer, T. and Stucki, D. and Koram, K. and Bonsu, F. and Pluschke, G. and Gagneux, S.. (2011) Genotypic diversity and drug susceptibility patterns among M. tuberculosis complex isolates from South-Western Ghana. PLoS ONE, Vol. 6, H. 7 , e21906. Yeboah-Manu D., and Danso, E. and Ampah, K. and Asante-Poku A., and Nakobu, Z. and Pluschke, G.. (2011) Isolation of mycobacterium ulcerans from swab and fine-needle-aspiration specimens. Journal of clinical microbiology, Vol. 49, H. 5. pp. 1997-1999. Racloz, V. N. and Luiz, S. J.. (2010) The elusive meningococcal meningitis serogroup: a systematic review of serogroup B epidemiology. BMC infectious diseases, Vol. 10 , 175. Young, Barry P. and Shin, John J. H. and Orij, Rick and Chao, Jesse T. and Li, Shu Chen and Guan, Xue Li and Khong, Anthony and Jan, Eric and Wenk, Markus R. and Prinz, William A. and Smits, Gertien J. and Loewen, Christopher J. R.. (2010) Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. Science, Vol. 329, H. 5995. pp. 1085-1088. Braxmeier, S. and Hellmann, M. and Beck, A. and Umboock, A. and Pluschke, G. and Junghanss, T. and Weinlaeder, H.. (2009) Phase change material for thermotherapy of Buruli ulcer : modelling as an aid to implementation. Journal of medical engineering & technology : an international bi-monthly journal promoting the application of engineering and technology in medical research and clinical medicine, Vol. 33, H. 7. pp. 559-566. Huygen, K. and Adjei, O. and Affolabi, D. and Bretzel, G. and Demangel, C. and Fleischer, B. and Johnson, R. C. and Pedrosa, J. and Phanzu, D. M. and Phillips, R. O. and Pluschke, G. and Siegmund, V. and Singh, M. and van der Werf T. S., and Wansbrough-Jones M., and Portaels, F.. (2009) Buruli ulcer disease : prospects for a vaccine. Medical microbiology and immunology = Zeitschrift für medizinische Mikrobiologie und Immunologie, Vol. 198, H. 2. pp. 69-77. Junghanss, T. and Um Boock A., and Vogel, M. and Schütte, D. and Weinlaeder, H. and Pluschke, G.. (2009) Phase change material for thermotherapy of Buruli ulcer : a prospective observational single centre proof-of-principle trial. PLoS neglected tropical diseases, Vol. 3, H. 2 , e380. Käser, M. and Gutmann, O. and Hauser, J. and Stinear, T. and Cole, S. and Yeboah-Manu D., and Dernick, G. and Certa, U. and Pluschke, G.. (2009) Lack of insertional-deletional polymorphism in a collection of Mycobacterium ulcerans isolates from Ghanaian Buruli ulcer patients. Journal of clinical microbiology, Vol. 47, H. 11. pp. 3640-3646. Käser, M. and Hauser, J. and Pluschke, G.. (2009) Single nucleotide polymorphisms on the road to strain differentiation in Mycobacterium ulcerans. Journal of clinical microbiology, Vol. 47, H. 11. pp. 3647-3652. Käser, M. and Hauser, J. and Small, P. and Pluschke, G.. (2009) Large sequence polymorphisms unveil the phylogenetic relationship of environmental and pathogenic mycobacteria related to Mycobacterium ulcerans. Applied and environmental microbiology, Vol. 75, H. 17. pp. 5667-5675. Käser, M. and Ruf, M. T. and Hauser, J. and Marsollier, L. and Pluschke, G.. (2009) Optimized method for preparation of DNA from pathogenic and environmental mycobacteria. Applied and environmental microbiology, Vol. 75, H. 2. pp. 414-418. Leimkugel, J. and Racloz, L. and Da Silva J., and Pluschke, G.. (2009) Global review of meningococcal disease : a shifting etiology. Journal of bacteriology research, Vol. 1, H. 1. Qi, W. and Käser, M. and Röltgen, K. and Yeboah-Manu D., and Pluschke, G.. (2009) Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing. PLoS Pathogens, Vol. 5, H. 9 , e1000580. Schütte, D. and Um Boock A., and Pluschke, G.. (2009) Phagocytosis of Mycobacterium ulcerans in the course of rifampicin and streptomycin chemotherapy in Buruli ulcer lesions. British journal of dermatology, Vol. 160, H. 2. pp. 273-283. Schütte, Daniela and Pluschke, Gerd. (2009) Immunosuppression and treatment-associated inflammatory response in patients with Mycobacterium ulcerans infection (Buruli ulcer). Expert opinion on biological therapy, 9 (2). pp. 187-200. Tamborrini, M. and Mueller, M. S. and Stoffel, S. A. and Westerfeld, N. and Vogel, D. and Boato, F. and Zurbriggen, R. and Robinson, J. A. and Pluschke, G.. (2009) Design and pre-clinical profiling of a Plasmodium falciparum MSP-3 derived component for a multi-valent virosomal malaria vaccine. Malaria Journal, Vol. 8 , 314. Tamborrini, M. and Oberli, M. A. and Werz, D. B. and Schürch, N. and Frey, J. and Seeberger, P. H. and Pluschke, G.. (2009) Immuno-detection of anthrose containing tetrasaccharide in the exosporium of Bacillus anthracis and Bacillus cereus strains. Journal of applied microbiology, Vol. 106, H. 5. pp. 1618-1628. Treeck, M. and Tamborrini, M. and Daubenberger, C. A. and Gilberger, T. W. and Voss, Till S.. (2009) Caught in action : mechanistic insights into antibody-mediated inhibition of Plasmodium merozoite invasion. Trends in parasitology, Vol. 25, H. 11. pp. 494-497. NoBratschi, Martin W.. Epidemiology of Buruli ulcer in the Mapé Basin of Cameroon. 2015, Doctoral Thesis, University of Basel, Faculty of Science. Bolz, Miriam. Prospects for the development of a subunit vaccine against Mycobacterium ulcerans disease (Buruli ulcer). 2014, Doctoral Thesis, University of Basel, Faculty of Science. Dreyer, Anita. Characterization of novel surface proteins of "Plasmodium falciparum" and their assessment as molecular targets for a malaria subunit vaccine. 2012, Doctoral Thesis, University of Basel, Faculty of Science. Röltgen, Katharina. Development and application of new approaches to study the epidemiology of "mycobacterium ulcerans" disease (Buruli ulcer) in Ghana. 2012, Doctoral Thesis, University of Basel, Faculty of Science. Huber, Charlotte. Genetic diversity and immune evasion of bacterial pathogens. 2011, Doctoral Thesis, University of Basel, Faculty of Science. |