Items where Division is "05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Ehemalige Einheiten Pharmazie > Pharmakologie (Krähenbühl)"

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Bachmann, Fabio and Duthaler, Urs and Meyer Zu Schwabedissen, Henriette E. and Puchkov, Maxim and Huwyler, Jörg and Haschke, Manuel and Krähenbühl, Stephan. (2021) Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2. Clinical Pharmacology and Therapeutics, 109 (6). pp. 1505-1516.

Preisig, Daniel and Varum, Felipe and Bravo, Roberto and Hartig, Claudia and Spleiss, Johannes and Abbes, Sonia and Caobelli, Federico and Wild, Damian and Puchkov, Maxim and Huwyler, Jörg and Haschke, Manuel. (2021) Colonic delivery of metronidazole-loaded capsules for local treatment of bacterial infections: a clinical pharmacoscintigraphy study. European Journal of Pharmaceutics and Biopharmaceutics, 165. pp. 22-30.

Witzigmann, Dominik and Grossen, Philip and Quintavalle, Cristina and Lanzafame, Manuela and Schenk, Susanne H. and Tran, Xue-Ting and Englinger, Bernhard and Hauswirth, Patrick and Grünig, David and van Schoonhoven, Sushilla and Krähenbühl, Stephan and Terracciano, Luigi M. and Berger, Walter and Piscuoglio, Salvatore and Quagliata, Luca and Rommelaere, Jean and Nüesch, Jürg P. F. and Huwyler, Jörg. (2021) Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma. Journal of Controlled Release, 334. pp. 138-152.

Aubry, Emilie and Aeberhard, Carla and Bally, Lia and Nuoffer, Jean-Marc and Risch, Lorenz and Mühlebach, Stefan and Burgunder, Jean-Marc and Stanga, Zeno. (2018) Are patients affected by mitochondrial disorders at nutritional risk? Nutrition J (Burbank, Los Angeles County, Calif.), 47. pp. 56-62.

Bachmann, Fabio and Duthaler, Urs and Rudin, Deborah and Krähenbühl, Stephan and Haschke, Manuel. (2018) N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 120. pp. 172-180.

Berger, Benjamin and Bachmann, Fabio and Duthaler, Urs and Krähenbühl, Stephan and Haschke, Manuel. (2018) Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug. Frontiers in pharmacology, 9. p. 774.

Duthaler, Urs and Berger, Benjamin and Erb, Stefan and Battegay, Manuel and Letang, Emili and Gaugler, Stefan and Natamatungiro, Alex and Mnzava, Dorcas and Donzelli, Massimiliano and Krähenbühl, Stephan and Haschke, Manuel. (2018) Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions. Journal of Antimicrobial Chemotherapy, 73 (10). pp. 2729-2737.

Grünig, David and Duthaler, Urs and Krähenbühl, Stephan. (2018) Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells. Frontiers in pharmacology, 9. p. 257.

Grünig, David and Felser, Andrea and Duthaler, Urs and Bouitbir, Jamal and Krähenbühl, Stephan. (2018) Effect of the Catechol-O-Methyltransferase Inhibitors Tolcapone and Entacapone on Fatty Acid Metabolism in HepaRG Cells. Toxicological sciences, 164 (2). pp. 477-488.

Aeberhard, Carla and Steuer, Christian and Saxer, Christoph and Huber, Andreas and Stanga, Zeno and Mühlebach, Stefan. (2017) Physicochemical stability and compatibility testing of levetiracetam in all-in-one parenteral nutrition admixtures in daily practice. European journal of pharmaceutical sciences, 96. pp. 449-455.

Blaser, Lea and Hassna, Hala and Hofmann, Sarah and Holbro, Andreas and Haschke, Manuel and Rätz Bravo, Alexandra and Zeller, Andreas and Krähenbühl, Stephan and Taegtmeyer, Anne. (2017) Leucopenia associated with metamizole: a case-control study. Swiss medical weekly, 147. w14438.

Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234.

Brecht, Karin and Riebel, Virginie and Couttet, Philippe and Paech, Franziska and Wolf, Armin and Chibout, Salah-Dine and Pognan, Francois and Krähenbühl, Stephan and Uteng, Marianne. (2017) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicology in Vitro, 40. pp. 55-65.

Brueckner, David and Krähenbühl, Stephan and Zuber, Ulrich and Bonkat, Gernot and Braissant, Olivier. (2017) An alternative sterility assessment for parenteral drug products using isothermal microcalorimetry. Journal of Applied Microbiology, 123 (3). pp. 773-779.

Brueckner, David and Roesti, David and Zuber, Ulrich and Sacher, Meik and Duncan, Derek and Krähenbühl, Stephan and Braissant, Olivier. (2017) Tunable diode laser absorption spectroscopy as method of choice for non-invasive and automated detection of microbial growth in media fills. Talanta, 167. pp. 21-29.

Brueckner, David and Solokhina, Anna and Krähenbühl, Stephan and Braissant, Olivier. (2017) A combined application of tunable diode laser absorption spectroscopy and isothermal micro-calorimetry for calorespirometric analysis. Journal of Microbiological Methods, 139. pp. 210-214.

Drago, Sara and Imboden, Roger and Schlatter, Philipp and Buylaert, Mirabel and Krähenbühl, Stephan and Drewe, Juergen. (2017) Pharmacokinetics of Transdermal Etofenamate and Diclofenac in Healthy Volunteers. Basic and Clinical Pharmacology and Toxicology, 121 (5). pp. 423-429.

Duthaler, Urs and Berger, Benjamin and Erb, Stefan and Battegay, Manuel and Letang, Emilio and Gaugler, Stefan and Krähenbühl, Stephan and Haschke, Manuel. (2017) Automated high throughput analysis of antiretroviral drugs in dried blood spots. Journal of Mass Spectrometry, 52 (8). pp. 534-542.

Grünig, David and Felser, Andrea and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicology in Vitro, 42. pp. 337-347.

Haegler, Patrizia and Joerin, Lorenz and Krähenbühl, Stephan and Bouitbir, Jamal. (2017) Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents. Toxicological sciences, 157 (1). pp. 183-195.

Krähenbühl, Stephan. (2017) Importance of the skeletal muscle carnitine stores in fuel selection. The Journal of Physiology, 595 (17). pp. 5727-5728.

Krähenbühl, Stephan and Pichler, Werner J.. (2017) Medikamentöse Hepatopathien - Drug-induced liver injury. Therapeutische Umschau, 74 (3). pp. 123-130.

Luethi, Dino and Liechti, Matthias E. and Krähenbühl, Stephan. (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology, 387. pp. 57-66.

Paech, Franziska and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis. Frontiers in Pharmacology, 8. p. 367.

Paech, Franziska and Messner, Simon and Spickermann, Jochen and Wind, Mathias and Schmitt-Hoffmann, Anne-Hortense and Witschi, Anne Therese and Howell, Brett A. and Church, Rachel J. and Woodhead, Jeff and Engelhardt, Marc and Krähenbühl, Stephan and Maurer, Martina. (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Archives of Toxicology, 91 (11). pp. 3647-3662.

Parra-Guillen, Zinnia P. and Berger, Peter B. and Haschke, Manuel and Donzelli, Massimiliano and Winogradova, Daria and Pfister, Bogumila and Früh, Martin and Gillessen, Silke and Krähenbühl, Stephan and Kloft, Charlotte and Joerger, Markus. (2017) Role of Cytochrome P450 3A4 and 1A2 Phenotyping in Patients with Advanced Non-small-Cell Lung Cancer Receiving Erlotinib Treatment. Basic and Clinical Pharmacology and Toxicology, 121 (4). pp. 309-315.

Bonifacio, Annalisa and Mullen, Peter J. and Mityko, Ileana Scurtu and Navegantes, Luiz C. and Bouitbir, Jamal and Krähenbühl, Stephan. (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Archives of Toxicology, 90 (1). pp. 203-215.

Novakova, Katerina and Kummer, Oliver and Bouitbir, Jamal and Stoffel, Sonja D. and Hoerler-Koerner, Ulrike and Bodmer, Michael and Roberts, Paul and Urwyler, Albert and Ehrsam, Rolf and Krähenbühl, Stephan. (2016) Effect of l-carnitine supplementation on the body carnitine pool, skeletal muscle energy metabolism and physical performance in male vegetarians. European Journal of Nutrition, 55 (1). pp. 207-217.

Haegler, Patrizia and Grünig, David and Berger, Benjamin and Krähenbühl, Stephan and Bouitbir, Jamal. (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: a cell model for idiosyncratic toxicity. Toxicology, 336. pp. 48-58.

Roberts, Paul A. and Bouitbir, Jamal and Bonifacio, Annalisa and Singh, François and Kaufmann, Priska and Urwyler, Albert and Krähenbühl, Stephan. (2015) Contractile function and energy metabolism of skeletal muscle in rats with secondary carnitine deficiency. American Journal of Physiology. Endocrinology and Metabolism, 309 (3). E265-E274.

Bonifacio, Annalisa and Sanvee, Gerda M. and Bouitbir, Jamal and Krähenbühl, Stephan. (2015) The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity. Biochimica et biophysica acta. Molecular cell research, 1853 (8). pp. 1841-1849.

Liakoni, Evangelia and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2015) Hepatotoxicity of New Oral Anticoagulants (NOACs). Drug safety, 38 (8). pp. 711-720.

Ceschi, Alessandro and Heistermann, Elja and Gros, Sonja and Reichert, Cornelia and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2015) Acute sirolimus overdose: a multicenter case series. PLoS ONE, 10 (5). e0128033.

Seeland, Swen and Kettiger, Helene and Murphy, Mark and Treiber, Alexander and Giller, Jasmin and Kiss, Andrea and Sube, Romain and Krähenbühl, Stephan and Hafner, Mathias and Huwyler, Jörg. (2015) ATP-induced cellular stress and mitochondrial toxicity in cells expressing purinergic P2X7 receptor. Pharmacology Research & Perspecitves, 3 (2). e00123.

Sidharta, Patricia N. and Krähenbühl, Stephan and Dingemanse, Jasper. (2015) Pharmacokinetic and pharmacodynamic evaluation of macitentan , a novel endothelin receptor antagonist for the treatment of pulmonary arterial hypertension. Expert opinion on drug metabolism & toxicology, 11 (3). pp. 437-449.

Blaser, Lea S. and Tramonti, Alexandra and Egger, Pascal and Haschke, Manuel and Krähenbühl, Stephan and Rätz Bravo, Alexandra E.. (2015) Hematological safety of metamizole: retrospective analysis of WHO and Swiss spontaneous safety reports. European journal of clinical pharmacology, 71 (2). pp. 209-217.

Singh, François and Charles, Anne-Laure and Schlagowski, Anna-Isabel and Bouitbir, Jamal and Bonifacio, Annalisa and Piquard, François and Krähenbühl, Stephan and Geny, Bernard and Zoll, Joffrey. (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochimica et biophysica acta. Molecular cell research, 1853 (7). pp. 1574-1585.

Welzenbach, Karl and Mancuso, Riccardo V. and Krähenbühl, Stephan and Weitz-Schmidt, Gabriele. (2015) A novel multi-parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood. British Journal of Pharmacology, 172 (20). pp. 4875-4887.

Ceschi, Alessandro and Gregoriano, Claudia and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2014) Acute mycophenolate overdose : case series and systematic literature analysis. Expert opinion on drug safety, Vol. 13, H. 5. pp. 525-534.

Detampel, Pascal and Witzigmann, Dominik and Krähenbühl, Stephan and Huwyler, Jörg. (2014) Hepatocyte targeting using pegylated asialofetuin-conjugated liposomes. Journal of drug targeting, Vol. 22, No. 3. pp. 232-241.

Donzelli, Massimiliano and Derungs, Adrian and Serratore, Maria-Giovanna and Noppen, Christoph and Nezic, Lana and Krähenbühl, Stephan and Haschke, Manuel. (2014) The Basel Cocktail for Simultaneous Phenotyping of Human Cytochrome P450 Isoforms in Plasma, Saliva and Dried Blood Spots. Clinical pharmacokinetics, Vol. 53, H. 3. pp. 271-282.

Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. pp. 136-146.

Gregoriano, Claudia and Ceschi, Alessandro and Rauber-Lüthy, Christine and Kupferschmidt, Hugo and Banner, Nicholas R. and Krähenbühl, Stephan and Taegtmeyer, Anne B.. (2014) Acute thiopurine overdose : analysis of reports to a National Poison Centre 1995-2013. PLoS ONE, Vol. 9, H. 1 , e86390.

Liakoni, Evangelia and Rätz Bravo, Alexandra E. and Terracciano, Luigi and Heim, Markus and Krähenbühl, Stephan. (2014) Symptomatic hepatocellular liver injury with hyperbilirubinemia in two patients treated with rivaroxaban. JAMA internal medicine, Vol. 174, H. 10. pp. 1683-1686.

Morand, Réjane and Bouitbir, Jamal and Felser, Andrea and Hench, Jürgen and Handschin, Christoph and Frank, Stephan and Krähenbühl, Stephan. (2014) Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. European journal of nutrition, 53 (6). pp. 1313-1325.

Nezic, Lana and Derungs, Adrian and Bruggisser, Marcel and Tschudin-Sutter, Sarah and Krähenbühl, Stephan and Haschke, Manuel. (2014) Therapeutic drug monitoring of once daily aminoglycoside dosing : comparison of two methods and investigation of the optimal blood sampling strategy. European journal of clinical pharmacology, Vol. 70, H. 7. pp. 829-837.

Siller-Matula, J. M. and Trenk, D. and Krähenbühl, S. and Michelson, A. D. and Delle-Karth, G.. (2014) Clinical implications of drug-drug interactions with P2Y12 receptor inhibitors. Journal of thrombosis and haemostasis, Vol. 12, H. 1. pp. 2-13.

Taegtmeyer, Anne B. and Haschke, Manuel and Tchambaz, Lydia and Buylaert, Mirabel and Tschöpl, Martin and Beuers, Ulrich and Drewe, Jürgen and Krähenbühl, Stephan. (2014) A study of the relationship between serum bile acids and propranolol pharmacokinetics and pharmacodynamics in patients with liver cirrhosis and in healthy controls. PLoS ONE, Vol. 9, H. 6 , e97885.

Wuillemin, Natascha and Terracciano, Luigi and Beltraminelli, Helmut and Schlapbach, Christoph and Fontana, Stefano and Krähenbühl, Stephan and Pichler, Werner J. and Yerly, Daniel. (2014) T cells infiltrate the liver and kill hepatocytes in HLA-B(∗)57:01-associated floxacillin-induced liver injury. American journal of pathology, Vol. 184, no. 6. pp. 1677-1682.

Caduff Good, Angela and Nobel, Daniel and Krähenbühl, Stephan and Geisen, Christof and Henz, Samuel. (2013) Randomised trial of a clinical dosing algorithm to start anticoagulation with phenprocoumon. Swiss medical weekly, Vol. 143 , w13709.

Ceschi, A. and Rauber-Lüthy, C. and Kupferschmidt, H. and Banner, N. R. and Ansari, M. and Krähenbühl, S. and Taegtmeyer, A. B.. (2013) Acute Calcineurin Inhibitor Overdose: Analysis of Cases Reported to a National Poison Center Between 1995 and 2011. American journal of transplantation : official journal of the American Society of Transplant Surgeons (ASTS) and the American Society of Transplantation (AST), Vol. 13 , S. 786–795.

Franz, Carmen C. and Hildbrand, Carole and Born, Christa and Egger, Sabin and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2013) Dose adjustment in patients with liver cirrhosis : impact on adverse drug reactions and hospitalizations. European journal of clinical pharmacology, Vol. 69, H. 8. pp. 1565-1573.

Giger-Pabst, Urs and Lange, Jochen and Maurer, Christoph and Bucher, Carine and Schreiber, Vital and Schlumpf, Rolf and Kocher, Thomas and Schweizer, Walter and Krähenbühl, Stephan and Krähenbühl, Lukas. (2013) Short-term preoperative supplementation of an immunoenriched diet does not improve clinical outcome in well-nourished patients undergoing abdominal cancer surgery. Nutrition, Vol. 29, H. 5. pp. 724-729.

Haschke, Manuel and Schuster, Manfred and Poglitsch, Marko and Loibner, Hans and Salzberg, Marc and Bruggisser, Marcel and Penninger, Joseph and Krähenbühl, Stephan. (2013) Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects. Clinical pharmacokinetics, Vol. 52, H. 9. pp. 783-792.

Hirzel, E. and Lindinger, P. W. and Maseneni, S. and Giese, M. and Rhein, V. V. and Eckert, A. and Hoch, M. and Krahenbuhl, S. and Eberle, A. N.. (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. Journal of receptors and signal transduction, Vol. 33, H. 5. pp. 304-312.

Krähenbühl, Stephan. (2013) Leicht erhöhte Transaminasen. Therapeutische Umschau, Vol. 70, H. 5. pp. 284-288.

Maseneni, Swarna and Donzelli, Massimiliano and Brecht, Karin and Krähenbühl, Stephan. (2013) Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes. Toxicology, 308. pp. 11-19.

Morand, Réjane and Donzelli, Massimiliano and Haschke, Manuel and Krähenbühl, Stephan. (2013) Quantification of plasma carnitine and acylcarnitines by high-performance liquid chromatography-tandem mass spectrometry using online solid-phase extraction. Analytical and bioanalytical chemistry, Vol. 405, H. 27. pp. 8829-8836.

Mueller, F. and Büchel, B. and Köberle, D. and Schürch, S. and Pfister, B. and Krähenbühl, St and Froehlich, T. K. and Largiader, C. R. and Joerger, M.. (2013) Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study. Cancer chemotherapy and pharmacology, Vol. 71, H. 2. pp. 361-370.

Wuillemin, Natascha and Adam, Jacqueline and Fontana, Stefano and Krähenbühl, Stephan and Pichler, Werner J. and Yerly, Daniel. (2013) HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin. Journal of immunology, Vol. 190, H. 10. pp. 4956-4964.

Zahno, Anja and Bouitbir, Jamal and Maseneni, Swarma and Lindinger, Peter W. and Brecht, Karin and Krähenbühl, Stephan. (2013) Hepatocellular toxicity of clopidogrel: Mechanisms and risk factors. Free radical biology and medicine, 65. pp. 208-216.

Detampel, Pascal and Beck, Mareike and Krähenbühl, Stephan and Huwyler, Jörg. (2012) Drug interaction potential of resveratrol. Drug metabolism reviews, Vol. 44, H. 3. pp. 253-265.

Franz, Carmen C. and Egger, Sabin and Born, Christa and Rätz Bravo, Alexandra E. and Krähenbühl, Stephan. (2012) Potential drug-drug interactions and adverse drug reactions in patients with liver cirrhosis. European journal of clinical pharmacology, Vol. 68, H. 2. pp. 179-188.

Hardmeier, M. and Zimmermann, R. and Rüegg, S. and Pflüger, M. and Deuster, S. and Suter, K. and Donzelli, M. and Drewe, J. and Krähenbühl, S. and Fuhr, P. and Haschke, M.. (2012) Intranasal midazolam: pharmacokinetics and pharmacodynamics assessed by quantitative EEG in healthy volunteers. Clinical Pharmacology & Therapeutics, 91 (5). pp. 856-862.

Henkel, Verena and Casaulta, Flurina and Seemüller, Florian and Krähenbühl, Stephan and Obermeier, Michael and Hüsler, Jürg and Möller, Hans-Jürgen. (2012) Study design features affecting outcome in antidepressant trials. Journal of affective disorders, Vol. 141, H. 2-3. pp. 160-167.

Hysek, C. M. and Simmler, L. D. and Nicola, V. G. and Vischer, N. and Donzelli, M. and Krahenbuhl, S. and Grouzmann, E. and Huwyler, J. and Hoener, M. C. and Liechti, M. E.. (2012) Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. PLoS ONE, Vol. 7, H. 5 , e36476.

Joerger, M. and Ferreri, A. J. M. and Krähenbühl, S. and Schellens, J. H. M. and Cerny, Th and Zucca, E. and Huitema, A. D. R.. (2012) Dosing algorithm to target a predefined AUC in patients with primary central nervous system lymphoma receiving high dose methotrexate. British journal of clinical pharmacology, Vol. 73, H. 2. pp. 240-247.

Maseneni, Swarna and Donzelli, Massimiliano and Taegtmeyer, A. B. and Brecht, Karin and Krähenbühl, Stephan. (2012) Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites. Toxicology, 299 (2-3). pp. 139-145.

Morand, R. and Todesco, L. and Donzelli, M. and Fischer-Barnicol, D. and Mullen, P. J. and Krahenbuhl, S.. (2012) Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. Therapeutic drug monitoring, Vol. 34, H. 4. pp. 406-414.

Nezic, L. and Krähenbühl, S. and Rätz Bravo, A. E.. (2012) Diclofenac-induzierte Leberschäden = Diclofenac induced liver injuries. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine PRAXIS, Vol. 101, H. 6. pp. 371-379.

Pham, T. T. T. and See, H. H. and Morand, R. and Krahenbuhl, S. and Hauser, P. C.. (2012) Determination of free and total valproic acid in human plasma by capillary electrophoresis with contactless conductivity detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 907. pp. 74-78.

See, Hong Heng and Schmidt-Marzinkowski, Julia and Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2012) Determination of creatine and phosphocreatine in muscle biopsy samples by capillary electrophoresis with contactless conductivity detection. Analytica Chimica Acta, 727. pp. 78-82.

Derungs, Adrian and Schietzel, Simeon and Meyer, Markus R. and Maurer, Hans H. and Krähenbühl, Stephan and Liechti, Matthias E.. (2011) Sympathomimetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphthylpyrovalerone). Clinical toxicology, 49 (7). pp. 691-693.

Giger, U. and Ouaissi, M. and Schmitz, S.-F H. and Krähenbühl, S. and Krähenbühl, L.. (2011) Bile duct injury and use of cholangiography during laparoscopic cholecystectomy. British journal of surgery, Vol. 98, H. 3. pp. 391-396.

Halter, Joerg and Schüpbach, W. M. Michael and Casali, Carlo and Elhasid, Ronit and Fay, K. and Hammans, S. and Illa, I. and Kappeler, Liliane and Krähenbühl, Stephan and Lehmann, T. and Mandel, H. and Marti, Ramon and Mattle, Heinrich P. and Orchard, Kim and Savage, David and Sue, Carolyn M. and Valcarcel, David and Gratwohl, Alois and Hirano, M.. (2011) Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach. Bone marrow transplantation, 46 (3). pp. 330-337.

Hoch, Matthias and Hoever, Petra and Haschke, Manuel and Krähenbühl, Stephan and Dingemanse, Jasper. (2011) Food effect and biocomparison of two formulations of the dual orexin receptor antagonist almorexant in healthy male subjects. The journal of clinical pharmacology, Vol. 51, H. 7. pp. 1116-1121.

Kummer, Oliver and Hammann, Felix and Moser, Claudine and Schaller, Olivier and Drewe, Jürgen and Krähenbühl, Stephan. (2011) Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. European journal of clinical pharmacology, Vol. 67, H. 1. pp. 63-71.

Mullen, Peter J. and Zahno, Anja and Lindinger, Peter and Maseneni, Swarma and Felser, Andrea and Krähenbühl, Stephan and Brecht, Karin. (2011) Susceptibility to simvastatin-induced toxicity is partly determined by mitochondrial respiration and phosphorylation state of Akt. Biochimica et biophysica acta, Vol. 1813, H. 12. pp. 2079-2087.

Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2011) Capillary electrophoresis with contactless conductivity detection for the determination of carnitine and acylcarnitines in clinical samples. Journal of Chromatography B, 879 (13-14). pp. 921-926.

Pormsila, Worapan and Morand, Réjane and Krähenbühl, Stephan and Hauser, Peter C.. (2011) Quantification of plasma lactate concentrations using capillary electrophoresis with contactless conductivity detection. Electrophoresis, 32 (8). pp. 884-889.

Zahno, Anja and Brecht, Karin and Morand, Réjane and Maseneni, Swarna and Török, Michael and Lindinger, Peter W. and Krähenbühl, Stephan. (2011) The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells. Biochemical pharmacology, Vol. 81, Issue 3. pp. 432-441.

Bodmer, Michael and Meier, Christian and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R.. (2010) Long-term metformin use is associated with decreased risk of breast cancer. Diabetes care, Vol. 33, H. 6. pp. 1304-1308.

Brauchli, Yolanda B. and Wais, Thomas and Gratwohl, Alois and Heim, Dominik and Schipf, Alexander and Diebold, Joachim and Krähenbühl, Stephan. (2010) Fatal myocardial infarction during nilotinib treatment in a 60-year-old male patient. Acta oncologica, Vol. 49, no. 4. pp. 523-525.

Egger, S. S. and Meier, S. and Leu, C. and Christen, S. and Gratwohl, A. and Krahenbuhl, S. and Haschke, M.. (2010) Drug interactions and adverse events associated with antimycotic drugs used for invasive aspergillosis in hematopoietic SCT. Bone marrow transplantation, Vol. 45, H. 7. pp. 1197-1203.

Grisouard, Jean and Timper, Katharina and Radimerski, Tanja M. and Frey, Daniel M. and Peterli, Ralph and Kola, Blerina and Korbonits, Marta and Herrmann, Paul and Krahenbuhl, Stephan and Zulewski, Henryk and Keller, Ulrich and Muller, Beat and Christ-Crain, Mirjam. (2010) Mechanisms of metformin action on glucose transport and metabolism in human adipocytes. Biochemical Pharmacology, 80 (11). pp. 1736-1745.

Haschke, Manuel and Suter, Katja and Hofmann, Sarah and Witschi, Robert and Fröhlich, Johannes and Imanidis, Georgios and Drewe, Jürgen and Briellmann, Thomas A. and Dussy, Franz E. and Krähenbühl, Stephan and Surber, Christian. (2010) Pharmacokinetics and pharmacodynamics of nasally delivered midazolam. British journal of clinical pharmacology, Vol. 69, H. 6. pp. 607-616.

Joerger, M. and Huitema, A. D. R. and Krähenbühl, S. and Schellens, J. H. M. and Cerny, T. and Reni, M. and Zucca, E. and Cavalli, F. and Ferreri, A. J. M.. (2010) Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma : a pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial. British journal of cancer, Vol. 102, H. 4. pp. 673-677.

Mullen, Peter James and Lüscher, Barbara and Scharnagl, Hubert and Krähenbühl, Stephan and Brecht, Karin. (2010) Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy. Biochemical pharmacology, 79 (8). pp. 1200-1209.

Popov, Yury and Sverdlov, Deanna Y. and Bhaskar, K. Ramakrishnan and Sharma, Anisha K. and Millonig, Gunda and Patsenker, Eleonora and Krahenbuhl, Stephan and Krahenbuhl, Lukas and Schuppan, Detlef. (2010) Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis. American journal of physiology. Gastrointestinal and liver physiology, Vol. 298, H. 3 , G323-334.

Pormsila, W. and Krähenbühl, S. and Hauser, P. C.. (2010) Determination of carnitine in food and food supplements by capillary electrophoresis with contactless conductivity detection. Electrophoresis, Vol. 31. pp. 2186-2191.

Sawatzki, M. and Kummer, O. and Krähenbühl, S. and Siegemund, M.. (2010) 35-jährige Patientin mit generalisiertem Krampfanfall und nicht-kardiogenem Lungenödem nach Intoxikation. Internist, 51 (4). pp. 528-532.

Schürch, Regula and Todesco, Liliane and Novakova, Katarina and Mevissen, Meike and Stieger, Bruno and Krähenbühl, Stephan. (2010) The plasma carnitine concentration regulates renal OCTN2 expression and carnitine transport in rats. European journal of pharmacology, Vol. 635, H. 1-3. pp. 171-176.

Zahno, Anja and Brecht, Karin and Bodmer, Michael and Bur, Daniel and Tsakiris, Dimitrios A. and Krähenbühl, Stephan. (2010) Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. British journal of pharmacology, 161 (2). pp. 393-404.

Bodmer, Michael and Brauchli, Yolanda B. and Krähenbühl, Stephan and Jick, Susan S. and Meier, Christoph R.. (2009) Statin use and risk of gallstone disease followed by cholecystectomy. JAMA : the journal of the American Medical Association, Vol. 302, H. 18. pp. 2001-2007.

Giger, U. and Wente, M. N. and Büchler, M. W. and Krähenbühl, S. and Lerut, J. and Krähenbühl, L.. (2009) Endoscopic retroperitoneal neurectomy for chronic pain after groin surgery. British journal of surgery, Vol. 96, H. 9. pp. 1076-1081.

Kummer, Oliver and Haschke, Manuel and Hammann, Felix and Bodmer, Michael and Bruderer, Shirin and Regnault, Yann and Dingemanse, Jasper and Krähenbühl, Stephan. (2009) Comparison of the dissolution and pharmacokinetic profiles of two galenical formulations of the endothelin receptor antagonist macitentan. European journal of pharmaceutical sciences, Vol. 38, H. 4. pp. 384-388.

Pormsila, W. and Krahenbuhl, S. and Hauser, P. C.. (2009) Capillary electrophoresis with contactless conductivity detection for uric acid determination in biological fluids. Analytica Chimica Acta, Vol. 636, pp. 224-228.

Rätz Bravo, Alexandra E. and Hofer, Silvia and Krähenbühl, Stephan and Ludwig, Christian. (2009) Fatal drug-drug interaction of brivudine and capecitabine. Acta oncologica, Vol. 48, no. 4. pp. 631-633.

Schlatter, Chantal and Egger, Sabin S. and Tchambaz, Lydia and Krähenbühl, Stephan. (2009) Pharmacokinetic changes of psychotropic drugs in patients with liver disease : implications for dose adaptation. Drug safety, Vol. 32, no. 7. pp. 561-578.

Sidharta, P. N. and Rave, K. and Heinemann, L. and Chiossi, E. and Krahenbuhl, S. and Dingemanse, J.. (2009) Effect of the urotensin-II receptor antagonist palosuran on secretion of and sensitivity to insulin in patients with Type 2 diabetes mellitus. British journal of clinical pharmacology, Vol. 68, no. 4. pp. 502-510.

Todesco, Liliane and Bodmer, Michael and Vonwil, Karin and Häussinger, Daniel and Krähenbühl, Stephan. (2009) Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2. Chemico-Biological Interactions , 180 (3). pp. 472-477.

Jauch , K. W. and Schregel , W. and Stanga , Z. and Bischoff , S. C. and Brass , P. and Hartl, W. and Mühlebach , Stefan F. and Pscheidl , E. and Thul, P. and Volk , O.. (2008) Technik und Probleme der Zugänge in der parenteralen Ernährung. In: DGEM-Leitlinien Enterale und Parenterale Ernährung. Kurzfassung. Stuttgart, pp. 20-24.

Mühlebach , Stefan F. and Stanga, Z. and Franken, C.. (2008) Praktische Handhabung von All-in-one (AIO)-Mischungen. In: DGEM-Leitlinien Enterale und Parenterale Ernährung. Stuttgart, pp. 25-28.

Waldhauser, Katri M. and Brecht, Karin and Hebeisen, S. and Ha, H. R. and Konrad, D. and Bur, Daniel and Krähenbühl, Stephan. (2008) Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues. British journal of pharmacology, 155 (4). pp. 585-595.

Fusch C., Bauer K. and Böhles H. -J., Jochum F. and Koletzko B., Krawinkel M. and Krohn, K. and Mühlebach, S.. (2007) Leitlinie Parentale Ernährung der DGEM: Guideline for parenteral nutrition of the DGEM. Part 13: Neonatology/pediatrics. Aktuelle Ernährungsmedizin, 32 (Suppl 1). pp. 72-S88.

Jauch , K. W. and Schregel, W. and Stanga, Zeno and Bischoff, Stephan C. and Braß , P. and Hartl, W. and Mühlebach , Stefan F. and Pscheidl, E. and Thul, P. and Volk, O.. (2007) Leitlinie Parentale Ernährung der DGEM: 9 Technik und Probleme der Zugänge in der parentalen Ernährung ; Guideline for parenteral nutrition of the DGEM. Part 9: Technique and problems of access in parenteral nutrition. Aktuelle Ernährungsmedizin, 32 (Suppl 1). S41-S53.

Mühlebach, S.. (2007) Incompatibility reactions in drug therapy - preventable medication errors. European Journal of Hospital Pharmacy, 13 (2). pp. 30-31.

Mühlebach , Stefan F. and Franken , C. and Stanga, Zeno. (2007) Leitlinie Parenterale Ernährung der DGEM. 10 Praktische Handhabung von AIO-Mischungen ; Guideline for parenteral nutrition of the DGEM. Part 10: Practical use of all-in-one mixtures. Aktuelle Ernährungsmedizin, 32 (Suppl 1). S54-S59.

Kaufmann, Priska and Török, Michael and Zahno, Anja and Waldhauser, Katri and Brecht, Karin and Krähenbühl, Stephan. (2006) Toxicity of statins on rat skeletal muscle mitochondria. Cellular and Molecular Life Sciences, 63 (19-20). pp. 2415-2425.

Mühlebach, Stefan F. and Karlaganis, G. and Honegger, U. E.. (2006) Kinetic assessment of persistent halogenated xenobiotics in cell culture models: comparison of mono- and poly-halogenated compounds. Chemosphere, 62 (11). pp. 1838-1845.

Waldhauser, Katri and Török, Michael and Ha, Huy-Riem and Thomet, Urs and Konrad, Daniel and Brecht, Karin and Follath, Ferenc and Krahenbühl, Stephan. (2006) Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives. Journal of pharmacology and experimental therapeutics, 319 (3). pp. 1413-1423.

Mühlebach , Stefan F. and Deuster , S.. (2005) Chemisch-physikalische Inkompatibilitäten parenterale verabreichter Arzneimittel (Zumischen von Arzneimitteln zu Infusionslösungen). In: Grundlagen der Arzneimitteltherapie. Basel, pp. 234-239.

Barnett , M. I. and Pertkiewicz , M. and Cosslett , A. G. and Mühlebach , Stefan and Dudrick , S. J.. (2004) Parenteral nutrition admixtures. 6.3.1. How to prepare parenteral nutrition (PN) admixtures. In: Basics in Clinical Nutrition. Prague, pp. 260-264.

Mühlebach, Stefan. (2004) Drugs and nutritional admixtures. In: Basics in Clinical Nutrition. Prague, pp. 269-275.

Pertkiewicz, M. and Cosslett , A. G. and Mühlebach , Stefan F. and Dudrick, S. J.. (2004) Stability of parenteral nutrition admixtures. In: Basics in Clinical Nutrition. Prague, pp. 264-269.

Hämmerli, M. and Mühlebach , Stefan F.. (2002) Ist der Einsatz von Methylphenidat mit einem kardiovaskulären Risiko verbunden? Paediatrica, 13 (1). pp. 30-33.

Mühlebach , Stefan F.. (2002) Heimparenterale Ernährung: Internationale Entwicklungen und Langzeiterfahrungen aus der Schweiz Home Parenteral Nutrition (HPN)International Background and Long-Term Experience in SwitzerlandHome parenteral nutrition (HPN) international background and long-term experience in Switzerland. Aktuelle Ernährungsmedizin, 27 (6). pp. 425-430.

Mühlebach , Stefan F. and Fasolini, Fabrizio. (2000) The nutrition support team at the Kantonspital Aarau (KSA): Functions, development, and experiences over a ten years period. Viszeralchirurgie, 35 (1). pp. 69-71.

Steger, P. J. and Mühlebach, Stefan F.. (2000) Lipid peroxidation of intravenous lipid emulsions and all-in-one admixtures in total parenteral nutrition bags: the influence of trace elements. JPEN, Journal of parenteral and enteral nutrition, 24 (1). pp. 37-41.

Dörje, Frank and Radziwill, Roland and Mühlebach, Stefan. (1998) Ernährungstherapie. Deutsche Apotheker Zeitung, 138 (36). pp. 37-41.

Steger , Patrick and Mühlebach , Stefan. (1997) Lipidperoxidation in intravenösen Fettemulsionen: Detektionsmethoden und Einflussfaktoren. In: Fett in Nahrung und Ernährung. Stuttgart, pp. 264-268.

Rötheli-Simmen, B. and Martinelli, E. and Mühlebach, S.. (1996) Formulation of a stable calcium gluconate gel for topical treatment of hydrofluoric acid burns. European Journal of Hospital Pharmacy, 2 (4). pp. 176-180.

Martinelli, Enea and Mühlebach, Stefan. (1995) Kunststoffumbeutel als Lichtschutz für Infusionen. Ergebnisse einer praxisnahen Untersuchung mit Vitamin K1 als Testsubstanz. Krankenhauspharmazie, 16 (7). pp. 286-289.

Martinelli, E. and Mühlebach, S. and Vozeh, S.. (1994) Phenytoin kinetics in the elderly: hospitalized patients treated with an i.v. loading regimen followed by individual dosage based on Bayesian forecasting calculations. In: Drug treatment in the elderly. Proceedings of the conference held in Leysin, Switzerland, March 10-12, 1994. pp. 129-134.

Jondorf, W. R. and Wyss, P. A. and Mühlebach, S. and Bickel, M. H.. (1983) Disposition of 2,2',4,4',5,5'-hexachlorobiphenyl (6-CB) in rats with decreasing adipose tissue mass. II. Effects of restricting food intake before and after 6-CB administration. Drug Metabolism and Disposition, 11 (6). pp. 597-601.

Wyss, P. A. and Mühlebach, S. and Bickel, M. H.. (1982) Pharmacokinetics of 2,2',4,4',5,5'-hexachlorobiphenyl (6-CB) in rats with decreasing adipose tissue mass. I. Effects of restricting food intake two weeks after administration of 6-CB. Drug Metabolism and Disposition, 10 (6). pp. 657-661.

No

Donzelli, Massimiliano. Development, validation and application of the Basel phenotyping cocktail. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Hägler, Patrizia. Establishment of "in vitro" and "in vivo" models with underlying mitochondrial dysfunction for testing idiosyncratic drug toxicity. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Czaja, Karol Gustaw. Killer cell immunoglobulin-like receptors and their ligands : assessment of potential diagnostic and immunotherapeutic value. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Stegmann, Danielle Alexandra. Gene expression analyses on skin lesions from patients with familial adenomatous polyposis. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Hysek, Cédric Marc. The role of norephinephrine in the pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Bourqui, Réjane Morand. Carnitine : analytical and physiological aspects. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Kwan, Hiu Ying. Enantioselective capillary electrophoresis : fundamental aspects and application to the "in vitro" assessment of CYP3A4 mediated ketamine N-demethylation. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Maseneni, Swarna. Myelotoxicity of thienopyridines. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Link, Bettina. "In-vivo" phenotyping of CYP3A using midazolam as probe drug : development of novel approaches based on highly sensitive LC-MS/MS methods. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Mullen, Peter James. Molecular mechanisms of statin-induced myotoxicity. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Zahno, Anja-Christina. Drug interactions and hepatotoxicity of clopidogrel. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Andrée, Colette Marie. Development and validation of tools for the asssessment of the burden and disease-management of headache disorders in Europe. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Schlatter-Häner, Chantal. Dose adaptation of drugs in patients with liver disease. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Knapp, Andrea Caroline. Characterization of "in vitro" and "in vivo" models for the investigation of hepatotoxicity. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Waldhauser, Katri Maria. Mitochondrial toxicity of drugs. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Egger, Sabin Séverine. Potential risk factors for adverse drug reactions in elderly patients : contribution to safer drug prescribing. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Allemann, Sabin Liliane. Evidence based diabetology : strategies to prevent macrovascular disease and to reduce mortality. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Indermitte, Jörg Lorenz. Potential drug interactions : exposure and management in hospital and ambulatory settings. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Noyer, Mathieu. Murine c-erbB2: an oncogene that could be a target for vaccination therapy? : and the effect of HER2/c-erbB2/NeuT expression on cell signaling and milk protein formation in mouse mammary epithelial cells. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Botomino, Andrea. Diabetes screening and health promotion : evaluation of a pharmacy based campaign and of related activities. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Kaufmann, Priska M.. A small dose of toxicology : role of mitochondrial dysfunction in hepatic and skeletal muscle toxicity. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Lüde, Saskia. Hepatotoxicity of the phytomedicines Kava Kava and Cimicifuga Racemosa. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Vernez, Laurence. Analysis of carnitine and acylcaritines in biological fluids and application to a clinical study. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Wirz, Adrian. "In vitro" study of the mode of action of antidepressants in cell culture models : comparison of the effects of "Hypericum perforatum L." extracts and classical synthetic compounds on the [beta]-adrenergic signal pathway. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Mühlebach , Stefan F.. (2004) Mangelernährung und ihre Folgen: Die Bedeutung des klinlischen Ernährungsteams. Schweizer Zeitschrift für Ernährungsmedizin, 4. pp. 42-44.

Reinke, Claudia and Mühlebach, Stefan and Beutler, Marianne. (2000) Cytochrome und Arzneimittel. Schweizerische Apotheker-Zeitung, 138 (23). pp. 769-771.

Gabriel, Cornelia and Mühlebach, Stefan. (1999) Melatonin - Kritischer Umgang mit einer problematischen Substanz. Schweizerische Apotheker-Zeitung, 137 (3). pp. 72-76.

Mühlebach, S.. (1991) Sterilization in the pharmaceutic industry and hospitals. Pharmazeutische Zeitung, 136 (13). pp. 24-26.