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Items where Division is "05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Molekulare Pharmazie (Ricklin)"

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Jump to: 12 January 2019 | 2019 | 2018 | 2017 | 2016 | 2015
Number of items at this level: 36.

12 January 2019

Epper, Bettina. (12 January 2019) Dossier "Wirkstoffe" - Vom Molekül zum Medikament. Drogistenstern, (12/19-1/20). pp. 6-16.

2019

Pouw, Richard B. and Brouwer, Mieke C. and de Gast, Marlon and van Beek, Anna E. and van den Heuvel, Lambertus P. and Schmidt, Christoph Q. and van der Ende, Arie and Sánchez-Corral, Pilar and Kuijpers, Taco W. and Wouters, Diana. (2019) Potentiation of complement regulator factor H protects human endothelial cells from complement attack in aHUS sera. Blood advances, 3 (4). pp. 621-632.

2018

Devaurs, Didier and Papanastasiou, Malvina and Antunes, Dinler A. and Abella, Jayvee R. and Moll, Mark and Ricklin, Daniel and Lambris, John D. and Kavraki, Lydia E.. (2018) Native State of Complement Protein C3d Analysed via Hydrogen Exchange and Conformational Sampling. International journal of computational biology and drug design, 11 (1-2). pp. 90-113.

Harris, Claire L. and Pouw, Richard B. and Kavanagh, David and Sun, Ruyue and Ricklin, Daniel. (2018) Developments in anti-complement therapy; from disease to clinical trial. Molecular immunology, 102. pp. 89-119.

Pouw, Richard B. and Brouwer, Mieke C. and van Beek, Anna E. and Józsi, Mihály and Wouters, Diana and Kuijpers, Taco W.. (2018) Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4. Frontiers in Immunology, 9. p. 729.

Pouw, Richard B. and Gómez Delgado, Irene and López Lera, Alberto and Rodríguez de Córdoba, Santiago and Wouters, Diana and Kuijpers, Taco W. and Sánchez-Corral, Pilar. (2018) High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B. Frontiers in Immunology, 9. p. 848.

Reis, Edimara S. and Mastellos, Dimitrios C. and Ricklin, Daniel and Mantovani, Alberto and Lambris, John D.. (2018) Complement in cancer: untangling an intricate relationship. Nature reviews. Immunology, 18 (1). pp. 5-18.

Ricklin, Daniel and Mastellos, Dimitrios C. and Reis, Edimara S. and Lambris, John D.. (2018) The renaissance of complement therapeutics. Nature Reviews Nephrology , 14 (1). pp. 26-47.

Sánchez-Corral, Pilar and Pouw, Richard B. and López-Trascasa, Margarita and Józsi, Mihály. (2018) Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family. Frontiers in immunology, 9. p. 1607.

Yuan, Xiaopeng and Yang, Mingjuan and Chen, Xiang and Zhang, Xuhua and Sukhadia, Shrey and Musolino, Najia and Bao, Huijing and Chen, Tingtao and Xu, Chen and Wang, Qirui and Santoro, Stephen and Ricklin, Daniel and Hu, Jia and Lin, Ruihe and Yang, Wei and Li, Zhijun and Qin, Weijun and Zhao, Aizhi and Scholler, Nathalie and Coukos, George. (2018) Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy. Cancer immunology, immunotherapy : CII, 67 (2). pp. 329-339.

2017

Blatt, Adam Z. and Saggu, Gurpanna and Cortes, Claudio and Herbert, Andrew P. and Kavanagh, David and Ricklin, Daniel and Lambris, John D. and Ferreira, Viviana P.. (2017) Factor H C-Terminal Domains Are Critical for Regulation of Platelet/Granulocyte Aggregate Formation. Frontiers in Immunology, 8. p. 1586.

Devaurs, Didier and Antunes, Dinler A. and Papanastasiou, Malvina and Moll, Mark and Ricklin, Daniel and Lambris, John D. and Kavraki, Lydia E.. (2017) Coarse-Grained Conformational Sampling of Protein Structure Improves the Fit to Experimental Hydrogen-Exchange Data. Frontiers in Molecular Biosciences, 4. p. 13.

Flesch, Daniel and Cheung, Sun-Yee and Schmidt, Jurema and Gabler, Matthias and Heitel, Pascal and Kramer, Jan and Kaiser, Astrid and Hartmann, Markus and Lindner, Mara and Lüddens-Dämgen, Kerstin and Heering, Jan and Lamers, Christina and Lüddens, Hartmut and Wurglics, Mario and Proschak, Ewgenij and Schubert-Zsilavecz, Manfred and Merk, Daniel. (2017) Nonacidic Farnesoid X Receptor Modulators. Journal of Medicinal Chemistry, 60 (16). pp. 7199-7205.

Hajishengallis, George and Reis, Edimara S. and Mastellos, Dimitrios C. and Ricklin, Daniel and Lambris, John D.. (2017) Novel mechanisms and functions of complement. Nature Immunology, 18 (12). pp. 1288-1298.

Harder, Markus J. and Kuhn, Nadine and Schrezenmeier, Hubert and Höchsmann, Britta and von Zabern, Inge and Weinstock, Christof and Simmet, Thomas and Ricklin, Daniel and Lambris, John D. and Skerra, Arne and Anliker, Markus and Schmidt, Christoph Q.. (2017) Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation. Blood, 129 (8). pp. 970-980.

Hevey, Rachel and Ling, Chang-Chun. (2017) Studies on the 6-homologation of β-D-idopyranosides. Carbohydrate Research, 445. pp. 65-74.

Mastellos, Dimitrios C. and Reis, Edimara S. and Ricklin, Daniel and Smith, Richard J. and Lambris, John D.. (2017) Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery. Trends in Immunology, 38 (6). pp. 383-394.

Papanastasiou, Malvina and Koutsogiannaki, Sophia and Sarigiannis, Yiannis and Geisbrecht, Brian V. and Ricklin, Daniel and Lambris, John D.. (2017) Structural Implications for the Formation and Function of the Complement Effector Protein iC3b. Journal of immunology (Baltimore, Md. : 1950), 198 (8). pp. 3326-3335.

Primikyri, Alexandra and Papanastasiou, Malvina and Sarigiannis, Yiannis and Koutsogiannaki, Sophia and Reis, Edimara S. and Tuplano, Joel V. and Resuello, Ranillo R. G. and Nilsson, Bo and Ricklin, Daniel and Lambris, John D.. (2017) Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS. Journal of Chromatography B, 1041-1042. pp. 19-26.

Ricklin, Daniel and Barratt-Due, Andreas and Mollnes, Tom Eirik. (2017) Complement in clinical medicine: Clinical trials, case reports and therapy monitoring. Molecular Immunology, 89. pp. 10-21.

Wang, HongBin and Ricklin, Daniel and Lambris, John D.. (2017) Complement-activation fragment C4a mediates effector functions by binding as untethered agonist to protease-activated receptors 1 and 4. Proceedings of the National Academy of Sciences of the United States of America, 114 (41). pp. 10948-10953.

Xue, Xiaoguang and Wu, Jin and Ricklin, Daniel and Forneris, Federico and Di Crescenzio, Patrizia and Schmidt, Christoph Q. and Granneman, Joke and Sharp, Thomas H. and Lambris, John D. and Gros, Piet. (2017) Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses. Nature Structural and Molecular Biology, 24. pp. 643-651.

Yuan, Xiaopeng and Yang, Mingjuan and Chen, Xiang and Zhang, Xuhua and Sukhadia, Shrey and Musolino, Najia and Bao, Huijing and Chen, Tingtao and Xu, Chen and Wang, Qirui and Santoro, Stephen and Ricklin, Daniel and Hu, Jia and Lin, Ruihe and Yang, Wei and Li, Zhijun and Qin, Weijun and Zhao, Aizhi. (2017) Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy. Cancer Immunology, Immunotherapy, 66 (3). pp. 367-378.

Zhang, Pengfei and Hevey, Rachel and Ling, Chang-Chun. (2017) Total Synthesis of β-d-ido-Heptopyranosides Related to Capsular Polysaccharides of Campylobacter jejuni HS:4. The Journal of Organic Chemistry, 82 (18). pp. 9662-9674.

van Beek, Anna E. and Pouw, Richard B. and Brouwer, Mieke C. and van Mierlo, Gerard and Geissler, Judy and Ooijevaar-de Heer, Pleuni and de Boer, Martin and van Leeuwen, Karin and Rispens, Theo and Wouters, Diana and Kuijpers, Taco W.. (2017) Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma. Frontiers in Immunology, 8. p. 1328.

2016

Blöcher, René and Lamers, Christina and Wittmann, Sandra K. and Merk, Daniel and Hartmann, Markus and Weizel, Lilia and Diehl, Olaf and Brüggerhoff, Astrid and Boß, Marcel and Kaiser, Astrid and Schader, Tim and Göbel, Tamara and Grundmann, Manuel and Angioni, Carlo and Heering, Jan and Geisslinger, Gerd and Wurglics, Mario and Kostenis, Evi and Brüne, Bernhard and Steinhilber, Dieter and Schubert-Zsilavecz, Manfred and Kahnt, Astrid S. and Proschak, Ewgenij. (2016) N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators. Journal of medicinal chemistry, 59 (1). pp. 61-81.

Lamers, Christina and Merk, Daniel and Gabler, Matthias and Flesch, Daniel and Kaiser, Astrid and Schubert-Zsilavecz, Manfred. (2016) SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound. Future medicinal chemistry, 8 (2). pp. 133-148.

Pouw, Richard B. and Brouwer, Mieke C. and Geissler, Judy and van Herpen, Laurens V. and Zeerleder, Sacha S. and Wuillemin, Walter A. and Wouters, Diana and Kuijpers, Taco W.. (2016) Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3. PLoS ONE, 11 (3). e0152164.

Ricklin, Daniel and Lambris, John D.. (2016) Preformed mediators of defense-Gatekeepers enter the spotlight. Immunological Reviews, 274 (1). pp. 5-8.

Ricklin, Daniel and Reis, Edimara S. and Mastellos, Dimitrios C. and Gros, Piet and Lambris, John D.. (2016) Complement component C3 - The "Swiss Army Knife" of innate immunity and host defense. Immunological Reviews , 274 (1). pp. 33-58.

Schmidt, Christoph Q. and Lambris, John D. and Ricklin, Daniel. (2016) Protection of host cells by complement regulators. Immunological Reviews, 274 (1). pp. 152-171.

Schäfer, Nicole and Grosche, Antje and Reinders, Joerg and Hauck, Stefanie M. and Pouw, Richard B. and Kuijpers, Taco W. and Wouters, Diana and Ehrenstein, Boris and Enzmann, Volker and Zipfel, Peter F. and Skerka, Christine and Pauly, Diana. (2016) Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases. Frontiers in immunology, 7. p. 542.

2015

Flesch, Daniel and Ness, Julia and Lamers, Christina and Dehm, Friederike and Popella, Sven and Steri, Ramona and Ogorek, Isabella and Hieke, Martina and Dannhardt, Gerd and Werz, Oliver and Weggen, Sascha and Schubert-Zsilavecz, Manfred. (2015) SAR-studies of γ-secretase modulators with PPARγ-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease. Bioorganic and Medicinal Chemistry Letters, 25 (4). pp. 841-846.

Keizer, Mischa P. and Pouw, Richard B. and Kamp, Angela M. and Patiwael, Sanne and Marsman, Gerben and Hart, Margreet H. and Zeerleder, Sacha and Kuijpers, Taco W. and Wouters, Diana. (2015) TFPI inhibits lectin pathway of complement activation by direct interaction with MASP-2. European journal of immunology, 45 (2). pp. 544-550.

Merk, Daniel and Lamers, Christina and Weber, Julia and Flesch, Daniel and Gabler, Matthias and Proschak, Ewgenij and Schubert-Zsilavecz, Manfred. (2015) Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands. Bioorganic & medicinal chemistry, 23 (3). pp. 499-514.

Pouw, R. B. and Vredevoogd, D. W. and Kuijpers, T. W. and Wouters, D.. (2015) Of mice and men: The factor H protein family and complement regulation. Molecular immunology, 67 (1). pp. 12-20.

This list was generated on Fri May 29 03:58:45 2020 CEST.