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Items where Author is "Yeo, T."

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Number of items: 10.

Article

Lowe, M. A. and Cardenas, A. and Valentin, J. P. and Zhu, Z. and Abendroth, J. and Castro, J. L. and Class, R. and Delaunois, A. and Fleurance, R. and Gerets, H. and Gryshkova, V. and King, L. and Lorimer, D. D. and MacCoss, M. and Rowley, J. H. and Rosseels, M. L. and Royer, L. and Taylor, R. D. and Wong, M. and Zaccheo, O. and Chavan, V. P. and Ghule, G. A. and Tapkir, B. K. and Burrows, J. N. and Duffey, M. and Rottmann, M. and Wittlin, S. and Angulo-Barturen, I. and Jiménez-Díaz, M. B. and Striepen, J. and Fairhurst, K. J. and Yeo, T. and Fidock, D. A. and Cowman, A. F. and Favuzza, P. and Crespo-Fernandez, B. and Gamo, F. J. and Goldberg, D. E. and Soldati-Favre, D. and Laleu, B. and de Haro, T.. (2022) Discovery and characterization of potent, efficacious, orally available antimalarial plasmepsin X inhibitors and preclinical safety assessment of UCB7362. Journal of medicinal chemistry, 65 (20). pp. 14121-14143.

Laleu, B. and Rubiano, K. and Yeo, T. and Hallyburton, I. and Anderson, M. and Crespo-Fernandez, B. and Gamo, F. J. and Antonova-Koch, Y. and Orjuela-Sanchez, P. and Wittlin, S. and Jana, G. P. and Maity, B. C. and Chenu, E. and Duffy, J. and Sjo, P. and Waterson, D. and Winzeler, E. and Guantai, E. and Fidock, D. A. and Hansson, T.. (2022) Exploring a tetrahydroquinoline antimalarial hit from the medicines for malaria pathogen box and the identification of its mode of resistance as PfeEF2. ChemMedChem, 17 (22). e202200393.

de Vries, L. E. and Jansen, P. A. M. and Barcelo, C. and Munro, J. and Verhoef, J. M. J. and Pasaje, C. F. A. and Rubiano, K. and Striepen, J. and Abla, N. and Berning, L. and Bolscher, J. M. and Demarta-Gatsi, C. and Henderson, R. W. M. and Huijs, T. and Koolen, K. M. J. and Tumwebaze, P. K. and Yeo, T. and Aguiar, A. C. C. and Angulo-Barturen, I. and Churchyard, A. and Baum, J. and Fernandez, B. C. and Fuchs, A. and Gamo, F. J. and Guido, R. V. C. and Jimenez-Diaz, M. B. and Pereira, D. B. and Rochford, R. and Roesch, C. and Sanz, L. M. and Trevitt, G. and Witkowski, B. and Wittlin, S. and Cooper, R. A. and Rosenthal, P. J. and Sauerwein, R. W. and Schalkwijk, J. and Hermkens, P. H. H. and Bonnert, R. V. and Campo, B. and Fidock, D. A. and Llinas, M. and Niles, J. C. and Kooij, T. W. A. and Dechering, K. J.. (2022) Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nat Commun, 13. p. 2158.

Knaab, T. C. and Held, J. and Burckhardt, B. B. and Rubiano, K. and Okombo, J. and Yeo, T. and Mok, S. and Uhlemann, A. C. and Lungerich, B. and Fischli, C. and Pessanha de Carvalho, L. and Mordmüller, B. and Wittlin, S. and Fidock, D. A. and Kurz, T.. (2021) 3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting Plasmodium falciparum. Journal of medicinal chemistry, 64 (6). pp. 3035-3047.

Xie, S. C. and Metcalfe, R. D. and Mizutani, H. and Puhalovich, T. and Hanssen, E. and Morton, C. J. and Du, Y. and Dogovski, C. and Huang, S. C. and Ciavarri, J. and Hales, P. and Griffin, R. J. and Cohen, L. H. and Chuang, B. C. and Wittlin, S. and Deni, I. and Yeo, T. and Ward, K. E. and Barry, D. C. and Liu, B. and Gillett, D. L. and Crespo-Fernandez, B. F. and Ottilie, S. and Mittal, N. and Churchyard, A. and Ferguson, D. and Aguiar, A. C. C. and Guido, R. V. C. and Baum, J. and Hanson, K. K. and Winzeler, E. A. and Gamo, F. J. and Fidock, D. A. and Baud, D. and Parker, M. W. and Brand, S. and Dick, L. R. and Griffin, M. D. W. and Gould, A. E. and Tilley, L.. (2021) Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proc Natl Acad Sci U S A, 118 (39). e2107213118.

Le Manach, C. and Dam, J. and Woodland, J. G. and Kaur, G. and Khonde, L. P. and Brunschwig, C. and Njoroge, M. and Wicht, K. J. and Horatscheck, A. and Paquet, T. and Boyle, G. A. and Gibhard, L. and Taylor, D. and Lawrence, N. and Yeo, T. and Mok, S. and Eastman, R. T. and Dorjsuren, D. and Talley, D. C. and Guo, H. and Simeonov, A. and Reader, J. and van der Watt, M. and Erlank, E. and Venter, N. and Zawada, J. W. and Aswat, A. and Nardini, L. and Coetzer, T. L. and Lauterbach, S. B. and Bezuidenhout, B. C. and Theron, A. and Mancama, D. and Koekemoer, L. L. and Birkholtz, L. M. and Wittlin, S. and Delves, M. and Ottilie, S. and Winzeler, E. A. and von Geldern, T. W. and Smith, D. and Fidock, D. A. and Street, L. J. and Basarab, G. S. and Duffy, J. and Chibale, K.. (2021) Identification and profiling of a novel diazaspiro[3.4]octane chemical series active against multiple stages of the human malaria parasite Plasmodium falciparum and optimization efforts. Journal of medicinal chemistry, 64 (4). pp. 2291-2309.

Lawong, A. and Gahalawat, S. and Okombo, J. and Striepen, J. and Yeo, T. and Mok, S. and Deni, I. and Bridgford, J. L. and Niederstrasser, H. and Zhou, A. and Posner, B. and Wittlin, S. and Gamo, F. J. and Crespo, B. and Churchyard, A. and Baum, J. and Mittal, N. and Winzeler, E. and Laleu, B. and Palmer, M. J. and Charman, S. A. and Fidock, D. A. and Ready, J. M. and Phillips, M. A.. (2021) Novel antimalarial tetrazoles and amides active against the hemoglobin degradation pathway in Plasmodium falciparum. Journal of medicinal chemistry, 64 (5). pp. 2739-2761.

Palmer, M. J. and Deng, X. and Watts, S. and Krilov, G. and Gerasyuto, A. and Kokkonda, S. and El Mazouni, F. and White, J. and White, K. L. and Striepen, J. and Bath, J. and Schindler, K. A. and Yeo, T. and Shackleford, D. M. and Mok, S. and Deni, I. and Lawong, A. and Huang, A. and Chen, G. and Wang, W. and Jayaseelan, J. and Katneni, K. and Patil, R. and Saunders, J. and Shahi, S. P. and Chittimalla, R. and Angulo-Barturen, I. and Jimenez-Diaz, M. B. and Wittlin, S. and Tumwebaze, P. K. and Rosenthal, P. J. and Cooper, R. A. and Aguiar, A. C. C. and Guido, R. V. C. and Pereira, D. B. and Mittal, N. and Winzeler, E. A. and Tomchick, D. R. and Laleu, B. and Burrows, J. N. and Rathod, P. K. and Fidock, D. A. and Charman, S. A. and Phillips, M. A.. (2021) Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series. Journal of medicinal chemistry, 64 (9). pp. 6085-6136.

Okaniwa, M. and Shibata, A. and Ochida, A. and Akao, Y. and White, K. L. and Shackleford, D. M. and Duffy, S. and Lucantoni, L. and Dey, S. and Striepen, J. and Yeo, T. and Mok, S. and Aguiar, A. C. C. and Sturm, A. and Crespo, B. and Sanz, L. M. and Churchyard, A. and Baum, J. and Pereira, D. B. and Guido, R. V. C. and Dechering, K. J. and Wittlin, S. and Uhlemann, A. C. and Fidock, D. A. and Niles, J. C. and Avery, V. M. and Charman, S. A. and Laleu, B.. (2021) Repositioning and characterization of 1-(pyridin-4-yl)pyrrolidin-2-one derivatives as Plasmodium cytoplasmic prolyl-trna synthetase inhibitors. ACS Infect Dis, 7 (6). pp. 1680-1689.

Murithi, J. M. and Pascal, C. and Bath, J. and Boulenc, X. and Gnadig, N. F. and Pasaje, C. F. A. and Rubiano, K. and Yeo, T. and Mok, S. and Klieber, S. and Desert, P. and Jimenez-Diaz, M. B. and Marfurt, J. and Rouillier, M. and Cherkaoui-Rbati, M. H. and Gobeau, N. and Wittlin, S. and Uhlemann, A. C. and Price, R. N. and Wirjanata, G. and Noviyanti, R. and Tumwebaze, P. and Cooper, R. A. and Rosenthal, P. J. and Sanz, L. M. and Gamo, F. J. and Joseph, J. and Singh, S. and Bashyam, S. and Augereau, J. M. and Giraud, E. and Bozec, T. and Vermat, T. and Tuffal, G. and Guillon, J. M. and Menegotto, J. and Salle, L. and Louit, G. and Cabanis, M. J. and Nicolas, M. F. and Doubovetzky, M. and Merino, R. and Bessila, N. and Angulo-Barturen, I. and Baud, D. and Bebrevska, L. and Escudie, F. and Niles, J. C. and Blasco, B. and Campbell, S. and Courtemanche, G. and Fraisse, L. and Pellet, A. and Fidock, D. A. and Leroy, D.. (2021) The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance. Sci Transl Med, 13 (603). eabg6013.

This list was generated on Mon Jun 5 08:33:18 2023 CEST.