Items where Author is "Spiegelman, B. M."

2008

Choi, C. S. and Befroy, D. E. and Codella, R. and Kim, S. and Reznick, R. M. and Hwang, Y. -J. and Liu, Z. -X. and Lee, H. -Y. and Distefano, A. and Samuel, V. T. and Zhang, D. and Cline, G. W. and Handschin, C. and Lin, J. and Petersen, K. F. and Spiegelman, B. M. and Shulman, G. I.. (2008) Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, H. 50. pp. 19926-19931.

2007

Rohas, L. M. and St-Pierre, J. and Uldry, M. and Jager, S. and Handschin, C. and Spiegelman, B. M.. (2007) A fundamental system of cellular energy homeostasis regulated by PGC-1α. Proceedings of the National Academy of Sciences of the United States of America, 104 (19). pp. 7933-7938.

Jager, S. and Handschin, C. and St-Pierre, J. and Spiegelman, B. M.. (2007) AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α. Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, H. 29. pp. 12017-12022.

Handschin, C. and Choi, C. S. and Chin, S. and Kim, S. and Kawamori, D. and Kurpad, A. J. and Neubauer, N. and Hu, J. and Mootha, V. K. and Kim, Y. -B. and Kulkarni, R. N. and Shulman, G. I. and Spiegelman, B. M.. (2007) Abnormal glucose homeostasis in skeletal muscle–specific PGC-1α knockout mice reveals skeletal muscle–pancreatic β cell crosstalk. Journal of Clinical Investigation, Vol. 117, H. 11. pp. 3463-3474.

Handschin, C. and Kobayashi, Y. M. and Chin, S. and Seale, P. and Campbell, K. P. and Spiegelman, B. M.. (2007) PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. Genes & development, Vol. 21, H. 7. pp. 770-783.

Handschin, C. and Chin, S. and Li, P. and Liu, F. and Maratos-Flier, E. and Lebrasseur, N. K. and Yan, Z. and Spiegelman, B. M.. (2007) Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals. Journal of Biological Chemistry, 282 (41). pp. 30014-30021.

2006

Sandri, M. and Lin, J. and Handschin, C. and Yang, W. and Arany, Z. P. and Lecker, S. H. and Goldberg, A. L. and Spiegelman, B. M.. (2006) PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, H. 44. pp. 16260-16265.

Rhee, J. and Ge, H. and Yang, W. and Fan, M. and Handschin, C. and Cooper, M. and Lin, J. and Li, C. and Spiegelman, B. M.. (2006) Partnership of PGC-1α and HNF4α in the regulation of lipoprotein metabolism. Journal of Biological Chemistry, 281 (21). pp. 14683-14690.

Handschin, C. and Spiegelman, B. M.. (2006) Peroxisome proliferator-activated receptor γ coactivator 1 coactivators, energy homeostasis, and metabolism. Endocrine reviews, Vol. 27, H. 7. pp. 728-735.

St-Pierre, J. and Drori, S. and Uldry, M. and Silvaggi, J. M. and Rhee, J. and Jager, S. and Handschin, C. and Zheng, K. and Lin, J. and Yang, W. and Simon, D. K. and Bachoo, R. and Spiegelman, B. M.. (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell, Vol. 127, H. 2. pp. 397-408.

2005

Lin, J. and Yang, R. and Tarr, P. T. and Wu, P. -H. and Handschin, C. and Li, S. and Yang, W. and Pei, L. and Uldry, M. and Tontonoz, P. and Newgard, C. B. and Spiegelman, B. M.. (2005) Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β coactivation of SREBP. Cell, Vol. 120, H. 2. pp. 261-273.

Lin, J. and Handschin, C. and Spiegelman, B. M.. (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metabolism, Vol. 1, H. 6. pp. 361-370.

Handschin, C. and Lin, J. and Rhee, J. and Peyer, A. -K. and Chin, S. and Wu, P. -H. and Meyer, U. A. and Spiegelman, B. M.. (2005) Nutritional Regulation of Hepatic Heme Biosynthesis and Porphyria through PGC-1α. Cell, Vol. 122, H. 4. pp. 505-515.

Arany, Z. and He, H. and Lin, J. and Hoyer, K. and Handschin, C. and Toka, O. and Ahmad, F. and Matsui, T. and Chin, S. and Wu, P. -H. and Rybkin, I. I. and Shelton, J. M. and Manieri, M. and Cinti, S. and Schoen, F. J. and Bassel-Duby, R. and Rosenzweig, A. and Ingwall, J. S. and Spiegelman, B. M.. (2005) Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle. Cell Metabolism, Vol. 1, H. 4. pp. 259-271.

2004

Fan, M. and Rhee, J. and St-Pierre, J. and Handschin, C. and Puigserver, P. and Lin, J. and Jaeger, S. and Erdjument-Bromage, H. and Tempst, P. and Spiegelman, B. M.. (2004) Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α : modulation by p38 MAPK. Genes & development, Vol. 18, H. 3. pp. 278-289.

2003

Handschin, C. and Rhee, J. and Lin, J. and Tarr, P. T. and Spiegelman, B. M.. (2003) An An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle. Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, H. 12. pp. 7111-7116.