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Items where Author is "Kleeb, Simon"

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Number of items: 10.

2017

Pang, Lijuan and Bezençon, Jacqueline and Kleeb, Simon and Rabbani, Said and Sigl, Anja and Smiesko, Martin and Sager, Christoph P. and Eris, Deniz and Schwardt, Oliver and Ernst, Beat. (2017) FimH antagonists - solubility vs. permeability. In: Carbohydrate Chemistry. London, pp. 248-273.

Mayer, Katharina and Eris, Deniz and Schwardt, Oliver and Sager, Christoph P. and Rabbani, Said and Kleeb, Simon and Ernst, Beat. (2017) Urinary Tract Infection: Which Conformation of the Bacterial Lectin FimH Is Therapeutically Relevant? Journal of Medicinal Chemistry, 60 (13). pp. 5646-5662.

2016

Kleeb, Simon and Jiang, Xiaohua and Frei, Priska and Sigl, Anja and Bezençon, Jacqueline and Bamberger, Karen and Schwardt, Oliver and Ernst, Beat. (2016) FimH Antagonists: Phosphate Prodrugs Improve Oral Bioavailability. Journal of Medicinal Chemistry, 59 (7). pp. 3163-3182.

Schönemann, Wojciech and Kleeb, Simon and Dätwyler, Philipp and Schwardt, Oliver and Ernst, Beat. (2016) Prodruggability of Carbohydrates - Oral FimH Antagonists. Canadian Journal of Chemistry, 94 (11). pp. 909-919.

2015

Kleeb, Simon and Pang, Lijuan and Mayer, Katharina and Eris, Deniz and Sigl, Anja and Preston, Roland C. and Zihlmann, Pascal and Sharpe, Timothy and Jakob, Roman P. and Abgottspon, Daniela and Hutter, Aline S. and Scharenberg, Meike and Jiang, Xiaohua and Navarra, Giulio and Rabbani, Said and Smiesko, Martin and Lüdin, Nathalie and Bezençon, Jacqueline and Schwardt, Oliver and Maier, Timm and Ernst, Beat. (2015) FimH Antagonists: Bioisosteres To Improve the in Vitro and in Vivo PK/PD Profile. Journal of Medicinal Chemistry, 58 (5). pp. 2221-2239.

Kleeb, Simon. Physicochemical and pharmacokinetic characterization of carbohydrate mimetics. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

2012

Jiang, Xiaohua and Abgottspon, Daniela and Kleeb, Simon and Rabbani, Said and Scharenberg, Meike and Wittwer, Matthias and Haug, Martina and Schwardt, Oliver and Ernst, Beat. (2012) Anti-adhesion therapy for urinary tract infections - a balanced PK/PD-profile proved to be key for success. Journal of Medicinal Chemistry, 55 (10). pp. 4700-4713.

Pang, Lijuan and Kleeb, Simon and Lemme, Katrin and Rabbani, Said and Scharenberg, Meike and Zalewski, Adam and Schädler, Florentina and Schwardt, Oliver and Ernst, Beat. (2012) FimH Antagonists: Structure-Activity and Structure-Property Relationships for Biphenyl α-D-Mannopyranosides. ChemMedChem, 7 (8). pp. 1404-1422.

2011

Schwardt, Oliver and Rabbani, Said and Hartmann, Margrit and Abgottspon, Daniela and Wittwer, Matthias and Kleeb, Simon and Zalewski, Adam and Smiesko, Martin and Cutting, Brian and Ernst, Beat. (2011) Design, Synthesis and Biological Evaluation of Mannosyl Triazoles as FimH Antagonists. Bioorganic & Medicinal Chemistry, 19 (21). pp. 6454-6473.

2010

Klein, Tobias and Abgottspon, Daniela and Wittwer, Matthias and Rabbani, Said and Herold, Janno and Jiang, Xiaohua and Kleeb, Simon and Lüthi, Christine and Scharenberg, Meike and Bezençcon, Jacqueline and Gubler, Erich and Pang, Lijuan and Smiesko, Martin and Cutting, Brian and Schwardt, Oliver and Ernst, Beat. (2010) FimH Antagonists for the Oral Treatment of Urinary Tract Infections : From Design and Synthesis to In Vitro and In Vivo Evaluation. Journal of Medicinal Chemistry, 53 (24). pp. 8627-8641.

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