Items where Author is "Keiser, J."
Number of items: 180. 2023Coffeng, L. E. and Vlaminck, J. and Cools, P. and Denwood, M. and Albonico, M. and Ame, S. M. and Ayana, M. and Dana, D. and Cringoli, G. and de Vlas, S. J. and Fenwick, A. and French, M. and Kazienga, A. and Keiser, J. and Knopp, S. and Leta, G. and Matoso, L. F. and Maurelli, M. P. and Montresor, A. and Mirams, G. and Mekonnen, Z. and Corrêa-Oliveira, R. and Pinto, S. A. and Rinaldi, L. and Sayasone, S. and Steinmann, P. and Thomas, E. and Vercruysse, J. and Levecke, B.. (2023) A general framework to support cost-efficient fecal egg count methods and study design choices for large-scale STH deworming programs-monitoring of therapeutic drug efficacy as a case study. PLoS Negl Trop Dis, 17 (5). e0011071. Cappuccino, C. and Spoletti, E. and Renni, F. and Muntoni, E. and Keiser, J. and Voinovich, D. and Perissutti, B. and Lusi, M.. (2023) Co-crystalline solid solution affords a high-soluble and fast-absorbing form of praziquantel. Mol Pharm, 20 (4). pp. 2009-2016. Mrimi, E. C. and Palmeirim, M. S. and Minja, E. G. and Long, K. Z. and Keiser, J.. (2023) Correlation of cytokines with parasitic infections, undernutrition and micronutrient deficiency among schoolchildren in rural Tanzania: a cross-sectional study. Nutrients, 15 (8). p. 1916. Kasago, F. M. and Häberli, C. and Keiser, J. and Masamba, W.. (2023) Design, synthesis and evaluation of praziquantel analogues and new molecular hybrids as potential antimalarial and anti-schistosomal agents. Molecules, 28 (13). p. 5184. Easland, E. and Biendl, S. and Keiser, J.. (2023) Development of a hookworm egg hatching assay to determine the ovicidal effects of anthelminthics. Parasit Vectors, 16. p. 157. Welsche, S. and Mrimi, E. C. and Hattendorf, J. and Hürlimann, E. and Ali, S. M. and Keiser, J.. (2023) Efficacy and safety of moxidectin and albendazole compared with ivermectin and albendazole coadministration in adolescents infected with Trichuris trichiura in Tanzania: an open-label, non-inferiority, randomised, controlled, phase 2/3 trial. The Lancet infectious diseases, 23 (3). pp. 331-340. Mrimi, E. C. and Welsche, S. and Ali, S. M. and Hattendorf, J. and Keiser, J.. (2023) Emodepside for Trichuris trichiura and hookworm infection. The New England journal of medicine, 388 (20). pp. 1863-1875. Muya, K. and Kalonji, M. and Ilunga, N. W. and Maseho, M. and Kitambala, M. and Kalonda, M. and Ndoumba, K. and Byanga, K. and Wright, C. W. and Häberli, C. and Keiser, J. and Simbi, L.. (2023) Evaluation of 43 species of Congolese medicinal plants used traditionally for the treatment of schistosomiasis leading to the isolation of an anti-schistosomal phaeophytin from Pseudolachnostylis maprouneifolia Pax. J Ethnopharmacol, 315. p. 116688. Specht, S. and Keiser, J.. (2023) Helminth infections: enabling the World Health Organization road map. Int J Parasitol, 53 (8). pp. 411-414. Coulibaly, J. T. and Silue, K. D. and Armstrong, M. and Díaz de León Derby, M. and D'Ambrosio, M. V. and Fletcher, D. A. and Keiser, J. and Fisher, K. and Andrews, J. R. and Bogoch, I. I.. (2023) High sensitivity of mobile phone microscopy screening for Schistosoma haematobium in Azaguié, Côte d'Ivoire. The American journal of tropical medicine and hygiene, 108 (1). pp. 41-43. Biendl, S. and Häberli, C. and Chen, G. and Wang, W. and Zhong, L. and Saunders, J. and Pham, T. and Wang, X. and Wu, J. and Charman, S. A. and Vennerstrom, J. L. and Keiser, J.. (2023) In vitro; and; in vivo; antischistosomal activity profiling and pharmacokinetics of ozonide carboxylic acids. ACS Infect Dis, 9 (3). pp. 643-652. Hürlimann, E. and Hofmann, D. and Keiser, J.. (2023) Ivermectin and moxidectin against soil-transmitted helminth infections. Trends in parasitology, 39 (4). pp. 272-284. Friedrich, L. and Park, S. K. and Ballard, P. and Ho Baeurle, T. H. and Maillard, D. and Bödding, M. and Keiser, J. and Marchant, J. S. and Spangenberg, T.. (2023) Metabolism of (R)-Praziquantel versus the activation of a Parasite Transient Receptor Potential Melastatin ion channel. ChemMedChem, 18 (18). e202300140. D'Abbrunzo, I. and Bianco, E. and Gigli, L. and Demitri, N. and Birolo, R. and Chierotti, M. R. and Keiser, J. and Häberli, C. and Voinovich, D. and Hasa, D. and Perissutti, B.. (2023) Praziquantel meets Niclosamide: a dual-drug antiparasitic cocrystal. International journal of pharmaceutics, 644. p. 123315. 2022Dube, M. and Llanes, D. and Saoud, M. and Rennert, R. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2022) Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: natural fungal compounds and synthetic derivatives with in vitro anthelmintic activities and antiproliferative effects against two human cancer cell lines. Molecules, 27 (9). p. 2950. Ren, R. and Wang, X. and Leas, D. A. and Häberli, C. and Cal, M. and Dong, Y. and Kaiser, M. and Keiser, J. and Vennerstrom, J. L.. (2022) Antischistosomal tetrahydro-γ-carboline sulfonamides. Bioorganic & medicinal chemistry letters, 59. p. 128546. Valderas-García, E. and Häberli, C. and Álvarez-Bardón, M. and Escala, N. and Castilla-Gómez de Agüero, V. and de la Vega, J. and Del Olmo, E. and Balaña-Fouce, R. and Keiser, J. and Martínez-Valladares, M.. (2022) Benzimidazole and aminoalcohol derivatives show in vitro anthelmintic activity against Trichuris muris and Heligmosomoides polygyrus. Parasit Vectors, 15. p. 243. Smit, C. and Hofmann, D. and Sayasone, S. and Keiser, J. and Pfister, M.. (2022) Characterization of the population pharmacokinetics of moxidectin in adults infected with strongyloides stercoralis: support for a fixed-dose treatment regimen. Clinical pharmacokinetics, 61. pp. 123-132. Noce, B. and Di Bello, E. and Zwergel, C. and Fioravanti, R. and Valente, S. and Rotili, D. and Masotti, A. and Ansari, M. S. Z. and Trisciuoglio, D. and Chakrabarti, A. and Romier, C. and Robaa, D. and Sippl, W. and Jung, M. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages. ChemMedChem. In press. Falcoz, C. and Guzy, S. and Kovac, J. and Meister, I. and Coulibaly, J. and Sayasone, S. and WEsche, D. and Lin, Y. W. and Keiser, J.. (2022) Correction to: R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini. J Pharmacokinet Pharmacodyn, 49 (3). p. 395. Angeli, A. and Ferraroni, M. and Carta, F. and Häberli, C. and Keiser, J. and Costantino, G. and Supuran, C. T.. (2022) Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37 (1). pp. 1479-1494. Schneeberger, P. H. H. and Gueuning, M. and Welsche, S. and Hürlimann, E. and Dommann, J. and Haberli, C. and Frey, J. E. and Sayasone, S. and Keiser, J.. (2022) Different gut microbial communities correlate with efficacy of albendazole-ivermectin against soil-transmitted helminthiases. Nat Commun, 13. p. 1063. Biendl, S. and Häberli, C. and Keiser, J.. (2022) Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box. Expert Rev Anti Infect Ther, 20 (4). pp. 621-629. Di Bello, E. and Noce, B. and Fioravanti, R. and Zwergel, C. and Valente, S. and Rotili, D. and Fianco, G. and Trisciuoglio, D. and Mourão, M. M. and Sales, P. and Jr., and Lamotte, S. and Prina, E. and Späth, G. F. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni. ACS Infect Dis, 8 (7). pp. 1356-1366. Hürlimann, E. and Keller, L. and Patel, C. and Welsche, S. and Hattendorf, J. and Ali, S. M. and Ame, S. M. and Sayasone, S. and Coulibaly, J. T. and Keiser, J.. (2022) Efficacy and safety of co-administered ivermectin and albendazole in school-aged children and adults infected with; Trichuris trichiura; in Côte d'Ivoire, Laos, and Pemba Island, Tanzania: a double-blind, parallel-group, phase 3, randomised controlled trial. The Lancet infectious diseases, 22 (1). pp. 123-135. Qian, M. B. and Patel, C. and Palmeirim, M. S. and Wang, X. and Schindler, C. and Utzinger, J. and Zhou, X. N. and Keiser, J.. (2022) Efficacy of drugs against clonorchiasis and opisthorchiasis: a systematic review and network meta-analysis. Lancet Microbe, 3 (8). e616-e624. Olliaro, P. L. and Vaillant, M. T. and Diawara, A. and Speich, B. and Albonico, M. and Utzinger, J. and Keiser, J.. (2022) Egg excretion indicators for the measurement of soil-transmitted helminth response to treatment. PLoS Negl Trop Dis, 16 (8). e0010593. Harrington, S. and Knox, J. J. and Burns, A. R. and Choo, K. L. and Au, A. and Kitner, M. and Haeberli, C. and Pyche, J. and D'Amata, C. and Kim, Y. H. and Volpatti, J. R. and Guiliani, M. and Snider, J. and Wong, V. and Palmeira, B. M. and Redman, E. M. and Vaidya, A. S. and Gilleard, J. S. and Stagljar, I. and Cutler, S. R. and Kulke, D. and Dowling, J. J. and Yip, C. M. and Keiser, J. and Zasada, I. and Lautens, M. and Roy, P. J.. (2022) Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release. Commun Biol, 5. p. 865. Cantara, A. and Luo, Y. and Dobrovolna, M. and Bohalova, N. and Fojta, M. and Verga, D. and Guittat, L. and Cucchiarini, A. and Savrimoutou, S. and Häberli, C. and Guillon, J. and Keiser, J. and Brazda, V. and Mergny, J. L.. (2022) G-quadruplexes in helminth parasites. Nucleic Acids Res, 50 (5). pp. 2719-2735. Walker, M. and Freitas, L. T. and Halder, J. B. and Brack, M. and Keiser, J. and King, C. H. and Levecke, B. and Ai-Lian Lim, Y. and Pieri, O. and Sow, D. and Stothard, J. R. and Webster, J. P. and Zhou, X. N. and Terry, R. F. and Guérin, P. J. and Basáñez, M. G.. (2022) Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data. Wellcome Open Res, 7. p. 5. Probst, A. and Biendl, S. and Keiser, J.. (2022) Improving translational power in antischistosomal drug discovery. Advances in parasitology, 117. pp. 47-73. Taljaard, L. and Probst, A. and Tornow, R. and Keiser, J. and Haynes, R. K. and van der Kooy, F.. (2022) In vitro antischistosomal activity of Artemisia annua and Artemisia afra extracts. Phytomed Plus, 2 (3). p. 100279. Mrimi, E. C. and Palmeirim, M. S. and Minja, E. G. and Long, K. Z. and Keiser, J.. (2022) Malnutrition, anemia, micronutrient deficiency and parasitic infections among schoolchildren in rural Tanzania. PLoS Negl Trop Dis, 16 (3). e0010261. Dube, M. and Raphane, B. and Sethebe, B. and Seputhe, N. and Tiroyakgosi, T. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N. and Andrae-Marobela, K.. (2022) Medicinal plant preparations administered by botswana traditional health practitioners for treatment of worm infections show anthelmintic activities. Plants (Basel), 11 (21). p. 2945. Grolimund, C. and Bärenbold, O. and Utzinger, J. and Keiser, J. and Vounatsou, P.. (2022) Modeling the effect of different drugs and treatment regimen for hookworm on cure and egg reduction rates taking into account diagnostic error. PLoS Negl Trop Dis, 16 (10). e0010810. Hamway, Y. and Zimmermann, K. and Blommers, M. J. J. and Sousa, M. and Häberli, C. and Kulkarni, S. and Skalicky, S. and Hackl, M. and Götte, M. and Keiser, J. and da Costa, C. P. and Spangenberg, T. and Azzaoui, K.. (2022) Modulation of host-parasite interactions with small molecules targeting Schistosoma mansoni microRNAs. ACS Infect Dis, 8. 2028−2034. Coulibaly, J. T. and Hürlimann, E. and Patel, C. and Silué, D. K. and Avenié, D. J. and Kouamé, N. A. and Silué, U. M. and Keiser, J.. (2022) Optimizing implementation of preventive chemotherapy against soil-transmitted helminthiasis and intestinal schistosomiasis using high-resolution data: Field-based experiences from Côte d'Ivoire. Diseases, 10 (4). p. 66. Hofmann, D. and Smit, C. and Sayasone, S. and Pfister, M. and Keiser, J.. (2022) Optimizing moxidectin dosing for Strongyloides stercoralis infections: insights from pharmacometric modeling. Clin Transl Sci, 15 (3). pp. 700-708. Hofmann, D. and Brussee, J. M. and Schulz, J. D. and Coulibaly, J. T. and Pfister, M. and Keiser, J.. (2022) Pharmacokinetic modelling and simulation to optimize albendazole dosing in hookworm- or Trichuris trichiura-infected infants to adults. J Antimicrob Chemother, 77 (4). pp. 1082-1093. Probst, A. and Hofmann, D. and Fedorova, O. S. and Mazeina, S. V. and Sokolova, T. S. and Golovach, E. and Keiser, J.. (2022) Pharmacokinetics of ascending doses of praziquantel in adults infected with Opisthorchis felineus in Western Siberia, Russian Federation. Antimicrobial agents and chemotherapy, 66 (10). e00526-22. Hassan, M. M. and Sedighi, A. and Olaoye, O. O. and Haberli, C. and Merz, A. and Ramos-Morales, E. and de Araujo, E. D. and Romier, C. and Jung, M. and Keiser, J. and Gunning, P. T.. (2022) Phenotypic screening of histone deacetylase (HDAC) inhibitors against Schistosoma mansoni. ChemMedChem. e202100622. Falcoz, C. and Guzy, S. and Kovač, J. and Meister, I. and Coulibaly, J. and Sayasone, S. and Wesche, D. and Lin, Y. W. and Keiser, J.. (2022) R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with; Schistosoma mansoni; and; S. haematobium; and Lao adults infected with; Opisthorchis viverrini. J Pharmacokinet Pharmacodyn, 49 (3). pp. 293-310. Ravaynia, P. S. and Biendl, S. and Grassi, F. and Keiser, J. and Hierlemann, A. and Modena, M. M.. (2022) Real-time and automated monitoring of antischistosomal drug activity profiles for screening of compound libraries. iScience, 25 (4). p. 104087. Taki, A. C. and Wang, T. and Nguyen, N. N. and Ang, C. S. and Leeming, M. G. and Nie, S. and Byrne, J. J. and Young, N. D. and Zheng, Y. and Ma, G. and Korhonen, P. K. and Koehler, A. V. and Williamson, N. A. and Hofmann, A. and Chang, B. C. H. and Haberli, C. and Keiser, J. and Jabbar, A. and Sleebs, B. E. and Gasser, R. B.. (2022) Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868. Front Pharmacol, 13. p. 1014804. Kersting, L. and Kuhn, L. and Anokhin, M. and Schuster, F. and Häberli, C. and Sambyal, S. and Kumar, H. M. S. and Keiser, J. and Alabugin, I. and Tsogoeva, S. B.. (2022) Visible-light-driven metal-free C-H functionalization: access to new bioactive tetrahydroisoquinoline-butenolide hybrids via domino amine oxidation/vinylogous mannich reaction. ChemPhotoChem, 6 (8). e202200109. Herath, H. M. P. D. and Taki, A. C. and Rostami, A. and Jabbar, A. and Keiser, J. and Geary, T. G. and Gasser, R. B.. (2022) Whole-organism phenotypic screening methods used in early-phase anthelmintic drug discovery. Biotechnol Adv, 57. p. 107937. 2021Palmeirim, M. S. and Mrimi, E. C. and Minja, E. G. and Samson, A. J. and Keiser, J.. (2021) A cross-sectional survey on parasitic infections in schoolchildren in a rural Tanzanian community. Acta Trop, 213. p. 105737. Jittamala, P. and Monteiro, W. and Smit, M. R. and Pedrique, B. and Specht, S. and Chaccour, C. J. and Dard, C. and Del Giudice, P. and Khieu, V. and Maruani, A. and Failoc-Rojas, V. E. and Saez-de-Ocariz, M. and Soriano-Arandes, A. and Piquero-Casals, J. and Faisant, A. and Brenier-Pinchart, M. P. and Wimmersberger, D. and Coulibaly, J. T. and Keiser, J. and Boralevi, F. and Sokana, O. and Marks, M. and Engelman, D. and Romani, L. and Steer, A. C. and von Seidlein, L. and White, N. J. and Harriss, E. and Stepniewska, K. and Humphreys, G. S. and Kennon, K. and Guerin, P. J. and Kobylinski, K. C.. (2021) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: is it time to reconsider the current contraindication? PLoS Negl Trop Dis, 15 (3). e0009144. Debbert, S. L. and Hintz, M. J. and Bell, C. J. and Earl, K. R. and Forsythe, G. E. and Häberli, C. and Keiser, J.. (2021) Activities of quinoxaline, nitroquinoxaline and [1,2,4]triazolo[4,3-a]quinoxaline analogs of MMV007204 against; Schistosoma mansoni. Antimicrobial agents and chemotherapy, 65 (3). e01370-20. Dube, M. and Saoud, M. and Rennert, R. and Fotso, G. W. and Andrae-Marobela, K. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2021) Anthelmintic activity and cytotoxic effects of compounds isolated from the fruits of Ozoroa insignis del. (Anacardiaceae). Biomolecules, 11 (12). p. 1893. Keiser, J. and Häberli, C.. (2021) Assessment of FDA-approved drugs against Strongyloides ratti in vitro and in vivo to identify potentially active drugs against strongyloidiasis. Parasit Vectors, 14. p. 615. Patel, C. and Keller, L. and Welsche, S. and Hattendorf, J. and Sayasone, S. and Ali, S. M. and Ame, S. M. and Coulibaly, J. T. and Hürlimann, E. and Keiser, J.. (2021) Assessment of fecal calprotectin and fecal occult blood as point-of-care markers for soil-transmitted helminth attributable intestinal morbidity in a case-control substudy conducted in Côte d'Ivoire, Lao PDR and Pemba Island, Tanzania. EClinicalMedicine, 32. p. 100724. Buchter, V. and Hofmann, D. and Häberli, C. and Keiser, J.. (2021) Characterization of moxidectin against; Strongyloides ratti:; in vitro; and; in vivo; activity and pharmacokinetics in the rat model. ACS Infect Dis, 7 (5). pp. 1069-1076. Hofmann, D. and Sayasone, S. and Keiser, J.. (2021) Development and validation of an LC-MS/MS method for the quantification of the anthelmintic drug moxidectin in a volumetric absorptive microsample, blood, and plasma: application to a pharmacokinetic study of adults infected with Strongyloides stercoralis in Laos. J Chromatogr B Analyt Technol Biomed Life Sci, 1166. p. 122556. Krücken, J. and Holden-Dye, L. and Keiser, J. and Prichard, R. K. and Townson, S. and Makepeace, B. L. and Hubner, M. P. and Hahnel, S. R. and Scandale, I. and Harder, A. and Kulke, D.. (2021) Development of emodepside as a possible adulticidal treatment for human onchocerciasis-the fruit of a successful industrial-academic collaboration. PLoS Pathog, 17 (7). e1009682. Patel, C. and Coulibaly, J. T. and Hofmann, D. and N'Gbesso, Y. and Hattendorf, J. and Keiser, J.. (2021) Efficacy and safety of albendazole in hookworm-infected preschool-aged children, school-aged children and adults in Côte d'Ivoire: a phase II randomized controlled dose-finding trial. Clinical infectious diseases, 73 (2). e494-e502. Hofmann, D. and Sayasone, S. and Sengngam, K. and Chongvilay, B. and Hattendorf, J. and Keiser, J.. (2021) Efficacy and safety of ascending doses of moxidectin against; Strongyloides stercoralis; infections in adults: a randomised, parallel-group, single-blinded, placebo-controlled, dose-ranging, phase 2a trial. Lancet Infect Dis, 21 (8). pp. 1151-1160. Welsche, S. and Mrimi, E. C. and Keller, L. and Hürlimann, E. and Hofmann, D. and Hattendorf, J. and Ali, S. M. and Keiser, J.. (2021) Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with Trichuris trichiura: a randomized controlled trial protocol. Gates Open Res, 5. p. 106. Keiser, J. and Häberli, C.. (2021) Evaluation of commercially available anthelminthics in laboratory models of human intestinal nematode infections. ACS Infect Dis, 7 (5). pp. 1177-1185. Lombardo, F. C. and Ravaynia, P. S. and Modena, M. M. and Hierlemann, A. and Keiser, J.. (2021) Evaluation of human liver microtissues for drug screening on Schistosoma mansoni schistosomula. ACS Infect Dis, 7 (7). pp. 1894-1900. Palmeirim, M. S. and Mohammed, U. A. and Ross, A. and Ame, S. M. and Ali, S. M. and Keiser, J.. (2021) Evaluation of two communication tools, slideshow and theater, to improve participants' understanding of a clinical trial in the informed consent procedure on Pemba Island, Tanzania. PLoS Negl Trop Dis, 15 (5). e0009409. Probst, A. and Chisanga, K. and Dziwornu, G. A. and Häberli, C. and Keiser, J. and Chibale, K.. (2021) Expanding the activity profile of pyrido[1,2-a]benzimidazoles: synthesis and evaluation of novel n(1)-1-phenylethanamine derivatives against Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1032-1043. Sy, I. and Margardt, L. and Ngbede, E. O. and Adah, M. I. and Yusuf, S. T. and Keiser, J. and Rehner, J. and Utzinger, J. and Poppert, S. and Becker, S. L.. (2021) Identification of adult Fasciola spp. using matrix-assisted laser/desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. Microorganisms, 9. p. 82. Sirak, B. and Asres, K. and Hailu, A. and Dube, M. and Arnold, N. and Häberli, C. and Keiser, J. and Imming, P.. (2021) In vitro antileishmanial and antischistosomal activities of anemonin isolated from the fresh leaves of Ranunculus multifidus forsk. Molecules, 26 (24). p. 7473. Probst, A. and Pujol, E. and Häberli, C. and Keiser, J. and Vázquez, S.. (2021) In vitro, in vivo, and ADME evaluation of SF5-containing N,N'-diarylureas as antischistosomal agents. Antimicrobial agents and chemotherapy, 65 (10). e0061521. Walker, M. and Cools, P. and Albonico, M. and Ame, S. M. and Ayana, M. and Dana, D. and Keiser, J. and Matoso, L. F. and Montresor, A. and Mekonnen, Z. and Corrêa-Oliveira, R. and Pinto, S. A. and Sayasone, S. and Vercruysse, J. and Vlaminck, J. and Levecke, B.. (2021) Individual responses to a single oral dose of albendazole indicate reduced efficacy against soil-transmitted helminths in an area with high drug pressure. PLoS Negl Trop Dis, 15 (10). e0009888. Keller, L. and Hürlimann, E. and Patel, C. and Welsche, S. and Sayasone, S. and Ali, S. M. and Ame, S. M. and Coulibaly, J. T. and Keiser, J.. (2021) Insights gained from conductinga randomised controlled trial onIvermectin-albendazole against Trichuris trichiura in Côte d'Ivoire, Lao PDR and Pemba Island. Advances in parasitology, 111. pp. 253-276. Keller, L. and Welsche, S. and Patel, C. and Sayasone, S. and Ali, S. M. and Ame, S. M. and Hattendorf, J. and Hürlimann, E. and Keiser, J.. (2021) Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania. PLoS Negl Trop Dis, 15 (6). e0009561. Nguyen, W. and Lee, E. F. and Evangelista, M. and Lee, M. and Harris, T. J. and Colman, P. M. and Smith, N. A. and Williams, L. B. and Jarman, K. E. and Lowes, K. N. and Häberli, C. and Keiser, J. and Smith, B. J. and Fairlie, W. D. and Sleebs, B. E.. (2021) Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a. ACS Infect Dis, 7 (5). pp. 1143-1163. Palmeirim, M. S. and Specht, S. and Scandale, I. and Gander-Meisterernst, I. and Chabicovsky, M. and Keiser, J.. (2021) Preclinical and clinical characteristics of the trichuricidal drug oxantel pamoate and clinical development plans: a review. Drugs, 81 (8). pp. 907-921. Partridge, F. A. and Bataille, C. J. R. and Forman, R. and Marriott, A. E. and Forde-Thomas, J. and Häberli, C. and Dinsdale, R. L. and O'Sullivan, J. D. B. and Willis, N. J. and Wynne, G. M. and Whiteland, H. and Archer, J. and Steven, A. and Keiser, J. and Turner, J. D. and Hoffmann, K. F. and Taylor, M. J. and Else, K. J. and Russell, A. J. and Sattelle, D. B.. (2021) Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1260-1274. Buchter, V. and Schneeberger, P. H. H. and Keiser, J.. (2021) Validation of a human-serum-based in vitro growth method for drug screening on juvenile development stages of Schistosoma mansoni. PLoS Negl Trop Dis, 15 (3). e0009313. 2020Twumasi, E. B. and Akazue, P. I. and Kyeremeh, K. and Gwira, T. M. and Keiser, J. and Cho-Ngwa, F. and Flint, A. and Anibea, B. and Bonsu, E. Y. and Amewu, R. K. and Amoah, L. E. and Appiah-Opong, R. and Osei-Safo, D.. (2020) Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents. PLoS Negl Trop Dis, 14 (12). e0008919. Palmeirim, M. S. and Bosch, F. and Ame, S. M. and Ali, S. M. and Hattendorf, J. and Keiser, J.. (2020) Efficacy, safety and acceptability of a new chewable formulationversusthe solid tablet of mebendazole against hookworm infections in children: an open-label, randomized controlled trial. EClinicalMedicine, 27. p. 100556. Palmeirim, M. S. and Ross, A. and Obrist, B. and Mohammed, U. A. and Ame, S. M. and Ali, S. M. and Keiser, J.. (2020) Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase caregivers knowledge? BMC medical ethics, 21. p. 1. Keller, L. and Patel, C. and Welsche, S. and Schindler, T. and Hürlimann, E. and Keiser, J.. (2020) Performance of the Kato-Katz method and real time polymerase chain reaction for the diagnosis of soil-transmitted helminthiasis in the framework of a randomised controlled trial: treatment efficacy and day-to-day variation. Parasit Vectors, 13. p. 517. 2019Hürlimann, E. and Keiser, J.. (2019) A single dose of ivermectin is sufficient for strongyloidiasis. The Lancet infectious diseases, 19 (11). pp. 1150-1151. Wimmersberger, D. and Schulz, J. D. and Keiser, J.. (2019) Antihelminthic efficacy against trichuriasis reply. Clinical infectious diseases, 69 (2). pp. 376-377. Keiser, J. and Utzinger, J.. (2019) Community-wide soil-transmitted helminth treatment is equity-effective. Lancet, 393 (10185). pp. 2011-2012. Wimmersberger, D. and Schulz, J. D. and Keiser, J.. (2019) Reply to Nalin. Clinical infectious diseases, 69 (2). pp. 376-377. Kyne, G. M. and Curtis, M. P. and Keiser, J. and Woods, D. J.. (2019) Soil-transmitted helminthiasis - challenges with discovery of novel anthelmintics. In: Neglected tropical diseases: drug discovery and development. Weinheim, pp. 227-251. 2018Schulz, J. D. and Neodo, A. and Coulibaly, J. T. and Keiser, J.. (2018) Development and validation of a LC-MS/MS method for ivermectin quantification in dried blood spots : application to a pharmacokinetic study in Trichuris trichiura-infected adults. Analytical Methods, 10. pp. 2901-2909. Moser, W. and Barenbold, O. and Mirams, G. J. and Cools, P. and Vlaminck, J. and Ali, S. M. and Ame, S. M. and Hattendorf, J. and Vounatsou, P. and Levecke, B. and Keiser, J.. (2018) Diagnostic comparison between FECPAKG2 and the Kato-Katz method for analyzing soil-transmitted helminth eggs in stool. PLoS neglected tropical diseases, 12 (6). e0006562. Palmeirim, M. S. and Ame, S. M. and Ali, S. M. and Hattendorf, J. and Keiser, J.. (2018) Efficacy and safety of a single dose versus a multiple dose regimen of mebendazole against hookworm infections in children : a randomised, double-blind trial. EClinicalMedicine, 1. pp. 7-13. Pasche, V. and Laleu, B. and Keiser, J.. (2018) Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni. Parasites and Vectors, 11. p. 298. 2017Keiser, J.. (2017) Jennifer Keiser - tackling drug resistance before it arises. Trends in parasitology, 33 (3). pp. 153-154. 2015Barda, B. D. and Keiser, J. and Albonico, M.. (2015) Human trichuriasis : diagnostics update. Current tropical medicine reports, 2. pp. 201-208. 2014Speich, B. and Utzinger, J. and Marti, H. and Ame, S. M. and Ali, S. M. and Albonico, M. and Keiser, J.. (2014) Comparison of the Kato-Katz method and ether-concentration technique for the diagnosis of soil-transmitted helminth infections in the framework of a randomised controlled trial. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Vol. 33, H. 5. pp. 815-822. Kljun, J. and Scott, A. J. and Rizner, T. L. and Keiser, J. and Turel, I.. (2014) Synthesis and biological evaluation of organoruthenium complexes with azole antifungal agents : first crystal structure of a tioconazole metal complex. Organometallics, Vol. 33, H. 7. pp. 1594-1601. Keiser, J. and Speich, B. and Utzinger, J.. (2014) The authors reply : Yasukawa K. comment to "Oxantel pamoate-albendazole for Trichuris trichiura infection". The New England journal of medicine, Vol. 370, H. 20. p. 1953. 2013Qian, M. B. and Yap, P. and Yang, Y. C. and Liang, H. and Jiang, Z. H. and Li, W. and Utzinger, J. and Zhou, X. N. and Keiser, J.. (2013) Accuracy of the Kato-Katz method and formalin-ether concentration technique for the diagnosis of Clonorchis sinensis, and implication for assessing drug efficacy. Parasites and Vectors, 6 (314). Keiser, J. and Tritten, L. and Silbereisen, A. and Speich, B. and Adelfio, R. and Vargas, M.. (2013) Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug. PLoS neglected tropical diseases, Vol. 7, H. 3 , e2119. Keiser, J. and Adelfio, R. and Vargas, M. and Odermatt, P. and Tesana, S.. (2013) Activity of tribendimidine and praziquantel combination therapy against the liver fluke Opisthorchis viverrini in vitro and in vivo. Journal of helminthology, Vol. 87, H. 2. pp. 252-256. Alles, R. and Puchkov, M. and Jablonski, C. and Speich, B. and Keiser, J. and Huwyler, J.. (2013) Development of oxantel tablets for pediatric clinical studies : a technical note. Journal of drug delivery science and technology, Vol. 23, H. 6. pp. 623-625. Qian, M. B. and Yap, P. and Yang, Y. C. and Liang, H. and Jiang, Z. H. and Li, W. and Tan, Y. G. and Zhou, H. and Utzinger, J. and Zhou, X. N. and Keiser, J.. (2013) Efficacy and safety of tribendimidine against Clonorchis sinensis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 56, H. 7 , e76-e82. Tsang, A. S. and Ingram, K. and Keiser, J. and Hibbert, D. B. and Todd, M. H.. (2013) Enhancing the usefulness of cross dehydrogenative coupling reactions with a removable protecting group. Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry, Vol. 11, H. 30. pp. 4921-4924. Vukcevic, M. and Zorzato, F. and Keck, S. and Tsakiris, D. A. and Keiser, J. and Maizels, R. M. and Treves, S.. (2013) Gain of function in the immune system caused by a ryanodine receptor 1 mutation. Journal of cell science, 126 (15). pp. 3485-3492. de Moraes, J. and Keiser, J. and Ingram, K. and Nascimento, C. and Yamaguchi, L. F. and Bittencourt, C. R. and Bemquerer, M. P. and Leite, J. R. and Kato, M. J. and Nakano, E.. (2013) In vitro synergistic interaction between amide piplartine and antimicrobial peptide dermaseptin against Schistosoma mansoni schistosomula and adult worms. Current medicinal chemistry, Vol. 20, H. 2. pp. 301-309. Keiser, J. and Manneck, T. and Kirchhofer, C. and Braissant, O.. (2013) Isothermal microcalorimetry to study the activity of triclabendazole and its metabolites on juvenile and adult Fasciola hepatica. Experimental parasitology : EP, Vol. 133, H. 3. pp. 265-268. Speich, B. and Marti, H. and Ame, S. M. and Ali, S. M. and Bogoch, I. I. and Utzinger, J. and Albonico, M. and Keiser, J.. (2013) Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide. Parasites and Vectors, 6 (3). Patra, M. and Ingram, K. and Pierroz, V. and Ferrari, S. and Spingler, B. and Gasser, R. B. and Keiser, J. and Gasser, G.. (2013) [(η(6) -praziquantel)Cr(CO)(3)] derivatives with remarkable in vitro anti-schistosomal activity. Chemistry : a European journal, Vol. 19, H. 7. pp. 2232-2235. 2012Keiser, J. and Vargas, M. and Winter, R.. (2012) Anthelminthic properties of mangostin and mangostin diacetate. Parasitology international, Vol. 61, H. 2. pp. 369-371. Koné, W. M. and Vargas, M. and Keiser, J.. (2012) Anthelmintic activity of medicinal plants used in Côte d'Ivoire for treating parasitic diseases. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 110, H. 6. pp. 2351-2362. Ingram, K. and Ellis, W. and Keiser, J.. (2012) Antischistosomal activities of mefloquine-related arylmethanols. Antimicrobial agents and chemotherapy, Vol. 56, H. 6. pp. 3207-3215. Thomsen, H. and Reider, K. and Franke, K. and Wessjohann, L. A. and Keiser, J. and Dagne, E. and Arnold, N.. (2012) Characterization of constituents and anthelmintic properties of Hagenia abyssinica. Scientia Pharmaceutica, 80 (2). pp. 433-446. Tritten, L. and Braissant, O. and Keiser, J.. (2012) Comparison of novel and existing tools for studying drug sensitivity against the hookworm Ancylostoma ceylanicum in vitro. Parasitology, Vol. 139, H. 3. pp. 348-357. Marxer, M. and Ingram, K. and Keiser, J.. (2012) Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula. Parasites and Vectors, 5 (164). Caffrey, C. R. and Utzinger, J. and Keiser, J.. (2012) Drug discovery for trematodiases : challenges and progress. In: Parasitic helminths : targets, screens, drugs and vaccines. Weinheim, pp. 323-337. Keiser, J. and Tritten, L. and Adelfio, R. and Vargas, M.. (2012) Effect of combinations of marketed human anthelmintic drugs against Trichuris muris in vitro and in vivo. Parasites and Vectors, 5 (292). Ziegelbauer, K. and Speich, B. and Mäusezahl, D. and Bos, R. and Keiser, J. and Utzinger, J.. (2012) Effect of sanitation on soil-transmitted helminth infection : systematic review and meta-analysis. PLoS medicine, Vol. 9, H. 1, e1001162. Speich, B. and Ame, S. M. and Ali, S. M. and Alles, R. and Hattendorf, J. and Utzinger, J. and Albonico, M. and Keiser, J.. (2012) Efficacy and safety of nitazoxanide, albendazole, and nitazoxanide-albendazole against Trichuris trichiura infection : a randomized controlled trial. PLoS neglected tropical diseases, Vol. 6, H. 6 , e1685. Coulibaly, J. T. and N'Gbesso, Y. K. and Knopp, S. and Keiser, J. and N'Goran, E. K. and Utzinger, J.. (2012) Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for Schistosoma mansoni and S. haematobium. PLoS neglected tropical diseases, Vol. 6, H. 12 , e1917. Lovis, L. and Mak, T. K. and Phongluxa, K. and Soukhathammavong, P. A. and Vonghachack, Y. and Keiser, J. and Vounatsou, P. and Tanner, M. and Hatz, C. and Utzinger, J. and Odermatt, P. and Akkhavong, K.. (2012) Efficacy of praziquantel against Schistosoma mekongi and Opisthorchis viverrini : a randomized, single-blinded dose-comparison trial. PLoS neglected tropical diseases, Vol. 6, H. 7 , e1726. Duthaler, U. and Huwyler, J. and Rinaldi, L. and Cringoli, G. and Keiser, J.. (2012) Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica. Veterinary parasitology, Vol. 186, H. 3-4. pp. 270-280. Patra, M. and Ingram, K. and Pierroz, V. and Ferrari, S. and Spingler, B. and Keiser, J. and Gasser, G.. (2012) Ferrocenyl derivatives of the anthelmintic praziquantel : design, synthesis and biological evaluation. Journal of medicinal chemistry, 55 (20). pp. 8790-8798. Fürst, T. and Keiser, J. and Utzinger, J.. (2012) Global burden of human food-borne trematodiasis : a systematic review and meta-analysis. The Lancet infectious diseases, Vol. 12, H. 3. pp. 210-221. Ingram, K. and Yaremenko, I. A. and Krylov, I. and Hofer, L. and Terent'ev, A. O. and Keiser, J.. (2012) Identification of antischistosomal leads by evaluating peroxides of beta-dicarbonyl compounds and their heteroanalogs : bridged 1,2,4,5-tetraoxanes and alphaperoxides, and beta,delta-triketones: tricyclic monoperoxides. Journal of medicinal chemistry, 55 (20). pp. 8700-8711. Ingram, K. and Schiaffo, C. E. and Sittiwong, W. and Benner, E. and Dussault, P. H. and Keiser, J.. (2012) In vitro and in vivo activity of 3-alkoxy-1,2-dioxolanes against Schistosoma mansoni. The journal of antimicrobial chemotherapy, Vol. 67, H. 8. pp. 1979-1986. Tritten, L. and Nwosu, U. and Vargas, M. and Keiser, J.. (2012) In vitro and in vivo efficacy of tribendimidine and its metabolites alone and in combination against the hookworms Heligmosomoides bakeri and Ancylostoma ceylanicum. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin, 122 (1). pp. 101-107. Soukhathammavong, P. A. and Sayasone, S. and Phongluxa, K. and Xayaseng, V. and Utzinger, J. and Vounatsou, P. and Hatz, C. and Akkhavong, K. and Keiser, J. and Odermatt, P.. (2012) Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR. PLoS neglected tropical diseases, Vol. 6, H. 1 , e1417. Fürst, T. and Sayasone, S. and Odermatt, P. and Keiser, J. and Utzinger, J.. (2012) Manifestation, diagnosis, and management of foodborne trematodiasis. BMJ : British medical journal, Vol. 344 , e4093. Manneck, T. and Keiser, J. and Müller, J.. (2012) Mefloquine interferes with glycolysis in schistosomula of Schistosoma mansoni via inhibition of enolase. Parasitology, Vol. 139, H. 4. pp. 497-505. Utzinger, J. and Becker, S. L. and Knopp, S. and Blum, J. and Neumayr, A. L. and Keiser, J. and Hatz, C. F.. (2012) Neglected tropical diseases : diagnosis, clinical management, treatment and control. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology, Vol. 142 , w13726. Kirchhofer, C. and Vargas, M. and Huwyler, J. and Keiser, J.. (2012) Pharmacokinetics of the fasciocidal drug candidates MT04 and OZ78 in uninfected rats and in vitro pharmacodynamic studies. International journal for parasitology: drugs and drug resistance, Vol. 2. pp. 121-125. Lochmatter, C. and Schneider, C. L. and Ingram, K. and Keiser, J. and Schifferli, J. A.. (2012) Schistosoma mansoni tetraspanning orphan receptor (SmTOR) : a new vaccine candidate against Schistosomiasis. Clinical and experimental immunology, Vol. 170, H. 3. pp. 342-357. Saric, J. and Want, E. J. and Duthaler, U. and Lewis, M. and Keiser, J. and Schockcor, J. P. and Ross, G. A. and Nicholson, J. K. and Holmes, E. and Tavares, M. F.. (2012) Systematic evaluation of extraction methods for multi-platform based metabotyping : application to the Fasciola hepatica metabolome. Analytical chemistry, Vol. 84, H. 16. pp. 6963-6972. Toyang, N. J. and Ateh, E. N. and Keiser, J. and Vargas, M. and Bach, H. and Tane, P. and Sondengam, L. B. and Davis, H. and Bryant, J. and Verpoorte, R.. (2012) Toxicity, antimicrobial and anthelmintic activities of Vernonia guineensis Benth. (Asteraceae) crude extracts. Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs, Vol. 144, H. 3. pp. 700-704. Fürst, T. and Duthaler, U. and Sripa, B. and Utzinger, J. and Keiser, J.. (2012) Trematode infections : liver and lung flukes. Infectious disease clinics of North America, Vol. 26, H. 2. pp. 399-419. Zumla, A. and Keiser, J.. (2012) Tropical diseases. Infectious disease clinics of North America, Vol. 26, H. 2 , xv-xvii. 2011Kirchhofer, C. and Vargas, M. and Braissant, O. and Dong, Y. and Wang, X. and Vennerstrom, J. L. and Keiser, J.. (2011) Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni. Acta tropica : Zeitschrift für Tropenwissenschaften und Tropenmedizin, 118 (1). pp. 56-62. Li, J. V. and Saric, J. and Wang, Y. and Keiser, J. and Utzinger, J. and Holmes, E.. (2011) Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. Parasites and Vectors, 4 (179). Keiser, J. and Sayed, H. and El-Ghanam M., and Sabry, H. and Anani, S. and El-Wakeel A., and Hatz, C. and Utzinger, J. and El-Din S. S., and El-Maadawy W., and Botros, S.. (2011) Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials. PLoS neglected tropical diseases, Vol. 5, H. 9 , e1285. Soukhathammavong, P. and Odermatt, P. and Sayasone, S. and Vonghachack, Y. and Vounatsou, P. and Hatz, C. and Akkhavong, K. and Keiser, J.. (2011) Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini : a randomised, exploratory, open-label, phase 2 trial. The Lancet infectious diseases, 11 (2). pp. 110-118. Utzinger, J. and N'Goran E. K., and Caffrey, C. R. and Keiser, J.. (2011) From innovation to application: social-ecological context, diagnostics, drugs and integrated control of schistosomiasis. Acta tropica, 120 (1). S121-S137. Keiser, J. and Ingram, K. and Vargas, M. and Chollet, J. and Wang, X. and Dong, Y. and Vennerstrom, J. L.. (2011) In Vivo Activity of Aryl Ozonides against Schistosoma Species. Antimicrobial agents and chemotherapy, 56 (2). pp. 1090-1092. Küster, T. and Stadelmann, B. and Hermann, C. and Scholl, S. and Keiser, J. and Hemphill, A.. (2011) In vitro and in vivo efficacy of mefloquine-based treatment against alveolar echinococcosis. Antimicrobial agents and chemotherapy : AAC, Vol. 55, H. 2. pp. 713-721. Ferreira, J. F. and Peaden, P. and Keiser, J.. (2011) In vitro trematocidal effects of crude alcoholic extracts of Artemisia annua, A. absinthium, Asimina triloba, and Fumaria officinalis : trematocidal plant alcoholic extracts. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 109, H. 6. pp. 1585-1592. Keiser, J. and Manneck, T. and Vargas, M.. (2011) Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro. The journal of antimicrobial chemotherapy, Vol. 66, H. 8. pp. 1791-1797. Manneck, T. and Braissant, O. and Haggenmüller, Y. and Keiser, J.. (2011) Isothermal microcalorimetry to study drugs against Schistosoma mansoni. Journal of clinical microbiology, Vol. 49, H. 4. pp. 1217-1225. Olliaro, P. and Seiler, J. and Kuesel, A. and Horton, J. and Clark, J. N. and Don, R. and Keiser, J.. (2011) Potential drug development candidates for human soil-transmitted helminthiases. PLoS neglected tropical diseases, Vol. 5, H. 6 , e1138. Manneck, T. and Braissant, O. and Ellis, W. and Keiser, J.. (2011) Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. Experimental parasitology : EP, Vol. 127, H. 1. pp. 260-269. Jones, M. K. and Keiser, J. and McManus, D. P.. (2011) Trematodes. In: Manual of clinical microbiology, 2. Washington, pp. 2230-2242. 2010Keiser, J. and Vargas, M. and Vennerstrom, J. L.. (2010) Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice. The journal of antimicrobial chemotherapy, Vol. 65, H. 9. pp. 1991-1995. Wang, Y. and Li, J. V. and Saric, J. and Keiser, J. and Wu, J. and Utzinger, J. and Holmes, E.. (2010) Advances in metabolic profiling of experimental nematode and trematode infections. Advances in parasitology, Vol. 73. pp. 373-404. Kirchhofer, C. and Keiser, J. and Huwyler, J.. (2010) Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate. Journal of chromatography B, 878 (28). pp. 2770-2774. Keiser, J. and N'Guessan N. A., and Adoubryn, K. D. and Silué, K. D. and Vounatsou, P. and Hatz, C. and Utzinger, J. and N'Goran E. K., . (2010) Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial. Clinical Infectious Diseases, Vol. 50, H. 9. pp. 1205-1213. Duthaler, U. and Rinaldi, L. and Maurelli, M. P. and Vargas, M. and Utzinger, J. and Cringoli, G. and Keiser, J.. (2010) Fasciola hepatica: comparison of the sedimentation and FLOTAC techniques for the detection and quantification of faecal egg counts in rats. Experimental parasitology : EP, Vol. 126, H. 2. pp. 161-166. Utzinger, J. and Steinmann, P. and Keiser, J. and Bos, R.. (2010) Impacts santaires du développement des larges réserves d'eau, barrages et irrigation. In: Écologie de la santé et biodiversité : cours. Bruxelles, pp. 116-125. Keiser, J.. (2010) In vitro and in vivo trematode models for chemotherapeutic studies. Parasitology, 137 (3). pp. 589-603. Duthaler, U. and Smith, T. A. and Keiser, J.. (2010) In vivo and in vitro sensitivity of Fasciola hepatica to combinations of triclabendazole and artesunate, artemether or OZ78. Antimicrobial agents and chemotherapy : AAC, Vol. 54, H. 11. pp. 4596-4604. Manneck, T. and Haggenmüller, Y. and Keiser, J.. (2010) Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni. Parasitology, Vol. 137, H. 1. pp. 85-98. Rufener, L. and Keiser, J. and Kaminsky, R. and Mäser, P. and Nilsson, D.. (2010) Phylogenomics of ligand-gated ion channels predicts monepantel effect. PLoS Pathogens, Vol. 6, H. 9 , e1001091. Dong, Y. and Chollet, J. and Vargas, M. and Mansour, N. R. and Bickle, Q. and Alnouti, Y. and Huang, J. and Keiser, J. and Vennerstrom, J. L.. (2010) Praziquantel analogs with activity against juvenile Schistosoma mansoni. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 20, H. 8. pp. 2481-2484. Xiao, S. H. and Keiser, J. and Chen, M. G. and Tanner, M. and Utzinger, J.. (2010) Research and development of antischistosomal drugs in the People's Republic of China a 60-year review. Advances in parasitology, Vol. 73. pp. 231-295. Utzinger, J. and Keiser, J. and Albonico, M.. (2010) This wormy world : here and there and everywhere. Parassitologia : organo ufficiale della Società Italiana di Parassitologia, Vol. 52. pp. 47-50. 2009Hodel, E. M. and Zanolari, B. and Mercier, T. and Biollaz, J. and Keiser, J. and Olliaro, P. and Genton, B. and Decosterd, L. A.. (2009) A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, Vol. 877, H. 10. pp. 867-886. O'Neill J. F., and Johnston, R. C. and Halferty, L. and Brennan, G. P. and Keiser, J. and Fairweather, I.. (2009) Adult triclabendazole-resistant Fasciola hepatica: morphological changes in the tegument and gut following in vivo treatment with artemether in the rat model. Journal of Helminthology, Vol. 83, H. 2. pp. 151-163. Caffrey, C. R. and Williams, D. L. and Todd, M. J. and Nelson, D. L. and Keiser, J. and Utzinger, J. and Selzer, P. M.. (2009) Chemotherapeutic development strategies for schistosomiasis. In: Antiparasitic and Antibacterial drug discovery. Weinheim, pp. 301-321. Keiser, J. and Odermatt, P. and Tesana, S.. (2009) Dose-response relationships and tegumental surface alterations in Opisthorchis viverrini following treatment with mefloquine in vivo and in vitro. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 105, H. 1. pp. 261-266. Tchicaya, E. S. and Koudou, B. G. and Keiser, J. and Adja, A. M. and Cissé, G. and Tanner, M. and Tano, Y. and Utzinger, J.. (2009) Effect of repeated application of microbial larvicides on malaria transmission in central Côte d'Ivoire. Journal of the American mosquito control association : mosquito news, Vol. 25, H. 3. pp. 382-385. Kim, T. I. and Yoo, W. G. and Li, S. and Hong, S. T. and Keiser, J. and Hong, S. J.. (2009) Efficacy of artesunate and artemether against Clonorchis sinensis in rabbits. Parasitology research : Organ der Deutschen Gesellschaft für Parasitologie, Vol. 106. pp. 153-160. Halferty, L. and O'Neill, J. F. and Brennan, G. P. and Keiser, J. and Fairweather, I.. (2009) Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica. Parasitology, Vol. 136, H. 11. pp. 1325-1337. Keiser, J. and Utzinger, J.. (2009) Food-borne trematodiases. Clinical microbiology reviews, Vol. 22. pp. 466-483. Keiser, J. and Chollet, J. and Xiao, S. H. and Mei, J. Y. and Jiao, P. Y. and Utzinger, J. and Tanner, M.. (2009) Mefloquine - an aminoalcohol with promising antischistosomal properties in mice. PLoS neglected tropical diseases, Vol. 3, H. 1 , e350. Lovis, L. and Mak, T. K. and Phongluxa, K. and Soukhathammavong, P. and Sayasone, S. and Akkhavong, K. and Odermatt, P. and Keiser, J. and Felger, I.. (2009) PCR diagnosis of Opisthorchis viverrini and Haplorchis taichui infections in a Lao community in an area of endemicity and comparison of diagnostic methods for parasitological field surveys. Journal of Clinical Microbiology, Vol. 47, H. 5. pp. 1517-1523. Saric, J. and Li, J. V. and Wang, Y. and Keiser, J. and Veselkov, K. A. and Dirnhofer, S. and Yap, I. K. and Nicholson, J. K. and Holmes, E. and Utzinger, J.. (2009) Panorganismal metabolic response modelling of an experimental Echinostoma caproni infection in the mouse. Journal of Proteome Research, Vol. 8, H. 8. pp. 3899-3911. Erlanger, T. E. and Weiss, S. and Keiser, J. and Utzinger, J. and Wiedenmayer, K.. (2009) Past, present, and future of Japanese encephalitis. Emerging Infectious Diseases, Vol. 15, no. 1 , 7 S.. Keiser, J.. (2009) Vascular pharmacology : opportunities for intervention. Clinical pharmacology and therapeutics, Vol. 86, H. 2. pp. 124-126. 2008Xue, J. and Utzinger, J. and Zhang, Y. N. and Tanner, M. and Keiser, J. and Xiao, S. H.. (2008) Artemether and tribendimidine lack activity in experimental treatment of Paragonimus westermani in the dog. Parasitology research, Vol. 102, H. 3. pp. 537-540. Xiao, S. H. and Jian, X. and Tanner, M. and Yong-Nian, Z. and Keiser, J. and Utzinger, J. and Hui-Qiang, Q.. (2008) Artemether, artesunate, praziquantel and tribendimidine administered singly at different dosages against Clonorchis sinensis : a comparative in vivo study. Acta tropica, 106 (1). pp. 54-59. Erlanger, T. E. and Keiser, J. and Utzinger, J.. (2008) Effect of dengue vector control interventions on entomological parameters in developing countries : a systematic review and meta-analysis. Medical and veterinary entomology, Vol. 22, H. 3. pp. 203-221. Keiser, J. and Rinaldi, L. and Veneziano, V. and Mezzino, L. and Tanner, M. and Utzinger, J. and Cringoli, G.. (2008) Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep. Parasitology research, Vol. 103, H. 3. pp. 517-522. Keiser, J. and Utzinger, J.. (2008) Efficacy of current drugs against soil-transmitted helminth infections : systematic review and meta-analysis. JAMA : the journal of the American Medical Association, Vol. 299, H. 16. pp. 1937-1948. Keiser, J. and Morson, G.. (2008) Fasciola hepatica: Surface tegumental responses to in vitro and in vivo treatment with the experimental fasciolicide OZ78. Experimental parasitology : EP, Vol. 119. pp. 87-93. Keiser, J. and Morson, G.. (2008) Fasciola hepatica: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether. Experimental parasitology : EP, Vol. 118. pp. 228-237. Spicher, M. and Roethlisberger, C. and Lany, C. and Stadelmann, B. and Keiser, J. and Ortega-Mora, L. M. and Gottstein, B. and Hemphill, A.. (2008) In vitro and in vivo treatments of echinococcus protoscoleces and metacestodes with artemisinin and artemisinin derivatives. Antimicrobial agents and chemotherapy, Vol. 52, H. 9. pp. 3447-3450. Saric, J. and Li, J. V. and Wang, Y. and Keiser, J. and Bundy, J. G. and Holmes, E. and Utzinger, J.. (2008) Metabolic Profiling of an Echinostoma caproni Infection in the Mouse for Biomarker Discovery. PLoS Neglected Tropical Diseases, Vol. 2, H. 7 , e254. Keiser, J. and Utzinger, J. and Xiao, S. H. and Odermatt, P. and Tesana, S.. (2008) Opisthorchis viverrini : efficacy and tegumental alterations following administration of tribendimidine in vivo and in vitro. Parasitology research, Vol. 102. pp. 771-776. Saric, J. and Wang, Y. and Li, J. and Coen, M. and Utzinger, J. and Marchesi, J. R. and Keiser, J. and Veselkov, K. and Lindon, J. C. and Nicholson, J. K. and Holmes, E.. (2008) Species variation in the fecal metabolome gives insight into differential gastrointestinal function. Journal of Proteome Research, Vol. 7, H. 1. pp. 352-360. Keiser, J. and Thiemann, K. and Endriss, Y. and Utzinger, J.. (2008) Strongyloides ratti : In Vitro and In Vivo Activity of Tribendimidine. PLoS neglected tropical diseases, Vol. 2, H. 1 , e136. |
