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Items where Author is "Kaiser, M."

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Number of items: 215.

2023

Sevik Kilicaslan, O. and Cretton, S. and Hausmann, E. and Quirós-Guerrero, L. and Karimou, S. and Kaiser, M. and Mäser, P. and Christen, P. and Cuendet, M.. (2023) Antiprotozoal activity of natural products from Nigerien plants used in folk medicine. Front Pharmacol, 14. p. 1190241.

Seebacher, W. and Kaiser, M. and Mäser, P. and Saf, R. and Pferschy-Wenzig, E. M. and Weis, R.. (2023) Benzyl- and dibenzyl tetrahydropyridinylidene ammonium salts with antiplasmodial and antitrypanosomal activity. Monatshefte fuÌ�r Chemie, 154. pp. 105-114.

Rao, S. P. S. and Gould, M. K. and Noeske, J. and Saldivia, M. and Jumani, R. S. and Ng, P. S. and Rene, O. and Chen, Y. L. and Kaiser, M. and Ritchie, R. and Francisco, A. F. and Johnson, N. and Patra, D. and Cheung, H. and Deniston, C. and Schenk, A. D. and Cortopassi, W. A. and Schmidt, R. S. and Wiedemar, N. and Thomas, B. and Palkar, R. and Ghafar, N. A. and Manoharan, V. and Luu, C. and Gable, J. E. and Wan, K. F. and Myburgh, E. and Mottram, J. C. and Barnes, W. and Walker, J. and Wartchow, C. and Aziz, N. and Osborne, C. and Wagner, J. and Sarko, C. and Kelly, J. M. and Manjunatha, U. H. and Mäser, P. and Jiricek, J. and Lakshminarayana, S. B. and Barrett, M. P. and Diagana, T. T.. (2023) Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380 (6652). pp. 1349-1356.

Kruth, S. and Zimmermann, C. J. M. and Kuhr, K. and HIller, W. and Lütz, S. and Pietruszka, J. and Kaiser, M. and Nett, M.. (2023) Generation of aurachin derivatives by whole-cell biotransformation and evaluation of their antiprotozoal properties. Molecules, 28. p. 1066.

Li, J. and Tajuddeen, N. and Feineis, D. and Mudogo, V. and Kaiser, M. and Seo, E. J. and Efferth, T. and Bringmann, G.. (2023) Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities. Bioorganic & medicinal chemistry letters, 86. p. 129258.

2022

Mousavi, A. and Foroumadi, P. and Emamgholipour, Z. and Mäser, P. and Kaiser, M. and Foroumadi, A.. (2022) 2-(Nitroaryl)-5-substituted-1,3,4-thiadiazole derivatives with antiprotozoal activities: in vitro and in vivo study. Molecules, 27. p. 5559.

Ragu�, L. and Peng, C. C. and Kaiser, M. and Görls, H. and Beemelmanns, C.. (2022) A modular approach to the antifungal sphingofungin family: concise total synthesis of sphingofungin A and C. Angewandte Chemie, 61 (5). e202112616.

Dolensky, J. and Hinteregger, C. and Leitner, A. and Seebacher, W. and Saf, R. and Belaj, F. and Mäser, P. and Kaiser, M. and Weis, R.. (2022) Antiprotozoal activity of azabicyclo-nonanes linked to tetrazole or sulfonamide cores. Molecules, 27 (19). p. 6217.

Ren, R. and Wang, X. and Leas, D. A. and Häberli, C. and Cal, M. and Dong, Y. and Kaiser, M. and Keiser, J. and Vennerstrom, J. L.. (2022) Antischistosomal tetrahydro-γ-carboline sulfonamides. Bioorganic & medicinal chemistry letters, 59. p. 128546.

Majer, T. and Bhattarai, K. and Straetener, J. and Pohlmann, J. and Cahill, P. and Zimmermann, M. O. and Hübner, M. P. and Kaiser, M. and Svenson, J. and Schindler, M. and Brötz-Oesterhelt, H. and Boeckler, F. M. and Gross, H.. (2022) Discovery of Ircinianin Lactones B and C: two new cyclic sesterterpenes from the marine sponge Ircinia wistarii. Mar Drugs, 20 (8). p. 532.

Koester, D. C. and Marx, V. M. and Williams, S. and Jiricek, J. and Dauphinais, M. and René, O. and Miller, S. L. and Zhang, L. and Patra, D. and Chen, Y. L. and Cheung, H. and Gable, J. and Lakshminarayana, S. B. and Osborne, C. and Galarneau, J. R. and Kulkarni, U. and Richmond, W. and Bretz, A. and Xiao, L. and Supek, F. and Wiesmann, C. and Honnappa, S. and Be, C. and Mäser, P. and Kaiser, M. and Ritchie, R. and Barrett, M. P. and Diagana, T. T. and Sarko, C. and Rao, S. P. S.. (2022) Discovery of novel quinoline-based proteasome inhibitors for Human African Trypanosomiasis (HAT). Journal of medicinal chemistry, 65. 11776−11787.

Lombe, B. K. and Winand, L. and Diettrich, J. and Tobermann, M. and Hiller, W. and Kaiser, M. and Nett, M.. (2022) Discovery, biosynthetic origin, and heterologous production of massinidine, an antiplasmodial alkaloid. Organic letters, 24 (15). pp. 2935-2939.

Scheiber, N. and Blaser, G. and Pferschy-Wenzig, E. M. and Kaiser, M. and Mäser, P. and Presser, A.. (2022) Efficient oxidative dearomatisations of substituted phenols using hypervalent iodine (iii) reagents and antiprotozoal evaluation of the resulting cyclohexadienones against T. b. rhodesiense and P. falciparum Strain NF54. Molecules, 27 (19). p. 6559.

Bernhard, S. and Kaiser, M. and Burri, C. and Mäser, P.. (2022) Fexinidazole for human African trypanosomiasis, the fruit of a successful public-private partnership. Diseases, 10 (4). p. 90.

Mabuza, J. M. and Kaiser, M. and Bapela, M. J.. (2022) In vitro antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from Pappea capensis EckI & Zeyh. (Sapindaceae). J Ethnopharmacol, 298. p. 115659.

Sevik Kilicaslan, O. and Cretton, S. and Quiros-Guerrero, L. and Bella, M. A. and Kaiser, M. and Mäser, P. and Ndongo, J. T. and Cuendet, M.. (2022) Isolation and structural elucidation of compounds from Pleiocarpa bicarpellata and their in vitro antiprotozoal activity. Molecules, 27 (7). p. 2200.

Beilstein, S. and El Phil, R. and Sahraoui, S. S. and Scapozza, L. and Kaiser, M. and Mäser, P.. (2022) Laboratory selection of trypanosomatid pathogens for drug resistance. Pharmaceuticals (Basel), 15 (2). p. 135.

Hsu, C. S. and Gonçalves, C. and Tona, V. and Pons, A. and Kaiser, M. and Maulide, N.. (2022) Leveraging electron-deficient iminium intermediates in a general synthesis of valuable amines. Angewandte Chemie, 61 (20). e202115435.

Gaudry, A. and Huber, F. and Nothias, L. F. and Cretton, S. and Kaiser, M. and Wolfender, J. L. and Allard, P. M.. (2022) MEMO: mass spectrometry-based sample vectorization to explore chemodiverse datasets. Front Bioinform, 2. p. 842964.

Hermann, T. and Wallner, R. and Dolensky, J. and Seebacher, W. and Pferschy-Wenzig, E. -M. and Kaiser, M. and Mäser, P. and Weis, R.. (2022) New derivatives of the multi-stage active Malaria Box compound MMV030666 and their antiplasmodial potencies. Pharmaceuticals (Basel), 15 (12). p. 1503.

Hinteregger, C. and Dolensky, J. and Seebacher, W. and Saf, R. and Mäser, P. and Kaiser, M. and Weis, R.. (2022) Synthesis and antiprotozoal activity of azabicyclo-nonane pyrimidine hybrids. Molecules, 28. p. 307.

Sykes, M. L. and Kennedy, E. K. and Read, K. D. and Kaiser, M. and Avery, V. M.. (2022) Temporal and wash-out studies identify medicines for malaria venture pathogen box compounds with fast-acting activity against both Trypanosoma cruzi and Trypanosoma brucei. Microorganisms, 10 (7). p. 1287.

2021

Hochegger, P. and Dolensky, J. and Seebacher, W. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2021) 8-amino-6-methoxyquinoline-tetrazole hybrids: Impact of linkers on antiplasmodial activity. Molecules, 26 (18). p. 5530.

Zhao, L. and Le Chapelain, C. and Brachmann, A. O. and Kaiser, M. and Groll, M. and Bode, H. B.. (2021) Activation, structure, biosynthesis and bioactivity of glidobactin-like proteasome inhibitors from Photorhabdus laumondii. Chembiochem, 22 (9). pp. 1582-1588.

Szabó, L. U. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Antiprotozoal Nor-triterpene alkaloids from Buxus sempervirens L. Antibiotics (Basel), 10 (6). p. 696.

Brand, M. and Wang, L. and Agnello, S. and Gazzola, S. and Gall, F. M. and Raguz, L. and Kaiser, M. and Schmidt, R. S. and Ritschl, A. and Jelk, J. and Hemphill, A. and Mäser, P. and Butikofer, P. and Adams, M. and Riedl, R.. (2021) Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action. Angewandte Chemie, 60 (28). pp. 15613-15621.

Greve, H. L. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Boswellic acids show in vitro activity against Leishmania donovani. Molecules, 26 (12). p. 3651.

Rocha-Hasler, M. and de Oliveira, G. M. and da Gama, A. N. and Fiuza, L. F. A. and Fesser, A. F. and Cal, M. and Rocchetti, R. and Peres, R. B. and Guan, X. L. and Kaiser, M. and Soeiro, M. N. C. and Mäser, P.. (2021) Combination with tomatidine improves the potency of posaconazole against Trypanosoma cruzi. Front Cell Infect Microbiol, 11. p. 617917.

Leas, D. A. and Sanford, A. G. and Wu, J. and Cal, M. and Kaiser, M. and Wittlin, S. and Hemsley, R. M. and Darner, E. B. and Lui, L. M. and Davis, P. H. and Vennerstrom, J. L.. (2021) Diaryl ureas as an antiprotozoal chemotype. ACS Infect Dis, 7 (6). pp. 1578-1583.

Boberg, M. and Cal, M. and Kaiser, M. and Jansson-Lofmark, R. and Mäser, P. and Ashton, M.. (2021) Enantiospecific antitrypanosomal in vitro activity of eflornithine. PLoS Negl Trop Dis, 15 (7). e0009583.

Cretton, S. and Genta-Jouve, G. and Kaiser, M. and Mäser, P. and Muñoz, O. and Bürgi, T. and Cuendet, M. and Christen, P.. (2021) Hygroline derivatives from Schizanthus tricolor and their anti-trypanosomatid and antiplasmodial activities. Phytochemistry, 192. p. 112957.

Szabó, L. U. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Identification of antiprotozoal compounds from Buxus sempervirens L. by PLS-prediction. Molecules, 26 (20). p. 6181.

Brown, R. W. and Abdel-Megeed, A. M. and Keller, P. A. and Jones, A. J. and Sykes, M. L. and Kaiser, M. and Baell, J. B. and Avery, V. M. and Hyland, C. J. T.. (2021) Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness. RSC Medicinal Chemistry, 11 (12). pp. 1413-1422.

Seebacher, W. and Mohsin, N. U. A. and Dolensky, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Saf, R. and Schuster, D. and Temml, V. and Weis, R.. (2021) Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies. Monatshefte fuÌ�r Chemie, 152. pp. 1347-1359.

Winand, L. and Schneider, P. and Kruth, S. and Greven, N.-J- and Hiller, W. and Kaiser, M. and Pietruszka, J. and Nett, M.. (2021) Mutasynthesis of physostigmines in Myxococcus xanthus. Organic letters, 23 (16). pp. 6563-6567.

Fesser, A. and Kaiser, M. and Mäser, P.. (2021) Neue Parameter für die Wirkstofftestung gegen Trypanosoma cruzi. Biospektrum (Heidelb), 27 (2). pp. 168-170.

Hermann, T. and Hochegger, P. and Dolensky, J. and Seebacher, W. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2021) New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities. Pharmaceuticals (Basel), 14 (5). p. 412.

Mahmoud, A. B. and Abd Algaffar, S. and van de Sande, W. and Khalid, S. and Kaiser, M. and Mäser, P.. (2021) Niclosamide is active in vitro against mycetoma pathogens. Molecules, 26 (13). p. 4005.

Llurba Montesino, N. and Kaiser, M. and Mäser, P. and Schmidt, T. J.. (2021) Nucleic acid amplification techniques for the detection of Schistosoma mansoni infection in humans and the intermediate snail host: a structured review and meta-analysis of diagnostic accuracy. Molecules, 26 (11). p. 3226.

Petritsch, M. and Seebacher, W. and Mohsin, N. U. and Dolensky, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Belaj, F. and Saf, R. and Kretschmer, N. and Alajlani, M. and Brantner, A. and Bauer, R. and Schuhly, W. and Weis, R.. (2021) Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. Eur J Med Chem, 210. p. 112969.

Mizukawa, Y. and Ikegami-Kawai, M. and Horiuchi, M. and Kaiser, M. and Kojima, M. and Sakanoue, S. and Miyagi, S. and Nanga Chick, C. and Togashi, H. and Tsubuki, M. and Ihara, M. and Usuki, T. and Itoh, I.. (2021) Quest for a potent antimalarial drug lead: synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines. Bioorganic & medicinal chemistry, 33. p. 116018.

Lombe, B. K. and Feineis, D. and Mudogo, V. and Kaiser, M. and Bringmann, G.. (2021) Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese Ancistrocladus plant. Journal of natural products, 84 (4). pp. 1335-1344.

Uth, J. F. and Borgel, F. and Lehmkuhl, K. and Schepmann, D. and Kaiser, M. and Jabor, V. A. P. and Nonato, M. C. and Krauth-Siegel, R. L. and Schmidt, T. J. and Wunsch, B.. (2021) Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents. Journal of medicinal chemistry, 64 (9). pp. 6397-6409.

Hermann, T. and Hochegger, P. and Dolensky, J. and Seebacher, W. and Pferschy-Wenzig, E. M. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2021) Synthesis and structure-activity relationships of new 2-phenoxybenzamides with antiplasmodial activity. Pharmaceuticals (Basel), 14. p. 1109.

Doganc, F. and Celik, I. and Eren, G. and Kaiser, M. and Brun, R. and Goker, H.. (2021) Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles. European journal of medicinal chemistry, 221. p. 113545.

Flittner, D. and Kaiser, M. and Mäser, P. and Lopes, N. P. and Schmidt, T. J.. (2021) The alkaloid-enriched fraction of; The alkaloid-enriched fraction of Pachysandra terminalis (Buxaceae) shows prominent activity against Trypanosoma brucei rhodesiensePachysandra terminalis; (Buxaceae) shows prominent activity against; Trypanosoma brucei rhodesiense. Molecules, 26 (3). p. 591.

Hoffelner, M. H. and Seebacher, W. and Kaiser, M. and Mäser, P. and Pferschy-Wenzig, E. M. and Saf, R. and Belaj, F. and Kretschmer, N. and Alajlani, M. and Brantner, A. and Bauer, R. and Weis, R.. (2021) Unexpected ring‑opening of 2,3‑dihydropyridines. Monatshefte für Chemie, 152. pp. 1347-1359.

2020

Kaiser, M. and Mäser, P.. (2020) In Vitro drug efficacy testing against Trypanosoma brucei. New York.

Hoffelner, M. and Hassan, U. and Seebacher, W. and Dolensky, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Saf, R. and Weis, R.. (2020) New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities. Monatshefte für Chemie, 151. pp. 1375-1385.

Kalt, M. M. and Schuehly, W. and Saf, R. and Ochensberger, S. and Solnier, J. and Bucar, F. and Kaiser, M. and Presser, A.. (2020) Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents. Eur J Med Chem, 207. p. 112837.

Zhao, L. and Vo, T. D. and Kaiser, M. and Bode, H. B.. (2020) Phototemtide A, a cyclic lipopeptide heterologously expressed from Photorhabdus temperata Meg1, shows selective antiprotozoal activity. ChemBioChem, 21 (9). pp. 1288-1292.

Cretton, S. and Kaiser, M. and Karimou, S. and Ebrahimi, S. N. and Mäser, P. and Cuendet, M. and Christen, P.. (2020) Pyridine-4(1H)-one alkaloids from Waltheria indica as antitrypanosomatid agents. Journal of natural products, 83 (11). pp. 3363-3371.

Babanezhad Harikandei, K. and Salehi, P. and Ebrahimi, S. N. and Bararjanian, M. and Kaiser, M. and Al-Harrasi , A.. (2020) Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives. Bioorganic & medicinal chemistry, 28 (1). p. 115185.

Saldivia, M. and Fang, E. and Ma, X. and Myburgh, E. and Carnielli, JBT. and Bower-Lepts, C. and Brown, E. and Ritchie, R. and Lakshminarayana, SB. and Chen, YL. and Patra, D. and Ornelas, E. and Koh, HXY. and Williams, SL. and Supek, F. and Paape, D. and McCulloch, R. and Kaiser, M. and Barrett, MP. and Jiricek, J. and Diagana, TT. and Mottram, JC. and Rao, SPS.. (2020) Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors. Nat Microbiol, 5 (10). pp. 1207-1216.

Robinson, W. J. and Taylor, A. E. and Lauga-Cami, S. and Weaver, G. W. and Arroo, R. R. J. and Kaiser, M. and Gul, S. and Kuzikov, M. and Ellinger, B. and Singh, K. and Schirmeister, T. and Botana, A. and Eurtivong, C. and Bhambra, A. S.. (2020) The discovery of novel antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines. Eur J Med Chem, 209. p. 112871.

Chung, J. H. and Tang, A. H. and Geraghty, K. and Corcilius, L. and Kaiser, M. and Payne, R.J.. (2020) Total synthesis and antitrypanosomal activity of janadolide and simplified analogues. Organic letters, 22. pp. 3089-3093.

Soroury, S. and Alilou, M. and Gelbrich, T. and Tabefam, M. and Danton, O. and Ebrahimi, S. N. and Kaiser, M. and Hamburger, M. and Stuppner, H. and Moridi Farimani, M.. (2020) Unusual derivatives from Hypericum scabrum. Scientific Reports, 10. p. 22181.

2019

Wang, X. and Cal, M. and Kaiser, M. and Buckner, F. S. and Lepesheva, G. I. and Sanford, A. G. and Wallick, A. I. and Davis, P. H. and Vennerstrom, J. L.. (2019) A new chemotype with promise against Trypanosoma cruzi. Bioorganic & medicinal chemistry letters, 30. p. 126778.

Tasdemir, D. and Kaiser, M. and Demirci, B. and Demirci, F. and Baser, K. H. C.. (2019) Antiprotozoal activity of turkish Origanum onites essential oil and its components. Molecules, 24 (23). p. 4421.

Mufusama, J. P. and Feineis, D. and Mudodo, V. and Kaiser, M. and Brun, R. and Bringmann, G.. (2019) Antiprotozoal dimeric naphthylisoquinolines, mbandakamines B3 and B4, and related 5,80'-coupled monomeric alkaloids, ikelacongolines A-D, from a Congolese Ancistrocladus liana. RSC advances, 9 (21). pp. 12034-12046.

Zhao, L. and Awori, R. M. and Kaiser, M. and Gross, J. and Opatz, T. and Bode, H. B.. (2019) Structure, biosynthesis, and bioactivity of photoditritide from Photorhabdus temperata meg1. Journal of natural products, 82 (12). pp. 3499-3503.

Smeilus, T. and Mousavizadh, F. and Kriger, J. and Tu, X. and Kaiser, M. and Giannis, A.. (2019) Synthesis and biological investigation of (+)-3-hydroxymethylartemisinin. Journal of Organic Chemistry, 15. pp. 567-570.

Mohsin, N. U. A. and Seebacher, W. and Hochegger, P. and Faist, J. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2019) Synthesis of new 1-benzyl tetrahydropyridin-4-ylidene piperidinium salts and their antiplasmodial and antitrypanosomal activities. Medicinal chemistry research, 28 (5). pp. 742-753.

Pérez-Moreno , G. and Sánchez-Carrasco , P. and Ruiz-Pérez , L.M. and Johansson, N. G. and Muller, S. and Baragaña, B. and Hampton, S. E. and Gilbert, I. H. and Kaiser, M. and Sarkar, S. and Pandurangan, T. and Kumar, V. and Gonzalez-Pacanowska , D.. (2019) Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity. Malaria journal, 18. p. 392.

2018

Tabefam, M. and Farimani, M. M. and Danton, O. and Ramseyer, J. and Ebrahimi, S. N. and Neuburger, M. and Kaiser, M. and Salehi, P. and Potterat, O. and Hamburger, M.. (2018) Antiprotozoal isoprenoids from Salvia hydrangea. Journal of natural products, 81. pp. 2682-2691.

Schies, C. and Seupel, R. and Feineis, D. and Gehrold, A. and Schraut, M. and Kaiser, M. and Brun, R. and Bringmann, G.. (2018) Biomimetic total synthesis of mbandakamine A and further antiplasmodial naphthylisoquinoline dimers. ChemistrySelect, 3. pp. 940-945.

Guo, H. and Benndorf, R. and Konig, S. and Leichnitz, D. and Weigel, C. and Peschel, G. and Berthel, P. and Kaiser, M. and Steinbeck, C. and Werz, O. and Pulsen, M. and Beemelmanns, C.. (2018) Expanding the rubterolone Family : intrinsic reactivity and directed diversification of PKS-derived pyrans. Chemistry - A European Journal, 24 (44). pp. 11319-11324.

Shi, Y. M. and Richter, C. and Challinor, V. L. and Grun, P. Girela Del Rio and Kaiser, M. and Schuffler, A. and Piepenbring, M. and Schwalbe, H. and Bode, H. B.. (2018) Georatusin, a specific antiparasitic polyketide-peptide hybrid from the gungus Geomyces auratus. Organic Letters, 20 (6). pp. 1563-1567.

Mohsin, N. U. A. and Seebacher, W. and Faist, J. and Kretschmer, N. and Bauer, R. and Saf, R. and Kaiser, M. and Mäser, P. and Weis, R.. (2018) Modifications on tetrahydropyridin-4-ylidene ammonium salts and their antiprotozoal activities. Monatshefte für Chemie, 149 (4). pp. 801-812.

Mohsin, N. U. A. and Seebacher, W. and Faist, J. and Hochegger, P. and Kaiser, M. and Mäser, P. and Saf, R. and Weis, R.. (2018) The antiplasmodial and antitrypanosomal activities of novel piperazine derivatives of 3-azabicyclo[3.2.2]nonanes. Monatshefte für Chemie, 149 (1). pp. 99-109.

2017

De Mieri, M. and Smiesko, M. and Ismajili, I. and Kaiser, M. and Hamburger, M.. (2017) Acid-induced rearrangement of epoxygermacranolides: synthesis of furanoheliangolides and cadinanes from nobilin. Molecules, 22 (12). E2252.

Bapela, M. J. and Kaiser, M. and Meyer, J. J. M.. (2017) Antileishmanial activity of selected South African plant species. South African journal of botany, 108. pp. 342-345.

Greve, H. L. and Kaiser, M. and Brun, R. and Schmidt, Tj. (2017) Erratum: terpenoids from the oleo-gum-resin of boswellia serrata and their antiplasmodial effects in vitro. Planta medica, 83 (14-15). E4.

Dawidowski, M. and Emmanouilidis, L. and Kalel, V. C. and Tripsianes, K. and Schorpp, K. and Hadian, K. and Kaiser, M. and Mäser, P. and Kolonko, M. and Tanghe, S. and Rodriguez, A. and Schliebs, W. and Erdmann, R. and Sattler, M. and Popowicz, G. M.. (2017) Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science, 355 (6332). pp. 1416-1420.

Ndjakou Lenta, B. and Ngatchou, J. and Frese, M. and Ladoh-Yemeda, F. and Nardella, F. and Michalek, C. and Wibberg, D. and Ngouela, S. and Tsamo, E. and Kaiser, M. and Kalinowski, J. and Sewald, N.. (2017) Purpureone, an antileishmanial ergochrome from the endophytic fungus Purpureocillium lilacinum. Zeitschrift für Naturforschung. Sect. B, Chemical sciences, 71 (11). pp. 1159-1167.

Seebacher, W. and Belaj, F. and Faist, J. and Saf, R. and Bucar, F. and Turek, I. and Branter, A. and Alajlani, M. and Kaiser, M. and Mäser, P. and Weis, R.. (2017) Synthesis of new pyrido-benzodiazepine salts and their antimicrobial activities. Monatshefte für Chemie, 148 (2). pp. 263-274.

Kuzma, Ł and Kaiser, M. and Wysokińska, H.. (2017) The production and antiprotozoal activity of abietane diterpenes in Salvia austriaca hairy roots grown in shake flasks and bioreactor. Preparative biochemistry, 47 (1). pp. 58-66.

2016

Vanden Eynde, J. J. and Mayence, A. and Mottamal, M. and Bacchi, C. J. and Yarlett, N. and Kaiser, M. and Brun, R. and Huang, T. L.. (2016) Alkanediamide-linked bisbenzamidines are promising antiparasitic agents. Pharmaceuticals, 9 (2). pp. 1-11.

Vahermo, M. and Krogerus, S. and Nasereddin, A. and Kaiser, M. and Brun, R. and Jaffe, C. L. and Yli-Kauhaluoma, J. and Moreira, V. M.. (2016) Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania denovani and Trypanosoma cruzi. MedChemComm, 7 (3). pp. 457-463.

Mir Mohseni, M. and Hover, T. and Barra, L. and Kaiser, M. and Dorrestein, P. C. and Dickschat, J. S. and Schaberle, T. F.. (2016) Discovery of a mosaic-like biosynthetic assembly line with a decarboxylative off-loading mechanism through a combination of genome mining and imaging. Angewandte Chemie. International edition in English, 55 (43). pp. 13611-13614.

Faist, J. and Seebacher, W. and Saf, R. and Brun, R. and Kaiser, M. and Weis, R.. (2016) New derivatives of bicyclic diamines with antiprotozoal activity. Monatshefte für Chemie, 147 (2). pp. 369-381.

Wolkinger, V. and Ahmad, S. and Seebacher, W. and Faist, J. and Saf, R. and Kaiser, M. and Brun, R. and Weis, R.. (2016) New diaryl-substituted azabicyclo[3.2.2]nonanes and their antiprotozoal potencies. Monatshefte für Chemie, 147 (10). pp. 1721-1735.

2015

De Mieri, M. and Kaiser, M. and Brun, R. and Thormann, U. and Imanidis, G. and Hamburger, M.. (2015) Anti-trypanosomal cadinanes synthesized by transannular cyclization of the natural sesquiterpene lactone nobilin. Bioorganic & medicinal chemistry, 23 (7). pp. 1521-1529.

Shaban, E. and Wicht, K. J. and Wang, N. and Mei, Z. W. and Hayashi, I. and El Gokha, A. A. A. and Kaiser, M. and El Sayed, I. E. and Egan, T. J. and Inokuchi, T.. (2015) Synthesis and antimalarial activity of some neocryptolepine analogues carrying a multifunctional linear and branched carbon-side chains. Heterocycles, Vol. 89, H. 4. pp. 1055-1064.

Manos-Turvey, A. and Watson, E. E. and Sykes, M. L. and Jones, A. J. and Baell, J. B. and Kaiser, M. and Avery, V. M. and Payne, R. J.. (2015) Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. MedChemComm, Vol. 6, H. 3. pp. 403-406.

Seebacher, W. and Faist, J. and Belaj, F. and Saf, R. and Kaiser, M. and Brun, R. and Weis, R.. (2015) Synthesis of new tetrahydropyridinylidene ammonium salts and their antprotozoal potency. Monatshefte für Chemie, 146 (8). pp. 1299-1308.

2014

Hanna, J. N. and Ntie-Kang, F. and Kaiser, M. and Brun, R. and Efange, S. M. N.. (2014) 1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials : synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics evaluation. RSC advances, Vol. 4, H. 44 ,22856-22865.

Weis, R. and Seebacher, W. and Brun, R. and Kaiser, M. and Saf, R. and Faist, J.. (2014) 4-Aminobicyclo[2.2.2]octan-2-yl 4-aminobutanoates with antiprotozoal activity. Monatshefte für Chemie, Vol. 145, H. 2. pp. 311-317.

Usuki, T. and Sato, M. and Hara, S. and Yoshimoto, Y. and Kondo, R. and Zimmermann, S. and Kaiser, M. and Brun, R. and Hamburger, M. and Adams, M.. (2014) Antitrypanosomal structure-activity-relationship study of semisynthetic cynaropicrin derivatives. Bioorganic and Medicinal Chemistry Letters, 24 (3). pp. 794-798.

Dandapani, S. and Germain, A. R. and Jewett, I. and Le Quement, S. and Marie, JC. and Muncipinto, G. and Duvall, J. R. and Carmody, L. C. and Perez, J. R. and Engel, J. C. and Gut, J. and Kellar, D. and Siqueira-Neto, J. L. and McKerrow, J. H. and Kaiser, M. and Rodriquez, A. and Palmer, M. A. and Foley, M. and Schreiber, S. L. and Munoz, B.. (2014) Diversity-oriented synthesis yields a new drug lead for treatment of Chagas disease. ACS medicinal chemistry letters, Vol. 5, H. 2. pp. 149-153.

Kronenwerth, M. and Dauth, C. and Kaiser, M. and Pemberton, I. and Bode, H. B.. (2014) Facile synthesis of cyclohexanediones and dialkylresorcinols : bioactive natural products from entomopathogenic bacteria. European journal of organic chemistry, H. 36. pp. 8026-8028.

Hata, Y. and de Mieri, M. and Ebrahimi, S. N. and Mokoka, T. and Fouche, G. and Kaiser, M. and Brun, R. and Potterat, O. and Hamburger, M.. (2014) Identification of two new phenanthrenones and a saponin as antiprotozoal constituents of Drypetes gerrardii. Phytochemistry letters, Vol. 10. pp. 133-140.

Hata, Y. and De Mieri, M. and Ebrahimi, S. N. and Mokoka, T. and Fouche, G. and Kaiser, M. and Brun, R. and Potterat, O. and Hamburger, M.. (2014) Identification of two new phenathrenones and a saponin as antiprotozoal constituents of Drypetes gerrardii. Phytochemistry letters, Vol. 10. pp. 133-140.

Ngamgwe, R. F. and Yankam, R. and Chouna, J. R. and Lanz, C. and Furrer, J. and Schürch, S. and Kaiser, M. and Lenta, B. N. and Ngouela, S. and Tsamo, E. and Brenneisen, R.. (2014) Procerenone: a Fatty Acid Triterpenoid from the Fruit Pericarp of Omphalocarpum procerum (Sapotaceae). Iranian Journal of Pharmaceutical Research, 13 (4). pp. 1425-1430.

Zimmermann, S. and Fouche, G. and de Mieri, M. and Yoshimoto, Y. and Usuki, R. and Nthambeleni, R. and van der Westhuyzen, C. and Kaiser, M. and Hamburger, M. and Adams, M.. (2014) Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products. Molecules, 19 (3). pp. 3523-3538.

Wang, N. and Wicht, K. J. and Shaban, E. and Ngoc, T. A. and Wang, M. Q. and Hayashi, I. and Hossain, M. I. and Takemasa, Y. and Kaiser, M. and El Sayed, I. E. T. and Egan, T. J. and Inokuchi, T.. (2014) Synthesis and evaluation of artesunate-indoloquinoline hybrids as antimalarial drug candidates. MedChemComm : Medicinal chemistry communications, Vol. 5, H. 7. pp. 927-931.

Mohsin, N. U. A. and Seebacher, W. and Faist, J. and Belaj, F. and Saf, R. and Kaiser, M. and Brun, R. and Weis, R.. (2014) Synthesis of antiprotozoal diamines by regioselective insertion of nitrogen into a bicyclic ring system. Monatshefte für Chemie, Vol. 145, H. 8. pp. 1319-1327.

2013

McKeever, C. and Kaiser, M. and Rozas, I.. (2013) Aminoalkyl derivatives of guanidine di-aromatic minor groove binders with antiprotozoal activity. Journal of medicinal chemistry, 56 (3). pp. 700-711.

Mokoka, Tsholofelo A. and Xolani, Peter K. and Zimmermann, S. and Hata, Y. and Adams, M. and Kaiser, M. and Moodley, N. and Maharaj, Y. and Koorbanally, Neil A. and Hamburger, M. and Brun, R. and Fouche, G.. (2013) Antiprotozoal Screening of 60 South African Plants, and the Identification of the Antitrypanosomal Germacranolides Schkuhrin I and II. Planta medica, Vol. 79, H. 14. pp. 1380-1384.

Liew, L. P. P. and Kaiser, M. and Copp, B. R.. (2013) Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 23, H. 2. pp. 452-454.

Murugesan, D. and Mital, A. and Kaiser, M. and Shackleford, D. M. and Morizzi, J. and Katneni, K. and Campbell, M. and Hudson, A. and Charman, S. A. and Yeates, C. and Gilbert, I. H.. (2013) Discovery and structure-activity relationships of pyrrolone antimalarials. Journal of medicinal chemistry, 56 (7). pp. 2975-2990.

Molette, J. and Routier, J. and Abla, N. and Besson, D. and Bombrun, A. and Brun, R. and Burt, H. and Georgi, K. and Kaiser, M. and Nwaka, S. and Muzerelle, M. and Scheer, A.. (2013) Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties. ACS medicinal chemistry letters, Vol. 4, H. 11. pp. 1037-1041.

Friggeri, L. and Scipione, L. and Costi, R. and Kaiser, M. and Moraca, F. and Zamperini, C. and Botta, B. and Di Santo, R. and De Vita, D. and Brun, R. and Tortorella, S.. (2013) New promising compounds with in vitro nanomolar activity against Trypanosoma cruzi. ACS medicinal chemistry letters, Vol. 4, H. 6. pp. 538-541.

Hwang, J. Y. and Smithson, S. C. and Zhu, F. and Holbrook, G. and Connelly, M. C. and Kaiser, M. and Brun, R. and Guy, R. K.. (2013) Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for Human African Trypanosomiasis (HAT). Journal of medicinal chemistry, 56 (7). pp. 2850-2860.

Grundmann, F. and Kaiser, M. and Kurz, M. and Schiell, M. and Batzer, A. and Bode, H. B.. (2013) Structure determination of the bioactive depsipeptide xenobactin from Xenorhabdus sp. PB30.3. RSC advances, Vol. 3, H. 44. pp. 22072-22077.

Wang, N. and Wicht, K. J. and Wang, L. and Lu, W. J. and Misumi, R. and Wang, M. Q. and El Gokha, A. A. and Kaiser, M. and El Sayed, T. and Egan, T. J. and Inokuchi, T.. (2013) Synthesis and in vitro testing of antimalarial activity of non-natural-type neocryptolepines : structure-activity relationship study of 2,11- and 9,11-disubstituted 6-methylindolo[2,3-b]quinolines. Chemical and pharmaceutical bulletin, Vol. 61, H. 12. pp. 1282-1290.

Bruno, M. and Trucchi, B. and Monti, D. and Romeo, S. and Kaiser, M. and Verotta, L.. (2013) Synthesis of a potent antimalarial agent through natural products conjugation. ChemMedChem : chemistry enabling drug discovery, Vol. 8, H. 2. pp. 221-225.

Dürüst, Y. and Altug, C. and Kaiser, M. and Fronczek, F. R. and Tasdemir, D.. (2013) Synthesis, crystal structure, and in vitro antiprotozoal activity of some 5-phenyl(methyl)sulfonyl-substituted dihydroisoxazoles. Monatshefte für Chemie, Vol. 144, H. 5. pp. 707-716.

2012

Gökbulut, A. and Kaiser, M. and Brun, R. and Sarer, E. and Schmidt, T. J.. (2012) 9β-hydroxyparthenolide esters from Inula montbretiana and their antiprotozoal activity. Planta medica, Vol. 78, H. 3. pp. 225-229.

Witschel, M. and Rottmann, M. and Kaiser, M. and Brun, R.. (2012) Agrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas disease. PLoS neglected tropical diseases, Vol. 6, H. 10 , e1805.

Mäser, P. and Wittlin, S. and Rottmann, M. and Wenzler, T. and Kaiser, M. and Brun, R.. (2012) Antiparasitic agents : new drugs on the horizon. Current opinion in pharmacology, Vol. 12, H. 5. pp. 562-566.

Lizzi, F. and Veronesi, G. and Belluti, F. and Bergamini, C. and Lopez-Sanchez, A. and Kaiser, M. and Brun, R. and Krauth-Siegel, R. L. and Hall, D. and Rivas, L. and Bolognesi, M. L.. (2012) Conjugation of quinones with natural polyamines : towards an expanded anti-trypanosomatid profile. Journal of medicinal chemistry, 55 (23). pp. 10490-10500.

Zimmermann, S. and Kaiser, M. and Brun, R. and Hamburger, M. and Adams, M.. (2012) Cynaropicrin : the first natural product with in vivo activity against Trypanosoma bruce rhodesiense. Planta medica, Vol. 78, H. 6. pp. 553-556.

Carvalho, S. A. and Feitosa, L. O. and Soares, M. and Costa, T. E. and Henriques, M. G. and Salomao, K. and de Castro, S. L. and Kaiser, M. and Brun, R. and Wardell, J. L. and Wardell, S. M. and Trossini, G. H. and Andricopulo, A. D. and da Silva, E. F. and Fraga, C. A.. (2012) Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents. European journal of medicinal chemistry, 54. pp. 512-521.

Ahmad, S. and Weis, R. and Faist, J. and Wolkinger, V. and Saf, R. and Belaj, F. and Brun, R. and Kaiser, M. and Seebacher, W.. (2012) Diarylcyclohexanones : synthons for new bicyclic compounds. Monatshefte für Chemie, Vol. 143, H. 1. pp. 145-152.

Arán, V. J. and Kaiser, M. and Dardonville, C.. (2012) Discovery of nitroheterocycles active against African trypanosomes : in vitro screening and preliminary SAR studies. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 22, H. 14. pp. 4506-4516.

Dastan, D. and Salehi, P. and Gohari, A. R. and Ebrahimi, S. N. and Zimmermann, S. and Kaiser, M. and Hamburger, M. and Khavasi, H. R.. (2012) Disesquiterpene and sesquiterpene coumarins from Ferula pseudalliacea, and determination of their absolute configurations. Phytochemistry, 78. pp. 170-178.

Mombelli, P. and Witschel, M. C. and van Zijl, A. W. and Geist, J. G. and Rottmann, M. and Freymond, C. and Röhl, F. and Kaiser, M. and Illarionova, V. and Fischer, M. and Siepe, I. and Schweizer, W. B. and Brun, R. and Diederich, F.. (2012) Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates. ChemMedChem, Vol. 7, H. 1. pp. 151-158.

Brunner, R. and Aissaoui, H. and Boss, C. and Bozdech, Z. and Brun, R. and Corminboeuf, O. and Delahaye, S. and Fischli, C. and Heidmann, B. and Kaiser, M. and Kamber, J. and Meyer, S. and Papastogiannidis, P. and Siegrist, R. and Voss, Till S. and Welford, R. and Wittlin, S. and Binkert, C.. (2012) Identification of a new chemical class of antimalarials. Journal of infectious diseases, Vol. 206, no. 5. pp. 735-743.

Sykes, M. L. and Baell, J. B. and Kaiser, M. and Chatelain, E. and Moawad, S. R. and Ganame, D. and Ioset, J. R. and Avery, V. M.. (2012) Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign. PLoS neglected tropical diseases, Vol. 6, H. 11 , e1896.

Attioua, B. and Yeo, D. and Lagnika, L. and Harisolo, R. and Antheaume, C. and Weniger, B. and Kaiser, M. and Lobstein, A. and Vonthron-Sénécheau, C.. (2012) In vitro antileishmanial, antiplasmodial and cytotoxic activities of a new ventiloquinone and five known triterpenes from Parinari excelsa. Pharmaceutical biology, Vol. 50, H. 7. pp. 801-806.

Schmidt, T. J. and Rzeppa, S. and Kaiser, M. and Brun, R.. (2012) Larrea tridentata - absolute configuration of its epoxylignans and investigations on its antiprotozoal activity. Phytochemistry letters, Vol. 5, H. 3. pp. 632-637.

Chianese, G. and Fattorusso, E. and Scala, F. and Teta, R. and Calcinai, B. and Bavestrello, G. and Dien, H. A. and Kaiser, M. and Tasdemir, D. and Taglialatela-Scafati, O.. (2012) Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin. Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry, Vol. 10, H. 35. pp. 7197-7207.

Faist, J. and Seebacher, W. and Saf, R. and Brun, R. and Kaiser, M. and Weis, R.. (2012) New N-methylpiperazinyl derivatives of bicyclic antiprotozoal compounds. European journal of medicinal chemistry, 47 (1). pp. 510-519.

Zimmermann, S. and Thomi, S. and Kaiser, M. and Hamburger, M. and Adams, M.. (2012) Screening and HPLC-based activity profiling for new antiprotozoal leads from European plants. Scientia Pharmaceutica, 80 (1). pp. 205-213.

Dürüst, Y. and Karakus, H. and Kaiser, M. and Tasdemir, D.. (2012) Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles. European journal of medicinal chemistry, 48. pp. 296-304.

McCracken, S. T. and Kaiser, M. and Boshoff, H. I. and Boyd, P. D. and Copp, B. R.. (2012) Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 20 (4). pp. 1482-1493.

Taladriz, A. and Healy, A. and Flores, Perez and Herrero, Garcia and Rios, Martinez and Alkhaldi, A. A. and Eze, A. A. and Kaiser, M. and de Koning, H. P. and Chana, A. and Dardonville, C.. (2012) Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes. Journal of medicinal chemistry, 55 (6). pp. 2606-2622.

Hiltensperger, G. and Jones, N. G. and Niedermeier, S. and Stich, A. and Kaiser, M. and Jung, J. and Puhl, S. and Damme, A. and Braunschweig, H. and Meinel, L. and Engstler, M. and Holzgrabe, U.. (2012) Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei. Journal of medicinal chemistry, 55 (6). pp. 2538-2548.

Ge, J. F. and Zhang, Q. Q. and Lu, J. M. and Kaiser, M. and Brun, R. and Ihara, M.. (2012) Synthesis of cyanine dyes and investigation of their in vitro antiprotozoal activities. MedChemComm, Vol. 3, H. 11. pp. 1435-1442.

Stec, J. and Huang, Q. and Pieroni, M. and Kaiser, M. and Fomovska, A. and Mui, E. and Witola, W. H. and Bettis, S. and McLeod, R. and Brun, R. and Kozikowski, A. P.. (2012) Synthesis, biological evaluation and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania. Journal of medicinal chemistry, 55 (7). pp. 3088-3100.

2011

Bourdin Trunz B., and Jedrysiak, R. and Tweats, D. and Brun, R. and Kaiser, M. and Suwinski, J. and Torreele, E.. (2011) 1-aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis. European journal of medicinal chemistry, 46 (5). pp. 1524-1535.

Maas, M. and Hensel, A. and Batista da Costa F., and Brun, R. and Kaiser, M. and Schmidt, T. J.. (2011) An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatorium perfoliatum. Phytochemistry : an international journal of plant biochemistry, Vol. 72, H. 7. pp. 635-644.

Chan, S. T. and Pearce, A. N. and Januario, A. H. and Page, M. J. and Kaiser, M. and McLaughlin, R. J. and Harper, J. L. and Webb, V. L. and Barker, D. and Copp, B. R.. (2011) Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum. The journal of organic chemistry, Vol. 76, H. 21. pp. 9151-9160.

Kaiser, M. and Bray, M. A. and Cal, M. and Trunz, B. B. and Torreele, E. and Brun, R.. (2011) Anti-trypanosomal activity of Fexinidazole: a new oral nitroimidazole drug candidate for the treatment of sleeping sickness. Antimicrobial agents and chemotherapy : AAC, Vol. 55, H. 12. pp. 5602-5608.

Ndakala, A. J. and Gessner, R. K. and Gitari, P. W. and October, N. and White, K. L. and Hudson, A. and Fakorede, F. and Shackleford, D. M. and Kaiser, M. and Yeates, C. and Charman, S. A. and Chibale, K.. (2011) Antimalarial Pyrido[1,2-a]benzimidazoles. Journal of medicinal chemistry, 54 (13). pp. 4581-4589.

Chan, S. T. and Pearce, A. N. and Page, M. J. and Kaiser, M. and Copp, B. R.. (2011) Antimalarial beta-carbolines from the New Zealand ascidian Pseudodistoma opacum. Journal of natural products, Vol. 74, H. 9. pp. 1972-1979.

Gachet, M. S. and Kunert, O. and Kaiser, M. and Brun, R. and Zehl, M. and Keller, W. and Munoz, R. A. and Bauer, R. and Schuehly, W.. (2011) Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. Journal of Natural Products, 74 (4). pp. 559-566.

Hata, Y. and Zimmermann, S. and Quitschau, M. and Kaiser, M. and Brun, R. and Hamburger, M. and Adams, M.. (2011) Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids. Journal of agricultural and food chemistry, Vol. 59, H. 17. pp. 9172-9176.

Vonthron-Sénécheau, C. and Kaiser, M. and Devambez, I. and Vastel, A. and Mussio, I. and Rusig, A. M.. (2011) Antiprotozoal activities of organic extracts from French marine seaweeds. Marine drugs , 9 (6). pp. 922-933.

Dua, V. K. and Verma, G. and Agarwal, D. D. and Kaiser, M. and Brun, R.. (2011) Antiprotozoal activities of traditional medicinal plants from the Garhwal region of North West Himalaya, India. Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs, Vol. 136, H. 1. pp. 123-128.

Kirmizibekmez, H. and Atay, I. and Kaiser, M. and Brun, R. and Cartagena, M. M. and Carballeira, N. M. and Yesilada, E. and Tasdemir, D.. (2011) Antiprotozoal activity of Melampyrum arvense and its metabolites. Phytotherapy research : an international journal devoted to pharmacological and toxocological evaluation of natural product derivatives, Vol. 25, H. 1. pp. 142-146.

Kaya, G. I. and Sarikaya, B. and Onur, M. A. and Somer, N. U. and Viladomat, F. and Codina, C. and Bastida, J. and Lauinger, I. L. and Kaiser, M. and Tasdemir, D.. (2011) Antiprotozoal alkaloids from Galanthus trojanus. Phytochemistry letters, Vol. 4, H. 3. pp. 301-305.

Broniatowska, B. and Allmendinger, A. and Kaiser, M. and Montamat-Sicotte D., and Hingley-Wilson S., and Lalvani, A. and Guiry, M. and Blunden, G. and Tasdemir, D.. (2011) Antiprotozoal, antitubercular and cytotoxic potential of cyanobacterial (blue-green algal) extracts from Ireland. Natural product communications, Vol. 6, H. 5. pp. 689-694.

Baragana, B. and McCarthy, O. and Sanchez, P. and Bosch-Navarrete C., and Kaiser, M. and Brun, R. and Whittingham, J. L. and Roberts, S. M. and Zhou, X. X. and Wilson, K. S. and Johansson, N. G. and Gonzalez-Pacanowska D., and Gilbert, I. H.. (2011) Beta-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 19 (7). pp. 2378-2391.

Mayence, A. and Vanden Eynde J. J., and Kaiser, M. and Brun, R. and Yarlett, N. and Huang, T. L.. (2011) Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 19 (24). pp. 7493-7500.

Schmidt, T. J. and Kaiser, M. and Brun, R.. (2011) Complete structural assignment of serratol, a cembrane-type diterpene from Boswellia serrata and evaluation of its antiprotozoal activity. Planta medica, 77 (8). pp. 849-850.

Kuhn-Nentwig, L. and Willems, J. and Seebeck, T. and Shalaby, T. and Kaiser, M. and Nentwig, W.. (2011) Cupiennin 1a exhibits a remarkably broad, non-stereospecific cytolytic activity on bacteria, protozoan parasites, insects, and human cancer cells. Amino Acids, 40 (1). pp. 69-76.

Regalado, E. L. and Turk, T. and Tasdemir, D. and Gorjanc, M. and Kaiser, M. and Thomas, O. P. and Fernandez, R. and Amade, P.. (2011) Cytotoxic and haemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium. Steroids : an international journal, Vol. 76, H. 12. pp. 1389-1396.

Hampton, S. E. and Baragana, B. and Schipani, A. and Bosch-Navarrete C., and Musso-Buendia J. A., and Recio, E. and Kaiser, M. and Whittingham, J. L. and Roberts, S. M. and Shevtsov, M. and Brannigan, J. A. and Kahnberg, P. and Brun, R. and Wilson, K. S. and Gonzalez-Pacanowska D., and Johansson, N. G. and Gilbert, I. H.. (2011) Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. ChemMedChem : chemistry enabling drug discovery, Vol. 6, H. 10. pp. 1816-1831.

Finlayson, R. and Pearce, A. N. and Page, M. J. and Kaiser, M. and Bourguet-Kondracki, M. L. and Harper, J. L. and Webb, V. L. and Copp, B. R.. (2011) Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. Journal of Natural Products, 74 (4). pp. 888-892.

Harel, D. and Khalid, S. A. and Kaiser, M. and Brun, R. and Wunsch, B. and Schmidt, T. J.. (2011) Encecalol angelate, an unstable chromene from Ageratum conyzoides L. : total synthesis and investigation of its antiprotozoal activity. Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs, Vol. 137, H. 1. pp. 620-650.

Hobbie, S. N. and Kaiser, M. and Schmidt, S. and Shcherbakov, D. and Janusic, T. and Brun, R. and Böttger, E. C.. (2011) Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma. PLoS neglected tropical diseases, Vol. 5, H. 5 , e1161.

Eberle, C. and Lauber, B. S. and Fankhauser, D. and Kaiser, M. and Brun, R. and Krauth-Siegel R. L., and Diederich, F.. (2011) Improved inhibitors of trypanothione reductase by combination of motifs : synthesis, inhibitory potency, binding mode, and antiprotozoal activities. ChemMedChem : chemistry enabling drug discovery, Vol. 6, H. 2. pp. 292-301.

Attioua, B. and Lagnika, L. and Yeo, D. and Antheaume, C. and Kaiser, M. and Weniger, B. and Lobstein, A. and Vonthron-Sénécheau C., . (2011) In vitro antiplasmodial and antileishmanial activities of flavonoids form Anogeissus leiocarpus (Combretaceae). International journal of pharmaceutical sciences review and research, Vol. 11, H. 2 , 001.

Kirmizibekmez, H. and Atay, I. and Kaiser, M. and Yesilada, E. and Tasdemir, D.. (2011) In vitro antiprotozoal activity of extracts of five Turkish Lamiaceae species. Natural Product Communications , 6 (11). pp. 1697-1700.

Pyana, P. P. and Ngay Lukusa, I. and Mumba Ngoyi, D. and Van Reet, N. and Kaiser, M. and Karhemere Bin Shamamba, S. and Buscher, P.. (2011) Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice. PLoS Neglected Tropical Diseases, 5 (4). e1025.

Ruda, G. F. and Nguyen, C. and Ziemkowski, P. and Felczak, K. and Kasinathan, G. and Musso-Buendia A., and Sund, C. and Zhou, X. X. and Kaiser, M. and Ruiz-Perez L. M., and Brun, R. and Kulikowski, T. and Johansson, N. G. and Gonzalez-Pacanowska D., and Gilbert, I. H.. (2011) Modified 5'-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase. ChemMedChem : chemistry enabling drug discovery, Vol. 6, H. 2. pp. 309-320.

Papadopoulou, M. V. and Bourdin, B. and Bloomer, W. D. and McKenzie, C. and Wilkinson, S. R. and Prasittichai, C. and Brun, R. and Kaiser, M. and Torreele, E.. (2011) Novel 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines as anti-chagasic agents. Journal of medicinal chemistry, 54 (23). pp. 8214-8223.

Jacobs, R. T. and Naré, B. and Wring, S. A. and Orr, M. D. and Chen, D. and Sligar, J. M. and Jenks, M. X. and Noe, R. A. and Bowling, T. S. and Mercer, L. T. and Rewerts, C. and Gaukel, E. and Owens, J. and Parham, R. and Randolph, R. and Beaudet, B. and Bacchi, C. J. and Yarlett, N. and Plattner, J. J. and Freund, Y. and Ding, C. and Akama, T. and Zhang, Y. K. and Brun, R. and Kaiser, M. and Scandale, I. and Don, R.. (2011) SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 Human African trypanosomiasis. PLoS neglected tropical diseases, Vol. 5, H. 6 , e1151.

Nieto, L. and Mascaraque, A. and Miller, F. and Glacial, F. and Rios Martinez C., and Kaiser, M. and Brun, R. and Dardonville, C.. (2011) Synthesis and antiprotozoal activity of N-alkoxy analogues of the trypanocidal lead compound 4,4'-bis(imidazolinylamino)diphenylamine with improved human blood-brain barrier permeability. Journal of medicinal chemistry, 54 (2). pp. 485-494.

Shi, X. L. and Ge, J. F. and Liu, B. Q. and Kaiser, M. and Wittlin, S. and Brun, R. and Ihara, M.. (2011) Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 21, H. 19. pp. 5804-5807.

Lu, Y. T. and Arai, C. and Ge, J. F. and Ren, W. S. and Kaiser, M. and Wittlin, S. and Brun, R. and Lu, J. M. and Ihara, M.. (2011) Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive phenothiazinium chlorides. Dyes and pigments : an international journal, Vol. 89, H. 1. pp. 44-48.

2010

Faist, J. and Seebacher, W. and Kaiser, M. and Brun, R. and Saf, R. and Weis, R.. (2010) Alkyl and dialkylaminoethyl derivatives of 5-amino-2-azabicyclo[3.2.2]nonanes and their antiplasmodial and antitrypanosomal activities. European Journal of Medicinal Chemistry, 45 (1). pp. 179-185.

Bonazzi, S. and Barbaras, D. and Patiny, L. and Scopelliti, R. and Schneider, P. and Cole, S. T. and Kaiser, M. and Brun, R. and Gademann, K.. (2010) Antimalarial and antitubercular nostocarboline and eudistomin derivatives: Synthesis, in vitro and in vivo biological evaluation. Bioorganic and Medicinal Chemistry, 18 (4). pp. 1464-1476.

Spavieri, J. and Allmendinger, A. and Kaiser, M. and Casey, R. and Hingley-Wilson S., and Lalvani, A. and Guiry, M. D. and Blunden, G. and Tasdemir, D.. (2010) Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters. Phytotherapy research : an international journal devoted to pharmacological and toxocological evaluation of natural product derivatives, Vol. 24, H. 11. pp. 1724-1729.

Regalado, E. L. and Tasdemir, D. and Kaiser, M. and Cachet, N. and Amade, P. and Thomas, O. P.. (2010) Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium. Journal of natural products, Vol. 73, H. 8. pp. 1404-1410.

Spavieri, J. and Kaiser, M. and Casey, R. and Hingley-Wilson S., and Lalvani, A. and Blunden, G. and Tasdemir, D.. (2010) Antiprotozoal, antimycobacterial and cytotoxic potential of some british green algae. Phytotherapy research : an international journal devoted to pharmacological and toxocological evaluation of natural product derivatives, Vol. 24, H. 7. pp. 1095-1098.

Allmendinger, A. and Spavieri, J. and Kaiser, M. and Casey, R. and Hingley-Wilson S., and Lalvani, A. and Guiry, M. and Blunden, G. and Tasdemir, D.. (2010) Antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three British and Irish red algae. Phytotherapy research : an international journal devoted to pharmacological and toxocological evaluation of natural product derivatives, Vol. 24, H. 7. pp. 1099-1103.

Fotie, J. and Kaiser, M. and Delfin, D. A. and Manley, J. and Reid, C. S. and Paris, J. M. and Wenzler, T. and Maes, L. and Mahasenan, K. V. and Li, C. and Werbovetz, K. A.. (2010) Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives. Journal of medicinal chemistry, 53 (3). pp. 966-982.

Gachet, M. S. and Lecaro, J. S. and Kaiser, M. and Brun, R. and Navarrete, H. and Munoz, R. A. and Bauer, R. and Schuhly, W.. (2010) Assessment of anti-protozoal activity of plants traditionally used in Ecuador in the treatment of leishmaniasis. Journal of ethnopharmacology : an interdisciplinary journal devoted to bioscientific research on indigenous drugs, Vol. 128, H. 1. pp. 184-197.

Scala, F. and Fattorusso, E. and Menna, M. and Taglialatela-Scafati O., and Tierney, M. and Kaiser, M. and Tasdemir, D.. (2010) Bromopyrrole alkaloids as lead compounds against protozoan parasites. Marine drugs, Vol. 8, H. 7. pp. 2162-2174.

Gigante, F. and Kaiser, M. and Brun, R. and Gilbert, I. H.. (2010) Design and preparation of sterol mimetics as potential antiparasitics. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 18 (20). pp. 7291-7301.

Faist, J. and Seebacher, W. and Kaiser, M. and Brun, R. and Saf, R. and Weis, R.. (2010) Dialkylaminoalkyl derivatives of bicyclic compounds with antiplasmodial activity. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 18 (18). pp. 6796-6804.

Ge, J. F. and Arai, C. and Yang, M. and Bakar, M. A. and Lu, J. and Ismail, N. S. M. and Wittlin, S. and Kaiser, M. and Brun, R. and Charman, S. A. and Nguyen, T. and Morizzi, J. and Itoh, I. and Ihara, M.. (2010) Discovery of novel benzo[a]phenoxazine SSJ-183 as a drug candidate for malaria. ACS medicinal chemistry letters, Vol. 1, H. 7. pp. 360-364.

Nare, B. and Wring, S. and Bacchi, C. and Beaudet, B. and Bowling, T. and Brun, R. and Chen, D. and Ding, C. and Freund, Y. and Gaukel, E. and Hussain, A. and Jarnagin, K. and Jenks, M. and Kaiser, M. and Mercer, L. and Mejia, E. and Noe, A. and Orr, M. and Parham, R. and Plattner, J. and Randolph, R. and Rattendi, D. and Rewerts, C. and Sligar, J. and Yarlett, N. and Don, R. and Jacobs, R.. (2010) Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late stage central nervous system African Trypanosomiasis. Antimicrobial agents and chemotherapy : AAC, Vol. 54, H. 10. pp. 4379-4388.

Torreele, E. and BourdinTrunz, B. and Tweats, D. and Kaiser, M. and Brun, R. and Mazue, G. and Bray, M. A. and Pecoul, B.. (2010) Fexinidazole: a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. PLoS neglected tropical diseases, Vol. 4, H. 12 , e923.

Yang, M. and Arai, C. and Bakar, M. A. and Lu, J. and Ge, J. F. and Pudhom, K. and Takasu, K. and Kasai, K. and Kaiser, M. and Brun, R. and Yardley, V. and Itoh, I. and Ihara, M.. (2010) Fluorinated rhodacyanine (SJL-01) possessing high efficacy for visceral leishmaniasis (VL). Journal of medicinal chemistry, 53 (1). pp. 368-373.

Zohrabi-Kalantari, V. and Heidler, P. and Kaiser, M. and Brun, R. and Kamper, C. and Link, A.. (2010) Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N(6)-substituted 5 (`)-amino-5 (`)-deoxyadenosines. Molecular Diversity, 14 (2). pp. 307-320.

Zohrabi-Kalantari, V. and Heidler, P. and Kaiser, M. and Brun, R. and Kamper, C. and Link, A.. (2010) Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N6-substituted 5'-amino-5'-deoxyadenosines. Molecular Diversity, 14 (2). pp. 307-320.

Gachet, M. S. and Kunert, O. and Kaiser, M. and Brun, R. and Munoz, R. A. and Bauer, R. and Schuhly, W.. (2010) Jacaranone-derived glucosidic esters from Jacaranda glabra and their activity against Plasmodium falciparum. Journal of Natural Products, Vol. 73, H. 4. pp. 553-556.

Pacorel, B. and Leung, S. C. and Stachulski, A. V. and Davies, J. and Vivas, L. and Lander, H. and Ward, S. A. and Kaiser, M. and Brun, R. and O'Neill P. M., . (2010) Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin. Journal of medicinal chemistry, 53 (2). pp. 633-640.

Mallari, J. P. and Zhu, F. and Lemoff, A. and Kaiser, M. and Lu, M. and Brun, R. and Guy, R. K.. (2010) Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 18 (23). pp. 8302-8309.

Bringmann, G. and Bischof, S. K. and Müller, S. and Gulder, T. and Winter, C. and Stich, A. and Moll, H. and Kaiser, M. and Brun, R. and Dreher, J. and Baumann, K.. (2010) QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 45 (11). pp. 5370-5383.

Nour, A. M. and Khalid, S. A. and Kaiser, M. and Brun, R. and Abdalla, W. E. and Schmidt, T. J.. (2010) The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. Journal of Ethnopharmacology, Vol. 129, H. 1. pp. 127-130.

2009

Kuettel, S. and Mosimann, M. and Mäser, P. and Kaiser, M. and Brun, R. and Scapozza, L. and Perozzo, R.. (2009) Adenosine kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics. PLoS Neglected Tropical Diseases, Vol. 3, H. 8 , e506.

Adams, M. and Plitzko, I. and Kaiser, M. and Brun, R. and Hamburger, M.. (2009) Anti-plasmodial flavonoid from Pistacia atlantica. Phytochemistry Letters, Vol. 2. pp. 159-162.

Schlapper, C. and Seebacher, W. and Faist, J. and Kaiser, M. and Brun, R. and Saf, R. and Weis, R.. (2009) Antiplasmodial and antitrypanosomal activities of aminobicyclo[2.2.2]octyl omega-aminoalkanoates. European journal of medicinal chemistry, 44 (2). pp. 736-744.

Faist, J. and Seebacher, W. and Schlapper, C. and Kaiser, M. and Brun, R. and Saf, R. and Weis, R.. (2009) Antiplasmodial and antitrypanosomal activity of bicyclic amides and esters of dialkylamino acids. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 17 (10). pp. 3595-3603.

Dardonville, C. and Fernandez-Fernandez C., and Gibbons, S. L. and Jagerovic, N. and Nieto, L. and Ryan, G. and Kaiser, M. and Brun, R.. (2009) Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 9. pp. 3815-3821.

Faist, J. and Seebacher, W. and Kaiser, M. and Brun, R. and Saf, R. and Weis, R.. (2009) Bicyclic amido compounds with antiprotozoal activity. Monatshefte für Chemie = Chemical monthly : an international journal of chemistry, Vol. 140, H. 10. pp. 1261-1268.

Musonda, C. C. and Whitlock, G. A. and Witty, M. J. and Brun, R. and Kaiser, M.. (2009) Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 19, H. 2. pp. 481-484.

McCarthy, O. and Musso-Buendia A., and Kaiser, M. and Brun, R. and Ruiz-Perez L. M., and Johansson, N. G. and Pacanowska, D. G. and Gilbert, I. H.. (2009) Design, synthesis and evaluation of novel uracil acetamide derivatives as potential inhibitors of Plasmodium falciparum dUTP nucleotidohydrolase. European journal of medicinal chemistry, 44 (2). pp. 678-688.

Adams, M. and Plitzko, I. and Kaiser, M. and Brun, R. and Hamburger, M.. (2009) HPLC-profiling for antiplasmodial compounds-3-methoxycarpachromene from Pistacia atlantica. Planta medica : Zeitschrift für Arzneipflanzenforschung : official organ of the Society for Medicinal Plant Research, Vol. 75, H. 9. p. 948.

Heidler, P. and Zohrabi-Kalantari V., and Kaiser, M. and Brun, R. and Emmrich, T. and Link, A.. (2009) Inhibitors of adenosine consuming parasites through polymer-assisted solution phase synthesis of lipophilic 5'-amido-5'-deoxyadenosine derivatives. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 17, H. 4. pp. 1428-1436.

Gachet, M. S. and Schuhly, W. and Kunert, O. and Kaiser, M. and Brun, R. and Munoz, R. A. and Bauer, R.. (2009) Jacaranone derived glucosidic esters from Jacaranda glabra. Planta medica : Zeitschrift für Arzneipflanzenforschung : official organ of the Society for Medicinal Plant Research, Vol. 75, H. 9. pp. 901-902.

Riente, R. R. and Souza, V. P. and Carvalho, S. A. and Kaiser, M. and Brun, R. and da Silva E. F., . (2009) Leishmanicidal activity of new megazol derivatives. Medicinal chemistry, Vol. 5, H. 4. pp. 392-397.

Portmann, C. and Blom, J. F. and Kaiser, M. and Brun, R. and Juttner, F. and Gademann, K.. (2009) New antiplasmodial natural products from cyanobacteria: linking their ecological role to their therapeutic potential. Planta medica : Zeitschrift für Arzneipflanzenforschung : official organ of the Society for Medicinal Plant Research, Vol. 75, H. 9. p. 886.

Barker, R. H. and Liu, H. and Hirth, B. and Celatka, C. A. and Fitzpatrick, R. and Xiang, Y. and Willert, E. K. and Phillips, M. A. and Kaiser, M. and Bacchi, C. J. and Rodriguez, A. and Yarlett, N. and Klinger, J. D. and Sybertz, E.. (2009) Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 5. pp. 2052-2058.

Baliani, A. and Peal, V. and Gros, L. and Brun, R. and Kaiser, M. and Barrett, M. P. and Gilbert, I. H.. (2009) Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites. Organic & biomolecular chemistry : an international journal of synthetic, physical and biomolecular organic chemistry, Vol. 7, H. 6. pp. 1154-1166.

Stump, B. and Eberle, C. and Schweizer, W. B. and Kaiser, M. and Brun, R. and Krauth-Siegel R. L., and Lentz, D. and Diederich, F.. (2009) Pentafluorosulfanyl as a novel building block for enzyme inhibitors: trypanothione reductase inhibition and antiprotozoal activities of diarylamines. ChemBioChem : a European journal of chemical biology, Vol. 10, H. 1. pp. 79-83.

Schmidt, T. J. and Nour, A. M. and Khalid, S. A. and Kaiser, M. and Brun, R.. (2009) Quantitative structure--antiprotozoal activity relationships of sesquiterpene lactones. Molecules : a journal of synthetic chemistry and natural product chemistry, Vol. 14, H. 6. pp. 2062-2076.

Gigante, F. and Kaiser, M. and Brun, R. and Gilbert, I. H.. (2009) SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agents. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 17, H. 16. pp. 5950-5961.

Berger, H. and Seebacher, W. and Kaiser, M. and Brun, R. and Saf, R. and Weis, R.. (2009) SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols. Monatshefte für Chemie = Chemical monthly : an international journal of chemistry, Vol. 140, H. 5. pp. 495-502.

Van Baelen G., and Hostyn, S. and Dhooghe, L. and Tapolcsanyi, P. and Matyus, P. and Lemiere, G. and Dommisse, R. and Kaiser, M. and Brun, R. and Cos, P. and Maes, L. and Hajos, G. and Riedl, Z. and Nagy, I. and Maes, B. U. and Pieters, L.. (2009) Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 17, H. 20. pp. 7209-7217.

Pudhom, K. and Ge, M. F. and Arai, C. and Yang, M. and Kaiser, M. and Wittlin, S. and Brun, R. and Itoh, I. and Ihara, M.. (2009) Synthesis and biological properties of a rhodacyanine derivative, Ssj-127, having high efficacy against malaria protozoa. Heterocycles : an international journal for reviews and communications in heterocyclic chemistry, Vol. 77, H. 1. pp. 207-210.

Musonda, C. C. and Whitlock, G. A. and Witty, M. J. and Brun, R. and Kaiser, M.. (2009) Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 19, H. 2. pp. 401-405.

Link, A. and Heidler, P. and Kaiser, M. and Brun, R.. (2009) Synthesis of a series of N(6)-substituted adenosines with activity against trypanosomatid parasites. European Journal of Medicinal Chemistry, 44 (9). pp. 3665-3671.

Wolkinger, V. and Weis, R. and Belaj, F. and Kaiser, M. and Brun, R. and Saf, R. and Seebacher, W.. (2009) Synthesis of novel diazabicycles and their antiprotozoal activities. Australian journal of chemistry, Vol. 62, H. 9. pp. 1166-1172.

Eberle, C. and Burkhard, J. A. and Stump, B. and Kaiser, M. and Brun, R. and Krauth-Siegel R. L., and Diederich, F.. (2009) Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on mepacrine-conjugated diaryl sulfide scaffolds. ChemMedChem : chemistry enabling drug discovery, Vol. 4, H. 12. pp. 2034-2044.

Nour, A. M. and Khalid, S. A. and Kaiser, M. and Brun, R. and Abdallah, W. E. and Schmidt, T. J.. (2009) The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from Xanthium brasilicum. Planta medica : Zeitschrift für Arzneipflanzenforschung : official organ of the Society for Medicinal Plant Research, Vol. 75, H. 2. pp. 1363-1368.

Karioti, A. and Skaltsa, H. and Kaiser, M. and Tasdemir, D.. (2009) Trypanocidal, leishmanicidal and cytotoxic effects of anthecotulide-type linear sesquiterpene lactones from Anthemis auriculata. Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 16, H. 8. pp. 783-787.

Holloway, G. A. and Charman, W. N. and Fairlamb, A. H. and Brun, R. and Kaiser, M. and Kostewicz, E. and Novello, P. M. and Parisot, J. P. and Richardson, J. and Street, I. P. and Watson, K. G. and Baell, J. B.. (2009) Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with anti-parasitic activity. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 7. pp. 2824-2833.

2008

Portmann, C. and Blom, J. F. and Kaiser, M. and Brun, R. and Juttner, F. and Gademann, K.. (2008) Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from Microcystis aeruginosa PCC 7806 and their antiparasite evaluation. Journal of natural products, Vol. 71, H. 11. pp. 1891-1896.

1998

Ming, X. F. and Kaiser, M. and Moroni, C.. (1998) c-jun N-terminal kinase is involved in AUUUA-mediated interleukin-3 mRNA turnover in mast cells. The EMBO journal, Vol. 17, H. 20. pp. 6039-6048.

This list was generated on Fri Mar 29 11:57:50 2024 CET.