Items where Author is "Harms, Alexander"

Article

Shaidullina, Aisylu and Harms, Alexander. (2022) Antiviral death punch by ADP-ribosylating bacterial toxins. Trends in Microbiology, 30 (10). pp. 920-921.

Maffei, Enea and Burkolter, Marco and Heyer, Yannik and Egli, Adrian and Jenal, Urs and Harms, Alexander. (2022) Phage Paride hijacks bacterial stress responses to kill dormant, antibiotic-tolerant cells. bioRxiv. p. 477855.

Shaidullina, Aisylu and Harms, Alexander. (2022) Toothpicks, logic, and next-generation sequencing: systematic investigation of bacteriophage-host interactions. Current Opinion in Microbiology, 70. p. 102225.

Schirmer, Tilman and de Beer, Tjaart A. P. and Tamegger, Stefanie and Harms, Alexander and Dietz, Nikolaus and Dranow, David M. and Edwards, Thomas E. and Myler, Peter J. and Phan, Isabelle and Dehio, Christoph. (2021) Evolutionary Diversification of Host-Targeted; Bartonella; Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9 (8). p. 23.

Maffei, Enea and Harms, Alexander. (2021) Messages from the dead protect bacteria from viral attack. The EMBO Journal, 41 (3). e110382.

Dietz, Nikolaus and Huber, Markus and Sorg, Isabel and Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2021) Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1). Proceedings of the National Academy of Sciences, 118 (12). e2023245118.

Maffei, Enea and Shaidullina, Aisylu and Burkolter, Marco and Heyer, Yannik and Estermann, Fabienne and Druelle, Valentin and Sauer, Patrick and Willi, Luc and Michaelis, Sarah and Hilbi, Hubert and Thaler, David Solomon and Harms, Alexander. (2021) Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection. PLoS Biology, 19 (11). e300142.

Sorg, Isabel and Schmutz, Christoph and Lu, Yun-Yueh and Fromm, Katja and Siewert, Lena K. and Bögli, Alexandra and Strack, Kathrin and Harms, Alexander and Dehio, Christoph. (2020) A Bartonella effector acts as signaling hub for intrinsic STAT3 activation to trigger anti-inflammatory responses. Cell host & microbe, 27 (3). pp. 476-485.

Fino, Cinzia and Vestergaard, Martin and Ingmer, Hanne and Pierrel, Fabien and Gerdes, Kenn and Harms, Alexander. (2020) PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10. MicrobiologyOpen, 9 (8). e1064.

Horesh, Gal and Fino, Cinzia and Harms, Alexander and Dorman, Matthew J. and Parts, Leopold and Gerdes, Kenn and Heinz, Eva and Thomson, Nicholas R.. (2020) Type II and type IV toxin-antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population. Nucleic Acids Research, 48 (8). pp. 4357-4370.

Svenningsen, Mikkel Skjoldan and Veress, Alexandra and Harms, Alexander and Mitarai, Namiko and Semsey, Szabolcs. (2019) Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells. Scientific Reports, 9 (1). p. 6056.

Harms, Alexander and Diard, Médéric. (2019) Crowd Controlled-Host Quorum Sensing Drives Phage Decision. Cell host & microbe, 25 (2). pp. 179-181.

Balaban, Nathalie Q. and Helaine, Sophie and Lewis, Kim and Ackermann, Martin and Aldridge, Bree and Andersson, Dan I. and Brynildsen, Mark P. and Bumann, Dirk and Camilli, Andrew and Collins, James J. and Dehio, Christoph and Fortune, Sarah M. and Ghigo, Jean-Marc and Hardt, Wolf-Dietrich and Harms, Alexander and Heinemann, Matthias and Hung, Deborah T. and Jenal, Urs and Levin, Bruce R. and Michiels, Jan and Storz, Gisela and Tan, Man-Wah and Tenson, Tanel and Van Melderen, Laurence and Zinkernagel, Annelies. (2019) Definitions and guidelines for research on antibiotic persistence. Nature Reviews Microbiology, 17 (7). pp. 441-448.

Harms, Alexander and Liesch, Marius and Körner, Jonas and Québatte, Maxime and Engel, Philipp and Dehio, Christoph. (2017) A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella. PLoS Genetics, 13 (10). e1007077.

Harms, Alexander and Segers, Francisca H. I. D. and Quebatte, Maxime and Mistl, Claudia and Manfredi, Pablo and Körner, Jonas and Chomel, Bruno B. and Kosoy, Michael and Maruyama, Soichi and Engel, Philipp and Dehio, Christoph. (2017) Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella. Genome biology and evolution, 9 (3). pp. 761-776.

Québatte, Maxime and Christen, Matthias and Harms, Alexander and Körner, Jonas and Christen, Beat and Dehio, Christoph. (2017) Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen. Cell Systems, 4 (6). pp. 611-621.e6.

Harms, Alexander and Fino, Cinzia and Sørensen, Michael A. and Semsey, Szabolcs and Gerdes, Kenn. (2017) Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells. MBio, 8 (6). ii:e01964-17.

Harms, Alexander and Stanger, Frédéric Valentin and Dehio, Christoph. (2016) Biological Diversity and Molecular Plasticity of FIC Domain Proteins. Annual Reviews of Microbiology, 70. pp. 341-360.

Stanger, Frédéric V. and Harms, Alexander and Dehio, Christoph and Schirmer, Tilman. (2016) Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS ONE, 11 (9). e0163654.

Stanger, Frédéric V. and Burmann, Björn M. and Harms, Alexander and Aragão, Hugo and Mazur, Adam and Sharpe, Timothy and Dehio, Christoph and Hiller, Sebastian and Schirmer, Tilman. (2016) Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proceedings of the National Academy of Sciences of the United States of America, 113 (5). E529-E537.

Harms, Alexander and Stanger, Frédéric Valentin and Scheu, Patrick Daniel and de Jong, Imke Greet and Goepfert, Arnaud and Glatter, Timo and Gerdes, Kenn and Schirmer, Tilman and Dehio, Christoph. (2015) Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology. Cell Reports, 12 (9). pp. 1497-1507.

Pieles, Kathrin and Glatter, Timo and Harms, Alexander and Schmidt, Alexander and Dehio, Christoph. (2014) An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9). pp. 1048-1052.

Engel, Philipp and Goepfert, Arnaud and Stanger, Frédéric V. and Harms, Alexander and Schmidt, Alexander and Schirmer, Tilman and Dehio, Christoph. (2012) Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482 (7383). pp. 107-110.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the Radar : Molecular Pathogenesis of Bartonella spp. Clinical microbiology reviews, Vol. 25, H. 1. pp. 42-78.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the radar: molecular pathogenesis of Bartonella spp. Clinical microbiology reviews, 25 (1). pp. 42-78.

Book Section

Maffei, Enea and Fino, Cinzia and Harms, Alexander. (2021) Antibiotic Tolerance and Persistence Studied Throughout Bacterial Growth Phases. In: Bacterial Persistence, 2357. Cham, pp. 23-40.

Harms, Alexander. (2019) The Biology of Persister Cells in Escherichia coli. In: Persister Cells and Infectious Disease. Cham, pp. 39-57.

Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2013) Type II Toxin-Antitoxin Loci: The fic Family. In: Prokaryotic Toxin-Antitoxins. Heidelberg, pp. 177-187.

Thesis

Harms, Alexander. FIC domain toxins are the origin of intra- and inter-kingdom effectors of Bartonella. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Preprint

Maffei, Enea and Shaidullina, Aisylu and Burkolter, Marco and Druelle, Valentin and Willi, Luc and Estermann, Fabienne and Michaelis, Sarah and Hilbi, Hubert and Thaler, David S. and Harms, Alexander. (2021) Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection.

Working Paper

Sellner, Benjamin and Prakapaitė, Rūta and van Berkum, Margo and Heinemann, Matthias and Harms, Alexander and Jenal, Urs. (2021) A new sugar for an old phage: A c-di-GMP dependent polysaccharide pathway sensitizes E. coli for bacteriophage infection.

Dietz, Nikolaus Balthasar and Huber, Markus and Sorg, Isabel and Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2020) Structural basis for selective targeting of Rac subfamily GTPases by a bacterial effector protein.

Other

Reinders, Alberto and Sellner, Benjamin and Fadel, Firas and van Berkum, Margo and Kaczmarczyk, Andreas and Ozaki, Shogo and Rueher, Johanna and Manfredi, Pablo and Sangermani, Matteo and Harms, Alexander and Perez, Camilo and Schirmer, Tilman and Jenal, Urs. (2021) Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity.