Items where contributor is "Schier, Alexander F"

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Shafer, Maxwell E. R. and Sawh, Ahilya N. and Schier, Alexander F.. (2021) Gene family evolution underlies cell type diversification in the hypothalamus of teleosts.


Lin, Qian and Manley, Jason and Helmreich, Magdalena and Schlumm, Friederike and Li, Jennifer M. and Robson, Drew N. and Engert, Florian and Schier, Alexander and Nöbauer, Tobias and Vaziri, Alipasha. (2020) Cerebellar Neurodynamics Predict Decision Timing and Outcome on the Single-Trial Level. Cell, 180 (3). pp. 536-551.e17.


Dubrulle, Julien and Jordan, Benjamin M. and Akhmetova, Laila and Farrell, Jeffrey A. and Kim, Seok-Hyung and Solnica-Krezel, Lilianna and Schier, Alexander F.. (2015) Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. eLife, 4. e05042.


Rabani, Michal and Raychowdhury, Raktima and Jovanovic, Marko and Rooney, Michael and Stumpo, Deborah J. and Pauli, Andrea and Hacohen, Nir and Schier, Alexander F. and Blackshear, Perry J. and Friedman, Nir and Amit, Ido and Regev, Aviv. (2014) High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell, 159 (7). pp. 1698-1710.

Schier, Alexander F.. (2014) Obituary: Walter J. Gehring (1939-2014). Development, 141 (17). pp. 3289-3291.

Richter, Constance and Woods, Ian G. and Schier, Alexander F.. (2014) Neuropeptidergic control of sleep and wakefulness. Annual Review of Neuroscience, 37. pp. 503-531.

Gagnon, James A. and Valen, Eivind and Thyme, Summer B. and Huang, Peng and Akhmetova, Laila and Pauli, Andrea and Montague, Tessa G. and Zimmerman, Steven and Richter, Constance and Schier, Alexander F.. (2014) Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PLoS ONE, 9 (5). e98186.

Woods, Ian G. and Schoppik, David and Shi, Veronica J. and Zimmerman, Steven and Coleman, Haley A. and Greenwood, Joel and Soucy, Edward R. and Schier, Alexander F.. (2014) Neuropeptidergic signaling partitions arousal behaviors in zebrafish. Journal of Neuroscience, 34 (9). pp. 3142-3160.

Pauli, Andrea and Norris, Megan L. and Valen, Eivind and Chew, Guo-Liang and Gagnon, James A. and Zimmerman, Steven and Mitchell, Andrew and Ma, Jiao and Dubrulle, Julien and Reyon, Deepak and Tsai, Shengdar Q. and Joung, J. Keith and Saghatelian, Alan and Schier, Alexander F.. (2014) Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science, 343 (6172). p. 1248636.

Zhang, Yong and Vastenhouw, Nadine L. and Feng, Jianxing and Fu, Kai and Wang, Chenfei and Ge, Ying and Pauli, Andrea and van Hummelen, Paul and Schier, Alexander F. and Liu, X. Shirley. (2014) Canonical nucleosome organization at promoters forms during genome activation. Genome Research, 24 (2). pp. 260-266.


Schier, Alexander F.. (2013) Should I stay or should I go: neuromodulators of behavioral states. Cell, 154 (5). pp. 955-956.

Pan, Y. Albert and Freundlich, Tom and Weissman, Tamily A. and Schoppik, David and Wang, X. Cindy and Zimmerman, Steve and Ciruna, Brian and Sanes, Joshua R. and Lichtman, Jeff W. and Schier, Alexander F.. (2013) Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development, 140 (13). pp. 2835-2846.

Rihel, Jason and Schier, Alexander F.. (2013) Sites of action of sleep and wake drugs: insights from model organisms. Current Opinion in Neurobiology, 23 (5). pp. 831-840.


Vastenhouw, Nadine L. and Schier, Alexander F.. (2012) Bivalent histone modifications in early embryogenesis. Current Opinion in Cell Biology, 24 (3). pp. 374-386.

Müller, Patrick and Rogers, Katherine W. and Jordan, Ben M. and Lee, Joon S. and Robson, Drew and Ramanathan, Sharad and Schier, Alexander F.. (2012) Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science, 336 (6082). pp. 721-724.

Low, Sean E. and Woods, Ian G. and Lachance, Mathieu and Ryan, Joel and Schier, Alexander F. and Saint-Amant, Louis. (2012) Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of Neurophysiology, 108 (1). pp. 148-159.

Xu, Cong and Fan, Zi Peng and Müller, Patrick and Fogley, Rachel and DiBiase, Anthony and Trompouki, Eirini and Unternaehrer, Juli and Xiong, Fengzhu and Torregroza, Ingrid and Evans, Todd and Megason, Sean G. and Daley, George Q. and Schier, Alexander F. and Young, Richard A. and Zon, Leonard I.. (2012) Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell, 22 (3). pp. 625-638.


Caron, Sophie J. C. and Prober, David and Choy, Margaret and Schier, Alexander F.. (2008) In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development, 135 (19). pp. 3259-3269.

Douglass, Adam D. and Kraves, Sebastian and Deisseroth, Karl and Schier, Alexander F. and Engert, Florian. (2008) Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current Biology, 18 (15). pp. 1133-1137.

Woods, Ian G. and Schier, Alexander F.. (2008) Targeted mutagenesis in zebrafish. Nature Biotechnology, 26 (6). pp. 650-651.

Knaut, Holger and Schier, Alexander F.. (2008) Clearing the path for germ cells. Cell, 132 (3). pp. 337-339.


Bennett, James T. and Stickney, Heather L. and Choi, Wen-Yee and Ciruna, Brian and Talbot, William S. and Schier, Alexander F.. (2007) Maternal nodal and zebrafish embryogenesis. Nature, 450 (7167). E1-2; discussion E2-E4.

Choi, Wen-Yee and Giraldez, Antonio J. and Schier, Alexander F.. (2007) Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science, 318 (5848). pp. 271-274.

Schier, Alexander F.. (2007) The maternal-zygotic transition: death and birth of RNAs. Science, 316 (5823). pp. 406-407.

Bennett, James T. and Joubin, Katherine and Cheng, Simon and Aanstad, Pia and Herwig, Ralf and Clark, Matthew and Lehrach, Hans and Schier, Alexander F.. (2007) Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental Biology, 304 (2). pp. 525-540.

Karkera, J. D. and Lee, J. S. and Roessler, E. and Banerjee-Basu, S. and Ouspenskaia, M. V. and Mez, J. and Goldmuntz, E. and Bowers, P. and Towbin, J. and Belmont, J. W. and Baxevanis, A. D. and Schier, A. F. and Muenke, M.. (2007) Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. American Journal of Human Genetics, 81 (5). pp. 987-994.


Prober, David A. and Rihel, Jason and Onah, Anthony A. and Sung, Rou-Jia and Schier, Alexander F.. (2006) Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. Journal of Neuroscience, 26 (51). pp. 13400-13410.

Mishima, Yuichiro and Giraldez, Antonio J. and Takeda, Yasuaki and Fujiwara, Toshinobu and Sakamoto, Hiroshi and Schier, Alexander F. and Inoue, Kunio. (2006) Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Current Biology, 16 (21). pp. 2135-2142.

Obara, Tomoko and Mangos, Steven and Liu, Yan and Zhao, Jinhua and Wiessner, Stephanie and Kramer-Zucker, Albrecht G. and Olale, Felix and Schier, Alexander F. and Drummond, Iain A.. (2006) Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology, 17 (10). pp. 2706-2718.

Giraldez, Antonio J. and Mishima, Yuichiro and Rihel, Jason and Grocock, Russell J. and Van Dongen, Stijn and Inoue, Kunio and Enright, Anton J. and Schier, Alexander F.. (2006) Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science, 312 (5770). pp. 75-79.

Ciruna, Brian and Jenny, Andreas and Lee, Diana and Mlodzik, Marek and Schier, Alexander F.. (2006) Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature, 439 (7073). pp. 220-224.

Schier, A. F. and Giraldez, A. J.. (2006) MicroRNA function and mechanism: insights from zebra fish. Cold Spring Harbor Symposia on Quantitative Biology, 71. pp. 195-203.


Schier, Alexander F.. (2005) Axis formation: squint comes into focus. Current Biology, 15 (24). R1002-R1005.

Schier, Alexander F. and Talbot, William S.. (2005) Molecular genetics of axis formation in zebrafish. Annual Review of Genetics, 39. pp. 561-613.

Knaut, Holger and Blader, Patrick and Strähle, Uwe and Schier, Alexander F.. (2005) Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron, 47 (5). pp. 653-666.

Sagasti, Alvaro and Guido, Matthew R. and Raible, David W. and Schier, Alexander F.. (2005) Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current Biology, 15 (9). pp. 804-814.

Kramer-Zucker, Albrecht G. and Olale, Felix and Haycraft, Courtney J. and Yoder, Bradley K. and Schier, Alexander F. and Drummond, Iain A.. (2005) Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development, 132 (8). pp. 1907-1921.

Giraldez, Antonio J. and Cinalli, Ryan M. and Glasner, Margaret E. and Enright, Anton J. and Thomson, J. Michael and Baskerville, Scott and Hammond, Scott M. and Bartel, David P. and Schier, Alexander F.. (2005) MicroRNAs regulate brain morphogenesis in zebrafish. Science, 308 (5723). pp. 833-838.

Dutta, Sunit and Dietrich, Jens-Erik and Aspöck, Gudrun and Burdine, Rebecca D. and Schier, Alexander and Westerfield, Monte and Varga, Zoltán M.. (2005) pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development, 132 (7). pp. 1579-1590.

Le Good, J. Ann and Joubin, Katherine and Giraldez, Antonio J. and Ben-Haim, Nadav and Beck, Séverine and Chen, Yu and Schier, Alexander F. and Constam, Daniel B.. (2005) Nodal stability determines signaling range. Current Biology, 15 (1). pp. 31-36.

Tyurina, Oksana V. and Guner, Burcu and Popova, Evgenya and Feng, Jianchi and Schier, Alexander F. and Kohtz, Jhumku D. and Karlstrom, Rolf O.. (2005) Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental Biology, 277 (2). pp. 537-556.


Schier, Alexander. (2004) Alexander Schier. Current Biology, 14 (13). R494.

Cheng, Simon K. and Olale, Felix and Brivanlou, Ali H. and Schier, Alexander F.. (2004) Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. PLoS biology, 2 (2). E30.

Schier, Alexander F.. (2004) Developmental biology: tail of decay. Nature, 427 (6973). pp. 403-404.


Schier, Alexander F.. (2003) Nodal signaling in vertebrate development. Annual review of cell and developmental biology, 19. pp. 589-621.

Kunwar, Prabhat S. and Zimmerman, Steven and Bennett, James T. and Chen, Yu and Whitman, Malcolm and Schier, Alexander F.. (2003) Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development, 130 (23). pp. 5589-5599.

Dougan, Scott T. and Warga, Rachel M. and Kane, Donald A. and Schier, Alexander F. and Talbot, William S.. (2003) The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development, 130 (9). pp. 1837-1851.

Karlstrom, Rolf O. and Tyurina, Oksana V. and Kawakami, Atsushi and Nishioka, Noriyuki and Talbot, William S. and Sasaki, Hiroshi and Schier, Alexander F.. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development, 130 (8). pp. 1549-1564.

Schier, Alexander F.. (2003) Chemokine signaling: rules of attraction. Current Biology, 13 (5). R192-R194.

Cheng, Simon K. and Olale, Felix and Bennett, James T. and Brivanlou, Ali H. and Schier, Alexander F.. (2003) EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes and Development, 17 (1). pp. 31-36.


Chen, Yu and Schier, Alexander F.. (2002) Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. Current Biology, 12 (24). pp. 2124-2128.

Ciruna, Brian and Weidinger, Gilbert and Knaut, Holger and Thisse, Bernard and Thisse, Christine and Raz, Erez and Schier, Alexander F.. (2002) Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America, 99 (23). pp. 14919-14924.

Moon, Ho-Sang and Jacobson, Eric M. and Khersonsky, Sonya M. and Luzung, Michael R. and Walsh, Daniel P. and Xiong, Wennan and Lee, Jae Wook and Parikh, Puja B. and Lam, Jennifer C. and Kang, Tae-Wook and Rosania, Gustavo R. and Schier, Alexander F. and Chang, Young-Tae. (2002) A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society, 124 (39). pp. 11608-11609.

de la Cruz, June M. and Bamford, Richard N. and Burdine, Rebecca D. and Roessler, Erich and Barkovich, James A. and Donnai, Dian and Schier, Alexander F. and Muenke, Maximilian. (2002) A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human genetics, 110 (5). pp. 422-428.

Yamashita, Susumu and Miyagi, Chiemi and Carmany-Rampey, Amanda and Shimizu, Takashi and Fujii, Ritsuko and Schier, Alexander F. and Hirano, Toshio. (2002) Stat3 Controls Cell Movements during Zebrafish Gastrulation. Developmental Cell, 2 (3). pp. 363-375.