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Items where contributor is "Schier, Alexander"

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Montague, Tessa G. and Gagnon, James A. and Schier, Alexander F.. (2018) Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse. Development (Cambridge, England), 145 (24). p. 9.

Raj, Bushra and Gagnon, James A. and Schier, Alexander F.. (2018) Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT. Nature protocols, 13 (11). pp. 2685-2713.

Almuedo-Castillo, María and Bläßle, Alexander and Mörsdorf, David and Marcon, Luciano and Soh, Gary H. and Rogers, Katherine W. and Schier, Alexander F. and Müller, Patrick. (2018) Scale-invariant patterning by size-dependent inhibition of Nodal signalling. Nature cell biology, 20 (9). pp. 1032-1042.

Haesemeyer, Martin and Robson, Drew N. and Li, Jennifer M. and Schier, Alexander F. and Engert, Florian. (2018) A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. Neuron, 98 (4). pp. 817-831.e6.

Farrell, Jeffrey A. and Wang, Yiqun and Riesenfeld, Samantha J. and Shekhar, Karthik and Regev, Aviv and Schier, Alexander F.. (2018) Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. Science (New York, N.Y.), 360 (6392). p. 6.

Raj, Bushra and Wagner, Daniel E. and McKenna, Aaron and Pandey, Shristi and Klein, Allon M. and Shendure, Jay and Gagnon, James A. and Schier, Alexander F.. (2018) Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. Nature biotechnology, 36 (5). pp. 442-450.

Pandey, Shristi and Shekhar, Karthik and Regev, Aviv and Schier, Alexander F.. (2018) Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq. Current biology : CB, 28 (7). pp. 1052-1065.e7.

Gagnon, James A. and Obbad, Kamal and Schier, Alexander F.. (2018) The primary role of zebrafish nanog is in extra-embryonic tissue. Development (Cambridge, England), 145 (1). p. 9.

Rabani, Michal and Pieper, Lindsey and Chew, Guo-Liang and Schier, Alexander F.. (2017) A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell, 68 (6). pp. 1083-1094.e5.

Rogers, Katherine W. and Lord, Nathan D. and Gagnon, James A. and Pauli, Andrea and Zimmerman, Steven and Aksel, Deniz C. and Reyon, Deepak and Tsai, Shengdar Q. and Joung, J. Keith and Schier, Alexander F.. (2017) Nodal patterning without Lefty inhibitory feedback is functional but fragile. eLife, 6. 6:e28785.

Montague, Tessa G. and Schier, Alexander F.. (2017) Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm. eLife, 6. 6:e28183.

Norris, Megan L. and Pauli, Andrea and Gagnon, James A. and Lord, Nathan D. and Rogers, Katherine W. and Mosimann, Christian and Zon, Leonard I. and Schier, Alexander F.. (2017) Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. eLife, 6. 6:e22626.

Escamilla, Christine Ochoa and Filonova, Irina and Walker, Angela K. and Xuan, Zhong X. and Holehonnur, Roopashri and Espinosa, Felipe and Liu, Shunan and Thyme, Summer B. and López-García, Isabel A. and Mendoza, Dorian B. and Usui, Noriyoshi and Ellegood, Jacob and Eisch, Amelia J. and Konopka, Genevieve and Lerch, Jason P. and Schier, Alexander F. and Speed, Haley E. and Powell, Craig M.. (2017) Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature, 551 (7679). pp. 227-231.

Schoppik, David and Bianco, Isaac H. and Prober, David A. and Douglass, Adam D. and Robson, Drew N. and Li, Jennifer M. B. and Greenwood, Joel S. F. and Soucy, Edward and Engert, Florian and Schier, Alexander F.. (2017) Gaze-Stabilizing Central Vestibular Neurons Project Asymmetrically to Extraocular Motoneuron Pools. The Journal of Neuroscience, 37 (47). pp. 11353-11365.

Freyer, Laina and Hsu, Chih-Wei and Nowotschin, Sonja and Pauli, Andrea and Ishida, Junji and Kuba, Keiji and Fukamizu, Akiyoshi and Schier, Alexander F. and Hoodless, Pamela A. and Dickinson, Mary E. and Hadjantonakis, Anna-Katerina. (2017) Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell reports, 20 (9). pp. 2116-2130.

Hildebrand, David Grant Colburn and Cicconet, Marcelo and Torres, Russel Miguel and Choi, Woohyuk and Quan, Tran Minh and Moon, Jungmin and Wetzel, Arthur Willis and Scott Champion, Andrew and Graham, Brett Jesse and Randlett, Owen and Plummer, George Scott and Portugues, Ruben and Bianco, Isaac Henry and Saalfeld, Stephan and Baden, Alexander David and Lillaney, Kunal and Burns, Randal and Vogelstein, Joshua Tzvi and Schier, Alexander Franz and Lee, Wei-Chung Allen and Jeong, Won-Ki and Lichtman, Jeff William and Engert, Florian. (2017) Whole-brain serial-section electron microscopy in larval zebrafish. Nature, 545 (7654). pp. 345-349.

Thyme, Summer B. and Akhmetova, Laila and Montague, Tessa G. and Valen, Eivind and Schier, Alexander F.. (2016) Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature communications, 7. p. 11750.

McKenna, Aaron and Findlay, Gregory M. and Gagnon, James A. and Horwitz, Marshall S. and Schier, Alexander F. and Shendure, Jay. (2016) Whole-organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.), 353 (6298). aaf7907.

Chew, Guo-Liang and Pauli, Andrea and Schier, Alexander F.. (2016) Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish. Nature communications, 7. p. 11663.

Thyme, Summer B. and Schier, Alexander F.. (2016) Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell reports, 15 (4). pp. 707-714.

Li-Villarreal, Nanbing and Forbes, Meredyth M. and Loza, Andrew J. and Chen, Jiakun and Ma, Taylur and Helde, Kathryn and Moens, Cecilia B. and Shin, Jimann and Sawada, Atsushi and Hindes, Anna E. and Dubrulle, Julien and Schier, Alexander F. and Longmore, Gregory D. and Marlow, Florence L. and Solnica-Krezel, Lilianna. (2016) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development, 143 (10). p. 1832.

Dunn, Timothy W. and Mu, Yu and Narayan, Sujatha and Randlett, Owen and Naumann, Eva A. and Yang, Chao-Tsung and Schier, Alexander F. and Freeman, Jeremy and Engert, Florian and Ahrens, Misha B.. (2016) Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. eLife, 5. e12741.

Chiu, Cindy N. and Rihel, Jason and Lee, Daniel A. and Singh, Chanpreet and Mosser, Eric A. and Chen, Shijia and Sapin, Viveca and Pham, Uyen and Engle, Jae and Niles, Brett J. and Montz, Christin J. and Chakravarthy, Sridhara and Zimmerman, Steven and Salehi-Ashtiani, Kourosh and Vidal, Marc and Schier, Alexander F. and Prober, David A.. (2016) A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron, 89 (4). pp. 842-856.

Randlett, Owen and Wee, Caroline L. and Naumann, Eva A. and Nnaemeka, Onyeka and Schoppik, David and Fitzgerald, James E. and Portugues, Ruben and Lacoste, Alix M. B. and Riegler, Clemens and Engert, Florian and Schier, Alexander F.. (2015) Whole-brain activity mapping onto a zebrafish brain atlas. Nature Methods, 12 (11). pp. 1039-1046.

Haesemeyer, Martin and Robson, Drew N. and Li, Jennifer M. and Schier, Alexander F. and Engert, Florian. (2015) The structure and timescales of heat perception in larval zebrafish. Cell Systems, 1 (5). pp. 338-348.

Pauli, Andrea and Montague, Tessa G. and Lennox, Kim A. and Behlke, Mark A. and Schier, Alexander F.. (2015) Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PloS one, 10 (10). e0139504.

Li-Villarreal, Nanbing and Forbes, Meredyth M. and Loza, Andrew J. and Chen, Jiakun and Ma, Taylur and Helde, Kathryn and Moens, Cecilia B. and Shin, Jimann and Sawada, Atsushi and Hindes, Anna E. and Dubrulle, Julien and Schier, Alexander F. and Longmore, Gregory D. and Marlow, Florence L. and Solnica-Krezel, Lilianna. (2015) Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development, 142 (15). pp. 2704-2718.

Lacoste, Alix M. B. and Schoppik, David and Robson, Drew N. and Haesemeyer, Martin and Portugues, Ruben and Li, Jennifer M. and Randlett, Owen and Wee, Caroline L. and Engert, Florian and Schier, Alexander F.. (2015) A convergent and essential interneuron pathway for Mauthner-cell-mediated escapes. Current biology : CB, 25 (11). pp. 1526-1534.

Merkle, Florian T. and Neuhausser, Werner M. and Santos, David and Valen, Eivind and Gagnon, James A. and Maas, Kristi and Sandoe, Jackson and Schier, Alexander F. and Eggan, Kevin. (2015) Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus. Cell Reports , 11 (6). pp. 875-883.

Satija, Rahul and Farrell, Jeffrey A. and Gennert, David and Schier, Alexander F. and Regev, Aviv. (2015) Spatial reconstruction of single-cell gene expression data. Nature biotechnology, 33 (5). pp. 495-502.

Liu, Justin and Merkle, Florian T. and Gandhi, Avni V. and Gagnon, James A. and Woods, Ian G. and Chiu, Cindy N. and Shimogori, Tomomi and Schier, Alexander F. and Prober, David A.. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development, 142 (6). pp. 1113-1124.

Mundell, Nathan A. and Beier, Kevin T. and Pan, Y. Albert and Lapan, Sylvain W. and Göz Aytürk, Didem and Berezovskii, Vladimir K. and Wark, Abigail R. and Drokhlyansky, Eugene and Bielecki, Jan and Born, Richard T. and Schier, Alexander F. and Cepko, Constance L.. (2015) Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. Journal of Comparative Neurology, 523 (11). pp. 1639-1663.

Merkle, Florian T. and Maroof, Asif and Wataya, Takafumi and Sasai, Yoshiki and Studer, Lorenz and Eggan, Kevin and Schier, Alexander F.. (2015) Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England), 142 (4). pp. 633-643.

Rogers, Katherine W. and Blässle, Alexander and Schier, Alexander F. and Müller, Patrick. (2015) Measuring protein stability in living zebrafish embryos using fluorescence decay after photoconversion (FDAP). Journal of visualized experiments (95). e52266.

Haesemeyer, Martin and Schier, Alexander F.. (2015) The study of psychiatric disease genes and drugs in zebrafish. Current Opinion in Neurobiology, 30. pp. 122-130.

Pauli, Andrea and Valen, Eivind and Schier, Alexander F.. (2015) Identifying (non-)coding RNAs and small peptides: challenges and opportunities. BioEssays : news and reviews in molecular, cellular and developmental biology, 37 (1). pp. 103-112.