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Items where contributor is "Schaeren-Wiemers, Nicole"

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2017

Herrendorff, Ruben and Hänggi, Pascal and Pfister, Hélène and Yang, Fan and Demeestere, Delphine and Hunziker, Fabienne and Frey, Samuel and Schaeren-Wiemers, Nicole and Steck, Andreas J. and Ernst, Beat. (2017) Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy. Proceedings of the National Academy of Sciences, 114 (18). E3689-E3698.

2016

Zeis, Thomas and Enz, Lukas and Schaeren-Wiemers, Nicole. (2016) The immunomodulatory oligodendrocyte. Brain Research, 1641. pp. 139-148.

Ritz, Marie-Françoise and Grond-Ginsbach, Caspar and Kloss, Manja and Tolnay, Markus and Fluri, Felix and Bonati, Leo H. and Traenka, Christopher and Zeis, Thomas and Schaeren-Wiemers, Nicole and Peters, Nils and Engelter, Stefan Thomas and Lyrer, Philippe Alexandre. (2016) Identification of Inflammatory, Metabolic, and Cell Survival Pathways Contributing to Cerebral Small Vessel Disease by Postmortem Gene Expression Microarray. Current Neurovascular Research , 13 (1). pp. 58-67.

2015

Linden, Jennifer R. and Ma, Yinghua and Zhao, Baohua and Harris, Jason Michael and Rumah, Kareem Rashid and Schaeren-Wiemers, Nicole and Vartanian, Timothy. (2015) Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination. mBio, 6 (3). e02513.

Lindner, Maren and Thümmler, Katja and Arthur, Ariel and Brunner, Sarah and Elliott, Christina and McElroy, Daniel and Mohan, Hema and Williams, Anna and Edgar, Julia M. and Schuh, Cornelia and Stadelmann, Christine and Barnett, Susan C. and Lassmann, Hans and Mücklisch, Steve and Mudaliar, Manikhandan and Schaeren-Wiemers, Nicole and Meinl, Edgar and Linington, Christopher. (2015) Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9. Brain, 138 (7). pp. 1875-1893.

Fluri, Felix and Grünstein, Dan and Cam, Ertugrul and Ungethuem, Udo and Hatz, Florian and Schäfer, Juliane and Samnick, Samuel and Israel, Ina and Kleinschnitz, Christoph and Orts-Gil, Guillermo and Moch, Holger and Zeis, Thomas and Schaeren-Wiemers, Nicole and Seeberger, Peter. (2015) Fullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats. Experimental Neurology, 265. pp. 142-151.

Lossos, Alexander and Elazar, Nimrod and Lerer, Israela and Schueler-Furman, Ora and Fellig, Yakov and Glick, Benjamin and Zimmerman, Bat-El and Azulay, Haim and Dotan, Shlomo and Goldberg, Sharon and Gomori, John M. and Ponger, Penina and Newman, J. P. and Marreed, Hodaifah and Steck, Andreas J. and Schaeren-Wiemers, Nicole and Mor, Nofar and Harel, Michal and Geiger, Tamar and Eshed-Eisenbach, Yael and Meiner, Vardiella and Peles, Elior. (2015) Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder. Brain : a journal of neurology, 138 (Pt 9). pp. 2521-2536.

Perriard, Guillaume and Mathias, Amandine and Enz, Lukas and Canales, Mathieu and Schluep, Myriam and Gentner, Melanie and Schaeren-Wiemers, Nicole and Du Pasquier, Renaud A.. (2015) Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes. Journal of Neuroinflammation, 12. p. 119.

Rumah, Kareem Rashid and Ma, Yinghua and Linden, Jennifer R. and Oo, Myat Lin and Anrather, Josef and Schaeren-Wiemers, Nicole and Alonso, Miguel A. and Fischetti, Vincent A. and McClain, Mark S. and Vartanian, Timothy. (2015) The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin. PLoS pathogens, 11 (5). e1004896.

Zeis, T. and Allaman, I. and Gentner, M. and Schroder, K. and Tschopp, J. and Magistretti, P. J. and Schaeren-Wiemers, N.. (2015) Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling. Brain, Behavior, and Immunity, 48. pp. 313-325.

2012

Tchorz, J. S. and Tome, M. and Cloetta, D. and Sivasankaran, B. and Grzmil, M. and Huber, R. M. and Rutz-Schatzmann, F. and Kirchhoff, F. and Schaeren-Wiemers, N. and Gassmann, M. and Hemmings, B. A. and Merlo, A. and Bettler, B.. (2012) Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry. Cell death & disease, Vol. 3 , e325.

Zhou, G. and Liang, F. X. and Romih, R. and Wang, Z. and Liao, Y. and Ghiso, J. and Luque-Garcia, J. L. and Neubert, T. A. and Kreibich, G. and Alonso, M. A. and Schaeren-Wiemers, N. and Sun, T. T.. (2012) MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells. Molecular Biology of the Cell, 23 (7). pp. 1354-1366.

Takiar, V. and Mistry, K. and Carmosino, M. and Schaeren-Wiemers, N. and Caplan, M. J.. (2012) VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis. American journal of physiology. Cell Physiology, Vol. 303, H. 8 , C862-C871.

Kinter, J. and Lazzati, T. and Schmid, D. and Zeis, T. and Erne, B. and Lutzelschwab, R. and Steck, A. J. and Pareyson, D. and Peles, E. and Schaeren-Wiemers, N.. (2012) An essential role of MAG in mediating axon-myelin attachment in Charcot-Marie-Tooth 1A disease. Neurobiology of disease, Vol. 49. pp. 221-231.

2011

Metz, M. and Gassmann, M. and Fakler, B. and Schaeren-Wiemers, N. and Bettler, B.. (2011) Distribution of the auxiliary GABA(B) receptor subunits KCTD8, 12, 12b and 16 in the mouse brain. The journal of comparative neurology, Vol. 519, H. 8. pp. 1435-1454.

Siegmund, Kerstin and Zeis, Thomas and Kunz, Gabriele and Rolink, Ton and Schaeren-Wiemers, Nicole and Pieters, Jean. (2011) Coronin 1-Mediated Naive T Cell Survival Is Essential for the Development of Autoimmune Encephalomyelitis. Journal of Immunology, 186 (6). pp. 3452-3461.

Pfeiffer, F. and Schafer, J. and Lyck, R. and Makrides, V. and Brunner, S. and Schaeren-Wiemers, N. and Deutsch, U. and Engelhardt, B.. (2011) Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis. Acta neuropathologica, Vol. 122, no. 5. pp. 601-614.

2010

Rauskolb, Stefanie and Zagrebelsky, Marta and Dreznjak, Anita and Deogracias, Rubén and Matsumoto, Tomoya and Wiese, Stefan and Erne, Beat and Sendtner, Michael and Schaeren-Wiemers, Nicole and Korte, Martin and Barde, Yves-Alain. (2010) Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. Journal of Neuroscience, 30 (5). pp. 1739-1749.

Kinter, Jochen and Broglio, Laura and Steck, Andreas J. and Tolnay, Markus and Fuhr, Peter and Latov, Norman and Kalbermatten, Daniel and Sinnreich, Michael and Schaeren-Wiemers, Nicole and Renaud, Susanne. (2010) Gene expression profiling in nerve biopsy of vasculitic neuropathy. Journal of neuroimmunology, Vol. 225, H. 1-2. pp. 184-189.

Carmosino, Monica and Rizzo, Federica and Procino, Giuseppe and Basco, Davide and Valenti, Giovanna and Forbush, Biff and Schaeren-Wiemers, Nicole and Caplan, Michael J. and Svelto, Maria. (2010) MAL/VIP17, a new player in the regulation of NKCC2 in the kidney. Molecular Biology of the Cell, 21 (22). pp. 3985-3997.

2009

Buser, A. M. and Erne, B. and Werner, H. B. and Nave, K.-A. and Schaeren-Wiemers, N.. (2009) The septin cytoskeleton in myelinating glia. Molecular and cellular neuroscience : MCN, Vol. 40, H. 2. pp. 156-166.

Ritz, Marie-Françoise and Fluri, Felix and Engelter, Stefan T. and Schaeren-Wiemers, Nicole and Lyrer, Philippe A.. (2009) Cortical and putamen age-related changes in the microvessel density and astrocyte deficiency in spontaneously hypertensive and stroke-prone spontaneously hypertensive rats. Current neurovascular research, Vol. 6, H. 4. pp. 279-287.

Stalder, Anna K. and Erne, Beat and Reimann, Regina and Renaud, Susanne and Fuhr, Peter and Thomann, Sandra and Arnold, Andreas and Probst, Alphonse and Schaeren-Wiemers, Nicole and Steck, Andreas J.. (2009) Immunoglobulin M deposition in cutaneous nerves of anti-myelin-associated glycoprotein polyneuropathy patients correlates with axonal degeneration. Journal of neuropathology and experimental neurology : official journal of the American Association of Neuropathologists (AANP), Vol. 68, H. 2. pp. 148-158.

Buser, A. M. and Schmid, D. and Kern, F. and Erne, B. and Lazzati, T. and Schaeren-Wiemers, N.. (2009) The myelin protein MAL affects peripheral nerve myelination : a new player influencing p75 neurotrophin receptor expression. The European journal of neuroscience : EJN, Vol. 29, H. 12. pp. 2276-2290.

2008

Zeis, T. and Kinter, J. and Herrero-Herranz, E. and Weissert, R. and Schaeren-Wiemers, N.. (2008) Gene expression analysis of normal appearing brain tissue in an animal model for multiple sclerosis revealed grey matter alterations, but only minor white matter changes. Journal of neuroimmunology, Vol. 205, H. 1-2. pp. 10-19.

Broglio, L. and Erne, B. and Tolnay, M. and Schaeren-Wiemers, N. and Fuhr, P. and Steck, A. J. and Renaud, S.. (2008) Allograft inflammatory factor-1: a pathogenetic factor for vasculitic neuropathy. Muscle & nerve, Vol. 38. pp. 1272-1279.

Zeis, Thomas and Probst, Alfonse and Steck, Andreas Johann and Stadelmann, Christine and Brück, Wolfgang and Schaeren-Wiemers, Nicole. (2008) Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis. Brain pathology, Vol. 19, no. 3. pp. 459-466.

Zeis, T. and Graumann, U. and Reynolds, R. and Schaeren-Wiemers, N.. (2008) Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. Brain, Vol. 131, H. 1. pp. 288-303.

Kinter, J. and Zeis, T. and Schaeren-Wiemers, N.. (2008) RNA profiling of MS brain tissues. The international MS journal, Vol. 15, H. 2. pp. 51-58.

Zeis, T. and Schaeren-Wiemers, N.. (2008) Lame ducks or fierce creatures? : The role of oligodendrocytes in multiple sclerosis. Journal of molecular neuroscience, Vol. 35, No. 1. pp. 91-100.

2006

Steck, Andreas J. and Erne, Beat and Pareyson, Davide and Sghirlanzoni, Angelo and Taroni, Franco and Schaeren-Wiemers, Nicole. (2006) Normal expression of myelin protein zero with frame-shift mutation correlates with mild phenotyp. Journal of the peripheral nervous system : JPNS, Vol. 11, H. 1. pp. 61-66.

Erb, Michael and Flueck, Bettina and Kern, Frances and Erne, Beat and Steck, Andreas J. and Schaeren-Wiemers, Nicole. (2006) Unraveling the differential expression of the two isoforms of myelin-associated glycoprotein in a mouse expressing GFP-tagged S-MAG specifically regulated and targeted into the different myelin compartments. Molecular and cellular neuroscience, Vol. 31, H. 4. pp. 613-627.

2005

Schaeren-Wiemers, N.. (2005) [Endogenous neuroprotective mechanisms in multiple sclerosis]. Schweizerische Rundschau für Medizin Praxis, Jg. 94, Nr. 6. pp. 205-208.

Fewou, Simon N. and Büssow, Heinrich and Schaeren-Wiemers, Nicole and Vanier, Marie T. and Macklin, Wendy B. and Gieselmann, Volkmar and Eckhardt, Matthias. (2005) Reversal of non-hydroxy:alpha-hydroxy galactosylceramide ratio and unstable myelin in transgenic mice overexpressing UDP-galactose:ceramide galactosyltransferase. Journal of neurochemistry, Vol. 94, H. 2. pp. 469-481.

Lombardi, Raffaella and Erne, Beat and Lauria, Giuseppe and Pareyson, Davide and Borgna, Monica and Morbin, Michela and Arnold, Andreas and Czaplinski, Adam and Fuhr, Peter and Schaeren-Wiemers, Nicole and Steck, Andreas J.. (2005) IgM deposits on skin nerves in anti-myelin-associated glycoprotein neuropathy. Annals of neurology, Vol. 57, H. 2. pp. 180-187.

2004

Schaeren-Wiemers, Nicole and Bonnet, Annick and Erb, Michael and Erne, Beat and Bartsch, Udo and Kern, Frances and Mantei, Ned and Sherman, Diane and Suter, Ueli. (2004) The raft-associated protein MAL is required for maintenance of proper axon--glia interactions in the central nervous system. The Journal of cell biology, Vol. 166, H. 5. pp. 731-742.

Saravanan, K. and Schaeren-Wiemers, N. and Klein, D. and Sandhoff, R. and Schwarz, A. and Yaghootfam, A. and Gieselmann, V. and Franken, S.. (2004) Specific downregulation and mistargeting of the lipid raft-associated protein MAL in a glycolipid storage disorder. Neurobiology of disease, Vol. 16, no. 2. pp. 396-406.

2003

Erb, M. and Steck, A. J. and Nave, K. A. and Schaeren-Wiemers, N.. (2003) Differential expression of L- and S-MAG upon cAMP stimulated differentiation in oligodendroglial cells. Journal of neuroscience research, Vol. 71, No. 3. pp. 326-337.

Graumann, Ursula and Reynolds, Richard and Steck, Andreas J. and Schaeren-Wiemers, Nicole. (2003) Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult. Brain pathology, Vol. 13, no. 4. pp. 554-573.

Gieselmann, V. and Franken, S. and Klein, D. and Mansson, J. E. and Sandhoff, R. and Lüllmann Rauch, R. and Hartmann, D. and Saravanan, V. P. M. and De Deyn, P. P. and D'Hooge, R. and Van Der Linden, A. M. and Schaeren-Wiemers, N.. (2003) Metachromatic leukodystrophy: consequences of sulphatide accumulation. Acta paediatrica. Supplement, Vol. 92, H. 443 , S. 74-79; discussion 45.

2002

Erne, B. and Sansano, S. and Frank, M. and Schaeren-Wiemers, N.. (2002) Rafts in adult peripheral nerve myelin contain major structural myelin proteins and myelin and lymphocyte protein (MAL) and CD59 as specific markers. Journal of neurochemistry, Vol. 82, H. 3. pp. 550-562.

Sollberger, M. and Erne, B. and Sansano, S. and Steck, A. J. and Schaeren-Wiemers, N.. (2002) Characterization of human nerve basal lamina for their binding properties of anti-MAG antibodies. Journal of neurocytology, Vol. 31, H. 1. pp. 5-14.

1996

Moll, S. and Schaeren-Wiemers, N. and Wohlwend, A. and Pastore, Y. and Fulpius, T. and Monard, D. and Sappino, A. P. and Schifferli, J. A. and Vassalli, J. D. and Izui, S.. (1996) Protease nexin 1 in the murine kidney: glomerular localization and up-regulation in glomerulopathies. Kidney international, 50 (6). pp. 1936-1945.

Holz, A. and Schaeren-Wiemers, N. and Schaefer, C. and Pott, U. and Colello, R. J. and Schwab, M. E.. (1996) Molecular and developmental characterization of novel cDNAs of the myelin-associated/oligodendrocytic basic protein. Journal of Neuroscience, 16 (2). pp. 467-477.

1995

Schaeren-Wiemers, N. and van der Bijl, P. and Schwab, M. E.. (1995) The UDP-galactose:ceramide galactosyltransferase: expression pattern in oligodendrocytes and Schwann cells during myelination and substrate preference for hydroxyceramide. Journal of Neurochemistry, 65 (5). pp. 2267-2278.

Schaeren-Wiemers, N. and Valenzuela, D. M. and Frank, M. and Schwab, M. E.. (1995) Characterization of a rat gene, rMAL, encoding a protein with four hydrophobic domains in central and peripheral myelin. Journal of Neuroscience, 15 (8). pp. 5753-5764.

Schaeren-Wiemers, N. and Schaefer, C. and Valenzuela, D. M. and Yancopoulos, G. D. and Schwab, M. E.. (1995) Identification of new oligodendrocyte- and myelin-specific genes by a differential screening approach. Journal of Neurochemistry, 65 (1). pp. 10-22.

1994

Becker-André, M. and Wiesenberg, I. and Schaeren-Wiemers, N. and André, E. and Missbach, M. and Saurat, J. H. and Carlberg, C.. (1994) Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily. Journal of Biological Chemistry, 269 (46). pp. 28531-28534.

1993

Schaeren-Wiemers, N. and Gerfin-Moser, A.. (1993) A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry, 100 (6). pp. 431-440.

1991

Pott, U. and Schaeren-Wiemers, N. and Schaefer, C. and Schwab, M. E.. (1991) A molecular biological approach to the regulation of oligodendrocyte differentiation. Schweizer Archiv für Neurologie und Psychiatrie, 142 (2). pp. 123-126.

1989

Trüeb, B. and Schaeren-Wiemers, N. and Schreier, T. and Winterhalter, K. H.. (1989) Molecular cloning of chicken type VI collagen. Primary structure of the subunit alpha 2(VI)-pepsin. Journal of Biological Chemistry, 264 (1). pp. 136-140.