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Items where contributor is "Penny, Melissa"

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2022

Ali, A. M. and Gausi, K. and Jongo, S. A. and Kassim, K. R. and Mkindi, C. and Simon, B. and Mtoro, A. T. and Juma, O. A. and Lweno, O. N. and Gwandu, C. H. and Bakari, B. M. and Mbaga, T. A. and Milando, F. A. and Hamad, A. and Shekalaghe, S. A. and Abdulla, S. and Denti, P. and Penny, M. A.. (2022) Population pharmacokinetics of antimalarial naphthoquine in combination with artemisinin in Tanzanian children and adults: dose optimization. Antimicrob Agents Chemother, 66 (5). e0169621.

Golumbeanu, M. and Yang, G. J. and Camponovo, F. and Stuckey, E. M. and Hamon, N. and Mondy, M. and Rees, S. and Chitnis, N. and Cameron, E. and Penny, M. A.. (2022) Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions. Infect Dis Poverty, 11. p. 61.

Kelly, S. L. and Le Rütte, E. A. and Richter, M. and Penny, M. A. and Shattock, A. J.. (2022) COVID-19 vaccine booster strategies in light of emerging viral variants: frequency, timing, and target groups. Infect Dis Ther, 11 (5). pp. 2045-2061.

Le Rütte, E. A. and Shattock, A. J. and Chitnis, N. and Kelly, S. L. and Penny, M. A.. (2022) Modelling the impact of Omicron and emerging variants on SARS-CoV-2 transmission and public health burden. Commun Med (Lond), 2. p. 93.

Lee, T. E. and Bonhoeffer, S. and Penny, M. A.. (2022) The competition dynamics of resistant and sensitive infections. Results Phys, 34. p. 105181.

Masserey, T. and Lee, T. and Golumbeanu, M. and Shattock, A. J. and Kelly, S. L. and Hastings, I. M. and Penny, M. A.. (2022) The influence of biological, epidemiological, and treatment factors on the establishment and spread of drug-resistant Plasmodium falciparum. eLife, 11. e7763.

Masserey, T. and Penny, M. A. and Lee, T. E.. (2022) Patient variability in the blood-stage dynamics of Plasmodium falciparum captured by clustering historical data. Malar J, 21. p. 300.

Watson, O. J. and Gao, B. and Nguyen, T. D. and Tran, T. N. and Penny, M. A. and Smith, D. L. and Okell, L. and Aguas, R. and Boni, M. F.. (2022) Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus modelling study. Lancet Microbe, 3 (9). e701-e710.

Yang, G. J. and Shang, L. Y. and Zhou, X. N. and Lee, T. E. and Bi, B. and White, M. and Smith, T. A. and Penny, M. A.. (2022) The empirical support for the radical cure strategy for eliminating Plasmodium vivax in China. BMC Med, 20. p. 17.

Nekkab, N. and Penny, M. A.. (2022) Accelerated development of malaria monoclonal antibodies. Cell Rep Med, 3 (10). p. 100786.

2021

Camponovo, F. and Lee, T. E. and Russell, J. R. and Burgert, L. and Gerardin, J. and Penny, M. A.. (2021) Mechanistic within-host models of the asexual; Plasmodium falciparum; infection: a review and analytical assessment. Malar J, 20. p. 309.

Burgert, L. and Zaloumis, S. and Dini, S. and Marquart, L. and Cao, P. and Cherkaoui, M. and Gobeau, N. and McCarthy, J. and Simpson, J. A. and Möhrle, J. J. and Penny, M. A.. (2021) Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance. Antimicrobial agents and chemotherapy, 65 (4). e01539-20.

Reiker, T. and Golumbeanu, M. and Shattock, A. and Burgert, L. and Smith, T. A. and Filippi, S. and Cameron, E. and Penny, M. A.. (2021) Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria. Nat Commun, 12. p. 7212.

Stader, F. and Courlet, P. and Kinvig, H. and Penny, M. A. and Decosterd, L. A. and Battegay, M. and Siccardi, M. and Marzolini, C.. (2021) Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly. Clin Pharmacol Ther, 109 (2). pp. 471-484.

Stader, F. and Courlet, P. and Kinvig, H. and Battegay, M. and Decosterd, L. A. and Penny, M. A. and Siccardi, M. and Marzolini, C.. (2021) Effect of ageing on antiretroviral drug pharmacokinetics using clinical data combined with modelling and simulation. Br J Clin Pharmacol, 87 (2). pp. 458-470.

Shattock, A. J. and Le Rütte, E. A. and Dünner, R. P. and Sen, S. and Kelly, S. L. and Chitnis, N. and Penny, M. A.. (2021) Impact of vaccination and non-pharmaceutical interventions on SARS-CoV-2 dynamics in Switzerland. Epidemics, 38. p. 100535.

Galactionova, K. and Smith, T. A. and Penny, M. A.. (2021) Insights from modelling malaria vaccines for policy decisions: the focus on RTS,S. Malar J, 20. p. 439.

2020

Burgert, Lydia and Rottmann, Matthias and Wittlin, Sergio and Gobeau, Nathalie and Krause, Andreas and Dingemanse, Jasper and Möhrle, Jörg J. and Penny, Melissa A.. (2020) Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development. Scientific reports, 10. p. 4410.

Penny, Melissa A. and Camponovo, Flavia and Chitnis, Nakul and Smith, Thomas A. and Tanner, Marcel. (2020) Future use-cases of vaccines in malaria control and elimination. Parasite epidemiology and control, 10. e00145.

Camponovo, Flavia and Campo, Joseph J. and Le, Timothy Q. and Oberai, Amit and Hung, Christopher and Pablo, Jozelyn V. and Teng, Andy A. and Liang, Xiaowu and Sim, B. Kim Lee and Jongo, Said and Abdulla, Salim and Tanner, Marcel and Hoffman, Stephen L. and Daubenberger, Claudia and Penny, Melissa A.. (2020) Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults. eLife, 9. e53080.

Galactionova, Katya and Velarde, Mar and Silumbe, Kafula and Miller, John and McDonnell, Anthony and Aguas, Ricardo and Smith, Thomas A. and Penny, Melissa A.. (2020) Costing malaria interventions from pilots to elimination programmes. Malaria journal, 19. p. 332.

Yang, G. J. and Liu, Y. and Shang, L. Y. and Zhang, H. W. and Zhou, X. N. and Penny, M. A. and Smith, T. A.. (2020) From Plasmodium vivax outbreak to elimination: lessons learnt from a retrospective analysis of data from Guantang. Malar J, 19. p. 427.

2019

Lee, Tamsin E. and Penny, Melissa A.. (2019) Identifying key factors of the transmission dynamics of drug-resistant malaria. Journal of theoretical biology, 462. pp. 210-220.

Stader, Felix and Penny, Melissa A. and Siccardi, Marco and Marzolini, Catia. (2019) A comprehensive framework for physiologically based pharmacokinetic modelling in Matlab. CPT: Pharmacometrics & Systems Pharmacology. NA.

Meister, Isabel and Assawasuwannakit, Piyanan and Vanobberghen, Fiona and Penny, Melissa A. and Odermatt, Peter and Sayasone, Somphou and Huwyler, Jörg and Tarning, Joel and Keiser, Jennifer. (2019) Pooled population pharmacokinetic analysis of tribendimidine for the treatment of Opisthorchis viverrini infections. Antimicrobial Agents and Chemotherapy, 63 (4). e01391-18.

Dietler, Dominik and Leuenberger, Andrea and Bempong, Nefti-Eboni and Campbell-Lendrum, Diarmid and Cramer, Conradin and Eggen, Rik I. L. and Erismann, Séverine and Ferazzi, Silvia and Flahault, Antoine and Fletcher, Helen A. and Fuhrer, Bernhard and Fuhrimann, Samuel and Greter, Helena and Heerdegen, Anne Christine and Leach, Melissa and Leissing, Anna and Lilje, Jonathan and Penny, Melissa A. and Prytherch, Helen and Staudacher, Philipp and Vounatsou, Penelope and Weiss, Frederik and Wiedemann, Ruth and Winkler, Mirko S. and Zhou, Xiao-Nong and Utzinger, Jürg. (2019) Health in the 2030 Agenda for Sustainable Development : from framework to action, transforming challenges into opportunities. Journal of global health, 9 (2). 020201.

Camponovo, Flavia and Ockenhouse, Chris F. and Lee, Cynthia and Penny, Melissa A.. (2019) Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a modelling study. BMC infectious diseases, 19. p. 920.

Smith, T. A. and Pemberton-Ross , P. and Penny, M. A. and Chitnis, N.. (2019) Resurgence of malaria infection after mass treatment: a simulation study. Malaria journal, 18. p. 409.

2018

Chitnis, Nakul and Schapira, Allan and Schindler, Christian and Penny, Melissa A. and Smith, Thomas A.. (2018) Mathematical analysis to prioritise strategies for malaria elimination. Journal of theoretical biology, 455. pp. 118-130.

Ali, Ali Mohamed and Penny, Melissa A. and Smith, Thomas A. and Workman, Lesley and Sasi, Philip and Adjei, George O. and Aweeka, Francesca and Kiechel, Jean-René and Jullien, Vincent and Rijken, Marcus J. and McGready, Rose and Mwesigwa, Julia and Kristensen, Kim and Stepniewska, Kasia and Tarning, Joel and Barnes, Karen I. and Denti, Paolo and Wwarn Amodiaquine PK Study Group, . (2018) Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing. Antimicrobial agents and chemotherapy, 62 (10). e02193-17.

Stader, Felix and Siccardi, Marco and Battegay, Manuel and Kinvig, Hannah and Penny, Melissa A. and Marzolini, Catia. (2018) Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes. Clinical pharmacokinetics. NA.

2017

Camponovo, Flavia and Bever, Caitlin A. and Galactionova, Katya and Smith, Thomas and Penny, Melissa A.. (2017) Incidence and admission rates for severe malaria and their impact on mortality in Africa. Malaria journal, 16. p. 1.

Galactionova, Katya and Tediosi, Fabrizio and Camponovo, Flavia and Smith, Thomas A. and Gething, Peter W. and Penny, Melissa A.. (2017) Country specific predictions of the cost-effectiveness of malaria vaccine RTS,S/AS01 in endemic Africa. Vaccine, 35 (1). pp. 53-60.

Smith, T. and Chitnis, N. and Penny, M.. (2017) Predictive malaria epidemiology : modeling malaria infection dynamics and impact of control interventions. In: Encyclopedia of malaria. New York, pp. 1-10.

Smith, Thomas A. and Chitnis, Nakul and Penny, Melissa and Tanner, Marcel. (2017) Malaria modeling in the era of eradication. Cold Spring Harbor perspectives in medicine, 7 (4). a025460.

Brady, Oliver J. and Slater, Hannah C. and Pemberton-Ross, Peter James and Wenger, Edward and Maude, Richard J. and Ghani, Azra C. and Penny, Melissa A. and Gerardin, Jaline and White, Lisa J. and Chitnis, Nakul and Aguas, Ricardo and Hay, Simon I. and Smith, David L. and Stuckey, Erin M. and Okiro, Emelda A and Smith, Thomas A. and Okell, Lucy C.. (2017) Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study. Lancet Glob Health, 5 (7). e680-e687.

Brady, O. J. and Slater, H. C. and Pemberton-Ross, P. and Wenger, E. and Maude, R. J. and Ghani, A. C. and Penny, M. A. and Gerardin, J. and White, L. J. and Chitnis, N. and Aguas, R. and Hay, S. I. and Smith, D. L. and Stuckey, E. M. and Smith, T. A. and Okell, L. C.. (2017) Model citizen – Authors' reply. Lancet. Global health, 5 (10). e974.

Galactionova, Katya and Smith, Thomas A. and de Savigny, Don and Penny, Melissa A.. (2017) State of inequality in malaria intervention coverage in sub-Saharan African countries. BMC medicine, 15. p. 185.

Penny, Melissa and Smith, Thomas. (2017) Plasmodium falciparum mortality in Africa between 1990 and 2015. The New England Journal of Medicine, 376. pp. 2493-2494.

2016

Penny, Melissa A. and Verity, Robert and Bever, Caitlin A. and Sauboin, Christophe and Galactionova, Katya and Flasche, Stefan and White, Michael T. and Wenger, Edward A. and Van de Velde, Nicolas and Pemberton-Ross, Peter and Griffin, Jamie T. and Smith, Thomas A. and Eckhoff, Philip A. and Muhib, Farzana and Jit, Mark and Ghani, Azra C.. (2016) Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine : a systematic comparison of predictions from four mathematical models. Lancet, 387 (10016). pp. 367-375.

Tediosi, F. and Penny, M.. (2016) Evidence for optimal allocation of malaria interventions in Africa. Lancet. Global health, 4 (7). e432-e433.

Duthaler, Urs and Sayasone, Somphou and Vanobbergen, Fiona and Penny, Melissa A. and Odermatt, Peter and Huwyler, Jörg and Keiser, Jennifer. (2016) Single-ascending-Ddse pharmacokinetic study of tribendimidine in opisthorchis viverrini-infected patients. Antimicrobial Agents and Chemotherapy, 60 (10). pp. 5705-5715.

Vanobberghen, Fiona and Penny, Melissa A. and Duthaler, Urs and Odermatt, Peter and Sayasone, Somphou and Keiser, Jennifer and Tarning, Joel. (2016) Population pharmacokinetic modeling of tribendimidine metabolites in opisthorchis viverrini-Infected adults. Antimicrobial agents and chemotherapy, 60 (10). pp. 5695-5704.

Duthaler, Urs and Sayasone, Somphou and Vanobbergen, Fiona and Penny, Melissa A. and Odermatt, Peter and Huwyler, Jörg and Keiser, Jennifer. (2016) Single ascending dose pharmacokinetic study of tribendimidine in Opisthorchis viverrini-infected patients. Antimicrobial agents and chemotherapy, 60 (10). pp. 5705-5715.

2015

Penny, Melissa A. and Galactionova, Katya and Tarantino, Michael and Tanner, Marcel and Smith, Thomas A.. (2015) The public health impact of malaria vaccine RTS,S in malaria endemic Africa : country-specific predictions using 18 month follow-up Phase III data and simulation models. BMC medicine, Vol. 13 , 170.

Pemberton-Ross, Peter and Smith, Thomas A. and Hodel, Eva Maria and Kay, Katherine and Penny, Melissa A.. (2015) Age-shifting in malaria incidence as a result of induced immunological deficit : a simulation study. Malaria journal, Vol. 14 , 287.

Cameron, Ewan and Battle, Katherine E. and Bhatt, Samir and Weiss, Daniel J. and Bisanzio, Donal and Mappin, Bonnie and Dalrymple, Ursula and Hay, Simon I. and Smith, David L. and Griffin, Jamie T. and Wenger, Edward A. and Eckhoff, Philip A. and Smith, Thomas A. and Penny, Melissa A. and Gething, Peter W.. (2015) Defining the relationship between infection prevalence and clinical incidence of Plasmodium falciparum malaria. Nature communications, Vol. 6 , Article Nr. 8170.

Penny, Melissa A. and Maire, Nicolas and Bever, Caitlin A. and Pemberton-Ross, Peter and Briët, Olivier J. T. and Smith, David L. and Gething, Peter W. and Smith, Thomas A.. (2015) Distribution of malaria exposure in endemic countries in Africa considering country levels of effective treatment. Malaria journal, Vol. 14 , 384.

Penny, Melissa A. and Pemberton-Ross, Peter and Smith, Thomas A.. (2015) The time-course of protection of the RTS,S vaccine against malaria infections and clinical disease. Malaria journal, 14. p. 437.

Bhatt, S. and Weiss, D. J. and Cameron, E. and Bisanzio, D. and Mappin, B. and Dalrymple, U. and Battle, K. E. and Moyes, C. L. and Henry, A. and Eckhoff, P. A. and Wenger, E. A. and Briët, O. and Penny, M. A. and Smith, T. A. and Bennett, A. and Yukich, J. and Eisele, T. P. and Griffin, J. T. and Fergus, C. A. and Lynch, M. and Lindgren, F. and Cohen, J. M. and Murray, C. L. J. and Smith, D. L. and Hay, S. I. and Cibulskis, R. E. and Gething, P. W.. (2015) The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature, 526 (7572). pp. 207-211.

Okell, L. and Slater, H. and Ghani, A. and Pemberton-Ross, P. and Smith, T. A. and Chitnis, N. and Penny, M. A. and Wenger, E. and Garardin, J. and Maude, R. and Aguas, R. and White, L. and Brady, O. and Hay, S. and Okiro, E. and Kern, S.. (2015) Consensus modelling evidence to support the design of mass drug administration programmes. Malaria Policy Advisory Committee meeting, 16-18 September 2015, Geneva Switzerland, Background document for Session 1. Geneva.

2013

Briët, Olivier Jt and Penny, Melissa A. and Hardy, Diggory and Awolola, Taiwo S. and Van Bortel, Wim and Corbel, Vincent and Dabiré, Roch K. and Etang, Josiane and Koudou, Benjamin G. and Tungu, Patrick K. and Chitnis, Nakul. (2013) Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets : a modelling study. Malaria journal, Vol. 12 , 77.