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Items where contributor is "Nashev, Lyubomir Georgiev"

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2013

Legeza, Balázs and Balázs, Zoltán and Nashev, Lyubomir G. and Odermatt, Alex. (2013) The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase. Endocrinology, Vol. 154, H. 1. pp. 205-213.

2012

Nashev, Lyubomir G. and Vuorinen, Anna and Praxmarer, Lukas and Chantong, Boonrat and Cereghetti, Diego and Winiger, Rahel and Schuster, Daniela and Odermatt, Alex. (2012) Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action. PLoS ONE, Vol. 7, H. 10 , e46958.

Chantong, Boonrat and Kratschmar, Denise V. and Nashev, Lyubomir G. and Balazs, Zoltan and Odermatt, Alex. (2012) Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of neuroinflammation, Vol. 9. p. 260.

2010

Nashev, Lyubomir G. and Schuster, Daniela and Laggner, Christian and Sodha, Seloni and Langer, Thierry and Wolber, Gerhard and Odermatt, Alex. (2010) The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3 : virtual screening as a strategy to identify potential endocrine disrupting chemicals. Biochemical Pharmacology, Vol. 79, Issue 8. pp. 1189-1199.

2009

Balazs, Z. and Nashev, L. G. and Chandsawangbhuwana, C. and Baker, M. E. and Odermatt, A.. (2009) Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1. Molecular and cellular endocrinology, Vol. 301, H. 1-2. pp. 117-122.

Dzyakanchuk, A. A. and Balazs, Z. and Nashev, L. G. and Amrein, K. E. and Odermatt, A.. (2009) 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose. Molecular and cellular endocrinology, Vol. 301, H. 1-2. pp. 137-141.

2008

Schuster, Daniela and Nashev, Lyubomir G. and Kirchmair, Johannes and Laggner, Christian and Wolber, Gerhard and Langer, Thierry and Odermatt, Alex. (2008) Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. Journal of medicinal chemistry, Vol. 51, no. 14. pp. 4188-4199.

Atanasov, Atanas G. and Nashev, Lyubomir G. and Gelman, Laurent and Legeza, Balazs and Sack, Ragna and Portmann, Reto and Odermatt, Alex. (2008) Direct protein-protein interaction of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen. Biochimica et biophysica acta. Molecular cell research, Vol. 1783, Issue 8. pp. 1536-1543.

2007

Nashev, L. G. and Chandsawangbhuwana, C. and Balazs, Z. and Atanasov, A. G. and Dick, B. and Frey, F. J. and Baker, M. E. and Odermatt, A.. (2007) Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. PLoS ONE, Vol. 2, H. 6 , e561.

Atanasov, A. G. and Ignatova, I. D. and Nashev, L. G. and Dick, B. and Ferrari, P. and Frey, F. J. and Odermatt, A.. (2007) Impaired protein stability of 11beta-hydroxysteroid dehydrogenase type : a novel mechanism of apparent mineralocorticoid excess. Journal of the American Society of Nephrology, Vol. 18, H. 4. pp. 1262-1270.