Items where contributor is "Harms, Alexander"

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Maffei, Enea and Burkolter, Marco and Heyer, Yannik and Egli, Adrian and Jenal, Urs and Harms, Alexander. (2022) Phage Paride hijacks bacterial stress responses to kill dormant, antibiotic-tolerant cells. bioRxiv. p. 477855.

Shaidullina, Aisylu and Harms, Alexander. (2022) Antiviral death punch by ADP-ribosylating bacterial toxins. Trends in Microbiology, 30 (10). pp. 920-921.

Maffei, Enea and Fino, Cinzia and Harms, Alexander. (2021) Antibiotic Tolerance and Persistence Studied Throughout Bacterial Growth Phases. In: Bacterial Persistence, 2357. Cham, pp. 23-40.

Reinders, Alberto and Sellner, Benjamin and Fadel, Firas and van Berkum, Margo and Kaczmarczyk, Andreas and Ozaki, Shogo and Rueher, Johanna and Manfredi, Pablo and Sangermani, Matteo and Harms, Alexander and Perez, Camilo and Schirmer, Tilman and Jenal, Urs. (2021) Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity.

Maffei, Enea and Harms, Alexander. (2021) Messages from the dead protect bacteria from viral attack. The EMBO Journal, 41 (3). e110382.

Harms, Alexander and Diard, Médéric. (2019) Crowd Controlled-Host Quorum Sensing Drives Phage Decision. Cell host & microbe, 25 (2). pp. 179-181.

Harms, Alexander. (2019) The Biology of Persister Cells in Escherichia coli. In: Persister Cells and Infectious Disease. Cham, pp. 39-57.

Harms, A. and Gerdes, K.. (2016) Back to the Roots: Deep View into the Evolutionary History of ADP-Ribosylation Opened by the DNA-Targeting Toxin-Antitoxin Module DarTG. Molecular cell, 64 (6). pp. 1020-1021.


Shaidullina, Aisylu and Harms, Alexander. (2022) Toothpicks, logic, and next-generation sequencing: systematic investigation of bacteriophage-host interactions. Current Opinion in Microbiology, 70. p. 102225.

Dietz, Nikolaus and Huber, Markus and Sorg, Isabel and Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2021) Structural basis for selective AMPylation of Rac-subfamily GTPases by Bartonella effector protein 1 (Bep1). Proceedings of the National Academy of Sciences, 118 (12). e2023245118.

Schirmer, Tilman and de Beer, Tjaart A. P. and Tamegger, Stefanie and Harms, Alexander and Dietz, Nikolaus and Dranow, David M. and Edwards, Thomas E. and Myler, Peter J. and Phan, Isabelle and Dehio, Christoph. (2021) Evolutionary Diversification of Host-Targeted; Bartonella; Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9 (8). p. 23.

Maffei, Enea and Shaidullina, Aisylu and Burkolter, Marco and Heyer, Yannik and Estermann, Fabienne and Druelle, Valentin and Sauer, Patrick and Willi, Luc and Michaelis, Sarah and Hilbi, Hubert and Thaler, David Solomon and Harms, Alexander. (2021) Systematic exploration of Escherichia coli phage-host interactions with the BASEL phage collection. PLoS Biology, 19 (11). e300142.

Sorg, Isabel and Schmutz, Christoph and Lu, Yun-Yueh and Fromm, Katja and Siewert, Lena K. and Bögli, Alexandra and Strack, Kathrin and Harms, Alexander and Dehio, Christoph. (2020) A Bartonella effector acts as signaling hub for intrinsic STAT3 activation to trigger anti-inflammatory responses. Cell host & microbe, 27 (3). pp. 476-485.

Horesh, Gal and Fino, Cinzia and Harms, Alexander and Dorman, Matthew J. and Parts, Leopold and Gerdes, Kenn and Heinz, Eva and Thomson, Nicholas R.. (2020) Type II and type IV toxin-antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population. Nucleic Acids Research, 48 (8). pp. 4357-4370.

Fino, Cinzia and Vestergaard, Martin and Ingmer, Hanne and Pierrel, Fabien and Gerdes, Kenn and Harms, Alexander. (2020) PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10. MicrobiologyOpen, 9 (8). e1064.

Balaban, Nathalie Q. and Helaine, Sophie and Lewis, Kim and Ackermann, Martin and Aldridge, Bree and Andersson, Dan I. and Brynildsen, Mark P. and Bumann, Dirk and Camilli, Andrew and Collins, James J. and Dehio, Christoph and Fortune, Sarah M. and Ghigo, Jean-Marc and Hardt, Wolf-Dietrich and Harms, Alexander and Heinemann, Matthias and Hung, Deborah T. and Jenal, Urs and Levin, Bruce R. and Michiels, Jan and Storz, Gisela and Tan, Man-Wah and Tenson, Tanel and Van Melderen, Laurence and Zinkernagel, Annelies. (2019) Definitions and guidelines for research on antibiotic persistence. Nature Reviews Microbiology, 17 (7). pp. 441-448.

Svenningsen, Mikkel Skjoldan and Veress, Alexandra and Harms, Alexander and Mitarai, Namiko and Semsey, Szabolcs. (2019) Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells. Scientific Reports, 9 (1). p. 6056.

Harms, A. and Brodersen, D. E. and Mitarai, N. and Gerdes, K.. (2018) Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology. Molecular cell, 70 (5). pp. 768-784.

Horesh, G. and Harms, A. and Fino, C. and Parts, L. and Gerdes, K. and Heinz, E. and Thomson, N. R.. (2018) SLING: a tool to search for linked genes in bacterial datasets. Nucleic Acids Res, 46 (21). e128.

Harms, Alexander and Fino, Cinzia and Sørensen, Michael A. and Semsey, Szabolcs and Gerdes, Kenn. (2017) Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells. MBio, 8 (6). ii:e01964-17.

Stanger, Frédéric V. and Burmann, Björn M. and Harms, Alexander and Aragão, Hugo and Mazur, Adam and Sharpe, Timothy and Dehio, Christoph and Hiller, Sebastian and Schirmer, Tilman. (2016) Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proceedings of the National Academy of Sciences of the United States of America, 113 (5). E529-E537.

Stanger, Frédéric V. and Harms, Alexander and Dehio, Christoph and Schirmer, Tilman. (2016) Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin. PLoS ONE, 11 (9). e0163654.

Harms, Alexander and Stanger, Frédéric Valentin and Dehio, Christoph. (2016) Biological Diversity and Molecular Plasticity of FIC Domain Proteins. Annual Reviews of Microbiology, 70. pp. 341-360.

Harms, A. and Maisonneuve, E. and Gerdes, K.. (2016) Mechanisms of bacterial persistence during stress and antibiotic exposure. Science, 354 (6318). ii:aaf4268.

Harms, Alexander and Stanger, Frédéric Valentin and Scheu, Patrick Daniel and de Jong, Imke Greet and Goepfert, Arnaud and Glatter, Timo and Gerdes, Kenn and Schirmer, Tilman and Dehio, Christoph. (2015) Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology. Cell Reports, 12 (9). pp. 1497-1507.

Pieles, Kathrin and Glatter, Timo and Harms, Alexander and Schmidt, Alexander and Dehio, Christoph. (2014) An experimental strategy for the identification of AMPylation targets from complex protein samples. Proteomics, 14 (9). pp. 1048-1052.

Goepfert, Arnaud and Harms, Alexander and Schirmer, Tilman and Dehio, Christoph. (2013) Type II Toxin-Antitoxin Loci: The fic Family. In: Prokaryotic Toxin-Antitoxins. Heidelberg, pp. 177-187.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the Radar : Molecular Pathogenesis of Bartonella spp. Clinical microbiology reviews, Vol. 25, H. 1. pp. 42-78.

Engel, Philipp and Goepfert, Arnaud and Stanger, Frédéric V. and Harms, Alexander and Schmidt, Alexander and Schirmer, Tilman and Dehio, Christoph. (2012) Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins. Nature, 482 (7383). pp. 107-110.

Harms, Alexander and Dehio, Christoph. (2012) Intruders below the radar: molecular pathogenesis of Bartonella spp. Clinical microbiology reviews, 25 (1). pp. 42-78.