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Items where contributor is "Häberli, Cécile"

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2022

Angeli, A. and Ferraroni, M. and Carta, F. and Häberli, C. and Keiser, J. and Costantino, G. and Supuran, C. T.. (2022) Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37 (1). pp. 1479-1494.

Biendl, S. and Häberli, C. and Keiser, J.. (2022) Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box. Expert Rev Anti Infect Ther, 20 (4). pp. 621-629.

Cantara, A. and Luo, Y. and Dobrovolna, M. and Bohalova, N. and Fojta, M. and Verga, D. and Guittat, L. and Cucchiarini, A. and Savrimoutou, S. and Häberli, C. and Guillon, J. and Keiser, J. and Brazda, V. and Mergny, J. L.. (2022) G-quadruplexes in helminth parasites. Nucleic Acids Res, 50 (5). pp. 2719-2735.

Di Bello, E. and Noce, B. and Fioravanti, R. and Zwergel, C. and Valente, S. and Rotili, D. and Fianco, G. and Trisciuoglio, D. and Mourão, M. M. and Sales, P. and Jr., and Lamotte, S. and Prina, E. and Späth, G. F. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni. ACS Infect Dis, 8 (7). pp. 1356-1366.

Dube, M. and Llanes, D. and Saoud, M. and Rennert, R. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2022) Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: natural fungal compounds and synthetic derivatives with in vitro anthelmintic activities and antiproliferative effects against two human cancer cell lines. Molecules, 27 (9). p. 2950.

Dube, M. and Raphane, B. and Sethebe, B. and Seputhe, N. and Tiroyakgosi, T. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N. and Andrae-Marobela, K.. (2022) Medicinal plant preparations administered by botswana traditional health practitioners for treatment of worm infections show anthelmintic activities. Plants (Basel), 11 (21). p. 2945.

Harrington, S. and Knox, J. J. and Burns, A. R. and Choo, K. L. and Au, A. and Kitner, M. and Haeberli, C. and Pyche, J. and D'Amata, C. and Kim, Y. H. and Volpatti, J. R. and Guiliani, M. and Snider, J. and Wong, V. and Palmeira, B. M. and Redman, E. M. and Vaidya, A. S. and Gilleard, J. S. and Stagljar, I. and Cutler, S. R. and Kulke, D. and Dowling, J. J. and Yip, C. M. and Keiser, J. and Zasada, I. and Lautens, M. and Roy, P. J.. (2022) Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release. Commun Biol, 5. p. 865.

Hassan, M. M. and Sedighi, A. and Olaoye, O. O. and Haberli, C. and Merz, A. and Ramos-Morales, E. and de Araujo, E. D. and Romier, C. and Jung, M. and Keiser, J. and Gunning, P. T.. (2022) Phenotypic screening of histone deacetylase (HDAC) inhibitors against Schistosoma mansoni. ChemMedChem. e202100622.

Kersting, L. and Kuhn, L. and Anokhin, M. and Schuster, F. and Häberli, C. and Sambyal, S. and Kumar, H. M. S. and Keiser, J. and Alabugin, I. and Tsogoeva, S. B.. (2022) Visible-light-driven metal-free C-H functionalization: access to new bioactive tetrahydroisoquinoline-butenolide hybrids via domino amine oxidation/vinylogous mannich reaction. ChemPhotoChem, 6 (8). e202200109.

Ren, R. and Wang, X. and Leas, D. A. and Häberli, C. and Cal, M. and Dong, Y. and Kaiser, M. and Keiser, J. and Vennerstrom, J. L.. (2022) Antischistosomal tetrahydro-γ-carboline sulfonamides. Bioorganic & medicinal chemistry letters, 59. p. 128546.

Schneeberger, P. H. H. and Gueuning, M. and Welsche, S. and Hürlimann, E. and Dommann, J. and Haberli, C. and Frey, J. E. and Sayasone, S. and Keiser, J.. (2022) Different gut microbial communities correlate with efficacy of albendazole-ivermectin against soil-transmitted helminthiases. Nat Commun, 13. p. 1063.

Taki, A. C. and Wang, T. and Nguyen, N. N. and Ang, C. S. and Leeming, M. G. and Nie, S. and Byrne, J. J. and Young, N. D. and Zheng, Y. and Ma, G. and Korhonen, P. K. and Koehler, A. V. and Williamson, N. A. and Hofmann, A. and Chang, B. C. H. and Haberli, C. and Keiser, J. and Jabbar, A. and Sleebs, B. E. and Gasser, R. B.. (2022) Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868. Front Pharmacol, 13. p. 1014804.

Noce, B. and Di Bello, E. and Zwergel, C. and Fioravanti, R. and Valente, S. and Rotili, D. and Masotti, A. and Ansari, M. S. Z. and Trisciuoglio, D. and Chakrabarti, A. and Romier, C. and Robaa, D. and Sippl, W. and Jung, M. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages. ChemMedChem. In press.

Valderas-García, E. and Häberli, C. and Álvarez-Bardón, M. and Escala, N. and Castilla-Gómez de Agüero, V. and de la Vega, J. and Del Olmo, E. and Balaña-Fouce, R. and Keiser, J. and Martínez-Valladares, M.. (2022) Benzimidazole and aminoalcohol derivatives show in vitro anthelmintic activity against Trichuris muris and Heligmosomoides polygyrus. Parasit Vectors, 15. p. 243.

Hamway, Y. and Zimmermann, K. and Blommers, M. J. J. and Sousa, M. and Häberli, C. and Kulkarni, S. and Skalicky, S. and Hackl, M. and Götte, M. and Keiser, J. and da Costa, C. P. and Spangenberg, T. and Azzaoui, K.. (2022) Modulation of host-parasite interactions with small molecules targeting Schistosoma mansoni microRNAs. ACS Infect Dis, 8. 2028−2034.

2021

Buchter, V. and Hofmann, D. and Häberli, C. and Keiser, J.. (2021) Characterization of moxidectin against; Strongyloides ratti:; in vitro; and; in vivo; activity and pharmacokinetics in the rat model. ACS Infect Dis, 7 (5). pp. 1069-1076.

Dube, M. and Saoud, M. and Rennert, R. and Fotso, G. W. and Andrae-Marobela, K. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2021) Anthelmintic activity and cytotoxic effects of compounds isolated from the fruits of Ozoroa insignis del. (Anacardiaceae). Biomolecules, 11 (12). p. 1893.

Debbert, S. L. and Hintz, M. J. and Bell, C. J. and Earl, K. R. and Forsythe, G. E. and Häberli, C. and Keiser, J.. (2021) Activities of quinoxaline, nitroquinoxaline and [1,2,4]triazolo[4,3-a]quinoxaline analogs of MMV007204 against; Schistosoma mansoni. Antimicrobial agents and chemotherapy, 65 (3). e01370-20.

Keiser, J. and Häberli, C.. (2021) Assessment of FDA-approved drugs against Strongyloides ratti in vitro and in vivo to identify potentially active drugs against strongyloidiasis. Parasit Vectors, 14. p. 615.

Keiser, J. and Häberli, C.. (2021) Evaluation of commercially available anthelminthics in laboratory models of human intestinal nematode infections. ACS Infect Dis, 7 (5). pp. 1177-1185.

Probst, A. and Pujol, E. and Häberli, C. and Keiser, J. and Vázquez, S.. (2021) In vitro, in vivo, and ADME evaluation of SF5-containing N,N'-diarylureas as antischistosomal agents. Antimicrobial agents and chemotherapy, 65 (10). e0061521.

Probst, A. and Chisanga, K. and Dziwornu, G. A. and Häberli, C. and Keiser, J. and Chibale, K.. (2021) Expanding the activity profile of pyrido[1,2-a]benzimidazoles: synthesis and evaluation of novel n(1)-1-phenylethanamine derivatives against Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1032-1043.

Partridge, F. A. and Bataille, C. J. R. and Forman, R. and Marriott, A. E. and Forde-Thomas, J. and Häberli, C. and Dinsdale, R. L. and O'Sullivan, J. D. B. and Willis, N. J. and Wynne, G. M. and Whiteland, H. and Archer, J. and Steven, A. and Keiser, J. and Turner, J. D. and Hoffmann, K. F. and Taylor, M. J. and Else, K. J. and Russell, A. J. and Sattelle, D. B.. (2021) Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1260-1274.

Nguyen, W. and Lee, E. F. and Evangelista, M. and Lee, M. and Harris, T. J. and Colman, P. M. and Smith, N. A. and Williams, L. B. and Jarman, K. E. and Lowes, K. N. and Häberli, C. and Keiser, J. and Smith, B. J. and Fairlie, W. D. and Sleebs, B. E.. (2021) Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a. ACS Infect Dis, 7 (5). pp. 1143-1163.

Sirak, B. and Asres, K. and Hailu, A. and Dube, M. and Arnold, N. and Häberli, C. and Keiser, J. and Imming, P.. (2021) In vitro antileishmanial and antischistosomal activities of anemonin isolated from the fresh leaves of Ranunculus multifidus forsk. Molecules, 26 (24). p. 7473.

2020

Wu, Jianbo and Wang, Xiaofang and Chiu, Francis C. K. and Häberli, Cécile and Shackleford, David M. and Ryan, Eileen and Kamaraj, Sriraghavan and Bulbule, Vivek J. and Wallick, Alexander I. and Dong, Yuxiang and White, Karen L. and Davis, Paul H. and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2020) Structure-activity relationship of antischistosomal ozonide carboxylic acids. Journal of medicinal chemistry, 63 (7). pp. 3723-3736.

Lin, Yan and Ong, Yih Ching and Keller, Sarah and Karges, Johannes and Bouchene, Rafika and Manoury, Eric and Blacque, Olivier and Müller, Joachim and Anghel, Nicoleta and Hemphill, Andrew and Häberli, Cécile and Taki, Aya C. and Gasser, Robin B. and Cariou, Kevin and Keiser, Jennifer and Gasser, Gilles. (2020) Synthesis, characterization and antiparasitic activity of organometallic derivatives of the anthelmintic drug albendazole. Dalton Transactions, 49 (20). pp. 6616-6626.

Probst, Alexandra and Häberli, Cécile and Siegel, Dionicio and Huang, Jianbo and Vigneron, Seth and Ta, Anh P. and Skinner, Danielle E. and El-Sakkary, Nelly and Momper, Jeremiah D. and Gangoiti, Jon and Dong, Yuxiang and Vennerstrom, Jonathan L. and Charman, Susan A. and Caffrey, Conor R. and Keiser, Jennifer. (2020) Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone. The journal of antimicrobial chemotherapy. dkaa247.

2019

Mayoka, Godfrey and Keiser, Jennifer and Häberli, Cécile and Chibale, Kelly. (2019) Structure-activity relationship and in vitro absorption, distribution, metabolism, excretion, and toxicity (ADMET) studies of N-aryl 3-trifluoromethyl pyrido[1,2-a]benzimidazoles that are efficacious in a mouse model of Schistosomiasis. ACS infectious diseases, 5 (3). pp. 418-429.

Karpstein, Tanja and Pasche, Valérian and Häberli, Cécile and Scandale, Ivan and Neodo, Anna and Keiser, Jennifer. (2019) Evaluation of emodepside in laboratory models of human intestinal nematode and schistosome infections. Parasites and Vectors, 12. p. 226.

2018

Wu, Jianbo and Wang, Chunkai and Häberli, Cécile and White, Karen L. and Shackleford, David M. and Chen, Gong and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2018) SAR of a new antischistosomal urea carboxylic acid. Bioorganic & medicinal chemistry letters, 28 (23-24). pp. 3648-3651.