Browse by Basel Advisors

Abegg, Vanessa Fabienne. Safety assessment of herbal drugs as alternatives to treat non-psychotic mental diseases during pregnancy. 2024, Doctoral Thesis, University of Basel, Faculty of Science.

Bolten, Jan Stephan. The study of renal function and toxicity using zebrafish (Danio rerio) larvae as a vertebrate model. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Jäger, Marie-Christin. Pharmaceutical-induced disturbances of adrenal steroidogenesis with a focus on pseudohyperaldosteronism: Identification and characterization of potentially hazardous drugs. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Grötsch, Anna Deborah. Investigating the role of hexose-6-phosphate dehydrogenase in mouse metabolism and muscle function. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Hauswirth, Patrick. Design and delivery of genes encoding oncotoxic proteins for cancer therapy. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Bachmann, Fabio. Metabolism and Drug-Drug Interaction Studies of Metamizole in Humans. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Buck, Jonas. Strategies to Improve Non-Viral Gene Delivery and the Preclinical Investigation of Nanomedicines. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Weingartner, Michael. Towards the Understanding of the Molecular and Physiological Role of Hexose-6-Phosphate Dehydrogenase. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Dreckmann, Tim. Low Volume Aseptic Filling of Monoclonal Antibodies. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Schreiner, Viktoria. Design, Characterization and In Vivo Evaluation of a Microparticulate Depot Formulation of Buprenorphine for Veterinary Use. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Meyer, Claire. Catalytic bio-hybrid polymersomes: towards novel biomedical applications. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Schuster, Joachim. Development of In Vitro Models and Analytical Methods to Assess the In Vivo Stability of Therapeutic Proteins. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Roos, Noëmi Johanna. Role of the NRF2-mediated oxidative stress response and lysosomal dysfunction in drug-induced liver injury associated with mitochondrial damage. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Kullmann, Daniel. Aseptically safe and fast administration of freeze-dried drug products: application for emergency cases and tropical diseases. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Vizeli, Patrick Raphael. Safety pharmacology and pharmacogenetics of 3,4-methylenedioxymethamphetamine (MDMA). 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Zhou, Xun. Molecular toxicological mechanisms of new psychoactive substances "in vitro". 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Çörek, Emre. Superparamagnetic iron oxide nanoparticles for imaging and drug delivery. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Farzan, Maryam. Porous Functionalized Calcium Carbonate Microparticle as a Drug Carrier: Pore-scale structure and its role in drug delivery. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Roth, Roger. Functionalized calcium carbonate based peptide formulation : aspects of the development for oral delivery to the buccal and intestinal mucosa. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Rudin, Deborah. Toxicological and clinical investigations of metamizole-associated neutropenia. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Patt, Melanie. Xenobiotics interfering with corticosteroid action : from adrenal steroid synthesis to peripheral receptor activity. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Häuser, Christina. Investigation of lyophilized antibody formulations to enable short freeze-drying cycles and storage at room temperature. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Schittny, Andreas. Amorphous solid dispersions as oral delivery system for poorly soluble drugs – mechanistic and translational research. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Burgio, Floriana. Modulation of gold nanoparticle surface chemistry to target glioblastoma cells for SERS based imaging. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Marbet, Philippe. Implementation of primary cells for mechanistic investigations of inflammatory and metabolic diseases. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Jetzer, Martin. Particle interactions in complex dry powder inhaled formulations and single particle aerosol mass spectrometry. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Sieber, Sandro. The zebrafish: a preclinical screening model for the optimization of nanomedicine formulations. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Kiene, Klara. Towards the next generation of drug administration: evaluation of drug delivery systems in vitro, in vivo, and in clinical settings. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Matviykiv, Sofiya. Preparation and characterization of nanometer-sized mechano-responsive liposomes for physically-triggered drug delivery. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Hösli, Raphael. Advances in therapeutic drug monitoring with a focus on phenytoin analysis. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Grünig, David Alexander. Molecular mechanisms of drug-induced hepatic steatosis. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Grossen, Philip. Nanomedicines in cancer therapy : from long-circulating drug carriers to novel therapeutic concepts. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Einfalt, Tomaž. Biomimetic engineering of colloidal nanoarchitectures with "in vitro" and "in vivo" functionality. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Wagner-Hattler, Leonie. Oral formulations for children : the microstructure of functionalized calcium carbonate as key characteristic to develop age-appropriate and compliance enhanced formulations. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Siegrist, Stefan Kevin. Assessing the safety of engineered nanoparticles designed for therapeutic use. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Steinl, David. Contrast enhanced ultrasound molecular imaging of the inflammatory response in myocarditis. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Rickli, Anna. Pharmacology of novel psychoactive substances. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Bui, Duy Anh. Light-emitting diodes and photodiodes in the deep ultra-violet range for absorption photometry in liquid chromatography, capillary electrophoresis and gas sensing. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Witzigmann, Dominik. Hepatocyte-specific drug delivery using active targeted nanomedicines - evaluation of targeting strategies in vitro and in vivo. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Mancuso, Riccardo. Identification and characterization of novel αLβ2 inhibitors and their differentiation from known inhibitors. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Camblin, Marine. Use of particulate material for the formulation of diagnostic products. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Vranic, Branko Z.. Design of experiments methodology in studying near-infrared spectral information of model intact tablets : simultaneous determination of metoprolol tartrate and hydrochlorothiazide in solid dosage forms and powder compressibility assessment using near-infrared spectroscopy. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Donzelli, Massimiliano. Development, validation and application of the Basel phenotyping cocktail. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Hägler, Patrizia. Establishment of "in vitro" and "in vivo" models with underlying mitochondrial dysfunction for testing idiosyncratic drug toxicity. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Folzer, Emilien. Techniques for fractionation, isolation and characterization of subvisible and submicron particles in biopharmaceutical preparations. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Sohn, Myriam. In vitro biorelevant and in silico sunscreen performance evaluation on the basis of film Thickness frequency distribution of formulations and UV filter repartition. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Eberle, Veronika Anna. Floating gastroretentive drug delivery systems based on functionalized calcium carbonate. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Preisig, Daniel. Development of a mucoadhesive and multiparticulate colon drug delivery system. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Ríos Quiroz, Anacelia. Application of novel techniques for characterization of subvisible and sub-micron particles in biopharmaceutical preparations. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Benischke, Anne-Sophie. Ubiquitin-proteasome dependent mitochondrial protein quality control. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Felser, Andrea Debora. Mechanisms of hepatocellular toxicity associated with dronedarone and other mitochondrial toxicants. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Dieu, Le-Ha. "In vitro" evaluation of blood-brain barrier transport. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Allmendinger, Andrea Martina. Rheological investigation of manufacturability and injectability of highly concentrated monoclonal antibody formulations. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Kunze, Annett. Prediction of human drug clearance and anticipation of clinical drug-drug interaction potential from in vitro drug transport studies. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Stirnimann, Tanja. Characterization of functionalized calcium carbonate as a new pharmaceutical excipient. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Stillhart, Cordula Edith. Insights into the biopharmaceutical behavior of oral lipid-based formulations using advanced analytical techniques and mathematical modeling. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Kettiger, Hélène Emilie. Silica nanoparticles and their interaction with cells : a multidisciplinary approach. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Detampel, Pascal. Targeting of hepatocytes using vector-conjugated liposomes : evaluation of targeting strategies. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Khanicheh, Elham. Cardiovascular molecular imaging. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Martínez Heredia, Lizbeth Araceli. Batch and continuous blending of particulate material studied by near-infrared spectroscopy. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Simmler, Linda. Pharmacology of amphetamine-type designer drugs. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Duthaler, Urs Philipp. Artemisinins for the treatment of fascioliasis : progress in preclinical and diagnostic research. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Bourqui, Réjane Morand. Carnitine : analytical and physiological aspects. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Müller, Christian Thomas Benedikt. The interaction of amyloid-β peptide with lipid membranes and glycosaminoglycans. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Kwan, Hiu Ying. Enantioselective capillary electrophoresis : fundamental aspects and application to the "in vitro" assessment of CYP3A4 mediated ketamine N-demethylation. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Zehender, Fabian. Biophysical characterization of reactions associated with reverse cholesterol transport. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Mullen, Peter James. Molecular mechanisms of statin-induced myotoxicity. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Suenderhauf, Claudia. "In silico" prediction of drug transport across physiological barriers. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Smieskova, Renata. Brain structural and neurofunctional correlates of liability to psychosis : a multimodal neuroimaging approach. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Poller, Birk. Evaluation of the hCMEC/D3 cell line, a new "in vitro" model of the human blood-brain barrier for transport and gene regulation studies. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Maier, Angelika Erika. Transcriptional regulation and impact of ABC-transporters in intestinal cell lines. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Hammann, Felix. Prediction of transport, pharmacokinetics, and effect of drugs. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Grauwiler, Sandra Béatrice. Development and application of a LC-MS/MS method for the analysis of plasma bioavailabilities of different cannabinoids after the administration of "Cannabis sativa L." extracts and MarinolTM. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Yam, Jianying. The search for bioactive compounds in tropical plants to target hormone imbalance associated diseases. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Äänismaa, Päivi. Thermodynamics and kinetics of P-glycoprotein-substrate interactions. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Hruz, Petr. Expression and regulation of transmembrane transporters in healthy intestine and gastrointestinal diseases. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Kusch-Poddar, Manisha. "In vitro" models of the blood-brain barrier : applications and evaluation of a new human immortalized brain capillary endothelial cell line. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Schlatter, Philipp. Characterisation and validation of drug transport and GLP-1R function in primary porcine proximal tubular cells. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Schnyder, Anita. "In vitro" and "in vivo" drug targeting using biotinylated immunoliposomes. 2005, Doctoral Thesis, University of Basel, Faculty of Science.