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Browse by Basel Advisors

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Doctoral Thesis

Paradiso, Viola. Genetic screening and molecular characterisation of biomarkers in hepatocellular carcinoma. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Gao, Ruize. Molecular mechanisms of therapy resistance in HCC: USP29-mediated HIF1a stabilization promotes Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis and YAP/TAZ and ATF4 collaboratively drive resistance to Sorafenib therapy in hepatocellular carcinoma by preventing ferroptosis. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Keles, Erhan. Novel PI3K and mTOR selective inhibitors to deconvolute PI3K signaling. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Rohm, Theresa. Targeting colonic macrophages as a potential therapeutic option in metabolic disease. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Bianco, Gaia. Deregulation of embryonic transcription factors in human epithelial cancers: new perspectives in breast and liver tumors. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Scheidmann, Manuel Christopher. In Vivo Identification of Genetic Requirements for the Generation and Colonization of Circulating Tumor Cells. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Zilli, Federica. Unbiased Piggybac Mutagenesis Screens Identify Tumorigenic and Metastatic Pathways in Breast Cancer. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Büchel, David Martin. Wnt/β-catenin signaling in malignant mammary tumor progression and metastasis formation & Mechanisms of evasive resistance to sorafenib in hepatocellular carcinoma. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Szczerba, Barbara. Single-cell resolution characterization of circulating tumor cell clusters. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Tiede, Stefanie Nicole. Tumour heterogeneity during the progression of metastatic breast cancer and anti-tumour effects of the novel FAK inhibitor BI 853520 in breast cancer. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Lüönd, Fabiana Maria. The contribution of partial and full epithelial-to-mesenchymal transition to breast cancer progression. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Donato, Cinzia. Intra-tumor hypoxia drives the formation of breast cancer circulating tumor cell clusters. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Blumer, Tanja. Negative regulation of interferon lambda induced JAK-STAT signaling and development of patient-derived xenograft models from fresh human hepatocellular carcinoma biopsies. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Bovo, Emmanuela. Mechanisms of vascular stabilization by PDGF-BB. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Manfredonia, Celeste. Maintenance of primary human colorectal cancer microenvironment using a perfusion bioreactor-based 3D culture system. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Alam, Md. Shahidul. Dissecting the molecular function of neutral glycosphingolipids in ovarian cancer progression. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Kilinc, Ayse Nihan. Epigenetic mechanisms regulating epithelial-mesenchymal plasticity in breast cancer. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Prêtre, Vincent. From the regulatory role of PDPN in mTOR/PI3K/Akt signaling to clinical trials. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Ronen, Dana Ishay. From cancer cell plasticity to differentiation therapy. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Avramović, Dragana. Targeting angiogenesis with small antibody fragments and antibody-like molecules. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Gürbüz, Irem. Discovery of novel MKL1 target genes important for cancer progression and metastasis : a focus on WNT1 inducible signaling pathway protein 1 (WISP1/CCN4). 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Frei, Anna. Studies on the role of two proteins in breast cancer - histone deacetylase 11 in estrogen receptor positive breast cancer and the redox protein memo in metastasis and tumorigenesis. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Diepenbruck, Maren. Transcriptional and post-transcriptional mechanisms regulating epithelial to mesenchymal transition in breast cancer. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Dimitrova, Yoana. Robustness and plasticity of epithelial cell state in development and malignancy. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Martin, Katrin. Growth-factor-induced, persistent fibroblast migration is mediated by mechanical insulation of cell front and back. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Muraro, Manuele Giuseppe. Functional validation of cancer stem cell markers in primary human colorectal cancer and established cell lines. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Schneider, Ralph Philipp. The TRF1 telomere protein is essential for the generation and maintenance of iPS cells and marks both pluripotent and adult stem cells. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Scharenberg, Matthias. Identification and characterization of two isoforms of human megakaryoblastic Leukemia-1 and their specific regulation in myofibroblast differentiation. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Feltrin, Daniel. Local mRNA translation in the regulation of neurite outgrowth. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Waldmeier, Lorenz. Epithelial to mesenchymal transition in breast cancer : a novel murine model system and the regulatory role of tead transcription factors. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Aceto, Nicola. Opposing roles for protein tyrosine phosphatases SHP2 and PTPN12 in breast cancer. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Tiwari, Neha. Transcriptional control of epithelial to mesenchymal transition by regulatory factors and epigenetic mechanisms. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Dey, Julien Hervé. Investigating the contribution of FGF receptors in breast tumorigenesis using models of mammary cancer. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Rajski, Michal. Tumor-stroma derived gene expression patterns as prognosticators in breast cancer. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Matsuda, Yutaka. Dissecting the roles of WNT signaling in breast cancer using "in vitro" and "in vivo" experimental models. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Zumsteg, Adrian. The contribution of bone marrow-derived cells to angiogenesis and lymphangiogenesis in murine models of carcinogenesis. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Baeriswyl, Vanessa. Tumor-induced myeloid cell plasticity toward lymphatic endothelium. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Heinrich, Constanze Katharina. Copine III interacts with ERBB2 and promotes tumor cell migration. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Yilmaz, Mahmut. The role of the cell adhesion molecule NCAM and the transcription factor Dlx2 in epithelial-mesenchymal transition (EMT) and tumor progression. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Zhang, Jian. Identification of novel germline mutations in hereditary colorectal cancer patients and characterization of somatic alterations in their tumors. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Jia, Yundan. In vivo analysis of the role of tenascin-C in tumorigenesis. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Jäggi, Fabienne. The role of Sprouty4 in development and cancer and functional consequences of Sprouty interacting with Caveolin-1. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Kren, Angelika. The role of NCAM signaling and its effector protein, [beta]1-integrin, in tumor progression. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Wicki, Andreas Christian. Cancer - from mechanisms of invasion to targeted therapy. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Ghosh, Sourabh. Role of tumor architecture in elicitation of effector functions of human cytotoxic T-lymphocytes recognizing melanoma associated antigens. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Grotegut, Stefan. The role of hepatocyte growth factor/scatter factor in hepatoblastoma and hepatocellular carcinoma progression. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Kopfstein, Lucie. VEGF family members : modulators of tumor angiogenesis and lymphangiogenesis. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Li, Weimin. Responses to hypoxia via mTOR : role in endothelial cell proliferation and HIF-1[alpha] stabilization. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Kleiner, Sandra. Isoform-specific roles of the adaptor protein ShcA in cell signaling. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Cicenas, Jonas. ErbB2 signaling in breast cancer : the role of ErbB, Akt and ShcA phosphorylation. 2004, Doctoral Thesis, University of Basel, Faculty of Science.