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Browse by Basel Advisors

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Schürch, Christoph. SRP54 mutations induce Congenital Neutropenia via dominant-negative effects on XBP1 splicing. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Hanns, Pauline. Study of variables determining the engraftment and homing of human acute myeloid leukemia samples in the NSG mouse model. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Dönges, Laura. Modelling and targeting osteoarthritis using human progenitor cell-derived cartilage organoids. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Kalita, Joanna Małgorzata. Auxiliary barrier function of karyopherins at the Nuclear Pore Complex. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Blumer, Sabrina. Deciphering the role of fibrosis-specific alveolar basal cells in idiopathic pulmonary fibrosis. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Zhang, Yuepeng. Location, dynamics and expression of functional proteins in the HIV viral reservoir. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Heutschi, Daniel. Genetic analysis of genes linked to lumen formation in the zebrafish vasculature. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Malkmus, Jonas. Cis-Regulation of Gremlin1 Expression during Mouse Limb Bud Development and its Diversification during Vertebrate Evolution. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

D'Otolo, Viviana. Functional complementarity of mammalian coronins determines T cell population homeostasis. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Gordian, Born. Perfusion culture systems to engineer 3D biomimetic bone marrow tissues. 2022, Doctoral Thesis, University of Basel, Faculty of Medicine.

Singh, Shubham. Toolset for incorporation of unnatural amino acids into proteins expressed in mammalian cells. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Rouchon, Adelin. VEGF decoration of fibrin scaffolds for in vitro and in vivo engineering of vascularized tissues. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Simon, Niklas. Dpp dispersal in the Drosophila melanogaster wing disc. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Lee, Minkyoung. Genetic Analysis of Blood Vessel Morphogenesis: the role of Rasip1 in the regulation of junctional dynamics during angiogenic sprouting and lumen formation. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Grosso, Andrea. Vascular Endothelial Growth Factor (VEGF) and Semaphorin 3A (Sema3A) signaling for vascularized bone grafts. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Brown, Jennifer Anne. Towards 95% Viral Suppression: Targeting HIV Drug Resistance, Adherence to Therapy, and Access to Care in Southern and East Africa. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Ramos Martins, Laurène. The Gremlin1 cis-regulatory landscape: a paradigm to study enhancer cooperation in regulation of transcription dynamics. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Wiesner, Cora. Analysis of junctional and F-actin dynamics during blood vessel morphogenesis. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Girdžiušaitė, Aušra. TBX3 and HAND2 Controlled Gene Regulatory Networks in Establishment of Axis Polarity in Mouse Limb Buds. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Coomar, Seemon. Investigations around RBM39 degrading arylsulfonamides. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Schmelzer, Etienne. Endo-lysosomal dynamics during transcellular lumen formation in the vasculature. Analysis of the dynamics of late endosomal, lysosomal compartments during transcellular lumen formation by high spatial and temporal resolution microscopy. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Tissières, Virginie. Dissection of Ptch1 cis-regulatory robustness in the context of artiodactyl limb evolution. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Haumer, Alexander. Prefabrication of vascularized large bone grafts. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Bovo, Emmanuela. Mechanisms of vascular stabilization by PDGF-BB. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Paczulla, Anna Maria. Investigation of mechanisms regulating leukemogenesis using mouse xenograft models of human acute myeloid leukemia. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Schellinx, Niels. Deciphering cytoskeletal junctional interactions during blood vessel morphogenesis in vivo : introduction of novel genetic tools for mosaic analysis of Cdh5/VE-cadherin regulation and function & phenotypic analysis of RadilB function in sprouting angiogenesis. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Nuciforo, Sandro. Liver cancer in a dish: modelling hepatocellular carcinoma using patient-derived tumor organoids. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Saito, Makoto. Acetylation of intrinsically disordered regions regulates liquid-liquid phase separation. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Sieber, Sandro. The zebrafish: a preclinical screening model for the optimization of nanomedicine formulations. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Monnard, Arnaud. An optogenetic tool to study asymmetric cell division. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Brkić, Šime. Molecular regulation of intussusceptive angiogenesis by ephrinB2/EphB4 signaling and its therapeutic potential. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Harmansa, Stefan. Nanobodies as novel tools to study morphogen function "in vivo". 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Pisarsky, Laura Estelle. Angiogenesis : from tumor initiation to therapeutic resistance. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Enderle, Leonie. Exploring the developmental functions of fat cadherins in Drosophila and mammals. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Alborelli, Ilaria. Characterization of the subcellular localization of the TGF-β receptors in the wing imaginal disc. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Metzler, Mario. In situ genetic dissection of the boundary element Miscadestral pigmentation in the Bithorax complex of Drosophila melanogaster. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Aydogan, Vahap. Understanding endothelial cell behaviors during sprouting angiogenesis. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Gaudiello, Emanuele. Engineering cell-based patches as controlled VEGF-releasing devices for therapeutic angiogenesis. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Tsankova, Anna. Myosin dynamics during asymmetric stem cell division. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Leonards, Katharina. Modelling and targeting epigenetic regulators in acute leukemia. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Lee, Ying Ying. Bone morphogenetic protein signaling in structural plasticity of cerebellar mossy fibers. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Cunha, Carolina Maria Medeiros da. Mesenchymal stromal cell (MSC)- based control of angiogenesis and inflammation in cartilage formation. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Bill, Ruben. Mechanisms of action and resistance to anti-angiogenic small-molecule tyrosine kinase inhibitors in preclinical breast cancer and pancreatic neuroendocrine tumor mouse models. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Stracka, Daniele. Upstream regulation of yeast TOR complexes. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Kletenkov, Konstantin. The role of the HIV-1 protease substrate in therapy resistance. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Bader, Joëlle. Dynamics of HIV-1 tropism during immune recovery driven by combination antiretroviral therapy. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Todorov, Atanas. Endochondral ossification - towards a clinical translation. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Sauteur, Loïc. "In vivo" analysis of junctional dynamics underlying angiogenic cell behaviors. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Nair, Anjana Ramdas. Investigating the cellular and molecular mechanisms involved in establishing and maintaining centrosome asymmetry in Drosophila neuroblasts. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Bieli, Dimitri. Part I: Studies on the Drosophila selector gene apterous and compartment boundary formation. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Pignatti, Emanuele. Targeting canonical BMP signaling : SMAD4 in limb patterning and differentiation. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Groppa, Elena. Mechanisms of vascular morphogenesis and stabilization by VEGF dose. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Sacchi, Veronica. Highly tunable delivery of matrix-bound growth factors for therapeutic angiogenesis. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Martin, Katrin. Growth-factor-induced, persistent fibroblast migration is mediated by mechanical insulation of cell front and back. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Sur Chowdhury, Chanchal. Neutrophil extracellular traps in inflammatory disorders. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Wu, Xiaomo. Homeotic transformation induced by protein transduction. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Arquint, Christian. On the function and regulation of human STIL - a centrosomal protein implicated in autosomal recessive primary microcephaly. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Schneider, Ralph Philipp. The TRF1 telomere protein is essential for the generation and maintenance of iPS cells and marks both pluripotent and adult stem cells. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Lenard, Anna. Dynamic cell rearrangements shape the cranial vascular network of developing Zebrafish embryos. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Reginato, Silvia. Promoting vessel stabilization : toward a safe mode of therapeutic angiogenesis. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Kuert, Philipp A.. Neuroblast lineage identification and Hox gene action during postembryonic development of the tritocerebrum and subesophageal ganglion in the "Drosophila" brain. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Bourgine, Paul. Combination of cell immortalization and apoptosis induction to engineer decellularized matrices as bone graft materials. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Heck, Chantal. New players, old suspects and a novel line of action in EMT. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Blum, Yannick. Cellular mechanisms during vascular development. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Kohler, Reto. Functional characterization of human NDR kinases : novel regulatory mechanisms and a path towards direct substrates. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Osterwalder, Marco. Genome-wide identification of Hand2 target regions in mouse embryos using dRMCE, a new genetic tool. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Krudewig, Alice. Junctional remodeling during angiogenesis : the role of Claudin5 during ISV formation in Zebrafish. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Trani, Marianna. Cellular and molecular mechanisms of VEGF-induced dose-dependent angiogenesis. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Waldmeier, Lorenz. Epithelial to mesenchymal transition in breast cancer : a novel murine model system and the regulatory role of tead transcription factors. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Herwig, Lukas Walter. Morphogenetic mechanisms of blood vessel fusion in the Zebrafish embryo. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Gruber, Dorothea Cornelia. Exploring functional mechanisms underlying tumor initiation, EMT and cell migration. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Topf, Ulrike. Investigations on the functions ot "ten-1" during embryonic development in "Caenorhabditis" elegans. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Helmrich, Uta. VEGF-expressing mesenchymal stem cells for improved angiogenesis in regenerative medicine : a bone tissue engineering approach. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Francioli, Silvia. Influence of chondrocytes differentiation stage on the capacity to generate cartilaginous tissue in vitro. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Izergina, Natalya. Postembryonic development of amplifying neuroblast lineages in the "Drosophila" brain : proliferation, differentiation and projection patterns. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Gonçalves, Alexandre. Epithelial-mesenchymal feedback signalling during vertebrate organogenesis : genetic analysis of BMP-Gremlin1 antagonistic interactions. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Schaub, Franz Xaver. Clonal evolution of mutation events in myeloproliferative neoplasms. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Sürücü, Banu. Regulation of protein kinase B (PKB/Akt) by DNA-dependent protein kinase (DNA-PK) under physiological conditions. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Kaulich, Manuel. Functional characterization of PICH, a DNA-dependent ATPase required for faithful chromosome segregation during mitosis. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Weiss, Alexander. Regulation of Dpp target genes by Mad/Medea and Brinker. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Lin, Li. Clonal analysis of growth behaviors during "Drosophila" larval tracheal development. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Liu, Ting. Identification of cooperating genetic events in acute leukemia. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Bozulic, Lana. Regulation and functions of protein kinase B in DNA damage signaling. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Bénazet, Jean-Denis. Interlinked signaling feedback loops and self-regulation during vertebrate limb development. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Bennion, Janis Michelle. "Drosophila" genetics as a tool in the search for novel components of the S6 kinase signaling pathway. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Dalvai, Mathieu. The versatile transcription factor Oct-1 : a crucial protein in embryonic development and a key component of the stress cellular response. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Trzebiatowska, Agnieszka. "Caenorhabditis elegans" TEN-1 is essential for basement membrane function. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Zhang, Jian. Identification of novel germline mutations in hereditary colorectal cancer patients and characterization of somatic alterations in their tumors. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Pan, Dejing. Transforming growth factor-ß (TGF-ß) signaling in hematopoiesis and tumorigenesis. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Blättler, Sharon. Mechanistic studies of the phenobarbital-type induction of cytochromes P450 : role of AMP-activated protein kinase. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Jäggi, Fabienne. The role of Sprouty4 in development and cancer and functional consequences of Sprouty interacting with Caveolin-1. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Kaeser, Patrick. Analysis of in vivo functions of Memo in embryonic and mammary gland development. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Schmutz, Cornelia. Characterization of the RhoGAP proteins RGA-3 and RGA-4 and the centrosomal protein SAS-5 in the early "Caenorhabditis elegans" embryo. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Röck, Salome. The function of the protein phosphatase Glc7p in transcription termination, RNA processing and transcriptional regulation of ribosomal protein genes. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Liu, Kun. Genetic studies of familial myeloproliferative disorders. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Plachta, Nicolas. Mouse embryonic stem cells as a new discovery tool in neurobiology. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Grotegut, Stefan. The role of hepatocyte growth factor/scatter factor in hepatoblastoma and hepatocellular carcinoma progression. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Molle, Klaus-Dieter. Regulation of the mammalian target of rapamycin complex 2 (mTORC2). 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Cabernard, Clemens. Studying fibroblast growth factor (FGF) mediated cell migration in "Drosophila" larval air sacs. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Stegert, Mario Reinhard. Functional characterisation of the mammalian NDR1 and NDR2 protein kinases and their regulation by the mammalian Ste20-like kinase MST3. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Neumann, Marc. Epithelial cell rearrangements during tubular organ formation. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Dossenbach, Caroline. Functional dissection of the "Drosophila melanogaster" fibroblast growth factor signalling pathway in branching morphogenesis of the developing tracheal system. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Pauli, Tobias Samuel. Molecular genetic analysis of a "sine oculis" enhancer and the "leventina" gene as a model system to study human macular degeneration in "Drosophila". 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Busch, Karl Emanuel. Coordinated activities of microtubule-associated proteins in spatial cytoskeleton organisation and the mechanisms mediating their microtubule plus end-tracking. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Isler, Silvia G.. SPARC-like 1 (SPARCL1), a gene downregulated in non-small cell lung cancer. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Hartmann, Britta. Characterization of Schnurri : an integral component of the Dpp-signaling pathway in "Drosophila melanogaster". 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Ribeiro, Carlos. Cellular and molecular analysis of branching morphogenesis in "Drosophila melanogaster". 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Martinelli, Cosimo. Molecular origin of mesoderm : conservation of T-box genes in non-bilaterian animals. 2003, Doctoral Thesis, University of Basel, Faculty of Science.

Marone, Romina. The ErbB2 receptor and breast carcinoma cell migration : memo is a novel mediator of cell motility. 2003, Doctoral Thesis, University of Basel, Faculty of Science.