Browse by Basel Advisors

Doctoral Thesis

Silbermann, Marleen. Kinetic and Thermodynamic Characterization of the Bacterial Lectin FimH. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Conti, Gabriele. Synthesis of glycomimetics of the natural Siglec-8 ligand and their pharmacodynamic characterization. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Aliu, Butrint. Development of therapeutic glycopolymers for the treatment of peripheral neuropathies and viral infections. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Dätwyler, Philipp. Oral bioavailability of carbohydrate mimetics : an "in vitro" and "in vivo" evaluation. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Frei, Priska. Target-directed dynamic combinatorial chemistry : potentials and pitfalls of an innovative screening approach. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Sager, Christoph Philipp. In-silico evaluation of carbohydrate–lectin interactions : bridging oligosaccharides and glycomimetics. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Kroezen, Blijke. Design, synthesis and biological evaluation of carbohydrate-mimetics for Siglec-8: a novel target for asthma. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Zihlmann, Pascal. Biophysical characterization of carbohydrate-lectin interactions. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Eriṣ, Deniz. Biological characterization of the bacterial Adhesin FimH — implications for drug design. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Herrendorff, Ruben. Novel therapeutic approaches for neuromuscular diseases. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Assmus, Frauke. Artificial tissue binding models : development and comparative evaluation of high - throughput lipophilicity assays and their use for PET tracer optimization. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Zierke, Mirko. Structure elucidation of selectin antagonists in solution and synthesis of sialyl Lewis x mimics pre-organized in their bioactive conformation. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Kleeb, Simon. Physicochemical and pharmacokinetic characterization of carbohydrate mimetics. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Pang, Lijuan. Antagonizing the adhesion of type 1 fimbriae - mediated Escherichia coli - a novel therapy for urinary tract infections. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Sigl, Anja. FimH antagonists and their therapeutic options in urinary tract infection : an example of an anti-adhesive therapy for infectious diseases. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Bezençon, Jacqueline. The potential of in vitro pharmacokinetic profiling to predict oral bioavailability of carbohydrate mimetics and cyclic hexapeptides. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Schönemann, Wojciech. Synthesis of novel high-affinity FimH antagonists with improved pharmacokinetic properties. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Navarra, Giulio. Synthesis and evaluation of glycomimetics : tool compounds binding to the FimH adhesin for analytical applications and new antagonists of the PapG-II adhesin. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Mayer, Katharina. Synthesis and evaluation of glycomimetic antagonists for the lectins DC-SIGN and FimH. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Abgottspon, Daniela. In vitro and in vivo characterization of FimH antagonists for anti-adhesion therapy - an alternative therapeutic approach against urinary tract infection. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Preston, Roland Christopher. Lectins as drug targets : functional, structural, and pharmacological insights into E-selectin and FimH. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Teppner, Marieke. Biomarkers for metabolic drug activation : towards an integrated risk assessment for drug-induced liver injury (DILI). 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Lemme, Katrin. Thermodynamic evaluation of carbohydrate-lectin interactions. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Scharenberg, Meike. Biological characterization of the lectins DC-SIGN and FimH : putative targets for novel anti-infectives. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Weckerle, Céline. E-selectin antagonists: fragment-based drug discovery and lead optimization by NMR and BIAcore. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Wittwer, Matthias Beat. The PADMET platform - pharmacokinetic characterization of carbohydrate mimetics. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Binder, Florian. E- and P-selectin : differences and similarities guide the development of novel selectin antagonists. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Egger, Jonas. Development and synthesis of nanomolar e-selectin antagonists using a fragment-based approach. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Vogelsgesang, Matthias David. Pharma² [pharmasquare] : Entwicklung eines Konzepts für "Distance Learning" in den pharmazeutischen Wissenschaften. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Saeed, Muhanned. Pharmaceutical tablets and near-infrared spectral information : investigation of sampled tablet sections and press effect on predictions. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Mesch, Stefanie. Synthesis and biological evaluation of carbohydrate-mimetics as ligands for Siglecs. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Perchuć, Anna Maria. Purification and preliminary characterization of "Bothrops moojeni" venom components active on haemostasis : ("Botmo thesis"). 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Stokmaier, Daniela. Targeting hepatocytes via the asialoglycoprotein-receptor. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Yu, Jing. Expression and characterization of E-LecEGF for structural study and assay development. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Strasser, Daniel. Real-time drug discovery : characterization of the myelin-associated glycoprotein/ligand interaction. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Knecht, Steven. Development of new tags for solid-phase peptide synthesis. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Titz, Alexander. E-selectin and the natural tetrasaccharide ligand sialyl Lewis*. the importance of pharmacophore pre-organization in glyco-mimetics. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Riva, Claudia. Targeting the liver via the asialoglycoprotein-receptor : synthesis of directed small molecule libraries for the H1-CRD. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Tschopp, Lionel. Exploring the binding site of E-selectin from an enthalpic or entropic point of view. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Khorev, Oleg. Design and synthesis of high affinity ligands for the asialoglycoprotein receptor (ASGP-R). 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Johansson, Anna Karin. Linking structure and function of the asialoglycoprotein receptor H1-CRD using site-directed mutagenesis and isotope labeling. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Vögtli, Alexander. Entwicklung einer Theorie über die wissenschaftlichen Bilder und Anwendung auf die Wahlvorlesung "Aktiver und passiver Transport durch Membranen". 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Schwizer, Daniel. Lead optimization studies on E-selectin antagonists. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Weber, Christina. Entwicklung und Evaluation mediendidaktischer Konzepte zur Computer-basierten Lernerfolgskontrolle im Fach Molekulare Pharmazie. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Marti, Sébastien Jérôme Georges. Towards the synthesis of a macrocyclic E-selectin antagonist. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Studer-Imwinkelried, Matthias. NeuroCarb : artificial neural networks for NMR structure elucidation of oligosaccharides. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Stöckli, Andreas. NeuroCarb : Anwendung von künstlichen neuronalen Netzwerken für die NMR Strukturaufklärung von Oligosacchariden. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Porro, Michele Giovanni Antonio. Analysis, design and "in silico" evaluation of e-selectin antagonists. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Shelke, Sachin Vilasrao. Exploring the carbohydrate-binding sites of myelin-associated glycoprotein (MAG) and its ligands by a integrated dynamic approach. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Storch, Daniel. Neue, radioaktiv markierte und Magnet-Resonanz-aktive Somatostatinanaloga zur besseren Diagnose und zielgerichteten radionuklidtherapie von neuroendokrinen Tumoren. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Müller, Christian. Selectin antagonists : synthesis and conformational comparison of C- and O-glycosidic tetrasaccharide mimetics related to sialyl Lewis*. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Nowbakht, Pegah. Tumor recognition by natural killer cells in acute myeloid leukemia and after hematopoietic stem cell transplantation. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Ricklin, Daniel. Surface plasmon resonance applications in drug discovery : with an emphasis on small molecule and low affinity systems. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Dragic, Zorica. E-selectin as anti-inflammatory drug target : expression, purification and charactrization for structural studies : assay development for antaginists evaluation. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Visekruna, Tamara. Sialyltransferases: expression and application for chemo-enzymatic syntheses. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Born, Rita. Benefit and application of antibodies against the H1 carbohydrate recognition domain of the human hepatic asialoglycoprotein receptor. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Gao, Gan-Pan. Synthesis of antagonists of Myelin-associated glycoprotein (MAG) for conformational and SAR studies. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Rock, Peter. Cultured fibroblasts as a model for methionine metabolism in man : effect of growth and substrates on homocysteine and related metabolites. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Lichtsteiner, Salome Katharina. Entwicklung und Evaluation der Blended-Learning-Umgebung pharmasquare (pharma²) : Kombination von Präsenzlehrveranstaltungen und E-Learning am Beispiel der pharmazeutischen Chemie. 2004, Doctoral Thesis, University of Basel, Faculty of Science.