Browse by Basel Advisors

Doctoral Thesis

Louche, Chris. Investigation and targeting of early degenerative response in retinal cells in Ischemia-Reperfusion glaucoma mouse model: paving the way for therapeutic neuroprotection strategy. 2024, Doctoral Thesis, University of Basel, Faculty of Science.

Czernecki, Charlotte/CC. Probing cholesterol homeostasis in models of neurodevelopmental disorders. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Thürkauf, Marco. Deciphering the function of candidate genes in skeletal muscle aging using AAV-CRISPR/Cas9. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Schneider-Heieck, Konstantin. Characterization of transcriptional modulators involved in exercise-induced adaptive remodeling of skeletal muscle. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Ham, Alexander. Studying the healthy, denervated and aged neuromuscular system using single nuclei RNA-seq. 2023, Doctoral Thesis, University of Basel, Faculty of Science.

Leuchtmann, Aurel B.. Molecular transducers of exercise training adaptations in young and aged skeletal muscle. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Winkler, Sabine Celine/SCW. PKCγ-mediated phosphorylation of CRMP2 regulates dendritic outgrowth in cerebellar Purkinje cells. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Sanvee, Gerda Mawududzi. Molecular mechanisms of simvastatin-induced myopathy and insulin resistance. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Hauser, David. Regulation of synaptic adhesion molecules by RNA processing. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Eckhardt, Jan. Functional characterization of extraocular muscle in transgenic mouse models. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Maier, Geraldine. Investigating the role of the circadian clock and timed exercise on mouse skeletal muscle function. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Wu, Qinwei. Molecules Involved in Purkinje Cell Dendritic Development and Spinocerebellar Ataxias. 2020, Doctoral Thesis, University of Basel, Faculty of Medicine.

Falcetta, Denis. Understanding the pathomechanisms leading to muscle alterations in Myotonic Dystrophy type 1: Consequences of CaMKII deregulation on the maintenance of neuromuscular junctions. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Federer-Gsponer, Joël. DNA content based flow sorting combined with genomic high-resolution profiling in the context of the development of castration resistance in prostate cancer. 2020, Doctoral Thesis, University of Basel, Cross-disciplinary Subjects.

Flores-Dominguez, Diana. The role of the Calcium-binding of Copine-6 in synapse function and plasticity. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Chojnowska, Kathrin. Deciphering additional mechanisms of mTORC1 signaling in skeletal muscle. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Battilana, Fabienne. The effect of age and exercise on the proprioceptive and vestibular system. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Kaiser, Marco. The role of mTORC1 in muscle proteostasis. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Weihrauch, Martin. Identification of novel synaptic components by transcriptome profiling of the murine neuromuscular junction. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Heim-Kupr, Barbara. Molecular mechanisms of the transcriptional regulation by PGC-1α/β in skeletal muscle. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Heim, Philippe. Regulation of glucose uptake in neonatal rat cardiomyocytes by Neuregulin1β. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Schnyder, Svenia. Regulation of skeletal muscle and kidney metabolism by the PGC-1 family of transcriptional coactivators. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Rion, Nathalie. Understanding the role of mTORC1 and mTORC2 in embryonic and adult myogenesis. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Lebboukh, Sonia. Cardiac effects of ovarian hormones and gender in a mouse model of obesity. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Gill, Jonathan François. Neuronal control of energy balance and modulation of muscle aging by the transcriptional coactivator PGC-1α. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Skachokova, Zhiva Kalinova. Seeding properties of amyloid-beta and tau in the cerebrospinal fluid. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Berner, David. GABAB receptor-associated KCTD proteins as molecular linkers to downstream signaling complexes. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Svensson, Sven Ove Kristoffer. Transcriptional regulation of kidney and skeletal muscle metabolism by the coactivator PGC-1α. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Herrendorff, Ruben. Novel therapeutic approaches for neuromuscular diseases. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Kim, Munkyung. Characterization of Alport syndrome and DPP9 protease using Col4a3 knock-out mice and DPP9 protease dead mutant mice. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Angliker, Nico. Distinct and common functions of mTORC1 and mTORC2 in Purkinje cells. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Ramadoss, Archana. Contribution of 3q26-29 gene cluster to glioma invasion. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Ormazabal, Maitea Guridi. Skeletal muscle mTORC1 regulates whole-body metabolism. 2015, Doctoral Thesis, University of Basel, Faculty of Science.

Olivieri, Stefano. Biosynthesis and release of brain-derived neurotrophic factor : a study using neurons derived from embryonic stem cells. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Dinulović, Ivana. PGC-1α modulates skeletal muscle regeneration by affecting immune response and satellite cell behavior. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Chip, Sophorn. Cortical organotypic slice cultures as a tool to analyze the neurovascular unit in hypoxia/ischemia and hypothermia-induced neuroprotection. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Pérez-Schindler, Joaquín. Regulation of skeletal muscle plasticity by the transcriptional coregulators PGC-1α and NCoR1. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Barešić, Mario. The molecular dissection of the regulation of PGC-1α and the genome-wide activity of its transcriptional network in skeletal muscle cells. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Di Fulvio, Sabrina. Characterization of the dysferlin protein and its binding partners reveals rational design for therapeutic strategies for the treatment of dysferlinopathies. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Costa, Luigi. The interaction of tiotropium with long lasting β2-agonists on lung cell function. 2013, Doctoral Thesis, University of Basel, Faculty of Science.

Gugger, Olivia S.. Mechanisms and consequences of reduced dendritic growth of cerebellar Purkinje cells. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Feltrin, Daniel. Local mRNA translation in the regulation of neurite outgrowth. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Tchorz, Jan Stephan. Notch2 signaling in development and cancer. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Thomanetz, Venus. mTORC2 controls neuron size and Purkinje cell morphology independent of mTORC1. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Haefeli, Roman Hans. Molecular effects of Idebenone. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Lustenberger, Regula Maria. The role of raptor during brain development and in adult forebrain neurons. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Betz, Charles. mTOR complex 2 - akt signaling is physically and functionally at mam. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Romanino, Klaas Emilio Antonius Anna. The role of mTOR complex 1 in skeletal muscle. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Reinhard, Judith. The function of Copine 6 in the brain. 2012, Doctoral Thesis, University of Basel, Faculty of Science.

Abdel Aziz, Said. Identification of serine 867 as new phosphorylation site on the GABA(B) receptor : characterization of physiological effects. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Rosc-Schlüter, Berit Ines. NADPH oxidase (NOX) in the heart : the interplay of NOX-derived ROS in β1-integrin-induced survival signalling. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Laxhmi Chellappa, Sarah. Circadian and ultradian NREM-REM sleep modulation of dream recall : effects of age and spectral activity. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Yazdani Shektaei, Morteza. Disease modelling of a human neurodevelopmental disorder using mouse embryonic stem cells. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Escher, Claudia Andrea. Proteomic profiling of Duchenne muscular dystrophy : protein patterns and candidate markers of disease. 2011, Doctoral Thesis, University of Basel, Faculty of Science.

Kriz, Alexander. Copine 6, a novel calcium sensor translating synaptic activity into spine plasticity : or, "Copine 6 a brainsporter in action". 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Cybulski, Nadine. New insights into the "in vivo" and "in vitro" functions of mammalian TOR complex 2. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Bonnici, Brenda. Axonal regeneration in hippocampal and spinal cord organotypic slice cultures. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Miglino, Nicola Romolo. Novel molecular pathologies in asthma and COPD. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Lutz, Roman. Modulation of cell-matrix adhesions to affect mechanotransduction. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Cloëtta, Dimitri Yves Reto. A conditional mouse model for the characterization of mTORC1 function in muscle and brain. 2010, Doctoral Thesis, University of Basel, Faculty of Science.

Bentzinger, Conrad Florian. Function of mTOR complex 1 and 2 in skeletal muscle. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Clavaguera, Florence. Initiation and spreading of Tau pathology. is β-Amyloid the only key? 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Egler, Viviane. A combinatorial preclinical in vitro strategy against human glioblastoma cells. specific targeting of protein kinases, histone deacetylases and glycolysis. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Guetg, Nicole. GABAB receptor, localization and regulation. 2009, Doctoral Thesis, University of Basel, Faculty of Science.

Zhang, Yan-Ping. Optical analysis of synaptic plasticity in rat hippocampus. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Giacometti, Emanuela. Epigenetic and central nervous system function : insights from the study of the rett syndrome mouse model. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Lange, Katrin. Characterization of tenascin-C-induced signaling in tumorigenesis. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Maj, Marcin. Functional characterization of MuSK, receptor tyrosine kinase required for the formation and the maintenance of nerve-muscle synapses : "in vivo" and "in vitro" approaches. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Annaheim, Christine. Untersuchungen über die funktionelle Rolle des Neurotrophinrezeptors p75 basierend auf embryonalen Stammzellen der Maus. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Buser, Andres. The septin cytoskeleton is associated with distinct myelin structures of the central and peripheral nervous system. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Rauskolb, Stefanie. Brain-derived neurotrophic factor : generation and characterization of adult mice lacking BDNF in the adult brain. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Polak, Pazit. Regulation of adipogenesis and adipose maintenance by the mammalian TOR complex 1. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Heitz, Stéphane. Neuronal death mechanisms in cerebellar Purkinje cells. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Sivasankaran, Balasubramanian. The role of NOTCH2 gene in human malignant glial brain tumours. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Kenzelmann Broz, Daniela. Teneurins in development and disease. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Zeis, Thomas. Characterization of molecular alterations in normal appearing white matter of multiple sclerosis brain tissue and its animal model experimental autoimmune encephalomyelitis. 2008, Doctoral Thesis, University of Basel, Faculty of Science.

Failly, Mike. Combinatorial strategy using protein kinase inhibitors and a cytotoxic compound for highly resistant glioblastoma cells : "in vitro studies". 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Kuisle, Mira. Pacemaker channel function and regulation in the healthy and epileptic thalamus. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Flück, Bettina. Particular aspects of myelin-axon interactions in health and disease : the expression of myelin-associated glycoprotein isoforms in CNS and PNS. Early axonal pathology in the dysmyelinating peripheral neuropathy CMT1A. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Vrieseling, Eline. Assembly of sensory-motor connectivity in the spinal cord of mice. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Degen, Martin. Tenascins : prominent molecules in tumor stroma. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Ruiz, Christian. Identification and validation of novel amplification target genes in human breast cancer. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Cueni, Lucius D.. Low-voltage-activated Ca²+ channels. from burst generators to Ca²+ sources in thalamic oscillatory activity. 2007, Doctoral Thesis, University of Basel, Faculty of Science.

Ermini, Florian V.. Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Sadhu, Anirban. "Role of the neuronal protein Cap23 in the maturation and maintenance of dendritic arbors in-vivo". 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Schrenk, Katrin. The role of amyloid precursor proteins : studies using neurons generated from wild-type and mutant embryonic stem cells. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Garcia, Pilar. Molecular insights into the regulatory interactions of Dystrophia myotonica protein kinase. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Scotton, Patrick. New approaches to identify interactors of MuSK, a receptor tyrosine kinase required for the formation of the nerve-muscle synapse. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Güntert, Andreas. Characterization of amyloid-ß and other proteins related to Alzheimer's disease, their role in neurodegeneration and biomarker discovery. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Bittcher, Godela. The role of transmembrane agrin in reorganizing the cytoskeleton in neurons and non-neuronal cells. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Di Scala, Franck. Untersuchung von Muskelgewebe amyotorpher lateraler Sklerose : Etiologie, Diagnose und therapeutische Aspekte. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Hrus, Ana. Identification and characterization of agrin in "Caenorhabditis elegans". 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Plachta, Nicolas. Mouse embryonic stem cells as a new discovery tool in neurobiology. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Bolmont, Tristan. Mechanisms underlying the initiation of cerebral betaamyloidosis and neurofibrillary tau pathology : new insights form transgenic mice. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Galic, Milos. Regulation of dendritic spine morphogenesis and synapse formation by copines. 2006, Doctoral Thesis, University of Basel, Faculty of Science.

Gupta, Anurag Kumar. Immune-modulation by the placenta and its dysregulation in preeclampsia : role of syncytiotrophoblast microparticles and cytokines. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Niederkofler, Vera. Identification and functional characterization of the RGM family in mouse. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Meinen, Sarina. Artificial restoration of the linkage between laminin and dystroglycan ameliorates the disease progression of MDC1A muscular dystrophy at all stages. 2005, Doctoral Thesis, University of Basel, Faculty of Science.

Middendorp, Oliver M.. Yeast growth selection system for the identification of cell-active inhibitors of [beta]-secretase. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Frère, Samuel. GABA signaling in the thalamus. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Bissière, Stéphanie. Dopaminergic modulation of synaptic transmission and plasticity in the lateral amygdala. 2004, Doctoral Thesis, University of Basel, Faculty of Science.

Hofsäss, Ulrike. Identification of genes differentially expressed in rat brain during postnatal development. 2003, Doctoral Thesis, University of Basel, Faculty of Science.

Erb, Michael. Differential expression and MAL-dependent targeting of the L-MAG and S-MAG isoforms to myelin membranes. 2003, Doctoral Thesis, University of Basel, Faculty of Science.

Boncristiano, Sonia. Cerebral amyloidosis in a transgenic mouse model of Alzheimer's disease : impact and therapy. 2003, Doctoral Thesis, University of Basel, Faculty of Science.

Kong, Xian Chu. RNA interference: a new tool to study gene functions in adult mammalian muscle "in vivo". 2003, Doctoral Thesis, University of Basel, Faculty of Science.

Bondolfi, Luca E.. Neurodegeneration and neurogenesis in mouse models of aging and Alzheimer's disease. 2003, Doctoral Thesis, University of Basel, Faculty of Science.

De Paola, Vincenzo. Pre-synaptic terminal dynamics in the hippocampus. 2003, Doctoral Thesis, University of Basel, Faculty of Science.