FLOTAC: a promising technique for detecting helminth eggs in human faeces
Date Issued
2009-01-01
Author(s)
Knopp, Stefanie
Rinaldi, Laura
Mohammed, Khalfan A
N'Goran, Eliézer K
Stothard, J Russell
Cringoli, Giuseppe
Rollinson, David
DOI
10.1016/j.trstmh.2009.05.012
Abstract
There is a tendency to neglect diagnostic issues in the era of 'preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management and monitoring of community-based control programmes. Implicit is a diagnostic dilemma: the more effective interventions are in reducing helminth egg excretion, the less sensitive direct parasitological tests become. Here, experiences gained thus far with the FLOTAC technique for diagnosing common soil-transmitted helminth infections are summarized. A single FLOTAC has higher sensitivity than multiple Kato-Katz thick smears in detecting low-intensity infections. Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases