Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer
Date Issued
2010-01-01
Author(s)
DOI
10.1186/1471-2407-10-93
Abstract
The VEGF family of ligands and receptors are intimately involved in tumor angiogenesis, lymphangiogenesis and metastasis. The evaluation of VEGF ligand/receptor ratios may provide a more profound understanding of the involvement of these proteins in colorectal tumour progression. The aim of this study was to elucidate the role of the VEGF ligand/receptor ratios on tumour progression and metastasis in patients with mismatch repair-proficient colorectal cancer.