Extensive oscillatory gene expression during "C. elegans" larval development
Date Issued
2015
Author(s)
Hendriks, Gerardus Johannes
DOI
10.5451/unibas-006762575
Abstract
Oscillations are common features in mathematics, physics and biology. In biology, circadian oscillations, for example, allow organisms to keep time and modify their biology and behavior accordingly. Other types of oscillating mechanisms allow for the precise timing of developmental events. We found that nearly 19% of the C. elegans transcriptome shows extensive and robust transcriptionally driven oscillations of gene expression during larval development. In the work presented in the following dissertation, we characterised this network of oscillating gene expression.
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