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Hyperprolactinemia in early psychosis - not only due to antipsychotics

Date Issued
2010-01-01
Author(s)
Aston, Jacqueline
Rechsteiner, Evelyne
Bull, Nadine
Borgwardt, Stefan  
Gschwandtner, Ute  
Riecher-Rossler, Anita  
DOI
10.1016/j.pnpbp.2010.02.019
Abstract
Hyperprolactinaemia is often found in patients with schizophrenia and usually considered a consequence of antipsychotics. Prolactin levels were measured in 43 At-Risk Mental State individuals (ARMS) and 26 patients with First Episode Psychosis (FEP). Hyperprolactinaemia was found in 25.6% of ARMS and 46.2% of FEP. Within 60 antipsychotic-naïve ARMS and FEP, hyperprolactinaemia was found in 26.7%. Hyperprolactinaemia may be pre-existing in a subgroup of patients with schizophrenia.
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