Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients

Santoro, A

doi:10.1093/annonc/mdp357

Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients

Date Issued

2010-01-01

Author(s)

Cappuzzo, F

Tallini, G

Finocchiaro, G

Wilson, R S

Ligorio, C

Giordano, L

Toschi, L

Incarbone, M

Cavina, R

Terracciano, L

Roncalli, M

Alloisio, M

Varella-Garcia, M

Franklin, W A

Santoro, A

DOI

10.1093/annonc/mdp357

Abstract

The purpose of this study is to investigate the prognostic role of insulin-like growth factor receptor 1 (IGF1R) expression in surgically resected non-small-cell lung cancer (NSCLC). Patient characteristics and methods: This retrospective study was conducted in 369 stage I-II-IIIA, surgically resected, NSCLC patients. Patients exposed to anti-epidermal growth factor receptor (EGFR) agents were excluded. IGF1R expression was evaluated by immunohistochemistry in tissue microarray sections.