Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1

Wagner, Gerhard

doi:10.1007/s12104-009-9194-0

Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1

Date Issued

2010-01-01

Author(s)

Hiller, Sebastian

Malia, Thomas J.

Garces, Robert G.

Orekhov, Vladislav Y.

Wagner, Gerhard

DOI

10.1007/s12104-009-9194-0

Abstract

The voltage dependent anion channel (VDAC) forms a channel for metabolites and nutrients in the outer membrane of mitochondria, and it is also involved in apoptotic pathways. Here, we report sequence-specific NMR assignments for the isoform 1 of human VDAC reconstituted in lauryldimethylamine oxide (LDAO) detergent micelles. The assignments were deposited in the BMRB data base with accession number 16381.