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Dpp/BMP signaling in flies: from molecules to biology

Hamaratoglu, Fisun and Affolter, Markus and Pyrowolakis, George. (2014) Dpp/BMP signaling in flies: from molecules to biology. Seminars in cell & developmental biology, Vol. 32 , p. 128–136.

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Official URL: http://edoc.unibas.ch/dok/A6263203

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Abstract

Decapentaplegic (Dpp), the fly homolog of the secreted mammalian BMP2/4 signaling molecules, is involved in almost all aspects of fly development. Dpp has critical functions at all developmental stages, from patterning of the eggshell to the determination of adult intestinal stem cell identity. Here, we focus on recent findings regarding the transcriptional regulatory logic of the pathway, on a new feedback regulator, Pentagone, and on Dpp's roles in scaling and growth of the Drosophila wing.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Cell Biology (Affolter)
UniBasel Contributors:Affolter, Markus
Item Type:Article, refereed
Article Subtype:Book Review
Publisher:Academic Press
ISSN:1084-9521
Note:Publication type according to Uni Basel Research Database: Journal item
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Last Modified:07 Nov 2014 08:28
Deposited On:07 Nov 2014 08:28

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