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Tidal volume single breath washout of two tracer gases : a practical and promising lung function test

Singer, Florian and Stern, Georgette and Thamrin, Cindy and Fuchs, Oliver and Riedel, Thomas and Gustafsson, Per and Frey, Urs and Latzin, Philipp. (2011) Tidal volume single breath washout of two tracer gases : a practical and promising lung function test. PLoS ONE, Vol. 6, H. 3 , e17588.

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Official URL: http://edoc.unibas.ch/dok/A6006446

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Abstract

Small airway disease frequently occurs in chronic lung diseases and may cause ventilation inhomogeneity (VI), which can be assessed by washout tests of inert tracer gas. Using two tracer gases with unequal molar mass (MM) and diffusivity increases specificity for VI in different lung zones. Currently washout tests are underutilised due to the time and effort required for measurements. The aim of this study was to develop and validate a simple technique for a new tidal single breath washout test (SBW) of sulfur hexafluoride (SF(6)) and helium (He) using an ultrasonic flowmeter (USFM).
Faculties and Departments:03 Faculty of Medicine > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) > Pädiatrie (Frey)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) > Pädiatrie (Frey)
UniBasel Contributors:Frey, Urs Peter
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Public Library of Science
e-ISSN:1932-6203
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:31 Aug 2018 06:40
Deposited On:25 Oct 2013 08:32

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