Siddharthan, Rahul and van Nimwegen, Erik. (2007) Detecting regulatory sites using PhyloGibbs. Methods in Molecular Biology, 395. pp. 381-402.
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Official URL: http://edoc.unibas.ch/dok/A5844325
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Abstract
PhyloGibbs is a program that uses Gibbs sampling to predict putative binding sites for transcription factors in DNA. It has two notable advances over previous algorithms for this task: it handles phylogenetically related sequence systematically, and it evaluates the significance of each predicted site via statistical sampling. In this article, we explain how to use PhyloGibbs effectively. We describe the essential command-line options in detail, and discuss other considerations that arise in practical situations.
| Faculties and Departments: | 05 Faculty of Science > Departement Biozentrum > Computational & Systems Biology > Bioinformatics (van Nimwegen) |
|---|---|
| UniBasel Contributors: | van Nimwegen, Erik |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Humana Press |
| ISSN: | 1064-3745 |
| e-ISSN: | 1940-6029 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Related URLs: | |
| Identification Number: |
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| Last Modified: | 12 Oct 2017 10:02 |
| Deposited On: | 08 Jun 2012 06:46 |
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