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TOR signalling and control of cell growth

Thomas, G. and Hall, M. N.. (1997) TOR signalling and control of cell growth. Current Opinion in Cell Biology, 9 (6). pp. 782-787.

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Official URL: http://edoc.unibas.ch/dok/A5258182

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Abstract

TOR, phosphatidylinositol 3-kinase, p70s6k, and 4E-BP1 have recently emerged as components of a major signalling pathway that is dedicated to protein translation and thus to cell growth. This pathway appears to be conserved, at least in part, in yeast, slime molds, plants, flies, and mammals. TOR and phosphatidylinositol 3-kinase control p70s6k and 4E-BP1, which, in turn, directly control the translation initiation machinery.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Hall)
UniBasel Contributors:Hall, Michael N.
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:0955-0674
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:09 Nov 2017 10:15
Deposited On:22 Mar 2012 13:19

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