Daubenberger, C.. (2023) Genetically modified malaria parasites as vaccine candidates. Trends in molecular medicine, 29 (1). pp. 1-3.
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Official URL: https://edoc.unibas.ch/92191/
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Abstract
Induction of sterile immunity against sporozoite and liver stages of malaria is a long-standing aim in vaccine development. Genetically engineered, attenuated sporozoites were systematically evaluated in animal models. Murphy et al. present the first, promising clinical trial of early arresting parasites, PfGAP3KO, confirming safety and demonstrating efficacy against homologous challenge.
| Faculties and Departments: | 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) 09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology (MPI) > Clinical Immunology (Daubenberger) |
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| UniBasel Contributors: | Daubenberger, Claudia |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| ISSN: | 1471-4914 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
| Identification Number: |
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| Last Modified: | 06 Jan 2023 07:55 |
| Deposited On: | 06 Jan 2023 07:55 |
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