Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030

Zare Jeddi, M. and Hopf, N. B. and Louro, H. and Viegas, S. and Galea, K. S. and Pasanen-Kase, R. and Santonen, T. and Mustieles, V. and Fernandez, M. F. and Verhagen, H. and Bopp, S. K. and Antignac, J. P. and David, A. and Mol, H. and Barouki, R. and Audouze, K. and Duca, R. C. and Fantke, P. and Scheepers, P. and Ghosh, M. and Van Nieuwenhuyse, A. and Lobo Vicente, J. and Trier, X. and Rambaud, L. and Fillol, C. and Denys, S. and Conrad, A. and Kolossa-Gehring, M. and Paini, A. and Arnot, J. and Schulze, F. and Jones, K. and Sepai, O. and Ali, I. and Brennan, L. and Benfenati, E. and Cubadda, F. and Mantovani, A. and Bartonova, A. and Connolly, A. and Slobodnik, J. and Bruinen de Bruin, Y. and van Klaveren, J. and Palmen, N. and Dirven, H. and Husøy, T. and Thomsen, C. and Virgolino, A. and Röösli, M. and Gant, T. and von Goetz, N. and Bessems, J.. (2022) Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020-2030. Environment international, 168. p. 107476.

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Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission's Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Environmental Exposures and Health Systems Research > Physical Hazards and Health (Röösli)
UniBasel Contributors:Röösli, Martin
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:28 Dec 2022 10:01
Deposited On:28 Dec 2022 10:01

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