Short-Term Effects of PM; 10; , NO; 2; , SO; 2; and O; 3; on Cardio-Respiratory Mortality in Cape Town, South Africa, 2006-2015

Adebayo-Ojo, Temitope Christina and Wichmann, Janine and Arowosegbe, Oluwaseyi Olalekan and Probst-Hensch, Nicole and Schindler, Christian and Künzli, Nino. (2022) Short-Term Effects of PM; 10; , NO; 2; , SO; 2; and O; 3; on Cardio-Respiratory Mortality in Cape Town, South Africa, 2006-2015. International Journal of Environmental Research and Public Health, 19 (13). p. 8079.

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The health effect of air pollution is rarely quantified in Africa, and this is evident in global systematic reviews and multi-city studies which only includes South Africa.; A time-series analysis was conducted on daily mortality (cardiovascular (CVD) and respiratory diseases (RD)) and air pollution from 2006-2015 for the city of Cape Town. We fitted single- and multi-pollutant models to test the independent effects of particulate matter (PM; 10; ), nitrogen dioxide (NO; 2; ), sulphur dioxide (SO; 2; ) and ozone (O; 3; ) from co-pollutants.; daily average concentrations per interquartile range (IQR) increase of 16.4 µg/m; 3; PM; 10; , 10.7 µg/m; 3; NO; 2; , 6 µg/m; 3; SO; 2; and 15.6 µg/m; 3; O; 3; lag 0-1 were positively associated with CVD, with an increased risk of 2.4% (95% CI: 0.9-3.9%), 2.2 (95% CI: 0.4-4.1%), 1.4% (95% CI: 0-2.8%) and 2.5% (95% CI: 0.2-4.8%), respectively. For RD, only NO; 2; showed a significant positive association with a 4.5% (95% CI: 1.4-7.6%) increase per IQR. In multi-pollutant models, associations of NO; 2; with RD remained unchanged when adjusted for PM; 10; and SO; 2; but was weakened for O; 3; . In CVD, O; 3; estimates were insensitive to other pollutants showing an increased risk. Interestingly, CVD and RD lag structures of PM; 10; , showed significant acute effect with evidence of mortality displacement.; The findings suggest that air pollution is associated with mortality, and exposure to PM; 10; advances the death of frail population.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Air Pollution and Health (Künzli)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Air Pollution and Health (Künzli)
UniBasel Contributors:Künzli, Nino and Probst-Hensch, Nicole and Arowosegbe, Oluwaseyi Olalekan and Schindler, Christian and Adebayo, Temitope
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:14 Dec 2022 09:38
Deposited On:14 Dec 2022 09:38

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