Retrosynthetic polyketide disconnections for unnatural aromatics

Wu, Xingxing and Sparr, Christof. (2022) Retrosynthetic polyketide disconnections for unnatural aromatics. Trends in chemistry, 4 (5). pp. 367-370.

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Polyketide synthases are extraordinarily complex enzymatic machineries that govern the assembly and cyclization of poly-β-carbonyl intermediates to an enormous diversity of natural products. Captivatingly, this biosynthetic strategy is transferable to the retrosynthetic analysis of unnatural aromatics, enabling strategic biomimetic polyketide cyclizations to design an extensive range of otherwise unrelated aromatic products.
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Organische Chemie (Sparr)
UniBasel Contributors:Sparr, Christof
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:16 Nov 2022 07:16
Deposited On:16 Nov 2022 07:16

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