Impact of psychological trauma on the development of psychotic symptoms : relationship with psychosis proneness

Spauwen, J. and Krabbendam, L. and Lieb, R. and Wittchen, H.-U. and van Os, J.. (2006) Impact of psychological trauma on the development of psychotic symptoms : relationship with psychosis proneness. British journal of psychiatry, Vol. 188. pp. 527-533.

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Official URL: http://edoc.unibas.ch/dok/A5253192

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Background The reported link between psychological trauma and onset of psychosis remains controversial. Aims To examine associations between self-reported psychological trauma and psychotic symptoms as a function of prior evidence of vulnerability to psychosis (psychosis proneness). Method At baseline, 2524 adolescents aged 14-24 years provided self-reports on psychological trauma and psychosis proneness, and at follow-up (on average 42 months later) participants were interviewed for presence of psychotic symptoms. Results Self-reported trauma was associated with psychotic symptoms, in particular at more severe levels (adjusted OR 1.89, 95% CI 1.16-3.08) and following trauma associated with intense fear, helplessness or horror. The risk difference between those with and without self-reported trauma at baseline was 7% in the group with baseline psychosis proneness, but only 1.8% in those without (adjusted test for difference between these two effect sizes: chi(2) = 4.6, P = 0.032). Conclusions Exposure to psychological trauma may increase the risk of psychotic symptoms in people vulnerable to psychosis.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Klinische Psychologie und Epidemiologie (Lieb)
UniBasel Contributors:Lieb, Roselind
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:25
Deposited On:22 Mar 2012 13:45

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