Chlamydomonas swims with two "gears" in a eukaryotic version of run-and-tumble locomotion

Polin, Marco and Tuval, Idan and Drescher, Knut and Gollub, J. P. and Goldstein, Raymond E.. (2009) Chlamydomonas swims with two "gears" in a eukaryotic version of run-and-tumble locomotion. Science, 325 (5939). pp. 487-490.

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The coordination of eukaryotic flagella is essential for many of the most basic processes of life (motility, sensing, and development), yet its emergence and regulation and its connection to locomotion are poorly understood. Previous studies show that the unicellular alga Chlamydomonas, widely regarded as an ideal system in which to study flagellar biology, swims forward by the synchronous action of its two flagella. Using high-speed imaging over long intervals, we found a richer behavior: A cell swimming in the dark stochastically switches between synchronous and asynchronous flagellar beating. Three-dimensional tracking shows that these regimes lead, respectively, to nearly straight swimming and to abrupt large reorientations, which yield a eukaryotic version of the "run-and-tumble" motion of peritrichously flagellated bacteria.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Infection Biology > Microbiology and Biophysics (Drescher)
UniBasel Contributors:Drescher, Knut
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:American Association for the Advancement of Science
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:23 Jun 2021 15:04
Deposited On:23 Jun 2021 15:04

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