Childhood separation anxiety and the risk of subsequent psychopathology : results from a community study

Brueckl, Tanja and Wittchen, Hans-Ulrich and Hoefler, Michael and Pfister, Hildegard and Schneider, Silvia and Lieb, Roselind. (2007) Childhood separation anxiety and the risk of subsequent psychopathology : results from a community study. Psychotherapy and Psychosomatics, 76 (1). pp. 47-56.

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Official URL: http://edoc.unibas.ch/dok/A5249003

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Objective: To examine the association between separation anxiety disorder ( SAD) and mental disorders in a community sample and to evaluate whether separation anxiety is specifically related to panic disorder with and without agoraphobia. Method: The data come from a 4-year, prospective longitudinal study of a representative cohort of adolescents and young adults aged 14-24 years at baseline in Munich, Germany. The present analyses are based on a subsample of the younger cohort that completed baseline and two follow-up investigations (n = 1,090). DSM-IV diagnoses were made using the Munich Composite International Diagnostic Interview. Cox regressions with time-dependent covariates were used to examine whether prior SAD is associated with an increased risk for subsequent mental disorders. Results: Participants meeting DSM-IV criteria for SAD were at an increased risk of developing subsequent panic disorder with agoraphobia (PDAG) (HR = 18.1, 95 5.6-58.7), specific phobia ( HR = 2.7, 95 generalized anxiety disorder ( HR = 9.4,95 sessive-compulsive disorder (HR = 10.7, 95 disorder ( HR = 7.7, 95 95 1.7-12.4). Increased hazard rates for PDAG ( HR = 4.2, 95 1.4-12.1), bipolar disorder type II ( HR = 8.1, 95 pain disorder ( HR = 1.9, 95 HR = 2.1,95 subthreshold SAD. Conclusions: Although revealing a strong association between SAD and PDAG, our results argue against a specific SAD-PDAG relationship. PDAG was neither a specific outcome nor a complete mediator variable of SAD. Copyright (c) 2007 S. Karger AG, Basel.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Klinische Psychologie und Epidemiologie (Lieb)
UniBasel Contributors:Lieb, Roselind
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:25 Oct 2017 05:53
Deposited On:22 Mar 2012 13:43

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