Pre-transplant Social Adaptability Index and clinical outcomes in renal transplantation - The Swiss Transplant Cohort Study

Denhaerynck, Kris and Goldfarb-Rumyantzev, Alexander S. and Sandhu, Gurprataap and Beckmann, Sonja and Huynh-Do, Uyen and Binet, Isabelle and De Geest, Sabina and Psychosocial Interest Group, and Swiss Transplant Cohort Study, . (2021) Pre-transplant Social Adaptability Index and clinical outcomes in renal transplantation - The Swiss Transplant Cohort Study. Clinical Transplantation, 35 (4). e14218.

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Official URL: https://edoc.unibas.ch/82194/

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The impact of pre-transplant social determinants of health on post-transplant outcomes remains understudied. In the US, poor clinical outcomes are associated with underprivileged status, as assessed by the Social Adaptability Index (SAI), a composite score of education, employment status, marital status, household income, and substance abuse. Using data from the Swiss Transplant Cohort Study (STCS), we determined the SAI's predictive value regarding two post-transplant outcomes: all-cause mortality and return to dialysis.; Between 2012 and 2018, we included adult renal transplant patients (aged ≥18 years) with pre-transplant assessment SAI scores, calculated from a STCS Psychosocial Questionnaire. Time to all-cause mortality and return to dialysis were predicted using Cox regression.; Of 1238 included patients (mean age: 53.8±13.2 years; 37.9% female; median follow-up time: 4.4 years (IQR: 2.7)), 93 (7.5%) died and 57 (4.6%) returned to dialysis. The SAI's hazard ratio was 0.94 (95%CI: 0.88-1.01; p=0.09) for mortality and 0.93 (95%CI: 0.85-1.02; p=0.15) for return to dialysis.; In contrast to most published studies on social deprivation, analysis of this Swiss sample detected no significant association between SAI score and mortality or return to dialysis.
Faculties and Departments:03 Faculty of Medicine > Departement Public Health > Institut für Pflegewissenschaft
UniBasel Contributors:Denhaerynck, Kris and Beckmann, Sonja and De Geest, Sabina M.
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:06 Jan 2022 02:30
Deposited On:18 Jun 2021 07:41

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