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The Swiss Paediatric Airway Cohort (SPAC)

Pedersen, Eva S. L. and de Jong, Carmen C. M. and Ardura-Garcia, Cristina and Barben, Juerg and Casaulta, Carmen and Frey, Urs and Jochmann, Anja and Latzin, Philipp and Moeller, Alexander and Regamey, Nicolas and Singer, Florian and Spycher, Ben and Sutter, Oliver and Goutaki, Myrofora and Kuehni, Claudia E.. (2018) The Swiss Paediatric Airway Cohort (SPAC). ERJ open research, 4 (4). 00050-2018.

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Abstract

Chronic respiratory symptoms, such as cough, wheeze and dyspnoea, are common in children; however, most research has, with the exception of a few large-scale clinical cohort studies, been performed in the general population or in small, highly-selected samples. The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians for recurrent conditions, such as wheeze and cough, and exercise-related respiratory problems. The SPAC is an observational study and baseline assessment includes standardised questionnaires for families and data extracted from hospital records, including results of clinically indicated investigations, diagnoses and treatments. Outcomes are assessed through annual questionnaires, monthly symptom reporting; via; mobile phone and follow-up visits. The SPAC will address important questions about clinical phenotypes, diagnosis, treatment, and the short- and long-term prognosis of common respiratory problems in children. The cohort currently consists of 347 patients from four major hospitals (Bern, Zurich, Basel and Lucerne), with 70-80 additional patients joining each month. More centres will join and the target sample size is a minimum of 3000 patients. The SPAC will provide real-life data on children visiting the Swiss healthcare system for common respiratory problems and will provide a research platform for health services research and nested clinical and translational studies.
Faculties and Departments:03 Faculty of Medicine > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) > P├Ądiatrie (Frey)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Kinder- und Jugendheilkunde (Klinik) > Kinder- und Jugendheilkunde (UKBB) > P├Ądiatrie (Frey)
UniBasel Contributors:Frey, Urs Peter
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:European Respiratory Society
ISSN:2312-0541
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
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Last Modified:03 Mar 2021 10:00
Deposited On:03 Mar 2021 10:00

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