Lymphoid Tissue in Teleost Gills: Variations on a Theme

Rességuier, Julien and Dalum, Alf S. and Pasquier, Louis Du and Zhang, Yaqing and Koppang, Erling Olaf and Boudinot, Pierre and Wiegertjes, Geert F.. (2020) Lymphoid Tissue in Teleost Gills: Variations on a Theme. Biology, 9 (6). p. 127.

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Official URL: https://edoc.unibas.ch/81323/

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In bony fish, the gill filaments are essential for gas exchanges, but also are vulnerable to infection by water-borne microorganisms. Omnipresent across fish, gill-associated lymphoid tissues (GIALT) regulate interactions with local microbiota and halt infection by pathogens. A special GIALT structure has recently been found in Salmonids, the interbranchial lymphoid tissue (ILT). However, the structural variation of GIALT across bony fish remains largely unknown. Here, we show how this critical zone of interaction evolved across fishes. By labeling a conserved T-cell epitope on tissue sections, we find that several basal groups of teleosts possess typical ILT, while modern teleosts have lymphoepithelium of different shape and size at the base of primary gill filaments. Within Cypriniformes, neither body size variation between two related species, zebrafish and common carp, nor morphotype variation, did have a drastic effect on the structure of ILT. Thereby this study is the first to describe the presence of ILT in zebrafish. The ILT variability across fish orders seems to represent different evolutionary solutions to balancing trade-offs between multiple adaptations of jaws and pharyngeal region, and immune responses. Our data point to a wide structural variation in gill immunity between basal groups and modern teleosts.
Faculties and Departments:05 Faculty of Science > Departement Umweltwissenschaften > Ehemalige Einheiten Umweltwissenschaften > Evolution des Immunsystems (Du Pasquier)
UniBasel Contributors:Du Pasquier, Louis
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Feb 2021 08:31
Deposited On:27 Jan 2021 11:29

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