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A typology of cannabis-related problems among individuals with repeated illegal drug use in the first three decades of life : evidence for heterogeneity and different treatment needs

Wittchen, H.-U. and Behrendt, S. and Höfler, M. and Perkonigg, A. and Rehm, J. and Lieb, R. and Beesdo, K.. (2009) A typology of cannabis-related problems among individuals with repeated illegal drug use in the first three decades of life : evidence for heterogeneity and different treatment needs. Drug and alcohol dependence, Vol. 102, H. 1-3. pp. 151-157.

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Official URL: http://edoc.unibas.ch/dok/A5253163

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Abstract

Background: Cannabis use (CU) and disorders (CUD) are highly prevalent among adolescents and Young adults. We aim to identify clinically meaningful Latent classes Of Users of cannabis and other illegal substances with distinct problem profiles. Methods: N=3021 Community subjects aged 14-24 at baseline were followed-up over a period ranging Lip to 10 years. Substance Use (SU) and disorders (SUD) were assessed with the DSM-IV/M-CIDI. Latent class analysis (LCA) was conducted with a subset of N = 1089 Subjects with repeated illegal SU. The variables entered in the LCA were CU-related problems, CUD, other SUD, and other mental disorders. Results: Four latent classes were identified: "Unproblematic CU" (class 1: 59.2%), "Primary alcohol use disorders" (class 2: 14.4%), "Delinquent cannabisi/alcohol DSM-IV-abuse" (class 3: 17.9%), "CUD with multiple problems" (class 4: 8.5%). Range and level of CU-related problems were highest in classes 3 and 4. Comorbidity with other mental disorders was highest in classes 2 and 4. The probability of alcohol disorders and unmet treatment needs was considerable in classes 2-4. Conclusion: While the majority of Subjects with repeated illegal SU did not experience notable problems over the 10-year period, a large minority (40.8%) experienced problematic outcomes, distinguished by clinically meaningful profiles, The data underline the need for specifically tailored interventions for adolescents with problematic CU and highlight the potentially important role of alcohol and other mental disorders.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Klinische Psychologie und Epidemiologie (Lieb)
UniBasel Contributors:Lieb, Roselind
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:Elsevier
ISSN:0376-8716
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:24
Deposited On:22 Mar 2012 13:42

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