Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population

Gkantidis, Nikolaos and Katib, Hattan and Oeschger, Elias and Karamolegkou, Marina and Topouzelis, Nikolaos and Kanavakis, Georgios. (2017) Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population. Archives of oral biology, 79. pp. 42-47.

Full text not available from this repository.

Official URL: https://edoc.unibas.ch/80658/

Downloads: Statistics Overview


The aim of this study is to explore patterns of non-syndromic permanent tooth agenesis in a large orthodontic patient group.; A record review was performed in various orthodontic clinics to identify white patients with non-syndromic permanent tooth agenesis, excluding 3rd molars. Four hundred and fourteen subjects fulfilled the inclusion criteria.; In the 414 subjects with tooth agenesis, approximately 70% presented 1-2 missing teeth. Symmetric agenesis patterns were often observed in the sample (by jaw, by side, or crossed quadrants), with prevalence approaching 30% for cases with contralateral tooth agenesis within a jaw. In cases with 1 or 2 missing teeth, from the total number of potential tooth agenesis patterns in the sample, a certain part was evident, limiting the variation to 27.8% (44/158). In the entire sample, both in the maxilla and the mandible a certain incisor/premolar agenesis phenotype was observed in 59.0% of cases in isolated form.; Although there was variation in the tooth agenesis patterns, our findings suggest the involvement of particular genetic, epigenetic, and/or environmental factors in the formation of the entire dentition, which often lead to specific tooth agenesis phenotypes in cases where this process is disrupted. The present study provides a comprehensive categorization of orthodontic cases with tooth agenesis and can assist in planning future epidemiological and genetic studies.
Faculties and Departments:03 Faculty of Medicine > Departement Zahnmedizin > Klinik Kieferorthopädie Kinderzahnmedizin
UniBasel Contributors:Kanavakis, Georgios M.
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:20 Apr 2021 14:10
Deposited On:20 Apr 2021 14:10

Repository Staff Only: item control page