Bile acid and xenobiotic transporters in liver

Stieger, B. and Meier, P. J.. (1998) Bile acid and xenobiotic transporters in liver. Current opinion in cell biology, Vol. 10, H. 4. pp. 462-467.

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Official URL: http://edoc.unibas.ch/dok/A5261706

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Identification of transporters involved in bile formation in liver is rapidly progressing. It is now clear that these transporters are also important in drug disposition in the body. Significant recent advances include the cloning of an ATP-dependent bile acid transporter, related to the p-glycoprotein family, in the canalicular plasma membrane of hepatocytes. In addition, liver transporter genes responsible for hereditary forms of cholestatic liver disease have been identified and found to belong to the superfamily of ATP-binding cassette proteins.
Faculties and Departments:11 Rektorat und Verwaltung > Vizerektorat Forschung
UniBasel Contributors:Meier-Abt, Peter J.
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:29 Jan 2016 09:18
Deposited On:22 Mar 2012 13:41

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