2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0

Ryom, L. and Cotter, A. and De Miguel, R. and Béguelin, Charles and Podlekareva, D. and Arribas, J. R. and Marzolini, Catia and Mallon, Pgm and Rauch, A. and Kirk, Ole and Molinari, Jesus M. and Guaraldi, G. and Winston, A. and Bhagani, S. and Cinque, Paola and Kowalska, Joanna D. and Collins, S. and Battegay, Manuel and Eacs Governing Board, . (2020) 2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0. HIV Medicine, 21 (10). pp. 617-624.

Full text not available from this repository.

Official URL: https://edoc.unibas.ch/78774/

Downloads: Statistics Overview


The European AIDS Clinical Society (EACS) Guidelines cover key aspects of HIV management with major updates every two years.; The 2019 Guidelines were extended with a new section focusing on drug-drug interactions and other prescribing issues in people living with HIV (PLWH). The recommendations for treatment-naïve PLWH were updated with four preferred regimens favouring unboosted integrase inhibitors. A two-drug regimen with dolutegravir and lamivudine, and a three-drug regimen including doravirine were also added to the recommended initial regimens. Lower thresholds for hypertension were expanded to all PLWH and for cardiovascular disease prevention, the 10-year predicted risk threshold for consideration of antiretroviral therapy (ART) modification was lowered from 20% to 10%. Frailty and obesity were added as new topics. It was specified to use urine albumin to creatinine ratio to screen for glomerular disease and urine protein to creatinine ratio for tubular diseases, and thresholds were streamlined with the Kidney Disease: Improving Global Outcomes (KDIGO) recommendations. Hepatitis C virus (HCV) treatment recommendations were split into preferred and alternative treatment options. The algorithm for management of recently acquired HCV infection was updated and includes recommendations for early chronic infection management. Treatment of resistant tuberculosis (TB) was streamlined with the World Health Organization (WHO) recommendations, and new tables on immune reconstitution inflammatory syndrome, on when to start ART in the presence of opportunistic infections and on TB drug dosing were included.; The EACS Guidelines underwent major revisions of all sections in 2019. They are available in four different formats including a new interactive web-based version and are translated into Chinese, French, German, Japanese, Portuguese, Russian and Spanish.
Faculties and Departments:03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Infektiologie > Infektiologie (Battegay M)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Infektiologie > Infektiologie (Battegay M)
UniBasel Contributors:Marzolini, Catia
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:29 Dec 2020 08:40
Deposited On:29 Dec 2020 08:40

Repository Staff Only: item control page