Characterization of Ablated Bone and Muscle for Long-Pulsed Laser Ablation in Dry and Wet Conditions

Nguendon Kenhagho, Herve and Shevchik, Sergey and Saeidi, Fatemeh and Faivre, Neige and Meylan, Bastian and Rauter, Georg and Guzman, Raphael and Cattin, Philippe and Wasmer, Kilian and Zam, Azhar. (2019) Characterization of Ablated Bone and Muscle for Long-Pulsed Laser Ablation in Dry and Wet Conditions. Materials, 12 (8). p. 1338.

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Official URL: https://edoc.unibas.ch/78667/

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Smart laser technologies are desired that can accurately cut and characterize tissues, such as bone and muscle, with minimal thermal damage and fast healing. Using a long-pulsed laser with a 0.5-10 ms pulse width at a wavelength of 1.07 mu m, we investigated the optimum laser parameters for producing craters with minimal thermal damage under both wet and dry conditions. In different tissues (bone and muscle), we analyzed craters of various morphologies, depths, and volumes. We used a two-way Analysis of Variance (ANOVA) test to investigate whether there are significant differences in the ablation efficiency in wet versus dry conditions at each level of the pulse energy. We found that bone and muscle tissue ablated under wet conditions produced fewer cracks and less thermal damage around the craters than under dry conditions. In contrast to muscle, the ablation efficiency of bone under wet conditions was not higher than under dry conditions. Tissue differentiation was carried out based on measured acoustic waves. A Principal Component Analysis of the measured acoustic waves and Mahalanobis distances were used to differentiate bone and muscle under wet conditions. Bone and muscle ablated in wet conditions demonstrated a classification error of less than 6.66% and 3.33%, when measured by a microphone and a fiber Bragg grating, respectively.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedical Engineering > Laser and Robotics > Bio-Inspired Robots for Medicine-Lab (Rauter)
UniBasel Contributors:Rauter, Georg
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:01 Oct 2020 06:58
Deposited On:01 Oct 2020 06:58

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