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Toward a single dose cure for Buruli ulcer

Thomas, Sangeeta S. and Kalia, Nitin Pal and Ruf, Marie-Thérèse and Pluschke, Gerd and Pethe, Kevin. (2020) Toward a single dose cure for Buruli ulcer. Antimicrobial agents and chemotherapy, 64 (9). e00727-20.

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Official URL: https://edoc.unibas.ch/78510/

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Abstract

A single dose of Q203 (Telacebec), a phase 2 clinical candidate for tuberculosis, eradicates; Mycobacterium ulcerans; in a mouse model of Buruli ulcer infection without relapse up to 19 weeks posttreatment. Clinical use of Q203 may dramatically simplify the clinical management of Buruli ulcer, a neglected mycobacterial disease.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medicine (MED) > Diagnostic (Nickel)
UniBasel Contributors:Ruf, Marie-Therese
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:0066-4804
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:19 Dec 2022 08:04
Deposited On:19 Dec 2022 08:04

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