Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy

Weber, Walter P. and Haug, Martin and Kurzeder, Christian and Bjelic-Radisic, Vesna and Koller, Rupert and Reitsamer, Roland and Fitzal, Florian and Biazus, Jorge and Brenelli, Fabricio and Urban, Cicero and Paulinelli, Régis Resende and Blohmer, Jens-Uwe and Heil, Jörg and Hoffmann, Jürgen and Matrai, Zoltan and Catanuto, Giuseppe and Galimberti, Viviana and Gentilini, Oreste and Barry, Mitchel and Hadar, Tal and Allweis, Tanir M. and Olsha, Oded and Cardoso, Maria João and Gouveia, Pedro F. and Rubio, Isabel T. and de Boniface, Jana and Svensjö, Tor and Bucher, Susanne and Dubsky, Peter and Farhadi, Jian and Fehr, Mathias K. and Fulco, Ilario and Ganz-Blättler, Ursula and Günthert, Andreas and Harder, Yves and Hauser, Nik and Kappos, Elisabeth A. and Knauer, Michael and Landin, Julia and Mechera, Robert and Meani, Francesco and Montagna, Giacomo and Ritter, Mathilde and Saccilotto, Ramon and Schwab, Fabienne D. and Steffens, Daniel and Tausch, Christoph and Zeindler, Jasmin and Soysal, Savas D. and Lohsiriwat, Visnu and Kovacs, Tibor and Tansley, Anne and Wyld, Lynda and Romics, Laszlo and El-Tamer, Mahmoud and Pusic, Andrea L. and Sacchini, Virgilio and Gnant, Michael. (2018) Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy. Breast cancer research and treatment, 172 (3). pp. 523-537.

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Official URL: https://edoc.unibas.ch/78490/

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Indications for nipple-sparing mastectomy (NSM) have broadened to include the risk reducing setting and locally advanced tumors, which resulted in a dramatic increase in the use of NSM. The Oncoplastic Breast Consortium consensus conference on NSM and immediate reconstruction was held to address a variety of questions in clinical practice and research based on published evidence and expert panel opinion.; The panel consisted of 44 breast surgeons from 14 countries across four continents with a background in gynecology, general or reconstructive surgery and a practice dedicated to breast cancer, as well as a patient advocate. Panelists presented evidence summaries relating to each topic for debate during the in-person consensus conference. The iterative process in question development, voting, and wording of the recommendations followed the modified Delphi methodology.; Consensus recommendations were reached in 35, majority recommendations in 24, and no recommendations in the remaining 12 questions. The panel acknowledged the need for standardization of various aspects of NSM and immediate reconstruction. It endorsed several oncological contraindications to the preservation of the skin and nipple. Furthermore, it recommended inclusion of patients in prospective registries and routine assessment of patient-reported outcomes. Considerable heterogeneity in breast reconstruction practice became obvious during the conference.; In case of conflicting or missing evidence to guide treatment, the consensus conference revealed substantial disagreement in expert panel opinion, which, among others, supports the need for a randomized trial to evaluate the safest and most efficacious reconstruction techniques.
Faculties and Departments:03 Faculty of Medicine
UniBasel Contributors:Fulco, Ilario
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:23 Sep 2020 06:17
Deposited On:23 Sep 2020 06:17

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