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Secreted microRNA data from the parasitic filarial nematode Acanthocheilonema viteae

Soichot, Julien and Endriss, Yvette and Marti, Hanspeter and Tritten, Lucienne. (2020) Secreted microRNA data from the parasitic filarial nematode Acanthocheilonema viteae. Data in brief, 29. p. 105334.

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Official URL: https://edoc.unibas.ch/76114/

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Abstract

microRNAs (miRNAs) are an abundant class of non-coding RNA species with important regulatory roles in gene expression at the posttranscriptional level. The helminth; Acanthocheilonema viteae; serves as model organism for research on parasitic filarial nematodes. Total RNA secreted or excreted; in vitro; by 1500 adult female and male; A. viteae; over 3 weeks was isolated from culture media previously processed by differential ultracentrifugation. miRNA sequencing revealed the presence of 360 unique miRNA candidates released by adult; A. viteae in vitro; . Among them, 74 high-confidence unique miRNAs; ,; as well as several potential novel miRNA candidates were discovered. A large proportion of the sequenced miRNA candidates appeared differentially expressed between the male and female samples based on normalized copy count. The presence of extracellular vesicles, often rich in miRNAs, could not be confirmed unambiguously by transmission electron microscopy.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Diagnostic (Marti)
UniBasel Contributors:Endriss, Yvette and Marti, Hanspeter
Item Type:Article, refereed
Article Subtype:Research Article
ISSN:2352-3409
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:27 Mar 2020 07:29
Deposited On:27 Mar 2020 07:29

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