Crystal structure of an empty capsid of turnip yellow mosaic virus

van Roon, Anne-Marie M. and Bink, Hugo H. J. and Plaisier, Jasper R. and Pleij, Cornelis W. A. and Abrahams, Jan Pieter and Pannu, Navraj S.. (2004) Crystal structure of an empty capsid of turnip yellow mosaic virus. Journal of Molecular Biology, 341 (5). pp. 1205-1214.

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Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Structural Biology & Biophysics > Nano-diffraction of Biological Specimen (Abrahams)
UniBasel Contributors:Abrahams, Jan Pieter
Item Type:Article, refereed
Article Subtype:Research Article
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:05 Nov 2020 16:05
Deposited On:05 Nov 2020 16:05

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